AR029211A1 - Derivados de oxazoles, el uso de los mismos para la manufactura de un medicamento y composiciones farmaceuticas que los comprenden - Google Patents

Derivados de oxazoles, el uso de los mismos para la manufactura de un medicamento y composiciones farmaceuticas que los comprenden

Info

Publication number
AR029211A1
AR029211A1 ARP000106795A ARP000106795A AR029211A1 AR 029211 A1 AR029211 A1 AR 029211A1 AR P000106795 A ARP000106795 A AR P000106795A AR P000106795 A ARP000106795 A AR P000106795A AR 029211 A1 AR029211 A1 AR 029211A1
Authority
AR
Argentina
Prior art keywords
manufacture
pharmaceutical compositions
derivatives
oxazoles
understand
Prior art date
Application number
ARP000106795A
Other languages
English (en)
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of AR029211A1 publication Critical patent/AR029211A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Derivados de oxazoles que comprenden compuestos de la formula 1 o una de sus sales farmacéuticamente aceptables y que tienen potente actividad contra las bacterias grampositivas y gramnegativas, en donde: A es una estructura 2, 3, 4 o 5; B es (a) 6; (b) es 7 o (c) es 8; W es NHC(=X) R1 o Y -het, con la condicion de que cuando A es una estructura 5, W no es -Y-het; X es O o S con la condicion de que cuando X es o, B no es la subseccion (b). Y es NH, O o S; Z es S (=O) (=N-R5);Además se describe el uso de las mismas para la manufactura de un medicamento para el tratamiento médico de infecciones microbianas en un mamífero y composiciones farmacéuticas.
ARP000106795A 1999-12-21 2000-12-20 Derivados de oxazoles, el uso de los mismos para la manufactura de un medicamento y composiciones farmaceuticas que los comprenden AR029211A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17191699P 1999-12-21 1999-12-21

Publications (1)

Publication Number Publication Date
AR029211A1 true AR029211A1 (es) 2003-06-18

Family

ID=22625632

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000106795A AR029211A1 (es) 1999-12-21 2000-12-20 Derivados de oxazoles, el uso de los mismos para la manufactura de un medicamento y composiciones farmaceuticas que los comprenden

Country Status (22)

Country Link
US (1) US20010046987A1 (es)
EP (1) EP1242417A1 (es)
JP (1) JP2003518117A (es)
KR (1) KR20020067557A (es)
CN (1) CN1221548C (es)
AR (1) AR029211A1 (es)
AU (1) AU782078B2 (es)
BR (1) BR0016605A (es)
CA (1) CA2389482A1 (es)
CO (1) CO5251427A1 (es)
CZ (1) CZ20022142A3 (es)
EA (1) EA005567B1 (es)
HU (1) HUP0203869A2 (es)
IL (1) IL150348A0 (es)
MX (1) MXPA02006233A (es)
NO (1) NO20022973L (es)
NZ (1) NZ519725A (es)
PE (1) PE20010931A1 (es)
PL (1) PL356478A1 (es)
SK (1) SK7572002A3 (es)
WO (1) WO2001046185A1 (es)
ZA (1) ZA200204166B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
ES2268011T3 (es) * 2001-04-07 2007-03-16 Astrazeneca Ab Oxazolidinonas que contienen un grupo sulfonimida como antibioticos.
GB0108794D0 (en) * 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compound
GB0108793D0 (en) * 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compounds
GB0108764D0 (en) * 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compounds
DE10129725A1 (de) 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
AR038536A1 (es) 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7141588B2 (en) 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
TW200403240A (en) 2002-06-28 2004-03-01 Upjohn Co Difluorothioacetamides of oxazolidinones as antibacterial agents
US6875784B2 (en) 2002-10-09 2005-04-05 Pharmacia & Upjohn Company Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives
DE10300111A1 (de) * 2003-01-07 2004-07-15 Bayer Healthcare Ag Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
WO2004089943A1 (en) 2003-04-09 2004-10-21 Pharmacia & Upjohn Company Llc Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues
US7304050B2 (en) 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
US7265140B2 (en) * 2003-09-23 2007-09-04 Pfizer Inc Acyloxymethylcarbamate prodrugs of oxazolidinones
DE10355461A1 (de) 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
WO2006056877A2 (en) * 2004-11-29 2006-06-01 Pharmacia & Upjohn Company Llc Diazepine oxazolidinones as antibacterial agents
DE102004062475A1 (de) * 2004-12-24 2006-07-06 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung
EP1685841A1 (en) 2005-01-31 2006-08-02 Bayer Health Care Aktiengesellschaft Prevention and treatment of thromboembolic disorders
DE602006010702D1 (de) 2005-06-29 2010-01-07 Pharmacia & Upjohn Co Llc Homomorpholinoxazolidinone als antibakterielle mittel
DE102005045518A1 (de) * 2005-09-23 2007-03-29 Bayer Healthcare Ag 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung
SG166126A1 (en) 2005-10-04 2010-11-29 Bayer Schering Pharma Ag Novel polymorphous form and the amorphous form of 5-chloro-n-({(5s)-2-oxo- 3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide
DE102005047558A1 (de) * 2005-10-04 2008-02-07 Bayer Healthcare Ag Kombinationstherapie substituierter Oxazolidinone zur Prophylaxe und Behandlung von cerebralen Durchblutungsstörungen
DE102005047561A1 (de) 2005-10-04 2007-04-05 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
DE102007028319A1 (de) * 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
WO2021184339A1 (en) * 2020-03-20 2021-09-23 Merck Sharp & Dohme Corp. Oxazolidinone compound and methods of use thereof as an antibacterial agent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
ES2193201T3 (es) * 1994-11-15 2003-11-01 Upjohn Co Agentes antibacterianos tipo oxazolidonas sustituidas con oxazina y tiazina biciclica.
RU2175324C2 (ru) * 1995-09-01 2001-10-27 Фармация Энд Апджон Компани Фенилоксазолидиноны, имеющие с-с-связь с 4-8-членными гетероциклическими кольцами
ATE293609T1 (de) * 1997-05-30 2005-05-15 Upjohn Co Antibakteriell wirksam oxazolidinone mit einer thiocarbonylfunktionalität

Also Published As

Publication number Publication date
KR20020067557A (ko) 2002-08-22
PE20010931A1 (es) 2001-08-29
MXPA02006233A (es) 2002-12-05
EA200200699A1 (ru) 2003-02-27
ZA200204166B (en) 2003-10-29
WO2001046185A1 (en) 2001-06-28
PL356478A1 (en) 2004-06-28
EA005567B1 (ru) 2005-04-28
SK7572002A3 (en) 2002-12-03
IL150348A0 (en) 2002-12-01
CN1391572A (zh) 2003-01-15
NO20022973D0 (no) 2002-06-20
US20010046987A1 (en) 2001-11-29
CA2389482A1 (en) 2001-06-28
JP2003518117A (ja) 2003-06-03
NO20022973L (no) 2002-08-20
HUP0203869A2 (hu) 2003-07-28
CN1221548C (zh) 2005-10-05
AU2050201A (en) 2001-07-03
AU782078B2 (en) 2005-06-30
EP1242417A1 (en) 2002-09-25
NZ519725A (en) 2004-05-28
CO5251427A1 (es) 2003-02-28
BR0016605A (pt) 2003-02-25
CZ20022142A3 (cs) 2002-11-13

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