CY1120723T1 - Ανταγωνιστικα αντισωματα il-17 - Google Patents

Ανταγωνιστικα αντισωματα il-17

Info

Publication number
CY1120723T1
CY1120723T1 CY181100727T CY181100727T CY1120723T1 CY 1120723 T1 CY1120723 T1 CY 1120723T1 CY 181100727 T CY181100727 T CY 181100727T CY 181100727 T CY181100727 T CY 181100727T CY 1120723 T1 CY1120723 T1 CY 1120723T1
Authority
CY
Cyprus
Prior art keywords
competitive antibodies
antibody
human
disease
heavy
Prior art date
Application number
CY181100727T
Other languages
English (en)
Inventor
Padova Franco E Di
Hermann Gram
Hans Hofstetter
Margit Jeschke
Jean-Michel Rondeau
Den Berg Wim Van
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32982602&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1120723(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CY1120723T1 publication Critical patent/CY1120723T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Abstract

Παρέχεται ένα μόριο πρόσδεσης IL-17, συγκεκριμένα ένα αντίσωμα στην ανθρώπινη IL-17, κατά προτίμηση ένα ανθρώπινο αντίσωμα στην IL-17, όπου οι υπερμεταβλητές περιοχές των βαριών και των ελαφριών αλυσίδων έχουν ακολουθίες αμινοξέος όπως ορίστηκαν, για χρήση στη θεραπεία μιας νόσου ή διαταραχής που προκαλείται από την IL-17, π.χ. ρευματοειδή αρθρίτιδα.
CY181100727T 2004-08-05 2018-07-11 Ανταγωνιστικα αντισωματα il-17 CY1120723T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0417487.6A GB0417487D0 (en) 2004-08-05 2004-08-05 Organic compound
EP10174725.1A EP2366405B1 (en) 2004-08-05 2005-08-04 IL-17 antagonistic antibodies
EP05770286.2A EP1776142B9 (en) 2004-08-05 2005-08-04 Il-17 antagonistic antibodies

Publications (1)

Publication Number Publication Date
CY1120723T1 true CY1120723T1 (el) 2019-12-11

Family

ID=32982602

Family Applications (6)

Application Number Title Priority Date Filing Date
CY20111100936T CY1111963T1 (el) 2004-08-05 2011-09-27 Ανταγωνιστικα αντισωματα il-17
CY20141100628T CY1115444T1 (el) 2004-08-05 2014-08-08 Ανταγωνιστικα αντισωματα il-17
CY20151100401T CY1116256T1 (el) 2004-08-05 2015-05-07 Il-17 ανταγωνιστικα αντισωματα
CY2015030C CY2015030I2 (el) 2004-08-05 2015-07-10 Ανταγωνιστικα αντισωματα il-17
CY181100727T CY1120723T1 (el) 2004-08-05 2018-07-11 Ανταγωνιστικα αντισωματα il-17
CY2018027C CY2018027I1 (el) 2004-08-05 2018-10-10 Ανταγωνιστικα αντισωματα il-17

Family Applications Before (4)

Application Number Title Priority Date Filing Date
CY20111100936T CY1111963T1 (el) 2004-08-05 2011-09-27 Ανταγωνιστικα αντισωματα il-17
CY20141100628T CY1115444T1 (el) 2004-08-05 2014-08-08 Ανταγωνιστικα αντισωματα il-17
CY20151100401T CY1116256T1 (el) 2004-08-05 2015-05-07 Il-17 ανταγωνιστικα αντισωματα
CY2015030C CY2015030I2 (el) 2004-08-05 2015-07-10 Ανταγωνιστικα αντισωματα il-17

Family Applications After (1)

Application Number Title Priority Date Filing Date
CY2018027C CY2018027I1 (el) 2004-08-05 2018-10-10 Ανταγωνιστικα αντισωματα il-17

Country Status (39)

Country Link
US (8) US7807155B2 (el)
EP (5) EP2366405B1 (el)
JP (1) JP4682200B2 (el)
KR (2) KR20080029018A (el)
CN (1) CN101001645B (el)
AR (1) AR050200A1 (el)
AT (1) ATE517924T1 (el)
AU (2) AU2005268857C1 (el)
BR (3) BR122017009404B1 (el)
CA (1) CA2573586C (el)
CY (6) CY1111963T1 (el)
DK (4) DK2366405T3 (el)
EC (1) ECSP077198A (el)
ES (4) ES2536228T3 (el)
FR (1) FR15C0048I2 (el)
GB (1) GB0417487D0 (el)
HK (3) HK1101277A1 (el)
HR (3) HRP20110758T4 (el)
HU (4) HUE025815T2 (el)
IL (1) IL180717A (el)
LT (3) LT2902039T (el)
LU (2) LU92768I2 (el)
MA (1) MA28982B1 (el)
MX (1) MX2007001338A (el)
MY (1) MY144925A (el)
NL (1) NL300749I2 (el)
NO (9) NO336279B1 (el)
NZ (1) NZ552658A (el)
PE (1) PE20060418A1 (el)
PL (4) PL1776142T4 (el)
PT (4) PT2366405E (el)
RU (2) RU2426741C3 (el)
SG (1) SG155186A1 (el)
SI (4) SI2902039T1 (el)
TN (1) TNSN07034A1 (el)
TR (1) TR201808057T4 (el)
TW (1) TWI359153B (el)
WO (1) WO2006013107A1 (el)
ZA (1) ZA200700242B (el)

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