BR112019001398A2 - métodos para tratamento de câncer de próstata - Google Patents

métodos para tratamento de câncer de próstata

Info

Publication number
BR112019001398A2
BR112019001398A2 BR112019001398-9A BR112019001398A BR112019001398A2 BR 112019001398 A2 BR112019001398 A2 BR 112019001398A2 BR 112019001398 A BR112019001398 A BR 112019001398A BR 112019001398 A2 BR112019001398 A2 BR 112019001398A2
Authority
BR
Brazil
Prior art keywords
methods
prostate cancer
cancer treatment
individual
need
Prior art date
Application number
BR112019001398-9A
Other languages
English (en)
Inventor
Gottardis Marco
Hawkins Rebecca
Snyder Linda
H. Yamada Douglas
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of BR112019001398A2 publication Critical patent/BR112019001398A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Urology & Nephrology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

a presente invenção refere-se a métodos para tratamento de câncer de próstata mediante a administração de niraparibe a um indivíduo precisando dos mesmos.
BR112019001398-9A 2016-07-29 2017-07-28 métodos para tratamento de câncer de próstata BR112019001398A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662368466P 2016-07-29 2016-07-29
US62/368,466 2016-07-29
US201662369239P 2016-08-01 2016-08-01
US62/369,239 2016-08-01
PCT/US2017/044413 WO2018023017A1 (en) 2016-07-29 2017-07-28 Methods of treating prostate cancer

Publications (1)

Publication Number Publication Date
BR112019001398A2 true BR112019001398A2 (pt) 2019-05-07

Family

ID=59649991

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019001398-9A BR112019001398A2 (pt) 2016-07-29 2017-07-28 métodos para tratamento de câncer de próstata

Country Status (20)

Country Link
US (8) US20180028521A1 (pt)
EP (1) EP3490560A1 (pt)
JP (2) JP2019522032A (pt)
KR (1) KR20190033599A (pt)
CN (1) CN109640991A (pt)
AU (2) AU2017302660B2 (pt)
BR (1) BR112019001398A2 (pt)
CA (1) CA3031705A1 (pt)
CO (1) CO2019000753A2 (pt)
DO (1) DOP2019000019A (pt)
IL (1) IL264443A (pt)
MA (1) MA45780A (pt)
MX (1) MX2019001224A (pt)
NI (1) NI201900009A (pt)
PE (1) PE20190403A1 (pt)
PH (1) PH12019500135A1 (pt)
SG (1) SG11201900361RA (pt)
SV (1) SV2019005822A (pt)
UA (1) UA124972C2 (pt)
WO (1) WO2018023017A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10865184B2 (en) 2015-04-21 2020-12-15 University Of Tennessee Research Foundation Selective androgen receptor degrader (SARD) ligands and methods of use thereof
US10806720B2 (en) 2015-04-21 2020-10-20 University Of Tennessee Research Foundation Selective androgen receptor degrader (SARD) ligands and methods of use thereof
US10093613B2 (en) 2015-04-21 2018-10-09 Gtx, Inc. Selective androgen receptor degrader (SARD) ligands and methods of use thereof
CA3031705A1 (en) 2016-07-29 2018-02-01 Janssen Pharmaceutica Nv Treatment of prostate cancer with niraparib
TW201929902A (zh) * 2017-12-27 2019-08-01 美商提薩羅有限公司 治療癌症之方法
KR20210120819A (ko) * 2018-05-16 2021-10-07 온크터널 테라퓨틱스 인코포레이티드 선택적 안드로겐 수용체 분해제(sard) 리간드 및 이의 사용 방법
US20210340122A1 (en) * 2018-09-05 2021-11-04 University Of Tennessee Research Foundation Selective androgen receptor degrader (sard) ligands and methods of use thereof
KR20240037954A (ko) * 2021-07-19 2024-03-22 얀센 파마슈티카 엔브이 니라파립을 이용한 전이성 거세-저항성 전립선암의 치료

Family Cites Families (128)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5120722A (en) 1984-02-08 1992-06-09 Hoffmann-La Roche Inc. Trihydroxy-cholecacliferol and trihydroxy-ergocalciferol for treating leukemia
US4857518A (en) 1984-10-04 1989-08-15 Wisconsin Alumni Research Foundation Hydroxylated 24-homo-vitamin D derivatives and methods for preparing same
US4717721A (en) 1985-05-30 1988-01-05 Howard W. Bremer Sidechain homo-vitamin D compounds with preferential anti-cancer activity
JPH07100685B2 (ja) 1985-08-02 1995-11-01 レオ・ファ−マシュ−ティカル・プロダクツ・リミテッド・エイ／エス（レ−ベンス・ケミスケ・ファブリック・プロデュクチオンスアクチ−セルスカブ） 新規ビタミンｄ類似体
US5145846A (en) 1988-01-20 1992-09-08 Hoffmann-La Roche Inc. Vitamin D3 analogs
US4851401A (en) 1988-07-14 1989-07-25 Wisconsin Alumni Research Foundation Novel cyclopentano-vitamin D analogs
CA1333616C (en) 1989-03-09 1994-12-20 Hector F. Deluca 19-nor-vitamin d compounds
GB8915770D0 (en) 1989-07-10 1989-08-31 Leo Pharm Prod Ltd Chemical compounds
US4966898A (en) 1989-08-15 1990-10-30 Merrell Dow Pharmaceuticals Inc. 4-substituted 17β-(cyclopropylamino)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors
DE4021433A1 (de) 1990-07-04 1992-01-09 Schering Ag Antiandrogene mit steroid(3,2-c)pyrazol-struktur
DE4101953A1 (de) 1991-01-19 1992-07-23 Schering Ag 23-oxa-derivate in der vitamin-d-reihe, verfahren zu ihrer herstellung diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel
DE4141746A1 (de) 1991-12-13 1993-06-17 Schering Ag 20-methyl-substituierte vitamin d-derivate
US5604213A (en) 1992-03-31 1997-02-18 British Technology Group Limited 17-substituted steroids useful in cancer treatment
DK0633893T3 (da) 1992-03-31 2000-04-17 Btg Int Ltd 17-Substituerede steroider, der er nyttige ved cancerbehandling
US5547947A (en) 1993-03-11 1996-08-20 Hoffmann-La Roche Inc. Methods of treatment
DK0721461T3 (da) 1993-09-30 1999-09-20 Btg Int Ltd Syntese af 17-(3-pyridyl)-steroider
US5688977A (en) 1996-02-29 1997-11-18 Napro Biotherapeutics, Inc. Method for docetaxel synthesis
ATE196844T1 (de) 1996-05-22 2000-10-15 Protarga Inc Zusammensetzungen die konjugate von cis- docosahexaenoic-säure und taxotere enthalten
US5919815A (en) 1996-05-22 1999-07-06 Neuromedica, Inc. Taxane compounds and compositions
US5795909A (en) 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
GB9622590D0 (en) 1996-10-30 1997-01-08 Leo Pharm Prod Ltd Chemical compounds
US20020128240A1 (en) 1996-12-30 2002-09-12 Bone Care International, Inc. Treatment of hyperproliferative diseases using active vitamin D analogues
US20050233958A1 (en) 1997-03-17 2005-10-20 Human Genome Sciences, Inc. Death domain containing receptor 5
US6872568B1 (en) 1997-03-17 2005-03-29 Human Genome Sciences, Inc. Death domain containing receptor 5 antibodies
US6087350A (en) 1997-08-29 2000-07-11 University Of Pittsburgh Of The Commonwealth System Of Higher Education Use of pretreatment chemicals to enhance efficacy of cytotoxic agents
AU762481C (en) 1998-03-27 2004-08-19 Oregon Health Sciences University Vitamin D and its analogs in the treatment of tumors and other hyperproliferative disorders
US20030083231A1 (en) 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
JP2002533416A (ja) 1998-12-23 2002-10-08 ジー．ディー．サール ＆ カンパニー 新形成の治療における組み合わせ治療としてのシクロオキシゲナーゼ−２インヒビターおよび一つまたはそれ以上の抗腫瘍薬の使用方法
WO2001064251A2 (en) 2000-03-02 2001-09-07 University Of Pittsburgh Of The Commonwealth System Of Higher Education Combination chemotherapy
WO2001081364A1 (fr) 2000-04-24 2001-11-01 Kyowa Hakko Kogyo Co., Ltd. Derives d'estra-1,3,5(10)-triene
AU2001261474B2 (en) 2000-05-15 2006-03-09 Celgene Corporation Compositions and methods for the treatment of cancer
EP1676577A1 (en) 2000-05-15 2006-07-05 Celgene Corporation Compositions for the treatment of cancer comprising a topoisomerase inhibitor and thalidomide
AU7542301A (en) 2000-06-09 2001-12-17 Teni Boulikas Encapsulation of plasmid DNA (lipogenes<sup>TM</sup>) and therapeutic agents with nuclear localization signal/fusogenic peptide conjugates into targeted liposome complexes
AU2000260772A1 (en) 2000-07-05 2002-01-14 Bryan Muehlberger Systems and methods of facilitating electronic payment transactions
US6656942B2 (en) 2000-10-17 2003-12-02 Merck & Co., Inc. Orally active salts with tyrosine kinase activity
US6750213B2 (en) 2000-10-19 2004-06-15 Merck & Co., Inc. Estrogen receptor modulators
DE10061137B4 (de) 2000-12-07 2016-10-06 Takeda Gmbh Neue pharmazeutische Zubereitung
AU2002219472A1 (en) 2001-01-02 2002-07-16 Elisabeth Shanahan-Prendergast Treatment for inhibiting neoplastic lesions using incensole and/or furanogermacrens
WO2002085354A1 (en) 2001-04-18 2002-10-31 Euro-Celtique S.A. Spiroindene and spiroindane compounds
ES2312616T3 (es) 2001-04-18 2009-03-01 Euro-Celtique S.A. Compuestos de bencimidazolona.
US6867222B2 (en) 2001-04-18 2005-03-15 Euro-Celtique, S.A. Nociceptin analogs
ATE403429T1 (de) 2001-04-18 2008-08-15 Euro Celtique Sa Spiropyrazol-verbindungen
CA2445922A1 (en) 2001-05-10 2002-11-21 Merck & Co., Inc. Estrogen receptor modulators
WO2004016753A2 (en) 2002-08-15 2004-02-26 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to trail receptors
WO2002102783A1 (en) 2001-06-19 2002-12-27 Merck & Co., Inc. Tyrosine kinase inhibitors
US6740641B2 (en) 2001-07-27 2004-05-25 Euro-Celtique, S.A. Sugar derivatives of hydromorphone, dihydromorphine and dihydromorphine, compositions thereof and uses for treating or preventing pain
US7186723B2 (en) 2001-08-30 2007-03-06 Merck & Co., Inc. Tyrosine kinase inhibitors
EP1423381B1 (en) 2001-09-06 2007-01-03 Schering Corporation 17beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
WO2003037252A2 (en) 2001-10-30 2003-05-08 Merck & Co., Inc. Tyrosine kinase inhibitors
AU2002363429B2 (en) 2001-11-07 2008-05-08 Merck & Co., Inc. Mitotic kinesin inhibitors
AU2002357053B2 (en) 2001-12-06 2008-05-15 Merck Sharp & Dohme Corp. Mitotic kinesin inhibitors
ES2345044T3 (es) 2002-02-01 2010-09-14 Euro-Celtique S.A. 2-piperazin-piridinas utiles para tratar el dolor.
EP1336602A1 (en) 2002-02-13 2003-08-20 Giovanni Scaramuzzino Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases
US6974818B2 (en) 2002-03-01 2005-12-13 Euro-Celtique S.A. 1,2,5-thiadiazol-3-YL-piperazine therapeutic agents useful for treating pain
US20050159361A1 (en) 2002-03-11 2005-07-21 Takahito Hara Remedies for sex hormone-dependent disease
US7273869B2 (en) 2002-04-08 2007-09-25 Merck & Co., Inc. Inhibitors of Akt activity
EP1927858B1 (en) 2002-04-29 2013-01-09 Euro-Celtique S.A. Conformationally constrained peptides that bind the ORL-1 receptor
US7125888B2 (en) 2002-05-02 2006-10-24 Merck & Co., Inc. Tyrosine kinase inhibitors
EP1515949B1 (en) 2002-06-14 2007-03-14 Merck & Co., Inc. Mitotic kinesin inhibitors
WO2004002983A2 (en) 2002-06-28 2004-01-08 Euro-Celtique, S.A. Therapeutic piperazine derivatives useful for treating pain
US8216609B2 (en) 2002-08-05 2012-07-10 Torrent Pharmaceuticals Limited Modified release composition of highly soluble drugs
US7985422B2 (en) 2002-08-05 2011-07-26 Torrent Pharmaceuticals Limited Dosage form
US8268352B2 (en) 2002-08-05 2012-09-18 Torrent Pharmaceuticals Limited Modified release composition for highly soluble drugs
EP2298315A1 (en) 2002-08-28 2011-03-23 Harbor BioSciences, Inc. Therapeutic treatment methods
US20050101581A1 (en) 2002-08-28 2005-05-12 Reading Christopher L. Therapeutic treatment methods 2
US7157462B2 (en) 2002-09-24 2007-01-02 Euro-Celtique S.A. Therapeutic agents useful for treating pain
US8987240B2 (en) 2002-10-23 2015-03-24 Pantarhei Bioscience B.V. Pharmaceutical compositions comprising estetrol derivatives for use in cancer therapy
CA2503715A1 (en) 2002-10-30 2004-05-21 Merck & Co., Inc. Kinase inhibitors
US7202259B2 (en) 2002-11-18 2007-04-10 Euro-Celtique S.A. Therapeutic agents useful for treating pain
MXPA05006485A (es) 2002-12-17 2005-08-26 Schering Corp Inhibidores de la 17 beta-hidroxiesteroide deshidrogenasa tipo 3 para el tratamiento de enfermedades dependientes de androgeno.
US7582635B2 (en) 2002-12-24 2009-09-01 Purdue Pharma, L.P. Therapeutic agents useful for treating pain
WO2004062620A2 (en) 2003-01-13 2004-07-29 Cedars-Sinai Medical Center Paricalcitol as a chemotherapeutic agent
TWI330079B (en) 2003-01-15 2010-09-11 Synta Pharmaceuticals Corp Treatment for cancers
CA2524737A1 (en) 2003-05-06 2005-02-24 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to trail receptors
US20050020546A1 (en) 2003-06-11 2005-01-27 Novacea, Inc. Pharmaceutical compositions comprising active vitamin D compounds
MY142655A (en) 2003-06-12 2010-12-15 Euro Celtique Sa Therapeutic agents useful for treating pain
EA009480B1 (ru) 2003-07-24 2008-02-28 Еуро-Селтик С. А. Гетероарил-тетрагидропиридины и их применение для лечения или профилактики боли
PL1867644T3 (pl) 2003-07-24 2009-10-30 Euro Celtique Sa Związki heteroarylo-tetrahydropiperydylowe przydatne w leczeniu lub zapobieganiu bólu
US7071333B2 (en) 2003-07-30 2006-07-04 Bristol-Myers Squibb Company Triazolopurine-based tricyclic compounds and pharmaceutical compositions comprising same
DE602004025244D1 (de) 2003-08-01 2010-03-11 Euro Celtique Sa Zur behandlung von schmerzen geeignete therapeutische mittel
CA2535366A1 (en) 2003-08-27 2005-03-10 Merck Frosst Canada & Co. Cathepsin inhibitors
CN1856489A (zh) 2003-09-22 2006-11-01 欧洲凯尔特公司 用于治疗疼痛的苯甲酰胺化合物
DE602004017481D1 (de) 2003-09-22 2008-12-11 Euro Celtique Sa Zur behandlung von schmerzen geeignete therapeutische mittel
ATE369862T1 (de) 2003-10-17 2007-09-15 4 Aza Ip Nv Heterocyclus-substituierte pteridin-derivate und ihre verwendung in der therapie
WO2005107801A2 (en) 2004-04-29 2005-11-17 The Regents Of The University Of Colorado Systems and methods for treating human inflammatory and proliferative diseases, with a combination of fatty acid metabolism inhibitors and glycolytic inhibitors and/or ucp and/or fas antibodies
US20060003950A1 (en) 2004-06-30 2006-01-05 Bone Care International, Inc. Method of treating prostatic diseases using a combination of vitamin D analogues and other agents
US7094775B2 (en) 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
US20060030608A1 (en) 2004-08-04 2006-02-09 Boehringer Ingelheim Pharmaceuticals, Inc. Anti aromatase compounds pharmaceutical compositions and uses thereof
GB0418900D0 (en) 2004-08-24 2004-09-29 Btg Int Ltd Novel salt forms
CA2579732C (en) 2004-09-10 2014-08-12 Nitec Pharma Ag Tablets with site time-controlled gastrointestinal release of active ingredient
AR051597A1 (es) 2004-11-01 2007-01-24 Merck & Co Inc Moduladores de los receptores de estrogeno
EP1674479A1 (en) 2004-12-22 2006-06-28 Memorial Sloan-Kettering Cancer Center Modulation of Fc Gamma receptors for optimizing immunotherapy
WO2006081152A2 (en) 2005-01-24 2006-08-03 Merck & Co., Inc. Estrogen receptor modulators
WO2006116716A2 (en) 2005-04-27 2006-11-02 University Of Florida Materials and methods for enhanced degradation of mutant proteins associated with human disease
JP2008539238A (ja) 2005-04-28 2008-11-13 ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド 治療用二機能性化合物
US7709517B2 (en) 2005-05-13 2010-05-04 The Regents Of The University Of California Diarylhydantoin compounds
CA2616537A1 (en) 2005-07-27 2007-02-01 University Of Florida Research Foundation, Inc. Small compounds that correct protein misfolding and uses thereof
CA2647545C (en) 2006-04-03 2016-02-23 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. Amide substituted indazole and benzotriazole derivatives as poly(adp-ribose)polymerase (parp) inhibitors
EP2035043A2 (en) 2006-06-02 2009-03-18 The Government of the United States of America as Represented by The Department of Health and Human Services Rna nanoparticles and nanotubes
US20080004286A1 (en) 2006-06-30 2008-01-03 Schering Corporation Method of Using Substituted Piperidines that Increase P53 Activity
BRPI0713119A2 (pt) 2006-06-30 2012-04-17 Schering Corp piperidinas substituìdas que aumentam a atividade de p53 e os usos destas
US20080051380A1 (en) 2006-08-25 2008-02-28 Auerbach Alan H Methods and compositions for treating cancer
US20080051375A1 (en) 2006-08-25 2008-02-28 Auerbach Alan H Methods for treating cancer comprising the administration of a vitamin d compound and an additional therapeutic agent, and compositions containing the same
WO2008024484A1 (en) 2006-08-25 2008-02-28 Cougar Biotechnology, Inc. Methods and compositions for treating cancer
EP2081964A4 (en) 2006-10-12 2012-07-11 Univ Johns Hopkins ALGINATE AND ALGINATLYASE COMPOSITIONS AND USE METHOD
US20100168228A1 (en) 2006-10-13 2010-07-01 Reliance Life Sciences Pvt. Ltd. Novel chemotherapeutic agents against inflammation and cancer
SI2805945T1 (sl) 2007-01-10 2019-09-30 Msd Italia S.R.L. Amid substituirani indazoli, kot inhibitorji poli(ADP-riboza)polimeraze(PARP)
EP2491923A3 (en) 2007-02-15 2012-12-26 Novartis AG Combinations of therapeutic agents for treating cancer
WO2008109740A2 (en) 2007-03-06 2008-09-12 Colby Pharmaceutical Company Mitochondria targeted cationic anti-oxidant compounds for prevention, therapy or treatment of hyper-proliferative disease, neoplasias and cancers
WO2009009132A1 (en) 2007-07-12 2009-01-15 Cougar Biotechnology, Inc. Use of 17alpha-hydroxylase/c17, 20-lyase inhibitors for the treatment of cancer
RU2495035C2 (ru) 2008-01-08 2013-10-10 Мерк Шарп Энд Домэ Лтд Фармацевтически приемлемые соли 2-{4-[(3s)-пиперидин-3-ил]фенил}-2н-индазол-7-карбоксамида
CL2009000780A1 (es) 2008-03-31 2010-01-15 Genentech Inc Compuestos derivados de heterociclil-pirano-heterociclilo, heterociclil-oxepina-heterociclilo, benzopirano-heterociclilo y benzoxepina-heterociclilo sustituidos; composicion farmaceutica; procedimiento de preparacion de la composicion; kit farmaceutico; y su uso en el tratamiento del cancer, mediado por la inhibicion de pi3k.
CN104945309B (zh) 2008-05-07 2019-06-04 卡尔迪奥克斯尔制药公司 作为硝酰基供体的新亚硝基化合物及其用途
WO2012009475A1 (en) 2010-07-14 2012-01-19 Oregon Health & Science University Methods of treating cancer with inhibition of lysine-specific demethylase 1
WO2012106514A2 (en) 2011-02-03 2012-08-09 Pop Test Cortisol Llc System and method for diagnosis and treatment
US9314473B2 (en) 2011-02-03 2016-04-19 Pop Test Oncology Limited Liability Company System and method for diagnosis and treatment
WO2014089324A1 (en) 2012-12-07 2014-06-12 Calitor Sciences, Llc Substituted cyclic compounds and methods of use
WO2014150000A1 (en) 2013-03-21 2014-09-25 Isp Investments Inc. Diacetylene film sensitized with photoinitiator and applications of the film
US9192609B2 (en) 2013-04-17 2015-11-24 Hedgepath Pharmaceuticals, Inc. Treatment and prognostic monitoring of proliferation disorders using hedgehog pathway inhibitors
US9987275B2 (en) 2014-04-23 2018-06-05 The Brigham And Women's Hospital, Inc. Targeting PARP1 for treatment of TSC and cancers
US20150344968A1 (en) 2014-05-30 2015-12-03 Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center Methods for determining parp inhibitor and platinum resistance in cancer therapy
EP3230472A4 (en) 2014-12-08 2018-06-13 Myriad Genetics, Inc. Methods and materials for predicting response to niraparib
WO2017023694A1 (en) 2015-08-03 2017-02-09 Pop Test Oncology Llc Pharmaceutical compositions and methods
CA3031705A1 (en) 2016-07-29 2018-02-01 Janssen Pharmaceutica Nv Treatment of prostate cancer with niraparib
WO2018067520A2 (en) 2016-10-04 2018-04-12 Pop Test Oncology Llc Therapeutic agents and methods:
US11702443B2 (en) 2016-10-04 2023-07-18 Pop Test Oncology Llc Therapeutic agents and methods
JOP20190244A1 (ar) 2017-04-13 2019-10-13 Janssen Pharmaceutica Nv تركيبة علاجية لسرطان البروستاتا
BR112020007090A2 (pt) 2017-10-11 2020-09-24 Janssen Oncology, Inc. métodos de tratamento de câncer de próstata mediante a administração de acetato de abiraterona mais prednisona com terapia de supressão androgênica

Also Published As

Publication number Publication date
CA3031705A1 (en) 2018-02-01
PH12019500135A1 (en) 2019-10-28
US20220071979A1 (en) 2022-03-10
US20220071980A1 (en) 2022-03-10
US11986470B2 (en) 2024-05-21
KR20190033599A (ko) 2019-03-29
EP3490560A1 (en) 2019-06-05
US20230098047A1 (en) 2023-03-30
US20240000766A1 (en) 2024-01-04
JP2022122920A (ja) 2022-08-23
PE20190403A1 (es) 2019-03-13
US11986469B2 (en) 2024-05-21
CO2019000753A2 (es) 2019-02-08
US20230078160A1 (en) 2023-03-16
NI201900009A (es) 2019-05-10
AU2017302660A1 (en) 2019-01-24
US20230149380A1 (en) 2023-05-18
US11986468B2 (en) 2024-05-21
MX2019001224A (es) 2019-06-03
AU2023202813A1 (en) 2023-05-25
SV2019005822A (es) 2019-03-28
IL264443A (en) 2019-02-28
MA45780A (fr) 2019-06-05
US11207311B2 (en) 2021-12-28
JP2019522032A (ja) 2019-08-08
CN109640991A (zh) 2019-04-16
WO2018023017A1 (en) 2018-02-01
AU2017302660B2 (en) 2023-04-20
US20180028521A1 (en) 2018-02-01
DOP2019000019A (es) 2019-09-30
US11992486B2 (en) 2024-05-28
UA124972C2 (uk) 2021-12-22
US20190022079A1 (en) 2019-01-24
SG11201900361RA (en) 2019-02-27

Similar Documents

Publication Publication Date Title
BR112019001398A2 (pt) métodos para tratamento de câncer de próstata
CL2018003123A1 (es) Terapia de combinación para el tratamiento del cáncer
EA201591674A1 (ru) Противораковые вакцины и способы лечения с их применением
BR112018010089A2 (pt) composições compreendendo cepas bacterianas
BR112018010464A8 (pt) formulações farmacêuticas tópicas para tratar condições inflamatórias relacionadas
BR112018015836A2 (pt) administração de células t engenheiradas para tratamento de cânceres no sistema nervoso central
BR112018013731A2 (pt) combinações anti-egfr para o tratamento de tumores
BR112018077492A2 (pt) métodos de tratamento de câncer de ovário
BR112017027954A2 (pt) métodos de tratamento de tumores de célula epitelioide
BR112018000776A2 (pt) métodos para tratamento de câncer usando apilimod
BR112017006940A2 (pt) triazolopirazinonas como inibidores de pde1
BR112018013733A2 (pt) combinações anti-cd20 para o tratamento de tumores a
BR112019002331A2 (pt) anticorpos anti-siglec-7 para o tratamento do câncer e métodos para obtenção dos mesmos
EA201891340A1 (ru) Лечение рака с использованием 2-дезокси-2-фтор-l-фукозы в комбинации с ингибитором контрольных точек
KR20180084772A (ko) 암 치료를 위한 조합 치료법
DOP2017000254A (es) Imidazopirazinonas como inhibidores de pde1
BR112018001853A2 (pt) métodos para tratamento de um distúrbio e para melhoria do tratamento de um distúrbio
BR112016017112A2 (pt) Composições de apilimod e métodos de uso das mesmas
EA201991818A1 (ru) Лечение рака
BR112018003526A2 (pt) métodos de tratamento de doenças inflamatórias
PH12017501879A1 (en) Methods for treating cancer
EA201790312A1 (ru) Комбинации лекарственных средств для лечения множественной миеломы
BR112018008882A8 (pt) método para tratar um distúrbio proliferativo e produto farmacêutico
CY1122403T1 (el) Μορφες δοσολογιας και θεραπευτικες χρησεις της l-4-χλωροκυνουρενινης
BR112017009265A2 (pt) apilimode para uso no tratamento do câncer colorretal

Legal Events

Date Code Title Description
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]