YU82403A - Jedinjenja spiropirazola - Google Patents

Jedinjenja spiropirazola

Info

Publication number
YU82403A
YU82403A YU82403A YUP82403A YU82403A YU 82403 A YU82403 A YU 82403A YU 82403 A YU82403 A YU 82403A YU P82403 A YUP82403 A YU P82403A YU 82403 A YU82403 A YU 82403A
Authority
YU
Yugoslavia
Prior art keywords
spiropyrazole
compounds
spiropyrazole compounds
compound
formula
Prior art date
Application number
YU82403A
Other languages
English (en)
Inventor
R.Richard Goehring
Donald Kyle
Gary Lee
Parviz Gharagozloo
Sam Victory
Original Assignee
Euroceltique S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euroceltique S.A. filed Critical Euroceltique S.A.
Publication of YU82403A publication Critical patent/YU82403A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Dental Preparations (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

Jedinjenje formule (I) gde su Z, W, A, B, C, R1. R2, Q i n definisani u opisu.[A compound of Formula (I) wherein Z, W, A, B, C, R1, R2, Q and n are as disclosed herein.
YU82403A 2001-04-18 2002-04-18 Jedinjenja spiropirazola YU82403A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28467501P 2001-04-18 2001-04-18

Publications (1)

Publication Number Publication Date
YU82403A true YU82403A (sh) 2006-08-17

Family

ID=23091099

Family Applications (1)

Application Number Title Priority Date Filing Date
YU82403A YU82403A (sh) 2001-04-18 2002-04-18 Jedinjenja spiropirazola

Country Status (28)

Country Link
US (2) US6635653B2 (sh)
EP (1) EP1385515B1 (sh)
JP (1) JP4342181B2 (sh)
KR (1) KR100628292B1 (sh)
CN (1) CN1516584A (sh)
AT (1) ATE403429T1 (sh)
AU (1) AU2002311833B2 (sh)
BR (1) BR0209127A (sh)
CA (1) CA2444634C (sh)
CY (1) CY1108454T1 (sh)
CZ (1) CZ20032849A3 (sh)
DE (1) DE60228071D1 (sh)
DK (1) DK1385515T3 (sh)
ES (1) ES2312584T3 (sh)
HK (1) HK1062885A1 (sh)
HU (1) HUP0401333A3 (sh)
IL (2) IL158485A0 (sh)
MX (1) MXPA03009604A (sh)
NO (1) NO20034660L (sh)
NZ (1) NZ528978A (sh)
PL (1) PL367263A1 (sh)
PT (1) PT1385515E (sh)
RU (1) RU2299883C2 (sh)
SI (1) SI1385515T1 (sh)
UA (1) UA74439C2 (sh)
WO (1) WO2002085355A1 (sh)
YU (1) YU82403A (sh)
ZA (1) ZA200308103B (sh)

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JP2006503093A (ja) * 2002-10-17 2006-01-26 ユーロ−セルティーク エス．エイ． トリアゾスピロ化合物の調製
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WO2005011665A1 (en) * 2003-07-22 2005-02-10 Arakis Ltd. The use of proglumide for the treatment of emesis
US20100028339A1 (en) * 2004-03-29 2010-02-04 Cheng Jin Q Compositions including triciribine and trastuzumab and methods of use thereof
US20100009928A1 (en) 2004-03-29 2010-01-14 Cheng Jin Q Compositions including triciribine and taxanes and methods of use thereof
US20100173864A1 (en) 2004-03-29 2010-07-08 Cheng Jin Q Compositions including triciribine and one or more platinum compounds and methods of use thereof
US20100009929A1 (en) 2004-03-29 2010-01-14 Cheng Jin Q Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof
EP1737472B1 (en) 2004-03-29 2014-08-13 University Of South Florida Effective treatment of tumors and cancer with triciribine
US20110008327A1 (en) * 2004-03-29 2011-01-13 Cheng Jin Q Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof
EA014239B1 (ru) 2005-03-08 2010-10-29 Янссен Фармацевтика Н.В. Производные диаза-спиро-[4,4]нонана в качестве антагонистов нейрокинина (nk1)
CN1870631B (zh) * 2005-11-11 2010-04-14 华为技术有限公司 媒体网关的门控方法
US20080051380A1 (en) 2006-08-25 2008-02-28 Auerbach Alan H Methods and compositions for treating cancer
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AR072578A1 (es) 2008-07-21 2010-09-08 Purdue Pharma Lp Compuestos de piperidina puenteada tipo quinoxalina sustituida y los usos de los mismos
UA107943C2 (en) * 2009-11-16 2015-03-10 Lilly Co Eli Compounds of spiropiperidines as antagonists of the orl-1 receptors
JP5872585B2 (ja) 2010-12-22 2016-03-01 パーデュー、ファーマ、リミテッド、パートナーシップ リン置換キノキサリンタイプピペリジン化合物とその使用
JP2014533744A (ja) 2011-12-01 2014-12-15 パーデュー、ファーマ、リミテッド、パートナーシップ アゼチジン置換キノキサリンタイプピペリジン化合物とその使用
US9085561B2 (en) 2012-07-30 2015-07-21 Purdue Pharma L.P. Cyclic urea- or lactam-substituted quinoxaline-type piperidines as ORL-1 modulators
WO2014102589A1 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Quinazolin-4(3h)-one-type piperidine compounds and uses thereof
US10118927B2 (en) 2012-12-27 2018-11-06 Purdue Pharma L.P. Substituted piperidin-4-amino-type compounds and uses thereof
US9090618B2 (en) 2012-12-27 2015-07-28 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof
US9963458B2 (en) 2012-12-27 2018-05-08 Purdue Pharma L.P. Indole and indoline-type piperidine compounds and uses thereof
US9040533B2 (en) 2012-12-27 2015-05-26 Purdue Pharma L.P. Oxime-substituted-quinoxaline-type piperidine compounds as ORL-1 modulators
WO2018023017A1 (en) 2016-07-29 2018-02-01 Janssen Pharmaceutica Nv Methods of treating prostate cancer
CN111825681A (zh) * 2020-07-07 2020-10-27 扬州大学 一种合成(e)-亚苄基螺吡唑吡咯嗪酮类化合物的方法

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Also Published As

Publication number Publication date
UA74439C2 (uk) 2005-12-15
CA2444634C (en) 2011-06-07
CY1108454T1 (el) 2014-04-09
NO20034660D0 (no) 2003-10-17
EP1385515A4 (en) 2004-06-30
CA2444634A1 (en) 2002-10-31
IL158485A (en) 2009-09-01
HUP0401333A3 (en) 2004-11-29
RU2299883C2 (ru) 2007-05-27
IL158485A0 (en) 2004-05-12
WO2002085355A1 (en) 2002-10-31
SI1385515T1 (sl) 2008-12-31
ES2312584T3 (es) 2009-03-01
US6635653B2 (en) 2003-10-21
RU2003133455A (ru) 2005-05-10
US20040087641A1 (en) 2004-05-06
EP1385515B1 (en) 2008-08-06
PL367263A1 (en) 2005-02-21
DE60228071D1 (de) 2008-09-18
HUP0401333A2 (hu) 2004-10-28
DK1385515T3 (da) 2008-10-27
JP4342181B2 (ja) 2009-10-14
NO20034660L (no) 2003-12-17
MXPA03009604A (es) 2004-04-02
KR20040008159A (ko) 2004-01-28
US20030027834A1 (en) 2003-02-06
ATE403429T1 (de) 2008-08-15
NZ528978A (en) 2004-06-25
ZA200308103B (en) 2004-10-18
CZ20032849A3 (en) 2004-03-17
CN1516584A (zh) 2004-07-28
JP2004531531A (ja) 2004-10-14
BR0209127A (pt) 2006-03-21
KR100628292B1 (ko) 2006-09-27
AU2002311833B2 (en) 2005-04-28
HK1062885A1 (en) 2004-12-03
EP1385515A1 (en) 2004-02-04
PT1385515E (pt) 2008-09-15

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