EA200200699A1 - Оксазолидиноны, обладающие сульфоксиминовой функциональностью - Google Patents

Оксазолидиноны, обладающие сульфоксиминовой функциональностью

Info

Publication number
EA200200699A1
EA200200699A1 EA200200699A EA200200699A EA200200699A1 EA 200200699 A1 EA200200699 A1 EA 200200699A1 EA 200200699 A EA200200699 A EA 200200699A EA 200200699 A EA200200699 A EA 200200699A EA 200200699 A1 EA200200699 A1 EA 200200699A1
Authority
EA
Eurasian Patent Office
Prior art keywords
sulphoximin
oxazolidinones
functionality
gram
positive
Prior art date
Application number
EA200200699A
Other languages
English (en)
Other versions
EA005567B1 (ru
Inventor
Джексон Б. мл. Хестер
Дэвид Л. Александер
Original Assignee
Фармация Энд Апджон Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фармация Энд Апджон Компани filed Critical Фармация Энд Апджон Компани
Publication of EA200200699A1 publication Critical patent/EA200200699A1/ru
Publication of EA005567B1 publication Critical patent/EA005567B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Данное изобретение представляет соединение формулы Iкоторое обладает высокой активностью против грамположительных и грамотрицательных бактерий.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200200699A 1999-12-21 2000-12-12 Оксазолидиноны, обладающие сульфоксиминовой функциональностью EA005567B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17191699P 1999-12-21 1999-12-21
PCT/US2000/032451 WO2001046185A1 (en) 1999-12-21 2000-12-12 Oxazolidinones having a sulfoximine functionality and their use as antimicrobial agents

Publications (2)

Publication Number Publication Date
EA200200699A1 true EA200200699A1 (ru) 2003-02-27
EA005567B1 EA005567B1 (ru) 2005-04-28

Family

ID=22625632

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200699A EA005567B1 (ru) 1999-12-21 2000-12-12 Оксазолидиноны, обладающие сульфоксиминовой функциональностью

Country Status (22)

Country Link
US (1) US20010046987A1 (ru)
EP (1) EP1242417A1 (ru)
JP (1) JP2003518117A (ru)
KR (1) KR20020067557A (ru)
CN (1) CN1221548C (ru)
AR (1) AR029211A1 (ru)
AU (1) AU782078B2 (ru)
BR (1) BR0016605A (ru)
CA (1) CA2389482A1 (ru)
CO (1) CO5251427A1 (ru)
CZ (1) CZ20022142A3 (ru)
EA (1) EA005567B1 (ru)
HU (1) HUP0203869A2 (ru)
IL (1) IL150348A0 (ru)
MX (1) MXPA02006233A (ru)
NO (1) NO20022973L (ru)
NZ (1) NZ519725A (ru)
PE (1) PE20010931A1 (ru)
PL (1) PL356478A1 (ru)
SK (1) SK7572002A3 (ru)
WO (1) WO2001046185A1 (ru)
ZA (1) ZA200204166B (ru)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
GB0108793D0 (en) * 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compounds
GB0108794D0 (en) * 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compound
GB0108764D0 (en) * 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compounds
ES2268011T3 (es) * 2001-04-07 2007-03-16 Astrazeneca Ab Oxazolidinonas que contienen un grupo sulfonimida como antibioticos.
DE10129725A1 (de) 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
AR038536A1 (es) 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7141588B2 (en) 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
TW200403240A (en) 2002-06-28 2004-03-01 Upjohn Co Difluorothioacetamides of oxazolidinones as antibacterial agents
US6875784B2 (en) 2002-10-09 2005-04-05 Pharmacia & Upjohn Company Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives
DE10300111A1 (de) * 2003-01-07 2004-07-15 Bayer Healthcare Ag Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
CA2521685A1 (en) 2003-04-09 2004-10-21 Pharmacia & Upjohn Company Llc Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues
US7304050B2 (en) 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
US7265140B2 (en) * 2003-09-23 2007-09-04 Pfizer Inc Acyloxymethylcarbamate prodrugs of oxazolidinones
DE10355461A1 (de) 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
CA2589250A1 (en) * 2004-11-29 2006-06-01 Pharmacia & Upjohn Company Llc Diazepine oxazolidinones as antibacterial agents
DE102004062475A1 (de) * 2004-12-24 2006-07-06 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung
EP1685841A1 (en) 2005-01-31 2006-08-02 Bayer Health Care Aktiengesellschaft Prevention and treatment of thromboembolic disorders
ATE449773T1 (de) 2005-06-29 2009-12-15 Pharmacia & Upjohn Co Llc Homomorpholinoxazolidinone als antibakterielle mittel
DE102005045518A1 (de) * 2005-09-23 2007-03-29 Bayer Healthcare Ag 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung
DE102005047558A1 (de) * 2005-10-04 2008-02-07 Bayer Healthcare Ag Kombinationstherapie substituierter Oxazolidinone zur Prophylaxe und Behandlung von cerebralen Durchblutungsstörungen
DE102005047561A1 (de) 2005-10-04 2007-04-05 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
DE502006009169D1 (en) 2005-10-04 2011-05-05 Bayer Schering Pharma Ag NEUE POLYMORPHE FORM VON 5-CHLOR-N-(ä ( 5S )-2-0X0-3-Ä4-( 3-OXO-4-MORPHOLINYL)-PHENYLÜ-1,3-OXAZOLIDIN-5-YLü -METHYL)-2-THIOPHENCARBOXAMID
DE102007028319A1 (de) * 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
WO2021184339A1 (en) * 2020-03-20 2021-09-23 Merck Sharp & Dohme Corp. Oxazolidinone compound and methods of use thereof as an antibacterial agent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
US5952324A (en) * 1994-11-15 1999-09-14 Pharmacia & Upjohn Company Bicyclic oxazine and thiazine oxazolidinone antibacterials
ES2165516T3 (es) * 1995-09-01 2002-03-16 Upjohn Co Feniloxazolidinonas con un enlace c-c con anillos heterociclicos de 4-8 miembros.
US6218413B1 (en) * 1997-05-30 2001-04-17 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality

Also Published As

Publication number Publication date
US20010046987A1 (en) 2001-11-29
CA2389482A1 (en) 2001-06-28
CO5251427A1 (es) 2003-02-28
NO20022973L (no) 2002-08-20
ZA200204166B (en) 2003-10-29
MXPA02006233A (es) 2002-12-05
HUP0203869A2 (hu) 2003-07-28
EA005567B1 (ru) 2005-04-28
CN1391572A (zh) 2003-01-15
BR0016605A (pt) 2003-02-25
AR029211A1 (es) 2003-06-18
NO20022973D0 (no) 2002-06-20
PL356478A1 (en) 2004-06-28
AU782078B2 (en) 2005-06-30
JP2003518117A (ja) 2003-06-03
PE20010931A1 (es) 2001-08-29
SK7572002A3 (en) 2002-12-03
WO2001046185A1 (en) 2001-06-28
NZ519725A (en) 2004-05-28
IL150348A0 (en) 2002-12-01
EP1242417A1 (en) 2002-09-25
CN1221548C (zh) 2005-10-05
AU2050201A (en) 2001-07-03
CZ20022142A3 (cs) 2002-11-13
KR20020067557A (ko) 2002-08-22

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU