PL392652A1 - Kombinacja zawierająca N-{5-[4-(4-metylo-piperazyno-metylo)-benzoiloamido]-2-metylofenylo}-4-(3-pirydylo)-2-pirymidyno-aminę oraz środek chemoterapeutyczny, jej zastosowanie, kompozycja farmaceutyczna ją zawierająca oraz zestaw zawierający taką kombinację - Google Patents

Kombinacja zawierająca N-{5-[4-(4-metylo-piperazyno-metylo)-benzoiloamido]-2-metylofenylo}-4-(3-pirydylo)-2-pirymidyno-aminę oraz środek chemoterapeutyczny, jej zastosowanie, kompozycja farmaceutyczna ją zawierająca oraz zestaw zawierający taką kombinację

Info

Publication number
PL392652A1
PL392652A1 PL392652A PL39265202A PL392652A1 PL 392652 A1 PL392652 A1 PL 392652A1 PL 392652 A PL392652 A PL 392652A PL 39265202 A PL39265202 A PL 39265202A PL 392652 A1 PL392652 A1 PL 392652A1
Authority
PL
Poland
Prior art keywords
methyl
combination
methylphenyl
pyrimidine
pyridyl
Prior art date
Application number
PL392652A
Other languages
English (en)
Inventor
Christian Bruns
Elisabeth Buchdunger
Terrence O'reilly
Sandra Leta Silberman
Markus Wartmann
Gisbert Weckbecker
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL392652A1 publication Critical patent/PL392652A1/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
PL392652A 2001-05-16 2002-05-15 Kombinacja zawierająca N-{5-[4-(4-metylo-piperazyno-metylo)-benzoiloamido]-2-metylofenylo}-4-(3-pirydylo)-2-pirymidyno-aminę oraz środek chemoterapeutyczny, jej zastosowanie, kompozycja farmaceutyczna ją zawierająca oraz zestaw zawierający taką kombinację PL392652A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29142701P 2001-05-16 2001-05-16

Publications (1)

Publication Number Publication Date
PL392652A1 true PL392652A1 (pl) 2010-12-06

Family

ID=23120246

Family Applications (2)

Application Number Title Priority Date Filing Date
PL392652A PL392652A1 (pl) 2001-05-16 2002-05-15 Kombinacja zawierająca N-{5-[4-(4-metylo-piperazyno-metylo)-benzoiloamido]-2-metylofenylo}-4-(3-pirydylo)-2-pirymidyno-aminę oraz środek chemoterapeutyczny, jej zastosowanie, kompozycja farmaceutyczna ją zawierająca oraz zestaw zawierający taką kombinację
PL02368068A PL368068A1 (pl) 2001-05-16 2002-05-15 Kombinacja lekowa zawierająca N-{5-[4-(4-metylo-piperazyno-metylo)-benzoiloamido]-2-metylofenylo}-4-(3-pirydylo)-2-pirymidyno-aminę oraz środek chemoterapeutyczny

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL02368068A PL368068A1 (pl) 2001-05-16 2002-05-15 Kombinacja lekowa zawierająca N-{5-[4-(4-metylo-piperazyno-metylo)-benzoiloamido]-2-metylofenylo}-4-(3-pirydylo)-2-pirymidyno-aminę oraz środek chemoterapeutyczny

Country Status (27)

Country Link
US (3) US20040167134A1 (pl)
EP (2) EP1392313B1 (pl)
JP (2) JP4477303B2 (pl)
KR (2) KR20080091866A (pl)
CN (1) CN1700917B (pl)
AT (1) ATE359790T1 (pl)
AU (1) AU2002342335B2 (pl)
BR (1) BR0209647A (pl)
CA (1) CA2444867C (pl)
CO (1) CO5540315A2 (pl)
CZ (1) CZ299756B6 (pl)
DE (1) DE60219617T2 (pl)
DK (1) DK1392313T3 (pl)
EC (1) ECSP034823A (pl)
ES (1) ES2283570T3 (pl)
HU (1) HUP0400038A3 (pl)
IL (1) IL158274A0 (pl)
MX (1) MXPA03010401A (pl)
NO (2) NO325453B1 (pl)
NZ (1) NZ529145A (pl)
PL (2) PL392652A1 (pl)
PT (1) PT1392313E (pl)
RU (1) RU2318517C2 (pl)
SI (1) SI1392313T1 (pl)
SK (1) SK14042003A3 (pl)
WO (1) WO2002092091A1 (pl)
ZA (1) ZA200307665B (pl)

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US8962650B2 (en) 2011-04-18 2015-02-24 Eisai R&D Management Co., Ltd. Therapeutic agent for tumor
JP6038128B2 (ja) 2011-06-03 2016-12-07 エーザイ・アール・アンド・ディー・マネジメント株式会社 レンバチニブ化合物に対する甲状腺癌対象及び腎臓癌対象の反応性を予測及び評価するためのバイオマーカー
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Also Published As

Publication number Publication date
ZA200307665B (en) 2004-04-21
CZ20033098A3 (cs) 2004-02-18
RU2003135786A (ru) 2005-02-27
NO20034713D0 (no) 2003-10-21
NZ529145A (en) 2005-07-29
JP2010059202A (ja) 2010-03-18
KR20030094415A (ko) 2003-12-11
RU2318517C2 (ru) 2008-03-10
MXPA03010401A (es) 2004-03-09
SI1392313T1 (sl) 2007-08-31
JP4477303B2 (ja) 2010-06-09
AU2002342335B2 (en) 2006-02-02
SK14042003A3 (sk) 2004-05-04
JP2004531549A (ja) 2004-10-14
DK1392313T3 (da) 2007-06-25
CN1700917B (zh) 2010-04-28
NO20076323L (no) 2007-12-07
HK1062895A1 (en) 2004-12-03
NO325453B1 (no) 2008-05-05
PT1392313E (pt) 2007-07-17
HUP0400038A2 (hu) 2004-04-28
US20090202541A1 (en) 2009-08-13
CZ299756B6 (cs) 2008-11-12
US20040167134A1 (en) 2004-08-26
NO20034713L (no) 2003-10-21
EP1392313B1 (en) 2007-04-18
HUP0400038A3 (en) 2007-05-29
ATE359790T1 (de) 2007-05-15
DE60219617D1 (de) 2007-05-31
ES2283570T3 (es) 2007-11-01
PL368068A1 (pl) 2005-03-21
BR0209647A (pt) 2004-07-27
WO2002092091A1 (en) 2002-11-21
US20120283206A1 (en) 2012-11-08
IL158274A0 (en) 2004-05-12
CA2444867C (en) 2010-08-17
EP2253319A1 (en) 2010-11-24
CO5540315A2 (es) 2005-07-29
EP1392313A1 (en) 2004-03-03
CA2444867A1 (en) 2002-11-21
CN1700917A (zh) 2005-11-23
ECSP034823A (es) 2003-12-24
DE60219617T2 (de) 2008-01-03
KR20080091866A (ko) 2008-10-14

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