PT1144425E - Derivados de monossacaridos como inibidores de adesao celular - Google Patents
Derivados de monossacaridos como inibidores de adesao celularInfo
- Publication number
- PT1144425E PT1144425E PT00900087T PT00900087T PT1144425E PT 1144425 E PT1144425 E PT 1144425E PT 00900087 T PT00900087 T PT 00900087T PT 00900087 T PT00900087 T PT 00900087T PT 1144425 E PT1144425 E PT 1144425E
- Authority
- PT
- Portugal
- Prior art keywords
- monosacaridos
- inhibitors
- derivatives
- cell adhesion
- adhesion
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
- C07H9/04—Cyclic acetals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Transplantation (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22915599A | 1999-01-12 | 1999-01-12 | |
US09/411,357 US6329344B1 (en) | 1998-10-22 | 1999-10-01 | Derivatives of monosaccharides as cell adhesion inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1144425E true PT1144425E (pt) | 2004-10-29 |
Family
ID=26922990
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT00900087T PT1144425E (pt) | 1999-01-12 | 2000-01-10 | Derivados de monossacaridos como inibidores de adesao celular |
Country Status (29)
Country | Link |
---|---|
US (1) | US6329344B1 (pt) |
EP (1) | EP1144425B1 (pt) |
JP (1) | JP2002534529A (pt) |
CN (1) | CN1254478C (pt) |
AR (1) | AR033939A1 (pt) |
AT (1) | ATE269349T1 (pt) |
AU (1) | AU767948B2 (pt) |
BG (1) | BG105795A (pt) |
BR (1) | BR0007489A (pt) |
CA (1) | CA2359980A1 (pt) |
CO (1) | CO5170511A1 (pt) |
CZ (1) | CZ20012541A3 (pt) |
DE (1) | DE60011568T2 (pt) |
DK (1) | DK1144425T3 (pt) |
ES (1) | ES2223447T3 (pt) |
HK (1) | HK1041006B (pt) |
HR (1) | HRP20010527B1 (pt) |
HU (1) | HUP0200097A3 (pt) |
ID (1) | ID30259A (pt) |
IL (2) | IL144274A0 (pt) |
MA (1) | MA25679A1 (pt) |
MY (1) | MY122723A (pt) |
NZ (2) | NZ512851A (pt) |
PA (1) | PA8489601A1 (pt) |
PT (1) | PT1144425E (pt) |
SK (1) | SK284568B6 (pt) |
TR (1) | TR200102031T2 (pt) |
WO (1) | WO2000042053A1 (pt) |
YU (1) | YU50101A (pt) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL152397A (en) * | 2002-10-21 | 2009-02-11 | Hadasit Med Res Service | Compositions and compounds for the treatment of hyperglycemia |
AU2003202767A1 (en) * | 2003-02-12 | 2004-09-06 | Ranbaxy Laboratories Limited | Preparation of monosaccharide derivatives |
WO2004099229A1 (en) * | 2003-05-06 | 2004-11-18 | Ranbaxy Laboratories Limited | Process for the synthesis of base addition salts of 2,3-0-isopropylidene-1-0-substituted-5,6-dideoxy-5-n- (4-(2-hydroxy-2-oxoethyl)-phenylaminocarbonyl) amino-l-gulofuranosides |
CA2753318A1 (en) | 2003-05-30 | 2004-12-09 | Ranbaxy Laboratories Limited | Substituted pyrrole derivatives |
US20060004005A1 (en) * | 2003-09-25 | 2006-01-05 | Sattigeri Viswajanani J | Triazines derivatives as cell adhesion inhibitors |
WO2005092908A1 (en) * | 2004-03-18 | 2005-10-06 | Ranbaxy Laboratories Limited | Base addition salts of monosaccharides derivatives as inhibitors of airway hyper reactivity and airway inflammation |
WO2005092907A2 (en) * | 2004-03-26 | 2005-10-06 | Ranbaxy Laboratories Limited | Monosaccharide derivatives as anti-cancer and anti-inflammatory agents |
WO2005100373A2 (en) * | 2004-04-13 | 2005-10-27 | Ranbaxy Laboratories Limited | Monosaccharide derivatives as anti-cancer and anti-inflammatory agents |
US20090221515A1 (en) * | 2004-09-02 | 2009-09-03 | Viswajanani Jitendra Sattigeri | Monosaccharide derivatives |
US20100113371A9 (en) * | 2004-12-22 | 2010-05-06 | Ranbaxy Laboratories Limited Inc. | Derivatives Of Pentose Monosaccharides As Anti-Inflammatory Compounds |
EP1915160A2 (en) * | 2005-07-22 | 2008-04-30 | Ranbaxy Laboratories Limited | Derivatives of monosaccharides for the treatment of copd and allergic rhinitis |
US8026377B2 (en) | 2005-11-08 | 2011-09-27 | Ranbaxy Laboratories, Limited | Process for (3R, 5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid hemi calcium salt |
EP1842855A3 (en) * | 2006-03-29 | 2007-12-05 | Ranbaxy Laboratories Limited | Monosaccharide derivatives as anti-inflammatory and/or anti-cancer agents |
US7790689B2 (en) * | 2006-05-30 | 2010-09-07 | Ranbaxy Laboratories Limited | Monosaccharide derivatives |
EP1953170A1 (en) * | 2006-10-03 | 2008-08-06 | Ranbaxy Laboratories Limited | Monosaccharide derivatives as anti-inflammatory agents |
CN105367612A (zh) * | 2014-08-13 | 2016-03-02 | 中国药科大学 | 龙脷叶由来天然产物丁基2-脱氧-3,6-脱水-β-D-阿拉伯糖呋喃糖苷的全合成方法 |
US20220356150A1 (en) * | 2021-04-30 | 2022-11-10 | Evoco Limited | Biobased diisocyanates, and process for preparation of same |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2715121A (en) | 1950-09-09 | 1955-08-09 | American Home Prod | Alkyl sugar derivatives and their preparation |
US4056322A (en) | 1973-12-14 | 1977-11-01 | Strategic Medical Research Corporation | Preparation of ethers of monosaccharides |
DE2936240A1 (de) * | 1979-09-07 | 1981-03-26 | Bayer Ag, 51373 Leverkusen | Verfahren zur herstellung bekannter und neuer 6-amino-6-desoxy-2,3-0-isopropyliden-(alpha)-l-sorbofuranose-derivate sowie neue zwischenprodukte des verfahrens |
US4735934A (en) | 1981-02-17 | 1988-04-05 | Greenwich Pharmaceuticals Incorporated | Method of therapeutically treating a warm blooded animal afflicted with an autoimmune disease |
US4996195A (en) | 1989-01-09 | 1991-02-26 | Greenwich Pharmaceuticals Inc. | Derivatives of α,D-glucofuranose or α,D-allofuranose and intermediates for preparing these derivatives |
US5298494A (en) | 1989-01-09 | 1994-03-29 | Greenwich Pharmaceuticals Incorporated | Monosaccharides having anti-proliferation and anti-inflammatory activity, compositions and uses thereof |
US5010058A (en) | 1989-06-22 | 1991-04-23 | 501 Greenwich Pharmaceuticals Incorporated | 3,5,6-substituted derivatives of 1,2-O-isopropylidene-α,D-glucofuranose and intermediates for preparing these derivatives |
US5192746A (en) | 1990-07-09 | 1993-03-09 | Tanabe Seiyaku Co., Ltd. | Cyclic cell adhesion modulation compounds |
IL100833A0 (en) | 1991-02-20 | 1992-09-06 | Greenwich Pharma | Method for synthesis of ethereally substituted blocked monosaccharides |
US5360792A (en) | 1991-12-20 | 1994-11-01 | Greenwich Pharmaceuticals Incorporated | Anti-proliferative and anti-inflammatory compounds: 5- or 6-deoxy hexose monosaccharides having a saturated nitrogen-containing heterocycle at the 5- or 6-position bound through the nitrogen atom |
US5360794A (en) | 1992-08-03 | 1994-11-01 | Medicarb Inc. | Disubstituted and deoxy disubstituted derivatives of α-D-mannofuranosides and β-L-gulofuranosides having anti-inflammatory and anti-proliferative activity |
US5367062A (en) | 1992-08-21 | 1994-11-22 | Medicarb Inc. | Disubstituted and deoxydisubstituted derivatives of α-d-lyxofuranosides having anti-inflammatory and anti-proliferative activity |
US5508387A (en) * | 1993-08-04 | 1996-04-16 | Glycomed Incorporated | Selectin binding glycopeptides |
JPH09504522A (ja) * | 1993-10-12 | 1997-05-06 | グリコメド・インコーポレイテッド | 細胞接着インヒビターの同定に有用なグリコ−ペプチドのライブラリー |
US5637570A (en) | 1995-05-09 | 1997-06-10 | Chemora Pharmochem | Disubstituted and trisubstituted derivatives of 2,3:4,6-di-O-isopropylidene-α-L-xylo-2-hexulofuranosonic acid having anti-cancer, anti-inflammatory and anti-proliferative activity |
US5919769A (en) * | 1995-10-26 | 1999-07-06 | Kanebo, Ltd | Fucose derivatives, drugs containing the same as active ingredient, and intermediates for producing the same |
US5824657A (en) | 1997-03-18 | 1998-10-20 | Cubist Pharmaceuticals, Inc. | Aminoacyl sulfamides for the treatment of hyperproliferative disorders |
-
1999
- 1999-10-01 US US09/411,357 patent/US6329344B1/en not_active Expired - Fee Related
-
2000
- 2000-01-10 SK SK996-2001A patent/SK284568B6/sk unknown
- 2000-01-10 YU YU50101A patent/YU50101A/sh unknown
- 2000-01-10 HU HU0200097A patent/HUP0200097A3/hu unknown
- 2000-01-10 TR TR2001/02031T patent/TR200102031T2/xx unknown
- 2000-01-10 EP EP00900087A patent/EP1144425B1/en not_active Expired - Lifetime
- 2000-01-10 NZ NZ512851A patent/NZ512851A/xx unknown
- 2000-01-10 AT AT00900087T patent/ATE269349T1/de not_active IP Right Cessation
- 2000-01-10 IL IL14427400A patent/IL144274A0/xx not_active IP Right Cessation
- 2000-01-10 AR ARP000100085A patent/AR033939A1/es not_active Application Discontinuation
- 2000-01-10 CZ CZ20012541A patent/CZ20012541A3/cs unknown
- 2000-01-10 JP JP2000593620A patent/JP2002534529A/ja active Pending
- 2000-01-10 DE DE60011568T patent/DE60011568T2/de not_active Expired - Fee Related
- 2000-01-10 WO PCT/IB2000/000021 patent/WO2000042053A1/en active IP Right Grant
- 2000-01-10 ES ES00900087T patent/ES2223447T3/es not_active Expired - Lifetime
- 2000-01-10 NZ NZ527482A patent/NZ527482A/en unknown
- 2000-01-10 CN CNB008048428A patent/CN1254478C/zh not_active Expired - Fee Related
- 2000-01-10 ID IDW00200101521A patent/ID30259A/id unknown
- 2000-01-10 AU AU18860/00A patent/AU767948B2/en not_active Ceased
- 2000-01-10 CA CA002359980A patent/CA2359980A1/en not_active Abandoned
- 2000-01-10 BR BR0007489-6A patent/BR0007489A/pt not_active IP Right Cessation
- 2000-01-10 PT PT00900087T patent/PT1144425E/pt unknown
- 2000-01-10 DK DK00900087T patent/DK1144425T3/da active
- 2000-01-11 MY MYPI20000074A patent/MY122723A/en unknown
- 2000-01-12 PA PA20008489601A patent/PA8489601A1/es unknown
- 2000-01-12 CO CO00001165A patent/CO5170511A1/es not_active Application Discontinuation
-
2001
- 2001-07-11 IL IL144274A patent/IL144274A/en unknown
- 2001-07-12 MA MA26265A patent/MA25679A1/fr unknown
- 2001-07-12 HR HR20010527A patent/HRP20010527B1/xx not_active IP Right Cessation
- 2001-08-08 BG BG105795A patent/BG105795A/xx unknown
-
2002
- 2002-04-16 HK HK02102882.5A patent/HK1041006B/zh not_active IP Right Cessation
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