PT1776142E - Anticorpos antagonistas de il-17 - Google Patents

Anticorpos antagonistas de il-17 Download PDF

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Publication number
PT1776142E
PT1776142E PT05770286T PT05770286T PT1776142E PT 1776142 E PT1776142 E PT 1776142E PT 05770286 T PT05770286 T PT 05770286T PT 05770286 T PT05770286 T PT 05770286T PT 1776142 E PT1776142 E PT 1776142E
Authority
PT
Portugal
Prior art keywords
antagonist antibodies
antibody
human
disorder
heavy
Prior art date
Application number
PT05770286T
Other languages
English (en)
Portuguese (pt)
Inventor
Hermann Gram
Franco E Di Padova
Hans Hofstetter
Margit Jeschke
Jean-Michel Rondeau
Wim Van Den Berg
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32982602&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1776142(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT1776142E publication Critical patent/PT1776142E/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT05770286T 2004-08-05 2005-08-04 Anticorpos antagonistas de il-17 PT1776142E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0417487.6A GB0417487D0 (en) 2004-08-05 2004-08-05 Organic compound

Publications (1)

Publication Number Publication Date
PT1776142E true PT1776142E (pt) 2011-10-06

Family

ID=32982602

Family Applications (4)

Application Number Title Priority Date Filing Date
PT05770286T PT1776142E (pt) 2004-08-05 2005-08-04 Anticorpos antagonistas de il-17
PT151560299T PT2902039T (pt) 2004-08-05 2005-08-04 Anticorpos antagonísticos de il-17
PT101747251T PT2366405E (pt) 2004-08-05 2005-08-04 Anticorpos antagonistas de il-17
PT101751501T PT2364729E (pt) 2004-08-05 2005-08-04 Anticorpos antagonísticos de il-17

Family Applications After (3)

Application Number Title Priority Date Filing Date
PT151560299T PT2902039T (pt) 2004-08-05 2005-08-04 Anticorpos antagonísticos de il-17
PT101747251T PT2366405E (pt) 2004-08-05 2005-08-04 Anticorpos antagonistas de il-17
PT101751501T PT2364729E (pt) 2004-08-05 2005-08-04 Anticorpos antagonísticos de il-17

Country Status (40)

Country Link
US (9) US7807155B2 (2)
EP (5) EP2366405B1 (2)
JP (1) JP4682200B2 (2)
KR (2) KR100852523B1 (2)
CN (1) CN101001645B (2)
AR (1) AR050200A1 (2)
AT (1) ATE517924T1 (2)
AU (2) AU2005268857C1 (2)
BE (1) BE2015C041I2 (2)
BR (3) BR122018075556B1 (2)
CA (1) CA2573586C (2)
CY (6) CY1111963T1 (2)
DK (4) DK2902039T3 (2)
EC (1) ECSP077198A (2)
ES (4) ES2367440T7 (2)
FR (1) FR15C0048I2 (2)
GB (1) GB0417487D0 (2)
HK (1) HK1256639A1 (2)
HR (3) HRP20110758T4 (2)
HU (4) HUE025815T2 (2)
IL (1) IL180717A (2)
LT (3) LT2902039T (2)
LU (2) LU92768I2 (2)
MA (1) MA28982B1 (2)
MX (1) MX2007001338A (2)
MY (1) MY144925A (2)
NL (1) NL300749I2 (2)
NO (9) NO336279B1 (2)
NZ (1) NZ552658A (2)
PE (1) PE20060418A1 (2)
PL (4) PL2364729T6 (2)
PT (4) PT1776142E (2)
RU (2) RU2426741C3 (2)
SG (1) SG155186A1 (2)
SI (4) SI1776142T1 (2)
TN (1) TNSN07034A1 (2)
TR (1) TR201808057T4 (2)
TW (1) TWI359153B (2)
WO (1) WO2006013107A1 (2)
ZA (1) ZA200700242B (2)

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PL2364729T6 (pl) 2016-06-30
PT2366405E (pt) 2015-06-30
EP2902039A1 (en) 2015-08-05
LTC1776142I2 (lt) 2022-07-11
CN101001645A (zh) 2007-07-18
HRP20110758T1 (en) 2011-11-30
TR201808057T4 (tr) 2018-06-21
NO2015023I1 (no) 2015-11-02
ES2677245T3 (es) 2018-07-31
ES2367440T3 (es) 2011-11-03
MX2007001338A (es) 2008-03-11
NO337286B1 (no) 2016-02-29
AU2010201689B2 (en) 2011-09-29
NZ552658A (en) 2009-11-27
CY2015030I2 (el) 2017-11-14
SI2902039T1 (en) 2018-07-31
KR20080029018A (ko) 2008-04-02
ES2487533T7 (es) 2015-07-14
PE20060418A1 (es) 2006-06-15
US9765140B2 (en) 2017-09-19
SI2364729T1 (sl) 2014-08-29
GB0417487D0 (en) 2004-09-08
NO2022026I1 (no) 2022-06-24
RU2007108067A (ru) 2008-09-10
FR15C0048I2 (fr) 2015-11-20
RU2426741C3 (ru) 2017-11-15
HK1207559A1 (en) 2016-02-05
ES2367440T9 (es) 2021-04-28
US20190270804A1 (en) 2019-09-05
ECSP077198A (es) 2007-02-28
HRP20150480T1 (hr) 2015-07-17
DK2366405T3 (en) 2015-05-11
US20120107325A1 (en) 2012-05-03
US20100215666A1 (en) 2010-08-26
HK1256639A1 (en) 2019-09-27
EP1776142A1 (en) 2007-04-25
CA2573586C (en) 2013-06-25
US20250122277A1 (en) 2025-04-17
AU2005268857C1 (en) 2012-01-19
HUS1500037I1 (hu) 2017-10-30
BE2015C041I2 (2) 2024-10-08
AU2005268857A1 (en) 2006-02-09
NO348010B1 (no) 2024-06-17
PT2902039T (pt) 2018-07-17
SI1776142T1 (sl) 2011-11-30
NO20070985L (no) 2007-03-30
BRPI0513078B8 (pt) 2019-08-27
DK1776142T3 (da) 2011-10-31
CN101001645B (zh) 2012-09-05
CY1116256T1 (el) 2017-02-08
US20140079719A1 (en) 2014-03-20
NO20151787L (no) 2006-02-06
SG155186A1 (en) 2009-09-30
BR122018075556B1 (pt) 2022-10-18
EP2366405B1 (en) 2015-02-25
PL1776142T3 (pl) 2011-12-30
BRPI0513078C1 (pt) 2021-05-25

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