DE60019919D1 - Hydrochloride kondensierter heterozyklen - Google Patents

Hydrochloride kondensierter heterozyklen

Info

Publication number
DE60019919D1
DE60019919D1 DE60019919T DE60019919T DE60019919D1 DE 60019919 D1 DE60019919 D1 DE 60019919D1 DE 60019919 T DE60019919 T DE 60019919T DE 60019919 T DE60019919 T DE 60019919T DE 60019919 D1 DE60019919 D1 DE 60019919D1
Authority
DE
Germany
Prior art keywords
hydrochloride
condensed heterocycles
heterocycles
condensed
benzylüthiazolid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60019919T
Other languages
English (en)
Other versions
DE60019919T2 (de
Inventor
Takashi Fujita
Toshihiko Fujiwara
Takashi Izumi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=15340495&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60019919(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of DE60019919D1 publication Critical patent/DE60019919D1/de
Application granted granted Critical
Publication of DE60019919T2 publication Critical patent/DE60019919T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DE60019919T 1999-05-24 2000-05-24 Hydrochloride kondensierter heterozyklen Expired - Lifetime DE60019919T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP14351399 1999-05-24
JP14351399 1999-05-24
PCT/JP2000/003325 WO2000071540A1 (fr) 1999-05-24 2000-05-24 Chlorhydrate de compose heterocyclique fusionne

Publications (2)

Publication Number Publication Date
DE60019919D1 true DE60019919D1 (de) 2005-06-09
DE60019919T2 DE60019919T2 (de) 2006-02-16

Family

ID=15340495

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60019919T Expired - Lifetime DE60019919T2 (de) 1999-05-24 2000-05-24 Hydrochloride kondensierter heterozyklen

Country Status (25)

Country Link
US (1) US6706746B2 (de)
EP (1) EP1180519B1 (de)
KR (2) KR100783348B1 (de)
CN (1) CN1156473C (de)
AT (1) ATE294799T1 (de)
AU (1) AU763731B2 (de)
BR (1) BR0010914A (de)
CA (1) CA2375017C (de)
CZ (1) CZ297927B6 (de)
DE (1) DE60019919T2 (de)
DK (1) DK1180519T3 (de)
ES (1) ES2240099T3 (de)
HK (1) HK1042087B (de)
HU (1) HU229340B1 (de)
IL (1) IL146568A0 (de)
MX (1) MXPA01012044A (de)
NO (1) NO321578B1 (de)
NZ (1) NZ515570A (de)
PL (1) PL209389B1 (de)
PT (1) PT1180519E (de)
RU (1) RU2214410C2 (de)
TR (1) TR200103353T2 (de)
TW (1) TWI284533B (de)
WO (1) WO2000071540A1 (de)
ZA (1) ZA200109576B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI284533B (en) * 1999-05-24 2007-08-01 Sankyo Co Pharmaceutical composition for treating hyperglycemia, impaired glucose tolerance, diabetes complications and for improving insulin resistant
EP1695716A2 (de) 2000-12-26 2006-08-30 Sankyo Company, Limited Medizinische Zusammensetzungen enthaltend ein Diuretikum und einen Insulin-Sensibilisator
US6756399B2 (en) * 2001-06-29 2004-06-29 The United States Of America As Represented By The Department Of Health And Human Services Use of lipoxygenase inhibitors and PPAR ligands as anti-cancer therapeutic and intervention agents
WO2003082865A1 (fr) * 2002-04-01 2003-10-09 Sankyo Company, Limited Composition médicinale antitumorale
TW200408628A (en) * 2002-08-02 2004-06-01 Sankyo Co Resorcinol and its derivatives
US6794401B2 (en) * 2003-01-17 2004-09-21 Bexel Pharmaceuticals, Inc. Amino acid phenoxy ethers
US7781464B2 (en) * 2003-01-17 2010-08-24 Bexel Pharmaceuticals, Inc. Heterocyclic diphenyl ethers
US7521465B2 (en) * 2003-01-17 2009-04-21 Bexel Pharmaceuticals, Inc. Diphenyl ether derivatives
US7718377B2 (en) 2003-05-29 2010-05-18 Kyoto Pharmaceutical Industries, Ltd. Insulin resistance curative and method of screening the same
US7087576B2 (en) * 2003-10-07 2006-08-08 Bexel Pharmaceuticals, Inc. Dipeptide phenyl ethers
KR101154175B1 (ko) * 2003-10-24 2012-06-14 산텐 세이야꾸 가부시키가이샤 각결막 장해 치료제
EP1566202A1 (de) * 2004-02-23 2005-08-24 Sahltech I Göteborg AB Verwendung von resistin-antagonisten zur behandlung von Rheumatoider arthritis
CN1972715A (zh) * 2004-03-29 2007-05-30 三共株式会社 含有胰岛素抵抗改善剂的糖尿病治疗剂
TW200608967A (en) 2004-07-29 2006-03-16 Sankyo Co Pharmaceutical compositions containing with diabetic agent
CN101119748A (zh) * 2004-12-13 2008-02-06 第一三共株式会社 用于治疗糖尿病的药物组合物
CA2591416A1 (en) * 2004-12-15 2006-06-22 Daiichi Sankyo Company Limited Medicinal composition containing fbpase inhibitor
TW200637856A (en) * 2005-01-24 2006-11-01 Sankyo Co Process for producing thiazolidinedion compound and intermediate thereof
TW200722088A (en) * 2005-05-27 2007-06-16 Sankyo Co Diabetes remedy
US20080262054A1 (en) * 2005-07-08 2008-10-23 Takao Kawasaki Pharmaceutical Composition Containing Thiazolidinedione Compound
TW200738266A (en) * 2005-09-29 2007-10-16 Sankyo Co Pharmaceutical agent containing insulin resistance improving agent
WO2007061094A1 (ja) 2005-11-28 2007-05-31 Senju Pharmaceutical Co., Ltd. Ｐｐａｒアゴニスト含有医薬
CN101679298B (zh) * 2007-04-05 2013-10-23 第一三共株式会社 稠合二环杂芳基衍生物
JP5247686B2 (ja) 2007-05-21 2013-07-24 千寿製薬株式会社 ＰＰＡＲδアゴニスト含有医薬
US8722710B2 (en) 2007-09-26 2014-05-13 Deuterx, Llc Deuterium-enriched pioglitazone
JPWO2010101164A1 (ja) 2009-03-05 2012-09-10 第一三共株式会社 ピリジン誘導体
AU2014236510A1 (en) 2013-03-14 2015-09-24 Deuterx, Llc Deuterium-enriched 2,4-thiazolidinediones and methods of treatment
ES2831326T3 (es) 2014-01-15 2021-06-08 Poxel Sa Métodos para tratar trastornos neurológicos, metabólicos y otros mediante el uso de pioglitazona enantiopura enriquecida con deuterio
US11767317B1 (en) 2020-06-30 2023-09-26 Poxel Sa Methods of synthesizing enantiopure deuterium-enriched pioglitazone
US11319313B2 (en) 2020-06-30 2022-05-03 Poxel Sa Crystalline forms of deuterium-enriched pioglitazone

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ293016B6 (cs) 1995-06-01 2004-01-14 Sankyo Company Limited Benzimidazolové deriváty a farmaceutické prostředky s jejich obsahem
AU706628B2 (en) 1995-07-03 1999-06-17 Sankyo Company Limited Treatment of arteriosclerosis and xanthoma
TWI284533B (en) * 1999-05-24 2007-08-01 Sankyo Co Pharmaceutical composition for treating hyperglycemia, impaired glucose tolerance, diabetes complications and for improving insulin resistant
EP1197211A4 (de) * 1999-07-19 2004-09-01 Sankyo Co Wirkstoffe zur vorbeugung und behandlung von krebs

Also Published As

Publication number Publication date
NZ515570A (en) 2003-11-28
HU229340B1 (en) 2013-11-28
US6706746B2 (en) 2004-03-16
CA2375017A1 (en) 2000-11-30
HUP0201334A2 (en) 2002-10-28
HUP0201334A3 (en) 2002-11-28
CN1156473C (zh) 2004-07-07
ZA200109576B (en) 2003-02-20
KR100783348B1 (ko) 2007-12-07
PT1180519E (pt) 2005-06-30
TR200103353T2 (tr) 2002-04-22
KR100748053B1 (ko) 2007-08-09
PL351650A1 (en) 2003-05-19
BR0010914A (pt) 2002-02-19
NO321578B1 (no) 2006-06-06
CA2375017C (en) 2009-05-19
HK1042087B (zh) 2005-09-09
NO20015712L (no) 2001-12-20
CZ20014182A3 (cs) 2002-04-17
KR20010113972A (ko) 2001-12-28
HK1042087A1 (en) 2002-08-02
AU763731B2 (en) 2003-07-31
EP1180519A4 (de) 2002-07-10
US20020111373A1 (en) 2002-08-15
RU2214410C2 (ru) 2003-10-20
DE60019919T2 (de) 2006-02-16
TWI284533B (en) 2007-08-01
EP1180519A1 (de) 2002-02-20
DK1180519T3 (da) 2005-06-13
PL209389B1 (pl) 2011-08-31
EP1180519B1 (de) 2005-05-04
AU4948700A (en) 2000-12-12
WO2000071540A1 (fr) 2000-11-30
ES2240099T3 (es) 2005-10-16
IL146568A0 (en) 2002-07-25
MXPA01012044A (es) 2002-05-06
ATE294799T1 (de) 2005-05-15
NO20015712D0 (no) 2001-11-23
CZ297927B6 (cs) 2007-05-02
CN1364168A (zh) 2002-08-14
KR20070034112A (ko) 2007-03-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition