EA200200819A1 - Кристаллическая форма ii линезолида - Google Patents

Кристаллическая форма ii линезолида

Info

Publication number
EA200200819A1
EA200200819A1 EA200200819A EA200200819A EA200200819A1 EA 200200819 A1 EA200200819 A1 EA 200200819A1 EA 200200819 A EA200200819 A EA 200200819A EA 200200819 A EA200200819 A EA 200200819A EA 200200819 A1 EA200200819 A1 EA 200200819A1
Authority
EA
Eurasian Patent Office
Prior art keywords
linezolide
crystal form
linezolid
published
useful
Prior art date
Application number
EA200200819A
Other languages
English (en)
Other versions
EA004434B1 (ru
Inventor
Майкл С. Бергрен
Original Assignee
Фармация Энд Апджон Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22658183&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200200819(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Фармация Энд Апджон Компани filed Critical Фармация Энд Апджон Компани
Publication of EA200200819A1 publication Critical patent/EA200200819A1/ru
Publication of EA004434B1 publication Critical patent/EA004434B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/22—Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

Настоящее изобретение относится к новой кристаллической форме (Форма II) известного соединения, линезолида, которое является полезным в качестве антибактериального средства.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200200819A 2000-02-02 2001-01-29 Кристаллическая форма ii линезолида EA004434B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17983700P 2000-02-02 2000-02-02
PCT/US2001/000657 WO2001057035A1 (en) 2000-02-02 2001-01-29 Linezolid-crystal form ii

Publications (2)

Publication Number Publication Date
EA200200819A1 true EA200200819A1 (ru) 2003-02-27
EA004434B1 EA004434B1 (ru) 2004-04-29

Family

ID=22658183

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200819A EA004434B1 (ru) 2000-02-02 2001-01-29 Кристаллическая форма ii линезолида

Country Status (31)

Country Link
EP (1) EP1255754B1 (ru)
JP (1) JP5235256B2 (ru)
KR (3) KR100781815B1 (ru)
CN (1) CN1221547C (ru)
AR (1) AR027261A1 (ru)
AT (1) ATE297920T1 (ru)
AU (1) AU782138B2 (ru)
BR (1) BR0107667A (ru)
CA (1) CA2395603C (ru)
CO (1) CO5261555A1 (ru)
CZ (1) CZ302292B6 (ru)
DE (1) DE60111497T2 (ru)
DK (1) DK1255754T3 (ru)
EA (1) EA004434B1 (ru)
EE (1) EE05197B1 (ru)
ES (1) ES2242728T3 (ru)
HK (1) HK1051196A1 (ru)
HU (1) HUP0301076A3 (ru)
IL (1) IL151010A0 (ru)
MX (1) MXPA02007471A (ru)
MY (1) MY122829A (ru)
NO (2) NO323459B1 (ru)
NZ (1) NZ520541A (ru)
PE (1) PE20011086A1 (ru)
PL (1) PL356433A1 (ru)
PT (1) PT1255754E (ru)
SI (1) SI1255754T1 (ru)
SK (1) SK287025B6 (ru)
TW (1) TWI297687B (ru)
WO (1) WO2001057035A1 (ru)
ZA (1) ZA200205162B (ru)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100490643B1 (ko) * 2002-10-29 2005-05-19 한국과학기술연구원 새로운 메틸리덴 피페리딘일 옥사졸리딘온 유도체 및이들의 제조방법
PT1673370E (pt) 2003-10-16 2009-11-05 Symed Labs Ltd Forma cristalina de linezolida
PL1737850T3 (pl) 2004-04-19 2008-02-29 Symed Labs Ltd Nowy sposób wytwarzania linezolidu i związków pokrewnych
MX2007000084A (es) * 2004-06-29 2007-06-14 Teva Pharma Formas solidas de linezolid y procesos para la preparacion delas mismas.
JP2007504173A (ja) * 2004-06-29 2007-03-01 テバ ファーマシューティカル インダストリーズ リミティド リネゾリドのｉｖ型結晶
EP1866295A2 (en) 2005-02-24 2007-12-19 Teva Pharmaceutical Industries Ltd Processes for the preparation of linezolid intermediate
MX2007002113A (es) * 2005-06-22 2007-04-27 Teva Pharma Formas polimorfas de maleato de tegaserod.
DK1749517T3 (da) * 2005-07-20 2008-11-03 Teva Pharma Stabil farmaceutiske sammensætning af linezolid form IV
WO2007102082A1 (en) * 2006-03-09 2007-09-13 Glenmark Pharmaceuticals Limited High oxazolidinone content solid dosage forms
EP2099299A4 (en) * 2006-10-23 2011-11-30 Concert Pharmaceuticals Inc OXAZOLIDINONE DERIVATIVES AND METHOD FOR THEIR USE
WO2011050826A1 (en) 2009-10-28 2011-05-05 Synthon B.V. Process for making crystalline form a of linezolid
AU2011245302A1 (en) 2010-04-30 2012-11-22 Indiana University Research And Technology Corporation Processes for preparing linezolid
EP2603505A1 (en) 2010-08-11 2013-06-19 Synthon BV Process for making linezolid
EP2690100A1 (en) 2010-08-11 2014-01-29 Synhton B.V. Process for making linezolid
US20140114065A1 (en) * 2011-02-24 2014-04-24 Lee Phama Limited Anhydrous linezolid crystalline form-ii
WO2012119653A1 (en) 2011-03-09 2012-09-13 Synthon Bv Process for making crystalline form a of linezolid
CN102731341A (zh) * 2011-04-13 2012-10-17 上海医药工业研究院 用于制备利奈唑胺的中间体及其制备方法
CN102766106A (zh) * 2011-05-03 2012-11-07 江苏豪森医药集团有限公司 利奈唑胺的新晶型及其制备方法
CN102399200B (zh) * 2011-12-14 2013-12-04 浙江新东港药业股份有限公司 一种利用悬浮结晶法制备利奈唑胺晶型ⅰ的方法
WO2013111048A1 (en) 2012-01-24 2013-08-01 Jubilant Life Sciences Limited Improved process for the preparation of stable crystalline form-i of linezolid, substantially free of residual solvent
WO2013120496A1 (en) 2012-02-14 2013-08-22 Pharmathen S.A. Process for the preparation of linezolid in crystalline form and salts thereof
CN102643245A (zh) * 2012-04-10 2012-08-22 杭州华东医药集团生物工程研究所有限公司 一种利奈唑胺晶型及其制备方法
ES2603252T3 (es) 2012-11-09 2017-02-24 Synthon Bv Proceso para preparar linezolid
CN111432800B (zh) 2017-11-16 2023-12-15 佩尔西卡制药有限公司 利奈唑胺制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
CZ200788A3 (cs) * 1996-04-11 2017-01-25 Pfizer Inc. Způsob přípravy 5-aminomethyl substituovaných oxazolidinonaminů
ES2284216T3 (es) * 1997-11-07 2007-11-01 PHARMACIA & UPJOHN COMPANY LLC Procedeimiento para producir oxazolidinonas.

Also Published As

Publication number Publication date
TWI297687B (en) 2008-06-11
KR100781815B1 (ko) 2007-12-03
JP2003522175A (ja) 2003-07-22
SK9942002A3 (en) 2002-11-06
BR0107667A (pt) 2002-10-08
WO2001057035A1 (en) 2001-08-09
PE20011086A1 (es) 2001-10-04
HUP0301076A2 (hu) 2003-08-28
NO20023654D0 (no) 2002-08-01
KR100864745B1 (ko) 2008-10-22
SI1255754T1 (sl) 2005-12-31
AU3275501A (en) 2001-08-14
DE60111497D1 (de) 2005-07-21
EE05197B1 (et) 2009-08-17
ZA200205162B (en) 2003-09-29
ATE297920T1 (de) 2005-07-15
CO5261555A1 (es) 2003-03-31
CN1221547C (zh) 2005-10-05
CN1394207A (zh) 2003-01-29
IL151010A0 (en) 2003-02-12
EE200200420A (et) 2003-12-15
HK1051196A1 (en) 2003-07-25
SK287025B6 (sk) 2009-10-07
KR20080044358A (ko) 2008-05-20
NZ520541A (en) 2004-02-27
CA2395603A1 (en) 2001-08-09
NO20065836L (no) 2002-08-01
CZ20022635A3 (cs) 2002-10-16
PL356433A1 (en) 2004-06-28
AU782138B2 (en) 2005-07-07
KR20070087178A (ko) 2007-08-27
DK1255754T3 (da) 2005-08-22
ES2242728T3 (es) 2005-11-16
EA004434B1 (ru) 2004-04-29
PT1255754E (pt) 2005-11-30
NO323459B1 (no) 2007-05-14
EP1255754A1 (en) 2002-11-13
CZ302292B6 (cs) 2011-02-09
MY122829A (en) 2006-05-31
CA2395603C (en) 2010-03-23
NO20023654L (no) 2002-08-01
EP1255754B1 (en) 2005-06-15
KR20020072300A (ko) 2002-09-14
MXPA02007471A (es) 2002-12-13
AR027261A1 (es) 2003-03-19
DE60111497T2 (de) 2006-05-18
HUP0301076A3 (en) 2004-06-28
JP5235256B2 (ja) 2013-07-10

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU