TR200102031T2 - Hücre yapışma önleyicileri olarak monosakkaritlerin türevleri - Google Patents

Hücre yapışma önleyicileri olarak monosakkaritlerin türevleri

Info

Publication number
TR200102031T2
TR200102031T2 TR2001/02031T TR200102031T TR200102031T2 TR 200102031 T2 TR200102031 T2 TR 200102031T2 TR 2001/02031 T TR2001/02031 T TR 2001/02031T TR 200102031 T TR200102031 T TR 200102031T TR 200102031 T2 TR200102031 T2 TR 200102031T2
Authority
TR
Turkey
Prior art keywords
cell adhesion
derivatives
monosaccharides
adhesion inhibitors
inhibitors
Prior art date
Application number
TR2001/02031T
Other languages
English (en)
Inventor
K. Arora Sudershan
P. Tanwar Madan
Bahadur Gupta Jang
Sharma Geeta
Original Assignee
Ranbaxy Laboratories Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Limited filed Critical Ranbaxy Laboratories Limited
Publication of TR200102031T2 publication Critical patent/TR200102031T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Mevcut bulus, daha önceden açiklanmamis, güçlü anti hücre yapismasi ve anti iltihap aktiviteleri sergileyen yeni, ikame edilmis pentoz ve heksoz monosakkarit türevleri grubu ile ilgilidir.Hazirlama yöntemleri,bilesikleri içeren farmasötik kompozisyonlar ve hücre yapismasinin aracilik ettigi kronik iltihapli bozukluklarin tedavi edilmesi,bastirilmasi ve engellenmesi yöntemleri de tarif edilir.
TR2001/02031T 1999-01-12 2000-01-10 Hücre yapışma önleyicileri olarak monosakkaritlerin türevleri TR200102031T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22915599A 1999-01-12 1999-01-12
US09/411,357 US6329344B1 (en) 1998-10-22 1999-10-01 Derivatives of monosaccharides as cell adhesion inhibitors

Publications (1)

Publication Number Publication Date
TR200102031T2 true TR200102031T2 (tr) 2001-12-21

Family

ID=26922990

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/02031T TR200102031T2 (tr) 1999-01-12 2000-01-10 Hücre yapışma önleyicileri olarak monosakkaritlerin türevleri

Country Status (29)

Country Link
US (1) US6329344B1 (tr)
EP (1) EP1144425B1 (tr)
JP (1) JP2002534529A (tr)
CN (1) CN1254478C (tr)
AR (1) AR033939A1 (tr)
AT (1) ATE269349T1 (tr)
AU (1) AU767948B2 (tr)
BG (1) BG105795A (tr)
BR (1) BR0007489A (tr)
CA (1) CA2359980A1 (tr)
CO (1) CO5170511A1 (tr)
CZ (1) CZ20012541A3 (tr)
DE (1) DE60011568T2 (tr)
DK (1) DK1144425T3 (tr)
ES (1) ES2223447T3 (tr)
HK (1) HK1041006B (tr)
HR (1) HRP20010527B1 (tr)
HU (1) HUP0200097A3 (tr)
ID (1) ID30259A (tr)
IL (2) IL144274A0 (tr)
MA (1) MA25679A1 (tr)
MY (1) MY122723A (tr)
NZ (2) NZ512851A (tr)
PA (1) PA8489601A1 (tr)
PT (1) PT1144425E (tr)
SK (1) SK284568B6 (tr)
TR (1) TR200102031T2 (tr)
WO (1) WO2000042053A1 (tr)
YU (1) YU50101A (tr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL152397A (en) * 2002-10-21 2009-02-11 Hadasit Med Res Service Compositions and compounds for the treatment of hyperglycemia
WO2004071515A1 (en) * 2003-02-12 2004-08-26 Ranbaxy Laboratories Limited Preparation of monosaccharide derivatives
WO2004099229A1 (en) * 2003-05-06 2004-11-18 Ranbaxy Laboratories Limited Process for the synthesis of base addition salts of 2,3-0-isopropylidene-1-0-substituted-5,6-dideoxy-5-n- (4-(2-hydroxy-2-oxoethyl)-phenylaminocarbonyl) amino-l-gulofuranosides
NZ543741A (en) 2003-05-30 2009-10-30 Ranbaxy Lab Ltd Substituted pyrrole derivatives and their use as HMG-Co inhibitors
WO2005030735A1 (en) * 2003-09-25 2005-04-07 Ranbaxy Laboratories Limited Triazines derivatives as cell adhesion inhibitors
WO2005092908A1 (en) * 2004-03-18 2005-10-06 Ranbaxy Laboratories Limited Base addition salts of monosaccharides derivatives as inhibitors of airway hyper reactivity and airway inflammation
WO2005092907A2 (en) * 2004-03-26 2005-10-06 Ranbaxy Laboratories Limited Monosaccharide derivatives as anti-cancer and anti-inflammatory agents
WO2005100373A2 (en) * 2004-04-13 2005-10-27 Ranbaxy Laboratories Limited Monosaccharide derivatives as anti-cancer and anti-inflammatory agents
EP1789428A1 (en) * 2004-09-02 2007-05-30 Ranbaxy Laboratories Limited Monosaccharide derivatives
US20100113371A9 (en) * 2004-12-22 2010-05-06 Ranbaxy Laboratories Limited Inc. Derivatives Of Pentose Monosaccharides As Anti-Inflammatory Compounds
US20090054519A1 (en) * 2005-07-22 2009-02-26 Abhijit Ray Derivatives of monosaccharides as 5-lipoxygenase inhibitors
JP2009514851A (ja) 2005-11-08 2009-04-09 ランバクシー ラボラトリーズ リミテッド （３ｒ，５ｒ）−７−［２−（４−フルオロフェニル）−５−イソプロピル−３−フェニル−４−［（４−ヒドロキシメチルフェニルアミノ）カルボニル］−ピロール−１−イル］−３，５−ジヒドロキシ−ヘプタン酸ヘミカルシウム塩の製法
EP1842855A3 (en) * 2006-03-29 2007-12-05 Ranbaxy Laboratories Limited Monosaccharide derivatives as anti-inflammatory and/or anti-cancer agents
EP1864992A2 (en) * 2006-05-30 2007-12-12 Ranbaxy Laboratories, Ltd. Monosaccharide derivatives
US20080300196A1 (en) * 2006-10-03 2008-12-04 Ashwani Kumar Verma Monosaccharide derivatives
CN105367612A (zh) * 2014-08-13 2016-03-02 中国药科大学 龙脷叶由来天然产物丁基2-脱氧-3，6-脱水-β-D-阿拉伯糖呋喃糖苷的全合成方法
US20220356150A1 (en) * 2021-04-30 2022-11-10 Evoco Limited Biobased diisocyanates, and process for preparation of same
WO2024135721A1 (ja) * 2022-12-21 2024-06-27 田辺三菱製薬株式会社 製造中間体の製造方法、その製造中間体及びそれらを用いた架橋型人工核酸中間体の製造方法

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US2715121A (en) 1950-09-09 1955-08-09 American Home Prod Alkyl sugar derivatives and their preparation
US4056322A (en) 1973-12-14 1977-11-01 Strategic Medical Research Corporation Preparation of ethers of monosaccharides
DE2936240A1 (de) * 1979-09-07 1981-03-26 Bayer Ag, 51373 Leverkusen Verfahren zur herstellung bekannter und neuer 6-amino-6-desoxy-2,3-0-isopropyliden-(alpha)-l-sorbofuranose-derivate sowie neue zwischenprodukte des verfahrens
US4735934A (en) 1981-02-17 1988-04-05 Greenwich Pharmaceuticals Incorporated Method of therapeutically treating a warm blooded animal afflicted with an autoimmune disease
US5298494A (en) 1989-01-09 1994-03-29 Greenwich Pharmaceuticals Incorporated Monosaccharides having anti-proliferation and anti-inflammatory activity, compositions and uses thereof
US4996195A (en) 1989-01-09 1991-02-26 Greenwich Pharmaceuticals Inc. Derivatives of α,D-glucofuranose or α,D-allofuranose and intermediates for preparing these derivatives
US5010058A (en) 1989-06-22 1991-04-23 501 Greenwich Pharmaceuticals Incorporated 3,5,6-substituted derivatives of 1,2-O-isopropylidene-α,D-glucofuranose and intermediates for preparing these derivatives
US5192746A (en) 1990-07-09 1993-03-09 Tanabe Seiyaku Co., Ltd. Cyclic cell adhesion modulation compounds
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Also Published As

Publication number Publication date
HK1041006A1 (en) 2002-06-28
ES2223447T3 (es) 2005-03-01
NZ512851A (en) 2004-02-27
SK9962001A3 (en) 2002-02-05
CN1343212A (zh) 2002-04-03
ID30259A (id) 2001-11-15
AU767948B2 (en) 2003-11-27
AR033939A1 (es) 2004-01-21
DK1144425T3 (da) 2004-10-18
BG105795A (en) 2002-05-31
CA2359980A1 (en) 2000-07-20
HUP0200097A2 (hu) 2002-05-29
DE60011568T2 (de) 2005-08-18
CZ20012541A3 (cs) 2002-02-13
HUP0200097A3 (en) 2003-03-28
US6329344B1 (en) 2001-12-11
HRP20010527A2 (en) 2002-08-31
MY122723A (en) 2006-04-29
CO5170511A1 (es) 2002-06-27
JP2002534529A (ja) 2002-10-15
EP1144425B1 (en) 2004-06-16
HK1041006B (zh) 2005-02-04
CN1254478C (zh) 2006-05-03
PT1144425E (pt) 2004-10-29
DE60011568D1 (de) 2004-07-22
YU50101A (sh) 2005-07-19
AU1886000A (en) 2000-08-01
NZ527482A (en) 2005-02-25
EP1144425A1 (en) 2001-10-17
WO2000042053A1 (en) 2000-07-20
BR0007489A (pt) 2002-01-02
IL144274A (en) 2007-05-15
PA8489601A1 (es) 2000-09-29
SK284568B6 (sk) 2005-06-02
MA25679A1 (fr) 2003-04-01
HRP20010527B1 (en) 2005-06-30
IL144274A0 (en) 2002-05-23
ATE269349T1 (de) 2004-07-15

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