PT1150746E - A utilizacao de derivados de 4-h-1-benzopiran-4-ona como inibidores da proliferacao celular do musculo liso - Google Patents

A utilizacao de derivados de 4-h-1-benzopiran-4-ona como inibidores da proliferacao celular do musculo liso

Info

Publication number
PT1150746E
PT1150746E PT00909918T PT00909918T PT1150746E PT 1150746 E PT1150746 E PT 1150746E PT 00909918 T PT00909918 T PT 00909918T PT 00909918 T PT00909918 T PT 00909918T PT 1150746 E PT1150746 E PT 1150746E
Authority
PT
Portugal
Prior art keywords
prolapse
benzopyran
inhibitors
derivatives
smooth muscle
Prior art date
Application number
PT00909918T
Other languages
English (en)
Portuguese (pt)
Inventor
Jennifer A Dumont
Patterson Winston Campbell
Original Assignee
Univ Texas
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas, Aventis Pharma Inc filed Critical Univ Texas
Publication of PT1150746E publication Critical patent/PT1150746E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT00909918T 1999-02-01 2000-01-18 A utilizacao de derivados de 4-h-1-benzopiran-4-ona como inibidores da proliferacao celular do musculo liso PT1150746E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24338099A 1999-02-01 1999-02-01
US09/468,665 US6399633B1 (en) 1999-02-01 1999-12-21 Use of 4-H-1-benzopryan-4-one derivatives as inhibitors of smooth muscle cell proliferation

Publications (1)

Publication Number Publication Date
PT1150746E true PT1150746E (pt) 2004-12-31

Family

ID=22918541

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00909918T PT1150746E (pt) 1999-02-01 2000-01-18 A utilizacao de derivados de 4-h-1-benzopiran-4-ona como inibidores da proliferacao celular do musculo liso

Country Status (38)

Country Link
US (1) US6399633B1 (enExample)
EP (1) EP1150746B1 (enExample)
JP (1) JP4755759B2 (enExample)
KR (1) KR100793047B1 (enExample)
CN (1) CN1219556C (enExample)
AP (1) AP1469A (enExample)
AR (1) AR042569A1 (enExample)
AT (1) ATE275428T1 (enExample)
AU (1) AU777368B2 (enExample)
BG (1) BG65151B1 (enExample)
BR (1) BR0007911A (enExample)
CA (1) CA2360668C (enExample)
CR (1) CR6448A (enExample)
CZ (1) CZ300395B6 (enExample)
DE (1) DE60013555T2 (enExample)
DK (1) DK1150746T3 (enExample)
EA (1) EA004786B1 (enExample)
EE (1) EE04851B1 (enExample)
ES (1) ES2226792T3 (enExample)
HK (1) HK1042445B (enExample)
HR (1) HRP20010521A2 (enExample)
HU (1) HU229263B1 (enExample)
ID (1) ID30180A (enExample)
IL (1) IL144668A (enExample)
ME (1) MEP10508A (enExample)
NO (1) NO330512B1 (enExample)
NZ (1) NZ512822A (enExample)
OA (1) OA11755A (enExample)
PL (1) PL197693B1 (enExample)
PT (1) PT1150746E (enExample)
RS (1) RS50242B (enExample)
SI (1) SI1150746T1 (enExample)
SK (1) SK286747B6 (enExample)
TR (1) TR200102223T2 (enExample)
TW (1) TWI273907B (enExample)
UA (1) UA73110C2 (enExample)
WO (1) WO2000044362A2 (enExample)
ZA (1) ZA200105596B (enExample)

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Also Published As

Publication number Publication date
ES2226792T3 (es) 2005-04-01
CR6448A (es) 2004-03-17
US6399633B1 (en) 2002-06-04
JP4755759B2 (ja) 2011-08-24
AP2001002218A0 (en) 2001-09-30
CN1338958A (zh) 2002-03-06
CA2360668A1 (en) 2000-08-03
TR200102223T2 (tr) 2004-12-21
WO2000044362A2 (en) 2000-08-03
JP2002535356A (ja) 2002-10-22
CZ20012804A3 (cs) 2002-08-14
RS50242B (sr) 2009-07-15
OA11755A (en) 2005-07-19
AP1469A (en) 2005-09-26
CZ300395B6 (cs) 2009-05-06
ZA200105596B (en) 2002-10-07
PL197693B1 (pl) 2008-04-30
HU229263B1 (en) 2013-10-28
PL350735A1 (en) 2003-01-27
IL144668A0 (en) 2002-05-23
ID30180A (id) 2001-11-08
SK286747B6 (sk) 2009-04-06
DE60013555D1 (de) 2004-10-14
NO330512B1 (no) 2011-05-09
EE200100385A (et) 2002-12-16
EP1150746A2 (en) 2001-11-07
TWI273907B (en) 2007-02-21
KR100793047B1 (ko) 2008-01-10
YU54401A (sh) 2004-05-12
HRP20010521A2 (en) 2002-08-31
BR0007911A (pt) 2001-10-16
NO20013335D0 (no) 2001-07-05
WO2000044362A3 (en) 2001-04-05
SI1150746T1 (en) 2005-02-28
ATE275428T1 (de) 2004-09-15
EP1150746B1 (en) 2004-09-08
NO20013335L (no) 2001-09-25
BG65151B1 (bg) 2007-04-30
DK1150746T3 (da) 2005-01-10
HUP0200804A3 (en) 2004-03-29
HK1042445B (zh) 2006-01-13
KR20010093309A (ko) 2001-10-27
MEP10508A (en) 2010-06-10
NZ512822A (en) 2005-01-28
UA73110C2 (en) 2005-06-15
IL144668A (en) 2005-06-19
CN1219556C (zh) 2005-09-21
EA200100742A1 (ru) 2001-12-24
BG105751A (en) 2002-02-28
AU777368B2 (en) 2004-10-14
CA2360668C (en) 2009-03-17
EA004786B1 (ru) 2004-08-26
HUP0200804A2 (hu) 2002-12-28
AR042569A1 (es) 2005-06-29
HK1042445A1 (en) 2002-08-16
AU3209800A (en) 2000-08-18
DE60013555T2 (de) 2005-09-29
EE04851B1 (et) 2007-06-15
SK10862001A3 (sk) 2002-07-02

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