DK1385515T3 - Spiropyrazole forbindelser - Google Patents

Spiropyrazole forbindelser

Info

Publication number
DK1385515T3
DK1385515T3 DK02739163T DK02739163T DK1385515T3 DK 1385515 T3 DK1385515 T3 DK 1385515T3 DK 02739163 T DK02739163 T DK 02739163T DK 02739163 T DK02739163 T DK 02739163T DK 1385515 T3 DK1385515 T3 DK 1385515T3
Authority
DK
Denmark
Prior art keywords
spiropyrazole
compounds
spiropyrazole compounds
whereinz
compound
Prior art date
Application number
DK02739163T
Other languages
English (en)
Inventor
Gary Lee
R Richard Goehring
Donald Kyle
Parviz Gharagozloo
Sam Victory
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Application granted granted Critical
Publication of DK1385515T3 publication Critical patent/DK1385515T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Dental Preparations (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DK02739163T 2001-04-18 2002-04-18 Spiropyrazole forbindelser DK1385515T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28467501P 2001-04-18 2001-04-18
PCT/US2002/012376 WO2002085355A1 (en) 2001-04-18 2002-04-18 Spiropyrazole compounds

Publications (1)

Publication Number Publication Date
DK1385515T3 true DK1385515T3 (da) 2008-10-27

Family

ID=23091099

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02739163T DK1385515T3 (da) 2001-04-18 2002-04-18 Spiropyrazole forbindelser

Country Status (28)

Country Link
US (2) US6635653B2 (da)
EP (1) EP1385515B1 (da)
JP (1) JP4342181B2 (da)
KR (1) KR100628292B1 (da)
CN (1) CN1516584A (da)
AT (1) ATE403429T1 (da)
AU (1) AU2002311833B2 (da)
BR (1) BR0209127A (da)
CA (1) CA2444634C (da)
CY (1) CY1108454T1 (da)
CZ (1) CZ20032849A3 (da)
DE (1) DE60228071D1 (da)
DK (1) DK1385515T3 (da)
ES (1) ES2312584T3 (da)
HK (1) HK1062885A1 (da)
HU (1) HUP0401333A3 (da)
IL (2) IL158485A0 (da)
MX (1) MXPA03009604A (da)
NO (1) NO20034660L (da)
NZ (1) NZ528978A (da)
PL (1) PL367263A1 (da)
PT (1) PT1385515E (da)
RU (1) RU2299883C2 (da)
SI (1) SI1385515T1 (da)
UA (1) UA74439C2 (da)
WO (1) WO2002085355A1 (da)
YU (1) YU82403A (da)
ZA (1) ZA200308103B (da)

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US20110092704A1 (en) * 2002-10-17 2011-04-21 Parvis Gharagozloo Preparation of triazospiro compounds
US20040242583A1 (en) * 2003-01-20 2004-12-02 Aventis Pharma Deutschland Gmbh Pyrimido[5,4-e][1,2,4]triazine-5,7-diones, processes for preparing them and their use
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WO2005011665A1 (en) * 2003-07-22 2005-02-10 Arakis Ltd. The use of proglumide for the treatment of emesis
US20100009928A1 (en) 2004-03-29 2010-01-14 Cheng Jin Q Compositions including triciribine and taxanes and methods of use thereof
ES2629682T3 (es) 2004-03-29 2017-08-14 University Of South Florida Tratamiento efectivo de tumores y cáncer con fosfato de triciribina
US20100173864A1 (en) * 2004-03-29 2010-07-08 Cheng Jin Q Compositions including triciribine and one or more platinum compounds and methods of use thereof
US20100028339A1 (en) 2004-03-29 2010-02-04 Cheng Jin Q Compositions including triciribine and trastuzumab and methods of use thereof
US20110008327A1 (en) 2004-03-29 2011-01-13 Cheng Jin Q Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof
US20100009929A1 (en) 2004-03-29 2010-01-14 Cheng Jin Q Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof
EP1858896B1 (en) 2005-03-08 2010-08-18 Janssen Pharmaceutica NV Diaza-spiro-[4.4]-nonane derivatives as neurokinin (nk1) antagonists
CN1870631B (zh) * 2005-11-11 2010-04-14 华为技术有限公司 媒体网关的门控方法
US20080051380A1 (en) 2006-08-25 2008-02-28 Auerbach Alan H Methods and compositions for treating cancer
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KR101227072B1 (ko) * 2007-01-16 2013-01-29 시오노기세이야쿠가부시키가이샤 Ｏｒｌ-1 리간드로서의 헤테로시클릭-치환 피페리딘
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WO2010010458A1 (en) 2008-07-21 2010-01-28 Purdue Pharma L.P. Substituted-quinoxaline-type bridged-piperidine compounds and the uses thereof
UA107943C2 (en) * 2009-11-16 2015-03-10 Lilly Co Eli Compounds of spiropiperidines as antagonists of the orl-1 receptors
EP2654751B1 (en) 2010-12-22 2016-11-23 Purdue Pharma L.P. Phosphorus-substituted quinoxaline-type piperidine compounds and uses thereof
AU2012324015A1 (en) 2011-12-01 2013-06-20 Purdue Pharma L.P. Azetidine-substituted quinoxaline-type piperidine compounds and uses thererof
US9085561B2 (en) 2012-07-30 2015-07-21 Purdue Pharma L.P. Cyclic urea- or lactam-substituted quinoxaline-type piperidines as ORL-1 modulators
US9090618B2 (en) 2012-12-27 2015-07-28 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof
WO2014102592A2 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Oxime/substituted quinoxaline-type piperidine compounds and uses thereof
US10118927B2 (en) 2012-12-27 2018-11-06 Purdue Pharma L.P. Substituted piperidin-4-amino-type compounds and uses thereof
US9951038B2 (en) 2012-12-27 2018-04-24 Purdue Pharma L.P. Quinazolin-4(3H)-one-type piperidine compounds and uses thereof
US9963458B2 (en) 2012-12-27 2018-05-08 Purdue Pharma L.P. Indole and indoline-type piperidine compounds and uses thereof
BR112019001398A2 (pt) 2016-07-29 2019-05-07 Janssen Pharmaceutica Nv métodos para tratamento de câncer de próstata
CN111825681A (zh) * 2020-07-07 2020-10-27 扬州大学 一种合成(e)-亚苄基螺吡唑吡咯嗪酮类化合物的方法

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Also Published As

Publication number Publication date
PL367263A1 (en) 2005-02-21
HUP0401333A2 (hu) 2004-10-28
US6635653B2 (en) 2003-10-21
EP1385515B1 (en) 2008-08-06
ZA200308103B (en) 2004-10-18
NO20034660D0 (no) 2003-10-17
US20040087641A1 (en) 2004-05-06
EP1385515A4 (en) 2004-06-30
SI1385515T1 (sl) 2008-12-31
ATE403429T1 (de) 2008-08-15
US20030027834A1 (en) 2003-02-06
DE60228071D1 (de) 2008-09-18
UA74439C2 (uk) 2005-12-15
IL158485A (en) 2009-09-01
IL158485A0 (en) 2004-05-12
CY1108454T1 (el) 2014-04-09
AU2002311833B2 (en) 2005-04-28
WO2002085355A1 (en) 2002-10-31
RU2299883C2 (ru) 2007-05-27
CZ20032849A3 (en) 2004-03-17
BR0209127A (pt) 2006-03-21
CN1516584A (zh) 2004-07-28
PT1385515E (pt) 2008-09-15
KR20040008159A (ko) 2004-01-28
CA2444634A1 (en) 2002-10-31
RU2003133455A (ru) 2005-05-10
EP1385515A1 (en) 2004-02-04
CA2444634C (en) 2011-06-07
NZ528978A (en) 2004-06-25
KR100628292B1 (ko) 2006-09-27
HUP0401333A3 (en) 2004-11-29
ES2312584T3 (es) 2009-03-01
YU82403A (sh) 2006-08-17
MXPA03009604A (es) 2004-04-02
HK1062885A1 (en) 2004-12-03
JP2004531531A (ja) 2004-10-14
NO20034660L (no) 2003-12-17
JP4342181B2 (ja) 2009-10-14

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