HUP0301076A2 - Linezolid II kristályforma és előállítása - Google Patents

Linezolid II kristályforma és előállítása

Info

Publication number
HUP0301076A2
HUP0301076A2 HU0301076A HUP0301076A HUP0301076A2 HU P0301076 A2 HUP0301076 A2 HU P0301076A2 HU 0301076 A HU0301076 A HU 0301076A HU P0301076 A HUP0301076 A HU P0301076A HU P0301076 A2 HUP0301076 A2 HU P0301076A2
Authority
HU
Hungary
Prior art keywords
linezolid
crystal form
preparation
ezolid
covers
Prior art date
Application number
HU0301076A
Other languages
English (en)
Inventor
Michael S. Bergren
Original Assignee
Pharmacia & Upjohn Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22658183&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0301076(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia & Upjohn Co. filed Critical Pharmacia & Upjohn Co.
Publication of HUP0301076A2 publication Critical patent/HUP0301076A2/hu
Publication of HUP0301076A3 publication Critical patent/HUP0301076A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/22—Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

(57) A találmány az antibakteriális szerként ismert (I) képletű ezolidII kristályformájára vonatkozik. A találmány kiterjed a linezolid IIkristályforma előállítására is. Ó
HU0301076A 2000-02-02 2001-01-29 Linezolid-crystal form ii and preparation thereof HUP0301076A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17983700P 2000-02-02 2000-02-02
PCT/US2001/000657 WO2001057035A1 (en) 2000-02-02 2001-01-29 Linezolid-crystal form ii

Publications (2)

Publication Number Publication Date
HUP0301076A2 true HUP0301076A2 (hu) 2003-08-28
HUP0301076A3 HUP0301076A3 (en) 2004-06-28

Family

ID=22658183

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0301076A HUP0301076A3 (en) 2000-02-02 2001-01-29 Linezolid-crystal form ii and preparation thereof

Country Status (31)

Country Link
EP (1) EP1255754B1 (hu)
JP (1) JP5235256B2 (hu)
KR (3) KR20080044358A (hu)
CN (1) CN1221547C (hu)
AR (1) AR027261A1 (hu)
AT (1) ATE297920T1 (hu)
AU (1) AU782138B2 (hu)
BR (1) BR0107667A (hu)
CA (1) CA2395603C (hu)
CO (1) CO5261555A1 (hu)
CZ (1) CZ302292B6 (hu)
DE (1) DE60111497T2 (hu)
DK (1) DK1255754T3 (hu)
EA (1) EA004434B1 (hu)
EE (1) EE05197B1 (hu)
ES (1) ES2242728T3 (hu)
HK (1) HK1051196A1 (hu)
HU (1) HUP0301076A3 (hu)
IL (1) IL151010A0 (hu)
MX (1) MXPA02007471A (hu)
MY (1) MY122829A (hu)
NO (2) NO323459B1 (hu)
NZ (1) NZ520541A (hu)
PE (1) PE20011086A1 (hu)
PL (1) PL356433A1 (hu)
PT (1) PT1255754E (hu)
SI (1) SI1255754T1 (hu)
SK (1) SK287025B6 (hu)
TW (1) TWI297687B (hu)
WO (1) WO2001057035A1 (hu)
ZA (1) ZA200205162B (hu)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100490643B1 (ko) * 2002-10-29 2005-05-19 한국과학기술연구원 새로운 메틸리덴 피페리딘일 옥사졸리딘온 유도체 및이들의 제조방법
AU2003278592A1 (en) 2003-10-16 2005-04-27 Symed Labs Limited A novel crystalline form of linezolid
US7307163B2 (en) 2004-04-19 2007-12-11 Symed Labs Limited Process for the preparation of linezolid and related compounds
MX2007000084A (es) * 2004-06-29 2007-06-14 Teva Pharma Formas solidas de linezolid y procesos para la preparacion delas mismas.
US20060142283A1 (en) * 2004-06-29 2006-06-29 Judith Aronhime Crystalline form IV of linezolid
US7291614B2 (en) 2005-02-24 2007-11-06 Teva Pharmaceutical Industries Ltd. Processes for the preparation of linezolid intermediate
EP1893195A2 (en) * 2005-06-22 2008-03-05 Teva Pharmaceutical Industries Ltd Polymorphic forms of tegaserod maleate
ATE400257T1 (de) * 2005-07-20 2008-07-15 Teva Pharma Stabile pharmazeutische zusammensetzung mit linezolid form iv
WO2007102082A1 (en) * 2006-03-09 2007-09-13 Glenmark Pharmaceuticals Limited High oxazolidinone content solid dosage forms
EP2099299A4 (en) * 2006-10-23 2011-11-30 Concert Pharmaceuticals Inc OXAZOLIDINONE DERIVATIVES AND METHOD FOR THEIR USE
WO2011050826A1 (en) 2009-10-28 2011-05-05 Synthon B.V. Process for making crystalline form a of linezolid
RU2012151303A (ru) 2010-04-30 2014-06-10 Индиана Юниверсити Рисерч Эдн Текнолоджи Корпорейшн Способы получения линезолида
EP2603506A1 (en) 2010-08-11 2013-06-19 Synthon BV Process for making linezolid
WO2012019632A1 (en) 2010-08-11 2012-02-16 Synthon B.V. Process for making linezolid
EP2593440A1 (en) * 2011-02-24 2013-05-22 Lee Pharma Limited Anhydrous linezolid crystalline form-ii
WO2012119653A1 (en) 2011-03-09 2012-09-13 Synthon Bv Process for making crystalline form a of linezolid
CN102731341A (zh) * 2011-04-13 2012-10-17 上海医药工业研究院 用于制备利奈唑胺的中间体及其制备方法
CN105461648B (zh) * 2011-05-03 2018-01-12 江苏豪森药业集团有限公司 利奈唑胺的晶型及其制备方法
CN102399200B (zh) * 2011-12-14 2013-12-04 浙江新东港药业股份有限公司 一种利用悬浮结晶法制备利奈唑胺晶型ⅰ的方法
IN2014DN06213A (hu) 2012-01-24 2015-10-23 Jubilant Life Sciences Ltd
WO2013120496A1 (en) 2012-02-14 2013-08-22 Pharmathen S.A. Process for the preparation of linezolid in crystalline form and salts thereof
CN102643245A (zh) * 2012-04-10 2012-08-22 杭州华东医药集团生物工程研究所有限公司 一种利奈唑胺晶型及其制备方法
ES2603252T3 (es) 2012-11-09 2017-02-24 Synthon Bv Proceso para preparar linezolid
SG11202003537TA (en) 2017-11-16 2020-05-28 Persica Pharmaceuticals Ltd Linezolid formulations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
RU2176643C2 (ru) * 1996-04-11 2001-12-10 Фармация Энд Апджон Компани Способ получения 5-гидроксиметил замещенных оксазолидинонов, способ получения 5-аминометил замещенных оксазолидиноновых аминов, оксазолидинонсульфонат
US6107519A (en) * 1997-11-07 2000-08-22 Pharmacia & Upjohn Company Process to produce oxazolidinones

Also Published As

Publication number Publication date
JP2003522175A (ja) 2003-07-22
AU3275501A (en) 2001-08-14
CO5261555A1 (es) 2003-03-31
NO323459B1 (no) 2007-05-14
KR20020072300A (ko) 2002-09-14
NZ520541A (en) 2004-02-27
CZ302292B6 (cs) 2011-02-09
EA200200819A1 (ru) 2003-02-27
KR100864745B1 (ko) 2008-10-22
CA2395603A1 (en) 2001-08-09
CA2395603C (en) 2010-03-23
TWI297687B (en) 2008-06-11
NO20023654D0 (no) 2002-08-01
MY122829A (en) 2006-05-31
ZA200205162B (en) 2003-09-29
EE200200420A (et) 2003-12-15
AR027261A1 (es) 2003-03-19
CN1221547C (zh) 2005-10-05
JP5235256B2 (ja) 2013-07-10
SK287025B6 (sk) 2009-10-07
HUP0301076A3 (en) 2004-06-28
WO2001057035A1 (en) 2001-08-09
NO20065836L (no) 2002-08-01
CN1394207A (zh) 2003-01-29
KR100781815B1 (ko) 2007-12-03
AU782138B2 (en) 2005-07-07
PE20011086A1 (es) 2001-10-04
IL151010A0 (en) 2003-02-12
MXPA02007471A (es) 2002-12-13
NO20023654L (no) 2002-08-01
CZ20022635A3 (cs) 2002-10-16
EA004434B1 (ru) 2004-04-29
SK9942002A3 (en) 2002-11-06
KR20070087178A (ko) 2007-08-27
PT1255754E (pt) 2005-11-30
ES2242728T3 (es) 2005-11-16
DK1255754T3 (da) 2005-08-22
DE60111497D1 (de) 2005-07-21
BR0107667A (pt) 2002-10-08
DE60111497T2 (de) 2006-05-18
EP1255754A1 (en) 2002-11-13
EE05197B1 (et) 2009-08-17
PL356433A1 (en) 2004-06-28
HK1051196A1 (en) 2003-07-25
EP1255754B1 (en) 2005-06-15
ATE297920T1 (de) 2005-07-15
KR20080044358A (ko) 2008-05-20
SI1255754T1 (sl) 2005-12-31

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees