PL365677A1 - Urządzenie do przezskórnego dostarczania leku posiadające powlekane mikrowystępy - Google Patents

Urządzenie do przezskórnego dostarczania leku posiadające powlekane mikrowystępy

Info

Publication number
PL365677A1
PL365677A1 PL01365677A PL36567701A PL365677A1 PL 365677 A1 PL365677 A1 PL 365677A1 PL 01365677 A PL01365677 A PL 01365677A PL 36567701 A PL36567701 A PL 36567701A PL 365677 A1 PL365677 A1 PL 365677A1
Authority
PL
Poland
Prior art keywords
drug delivery
delivery devices
transdermal drug
pharmacologically active
active agent
Prior art date
Application number
PL01365677A
Other languages
English (en)
Inventor
Michel J.N. Cormier
Wendy A. Young
Kofi Nyam
Peter E. Daddona
Original Assignee
Alza Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corporation filed Critical Alza Corporation
Publication of PL365677A1 publication Critical patent/PL365677A1/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061—Methods for using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
PL01365677A 2000-10-26 2001-10-26 Urządzenie do przezskórnego dostarczania leku posiadające powlekane mikrowystępy PL365677A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24403800P 2000-10-26 2000-10-26

Publications (1)

Publication Number Publication Date
PL365677A1 true PL365677A1 (pl) 2005-01-10

Family

ID=22921144

Family Applications (1)

Application Number Title Priority Date Filing Date
PL01365677A PL365677A1 (pl) 2000-10-26 2001-10-26 Urządzenie do przezskórnego dostarczania leku posiadające powlekane mikrowystępy

Country Status (24)

Country Link
US (2) US7537795B2 (pl)
EP (2) EP1333880B1 (pl)
JP (2) JP4659336B2 (pl)
KR (1) KR100812097B1 (pl)
CN (1) CN1239212C (pl)
AT (1) ATE428466T1 (pl)
AU (1) AU2001297823B2 (pl)
BR (1) BR0114909A (pl)
CA (1) CA2427381A1 (pl)
CZ (1) CZ20031164A3 (pl)
DE (1) DE60138407D1 (pl)
DK (1) DK1333880T3 (pl)
ES (1) ES2322023T3 (pl)
HU (1) HUP0302924A2 (pl)
IL (1) IL155583A0 (pl)
MA (1) MA26061A1 (pl)
MX (1) MXPA03003815A (pl)
NO (1) NO20031875L (pl)
NZ (1) NZ525551A (pl)
PL (1) PL365677A1 (pl)
PT (1) PT1333880E (pl)
RU (1) RU2282468C2 (pl)
WO (1) WO2002094368A1 (pl)
ZA (1) ZA200303988B (pl)

Families Citing this family (149)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA975326B (en) * 1996-06-18 1998-01-14 Alza Corp Device and method for enhancing transdermal flux of agents being delivered or sampled.
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
AU8877401A (en) * 2000-09-08 2002-03-22 Alza Corp Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure
AU9682801A (en) * 2000-10-13 2002-04-22 Alza Corp Apparatus and method for piercing skin with microprotrusions
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
HUP0303576A2 (en) * 2000-10-13 2004-01-28 Alza Corp Microprotrusion member retainer for impact applicator
US6855372B2 (en) * 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
CN100349632C (zh) * 2001-04-20 2007-11-21 阿尔扎公司 具有包含有益药剂的涂层的微小突出物阵列
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
US20030199810A1 (en) * 2001-11-30 2003-10-23 Trautman Joseph Creagan Methods and apparatuses for forming microprojection arrays
HUP0402605A2 (hu) * 2001-12-20 2005-06-28 Alza Corporation Eszköz mikroszkopikus bemetszések ejtésére állat bőrszövetén
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
GB0210397D0 (en) * 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
AR040819A1 (es) * 2002-08-08 2005-04-20 Alza Corp Dispositivo de administracion transdermica de vacuna que tiene microproyecciones revestidas
AU2003275301A1 (en) * 2002-09-30 2004-04-23 Alza Corporation Drug delivery device having coated microprojections incorporating vasoconstrictors
AR042815A1 (es) * 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
AU2004255228A1 (en) * 2003-06-30 2005-01-20 Alza Corporation Method for coating skin piercing microprojections
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
EP1638523B8 (en) 2003-06-30 2013-12-25 ALZA Corporation Formulations for coated microprojections containing non-volatile counterions
UY28398A1 (es) * 2003-07-02 2004-11-08 Alza Corp Método y parche de inmunización por disposición de microproyección
TW200514596A (en) * 2003-08-04 2005-05-01 Alza Corp Method and device for enhancing transdermal agent flux
JP2007503268A (ja) 2003-08-25 2007-02-22 スリーエム イノベイティブ プロパティズ カンパニー 免疫応答修飾化合物の送達
CN1842355A (zh) * 2003-08-26 2006-10-04 阿尔扎公司 用于皮内细胞植入的装置和方法
CA2542874A1 (en) * 2003-10-23 2005-05-12 Alza Corporation Compositions of stabilized dna for coating microprojections
BRPI0415466A (pt) 2003-10-24 2006-12-19 Alza Corp método e sistema de pré-tratamento para intensificar a distribuição transdérmica de fármacos
AU2004285481A1 (en) * 2003-10-24 2005-05-12 Alza Corporation Apparatus and method for enhancing transdermal drug delivery
CN1897882A (zh) 2003-10-28 2007-01-17 阿尔扎公司 降低烟草使用频率的方法和装置
JP4682144B2 (ja) * 2003-10-31 2011-05-11 アルザ・コーポレーシヨン 微小突起列のための自己−作動性アプリケーター
WO2005051456A2 (en) * 2003-11-13 2005-06-09 Alza Corporation Composition and apparatus for transdermal delivery
DE10353629A1 (de) * 2003-11-17 2005-06-16 Lts Lohmann Therapie-Systeme Ag Vorrichtung zur transdermalen Verabreichung von Wirkstoffen
US20080226699A1 (en) * 2003-11-28 2008-09-18 Acrux Dds Pty Ltd Method and System for Rapid Transdermal Administration
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
WO2005075016A1 (ja) * 2004-02-03 2005-08-18 Hisamitsu Pharmaceutical Co., Inc. 経皮薬物投与装置用インタフェース
CA2562932A1 (en) 2004-04-01 2005-10-27 Alza Corporation Apparatus and method for transdermal delivery of influenza vaccine
AU2005235990A1 (en) * 2004-04-13 2005-11-03 Alza Corporation Apparatus and method for transdermal delivery of multiple vaccines
JP5007427B2 (ja) * 2004-05-13 2012-08-22 アルザ コーポレイション 副甲状腺ホルモン剤の経皮送達のための装置および方法
CA2566759A1 (en) * 2004-05-19 2005-11-24 Alza Corporation Method and formulation for transdermal delivery of immunologically active agents
US20060030811A1 (en) * 2004-08-03 2006-02-09 Wong Patrick S Method and device for enhancing transdermal agent flux
US20060100584A1 (en) * 2004-08-10 2006-05-11 Orest Olejnik Needleless microprotrusion elastoplast system
AR050608A1 (es) * 2004-08-19 2006-11-08 Alza Corp Aparato y metodo para administracion transdermica de factores de crecimiento endotelial vascular
AR054309A1 (es) * 2004-09-08 2007-06-20 Alza Corp Disposicion de microproyecciones con mejor adhesion cutanea y distensibilidad
WO2006047198A2 (en) * 2004-10-26 2006-05-04 Caritas St. Elizabeth Medical Center Of Boston, Inc. Composition and method for using a cytokine to treat restenosis
US20060093658A1 (en) * 2004-10-26 2006-05-04 Gayatri Sathyan Apparatus and method for transdermal delivery of desmopressin
WO2006055844A2 (en) 2004-11-18 2006-05-26 3M Innovative Properties Company Method of contact coating a microneedle array
CN101060883B (zh) 2004-11-18 2010-06-23 3M创新有限公司 低轮廓微针阵列施放器
US8057842B2 (en) * 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
AU2005306426B2 (en) * 2004-11-18 2011-04-28 3M Innovative Properties Company Masking method for coating a microneedle array
JP5882556B2 (ja) * 2004-12-28 2016-03-09 ナブテスコ株式会社 皮膚用針、皮膚用針製造装置および皮膚用針製造方法
CA2593112A1 (en) * 2005-01-21 2006-07-27 Alza Corporation Therapeutic peptide formulations for coating microneedles with improved stability containing at least one counterion
CN101160117A (zh) * 2005-02-16 2008-04-09 阿尔扎公司 依泊汀-基药物的透皮释放装置和方法
US20060204562A1 (en) * 2005-02-16 2006-09-14 Cormier Michel J Microprojection arrays with improved biocompatibility
AU2006230308A1 (en) * 2005-03-28 2006-10-05 Alza Corporation Microprojections with capillary control features and method
US20080009802A1 (en) * 2005-04-25 2008-01-10 Danilo Lambino Method of treating acne with stratum corneum piercing device
US20070270738A1 (en) * 2005-04-25 2007-11-22 Wu Jeffrey M Method of treating ACNE with stratum corneum piercing patch
US20060253078A1 (en) * 2005-04-25 2006-11-09 Wu Jeffrey M Method of treating skin disorders with stratum corneum piercing device
WO2006130869A1 (en) * 2005-06-02 2006-12-07 Alza Corporation Method for terminal sterilization of transdermal delivery devices
WO2006130826A1 (en) * 2005-06-02 2006-12-07 Alza Corporation Method for terminal sterilization of transdermal delivery devices
WO2007002523A2 (en) * 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
US20070078414A1 (en) * 2005-08-05 2007-04-05 Mcallister Devin V Methods and devices for delivering agents across biological barriers
EP1922364A4 (en) 2005-08-09 2010-04-21 Univ North Carolina METHODS AND MATERIALS FOR MANUFACTURING MICROFLUIDIC DEVICES
CA2620943A1 (en) * 2005-09-02 2007-03-08 Iomai Corporation Devices for transcutaneous delivery of vaccines and transdermal delivery of drugs and uses thereof
EP1924364A1 (en) * 2005-09-12 2008-05-28 Alza Corporation Coatable transdermal delivery microprojection assembly
EP1948139A4 (en) * 2005-11-18 2012-04-04 3M Innovative Properties Co COATING COMPOSITIONS, COATINGS DERIVED THEREFROM, AND MICRO-NETWORKS COMPRISING SUCH COATINGS
EP1957145A4 (en) * 2005-11-30 2011-03-23 3M Innovative Properties Co MICRONADEL ASSEMBLIES AND APPLICATION METHOD
EP1962942A1 (en) * 2005-12-21 2008-09-03 3M Innovative Properties Company Microneedle devices
US8632801B2 (en) * 2005-12-28 2014-01-21 Alza Corporation Stable therapeutic formulations
WO2007081876A2 (en) 2006-01-04 2007-07-19 Liquidia Technologies, Inc. Nanostructured surfaces for biomedical/biomaterial applications and processes thereof
EP2001453A4 (en) * 2006-03-15 2012-09-12 Alza Corp APPARATUS AND METHOD FOR TRANSDERMAL DELIVERY OF PARATHYROID HORMONE AGENTS FOR TREATING OR PREVENTING OSTEOPENIA
US20070224252A1 (en) * 2006-03-27 2007-09-27 Trautman Joseph C Microprojections with capillary control features and method
WO2007124411A1 (en) * 2006-04-20 2007-11-01 3M Innovative Properties Company Device for applying a microneedle array
WO2007127815A2 (en) * 2006-04-25 2007-11-08 Alza Corporation Microprojection array application with multilayered microprojection member for high drug loading
US20070293816A1 (en) * 2006-04-25 2007-12-20 Alza Corporation Microprojection Array Application with Grouped Microprojections for High Drug Loading
JP4821993B2 (ja) * 2006-07-21 2011-11-24 芳一 飛永 マイクロインプリメント及びその製造方法
US9114238B2 (en) 2007-04-16 2015-08-25 Corium International, Inc. Solvent-cast microprotrusion arrays containing active ingredient
EP2153863B1 (en) 2007-05-15 2022-03-16 Hisamitsu Pharmaceutical Co., Inc. Method of coating microneedle
US20100137429A1 (en) * 2007-06-21 2010-06-03 Fujimoto Co., Ltd. Composition for transdermal or transmucosal administration
CA2988753A1 (en) 2007-08-06 2009-02-12 Serenity Pharmaceuticals, Llc Methods and devices for desmopressin drug delivery
EP2205169B1 (en) * 2007-09-28 2016-11-16 The Queen's University of Belfast Delivery device and method
US20090105673A1 (en) * 2007-10-17 2009-04-23 Cascio Gregory R Medicament applicator
US7806878B2 (en) * 2007-10-17 2010-10-05 Cascio Gregory R Medicament applicator
JP5538897B2 (ja) * 2007-11-21 2014-07-02 株式会社バイオセレンタック 体表適用製剤、並びに、体表適用製剤保持シート
EP2231257A4 (en) 2007-12-24 2013-11-06 Univ Queensland APPLICATION METHOD
EP2247527A4 (en) * 2008-02-07 2014-10-29 Univ Queensland PATCH PRODUCTION
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
ES2462465T5 (es) 2008-05-21 2018-02-28 Ferring B.V. Desmopresina bucodispersable para aumentar el periodo inicial del sueño no alterado por nocturia
WO2009140735A1 (en) * 2008-05-23 2009-11-26 The University Of Queensland Analyte detection by microneedle patch with analyte selective reagents.
US8834446B2 (en) * 2008-06-12 2014-09-16 DePuy Synthes Products, LLC Pulsatile flux drug delivery
AU2009329806A1 (en) 2008-12-22 2010-07-01 The University Of Queensland Patch production
WO2010124255A2 (en) * 2009-04-24 2010-10-28 Corium International, Inc. Methods for manufacturing microprojection arrays
US20100286600A1 (en) * 2009-05-08 2010-11-11 Bommannan D Bommi Transdermal patch device
DE102009056746A1 (de) * 2009-12-04 2011-06-09 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System für die Verabreichung von Peptiden
DE102009056745A1 (de) 2009-12-04 2011-06-09 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System für die Verabreichung von Peptiden
US20110144591A1 (en) * 2009-12-11 2011-06-16 Ross Russell F Transdermal Delivery Device
US8911422B2 (en) * 2010-02-24 2014-12-16 Hisamitsu Pharmaceutical Co., Inc. Micro-needle device
JP6327852B2 (ja) 2010-05-04 2018-05-23 コリウム インターナショナル， インコーポレイテッド 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス
ES2734560T3 (es) * 2010-05-04 2019-12-10 Corium Int Inc Aplicadores para microagujas
ME02474B (me) 2010-05-12 2017-02-20 Radius Health Inc Terapijski režimi
EP3225247B1 (en) 2010-05-28 2020-09-02 3M Innovative Properties Company Aqueous formulations for coating microneedle arrays
WO2012006677A1 (en) 2010-07-14 2012-01-19 The University Of Queensland Patch applying apparatus
US9133182B2 (en) 2010-09-28 2015-09-15 Radius Health, Inc. Selective androgen receptor modulators
US8865741B2 (en) 2011-02-18 2014-10-21 Asana Biosciences, Llc Aminoindane compounds and use thereof in treating pain
US20120222979A1 (en) 2011-03-04 2012-09-06 Elwha LLC, a limited liability company of the State of Delaware Glassy compositions
US8301238B2 (en) * 2011-03-31 2012-10-30 Incline Therapeutics, Inc. Two-part electrotransport device
JP5870551B2 (ja) * 2011-08-26 2016-03-01 大日本印刷株式会社 マイクロニードルデバイスの製造方法
JP2013043034A (ja) * 2011-08-26 2013-03-04 Dainippon Printing Co Ltd マイクロニードルデバイスの製造方法
US11179553B2 (en) 2011-10-12 2021-11-23 Vaxxas Pty Limited Delivery device
HUE032240T2 (en) 2011-10-24 2017-09-28 Asana Biosciences Llc cyclohexylamines
KR101392947B1 (ko) 2011-12-13 2014-05-12 주식회사 스몰랩 섬유를 포함하는 미세돌기 마사지 패치 및 그 제조 방법
US20130296824A1 (en) * 2012-05-03 2013-11-07 Uc Biodevices Corporation Microneedle based transdermal drug delivery device and method
ES2743733T3 (es) * 2012-06-15 2020-02-20 Univ Washington Through Its Center For Commercialization Dispositivos de cierre de heridas basados en microestructuras
AU2013364053B2 (en) 2012-12-21 2018-08-30 Corium Pharma Solutions, Inc. Microarray for delivery of therapeutic agent and methods of use
BR122020006959B1 (pt) 2013-03-12 2022-04-26 Corium, Inc Aplicador de microprojeções
JP2016514133A (ja) 2013-03-15 2016-05-19 コリウム インターナショナル， インコーポレイテッド ポリマーを含まない微細構造物を含むマイクロアレイ、製造方法および使用方法
BR112015022625B1 (pt) 2013-03-15 2023-01-31 Corium, Inc Aparelho de microestrutura para entrega de agente terapêutico
EP3027263A1 (en) 2013-07-30 2016-06-08 ZP Opco, Inc. Low-profile microneedle patch applicator
US9782344B2 (en) 2013-08-22 2017-10-10 Zp Opco, Inc. Stable glucagon peptide formulations
WO2015027173A1 (en) 2013-08-22 2015-02-26 Zp Opco, Inc. Stable glucagon peptide formulations
CA2933811C (en) 2013-12-16 2021-02-09 Asana Biosciences, Llc P2x3 and/or p2x2/3 compounds and methods
RU2667621C2 (ru) * 2014-04-30 2018-09-21 Кимберли-Кларк Ворлдвайд, Инк. Устройства и способы трансдермальной доставки лекарств
GB201410270D0 (en) 2014-06-10 2014-07-23 Univ Belfast Cell delivery system and method
EP3188714A1 (en) 2014-09-04 2017-07-12 Corium International, Inc. Microstructure array, methods of making, and methods of use
JP6906885B2 (ja) 2014-11-14 2021-07-21 ロレアル しわを減少させるためのマイクロニードルシート
US9744209B2 (en) 2015-01-30 2017-08-29 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9687526B2 (en) 2015-01-30 2017-06-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9925233B2 (en) 2015-01-30 2018-03-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9744239B2 (en) 2015-01-30 2017-08-29 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9937223B2 (en) 2015-01-30 2018-04-10 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9750785B2 (en) 2015-01-30 2017-09-05 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
CA2975275C (en) 2015-02-02 2023-08-29 Vaxxas Pty Limited Microprojection array applicator and method
RU2737496C2 (ru) 2015-04-29 2020-12-01 Радиус Фармасьютикалз, Инк. Способы лечения рака
EP3310425B1 (en) * 2015-05-22 2021-01-20 L'Oréal Applicators for treating skin conditions
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
US11103259B2 (en) 2015-09-18 2021-08-31 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
EP3355981A4 (en) 2015-09-28 2019-05-22 Vaxxas Pty Limited MICROPROJECTION ARRANGEMENTS WITH IMPROVED SKIN-IMPROPER PROPERTIES AND METHOD THEREFOR
WO2017079611A1 (en) 2015-11-02 2017-05-11 Zp Opco, Inc. Stable glucagon peptide formulations
WO2017143345A1 (en) 2016-02-19 2017-08-24 Zp Opco, Inc. Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines
JP6920341B2 (ja) 2016-04-18 2021-08-18 ラジウス ヘルス，インコーポレイテッド アバロパラチドの製剤、その経皮パッチ、およびその使用
JP7221699B2 (ja) 2016-06-22 2023-02-14 エリプセス ファーマ エルティーディー Ａｒ＋乳癌の治療方法
CN109996546B (zh) 2016-09-30 2023-06-27 阿沙纳生物科学公司 P2x3和/或p2x2/3化合物及方法
US11351348B2 (en) * 2016-12-12 2022-06-07 Medrx Co., Ltd. Microneedle patch
FI3565542T3 (fi) 2017-01-05 2024-06-24 Radius Pharmaceuticals Inc Rad1901-2hcl:n polymorfisia muotoja
EP4306803A3 (en) 2017-03-31 2024-04-10 Vaxxas Pty Limited Device and method for coating surfaces
US11175128B2 (en) 2017-06-13 2021-11-16 Vaxxas Pty Limited Quality control of substrate coatings
EP4218893A1 (en) 2017-08-04 2023-08-02 Vaxxas Pty Limited Compact high mechanical energy storage and low trigger force actuator for the delivery of microprojection array patches (map)
CN111050749A (zh) 2017-08-23 2020-04-21 佐萨诺制药公司 快速实现佐米曲坦的治疗性浓度以用于治疗偏头痛和丛集性头痛的方法
US11660264B2 (en) 2017-08-23 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
US11660265B2 (en) 2018-06-28 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
US11643385B2 (en) 2018-07-04 2023-05-09 Radius Pharmaceuticals, Inc. Polymorphic forms of RAD1901-2HCl

Family Cites Families (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3123212A (en) 1964-03-03 Multiple disposable intracutaneous injector package
US25637A (en) * 1859-10-04 Cooking-stove
USRE25637E (en) 1964-09-08 Means for vaccinating
US2619962A (en) 1948-02-19 1952-12-02 Res Foundation Vaccination appliance
US2893392A (en) 1958-01-08 1959-07-07 American Cyanamid Co Article of manufacture for intracutaneous injections
US3072122A (en) 1959-01-15 1963-01-08 Rosenthal Sol Roy Package for transcutaneous injection
US3136314A (en) 1960-08-01 1964-06-09 Kravitz Harvey Vaccinating devices
US3221739A (en) 1962-03-26 1965-12-07 Rosenthal Sol Roy Injection device
US3221740A (en) 1962-08-31 1965-12-07 Rosenthal Sol Roy Injection device
US3470011A (en) * 1967-02-07 1969-09-30 American Cyanamid Co Process for applying liquid biologicals to applicators for intracutaneous injection
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US3678150A (en) 1971-07-27 1972-07-18 American Cyanamid Co Process for improving the stability of ppd, qt and histoplasmin on tine applicators
CH580961A5 (en) * 1972-01-13 1976-10-29 Alza Corp Dispenser - functioning by osmotic pressure using active agents in solid or semi solid form
BE795384A (fr) 1972-02-14 1973-08-13 Ici Ltd Pansements
OA05448A (fr) 1975-10-16 1981-03-31 Manufrance Manufacture Francai Dispositif vaccinateur multipénétrant.
FR2474856A1 (fr) 1980-01-31 1981-08-07 Merieux Inst Dispositif scarificateur
SE8501990D0 (sv) 1985-04-24 1985-04-24 Pharmacia Ab Beleggningsforfarande
US4878892A (en) * 1987-02-10 1989-11-07 Drug Delivery Systems Inc. Electrolytic transdermal delivery of polypeptides
CA2016900A1 (en) 1989-07-06 1991-01-06 Ronald J. Filipski Tines structure in clinical applicator
EP0429842B1 (en) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US5321008A (en) * 1991-01-10 1994-06-14 Amylin Pharmaceuticals, Inc. Methods and compositions for treatment of diabetes mellitus, hypoglycemia, and other conditions
US5298256A (en) * 1992-04-28 1994-03-29 Corint, Ltd. Desmopressin buccal patch composition
US5457041A (en) * 1994-03-25 1995-10-10 Science Applications International Corporation Needle array and method of introducing biological substances into living cells using the needle array
US5487726A (en) 1994-06-16 1996-01-30 Ryder International Corporation Vaccine applicator system
EP0773781B1 (en) 1994-08-04 2003-10-22 Elan Drug Delivery Limited Solid delivery systems for controlled release of molecules incorporated therein and methods of making same
AU3758595A (en) 1994-09-30 1996-04-26 Rutgers, The State University Direct introduction of foreign materials into cells
ATE177325T1 (de) 1994-12-09 1999-03-15 Novartis Erfind Verwalt Gmbh Transdermales system
US5985316A (en) * 1995-04-28 1999-11-16 Alza Corporation Composition and method of enhancing electrotransport agent delivery
AU5740496A (en) 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
WO1996037256A1 (en) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical patch for enhancing the delivery of compounds through the skin
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
US6143037A (en) 1996-06-12 2000-11-07 The Regents Of The University Of Michigan Compositions and methods for coating medical devices
ZA975326B (en) 1996-06-18 1998-01-14 Alza Corp Device and method for enhancing transdermal flux of agents being delivered or sampled.
ES2200187T3 (es) 1996-07-03 2004-03-01 Altea Therapeutics Corporation Microporacion mecanica multiple de la piel o de la mucosa.
US5916524A (en) 1997-07-23 1999-06-29 Bio-Dot, Inc. Dispensing apparatus having improved dynamic range
US5738728A (en) 1996-07-26 1998-04-14 Bio Dot, Inc. Precision metered aerosol dispensing apparatus
US5743960A (en) 1996-07-26 1998-04-28 Bio-Dot, Inc. Precision metered solenoid valve dispenser
US5741554A (en) 1996-07-26 1998-04-21 Bio Dot, Inc. Method of dispensing a liquid reagent
CA2265906C (en) 1996-09-17 2003-11-11 Deka Products Limited Partnership System for delivery of drugs by transport
GB9623634D0 (en) 1996-11-13 1997-01-08 Bpsi Holdings Inc Method and apparatus for the coating of substrates for pharmaceutical use
ES2195190T3 (es) 1996-12-20 2003-12-01 Alza Corp Dispositivo y metodo para mejorar el flujo de agente transdermico.
DE19654391A1 (de) 1996-12-27 1998-07-02 Basf Ag Katalysator zur selektiven Herstellung von Propylen aus Propan
BR9714113A (pt) 1996-12-31 2000-03-21 Shell Int Research Plataforma de tirante
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
ATE406935T1 (de) 1997-12-11 2008-09-15 Alza Corp Vorrichtung zur verbesserung des transdermalen flusses von medikamenten
KR100572539B1 (ko) 1997-12-11 2006-04-24 알자 코포레이션 경피성 작용제 유동률을 증진시키기 위한 장치
CA2313698C (en) 1997-12-11 2008-04-15 Alza Corporation Device for enhancing transdermal agent flux
US6091975A (en) 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
EP1086214B1 (en) 1998-06-10 2009-11-25 Georgia Tech Research Corporation Microneedle devices and methods of their manufacture
WO2000012173A1 (en) 1998-08-31 2000-03-09 Johnson & Johnson Consumer Companies, Inc. Electrotransport device comprising blades
AU2189400A (en) 1998-12-18 2000-07-03 Minimed, Inc. Insertion sets with micro-piercing members for use with medical devices and methods of using the same
JP4072268B2 (ja) 1998-12-24 2008-04-09 キヤノン株式会社 皮膚吸収型薬液投与装置
DE60007290T2 (de) 1999-01-28 2004-09-23 Cyto Pulse Sciences, Inc. Einbringen von makromolekülen in zellen
US6537242B1 (en) * 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US6589202B1 (en) * 2000-06-29 2003-07-08 Becton Dickinson And Company Method and apparatus for transdermally sampling or administering a substance to a patient
GB0017999D0 (en) 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
AU8877401A (en) * 2000-09-08 2002-03-22 Alza Corp Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure
AU9682801A (en) 2000-10-13 2002-04-22 Alza Corp Apparatus and method for piercing skin with microprotrusions
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
IL155375A0 (en) * 2000-10-13 2003-11-23 Alza Corp Microblade array impact applicator
HUP0303576A2 (en) * 2000-10-13 2004-01-28 Alza Corp Microprotrusion member retainer for impact applicator
US6855372B2 (en) 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
CN100349632C (zh) * 2001-04-20 2007-11-21 阿尔扎公司 具有包含有益药剂的涂层的微小突出物阵列
US20030199810A1 (en) * 2001-11-30 2003-10-23 Trautman Joseph Creagan Methods and apparatuses for forming microprojection arrays
HUP0402605A2 (hu) * 2001-12-20 2005-06-28 Alza Corporation Eszköz mikroszkopikus bemetszések ejtésére állat bőrszövetén
US7015262B2 (en) 2002-05-01 2006-03-21 Lifescan, Inc. Hydrophilic coatings for medical implements
AU2003279641B2 (en) 2002-06-28 2009-06-18 Alza Corporation Transdermal drug delivery devices having coated microprotrusions
AR042815A1 (es) * 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
EP1638523B8 (en) * 2003-06-30 2013-12-25 ALZA Corporation Formulations for coated microprojections containing non-volatile counterions
CN1897883A (zh) * 2003-10-28 2007-01-17 阿尔扎公司 通过涂覆的微喷射体释放治疗用肽和蛋白的聚合物缀合物
JP4682144B2 (ja) * 2003-10-31 2011-05-11 アルザ・コーポレーシヨン 微小突起列のための自己−作動性アプリケーター
WO2005051456A2 (en) * 2003-11-13 2005-06-09 Alza Corporation Composition and apparatus for transdermal delivery
JP5007427B2 (ja) * 2004-05-13 2012-08-22 アルザ コーポレイション 副甲状腺ホルモン剤の経皮送達のための装置および方法
CA2593112A1 (en) * 2005-01-21 2006-07-27 Alza Corporation Therapeutic peptide formulations for coating microneedles with improved stability containing at least one counterion
CA2596075A1 (en) * 2005-01-31 2006-08-10 Alza Corporation Coated microprojections having reduced variability and method for producing same

Also Published As

Publication number Publication date
US20060200069A1 (en) 2006-09-07
ATE428466T1 (de) 2009-05-15
EP2085109A3 (en) 2009-09-02
EP1333880A1 (en) 2003-08-13
MXPA03003815A (es) 2004-08-12
US20020128599A1 (en) 2002-09-12
CN1239212C (zh) 2006-02-01
CN1501826A (zh) 2004-06-02
US7537795B2 (en) 2009-05-26
KR100812097B1 (ko) 2008-03-12
RU2282468C2 (ru) 2006-08-27
EP1333880B1 (en) 2009-04-15
JP2004520152A (ja) 2004-07-08
NO20031875D0 (no) 2003-04-25
PT1333880E (pt) 2009-05-11
DE60138407D1 (de) 2009-05-28
US8663155B2 (en) 2014-03-04
MA26061A1 (fr) 2004-04-01
CZ20031164A3 (cs) 2004-04-14
KR20030060922A (ko) 2003-07-16
BR0114909A (pt) 2004-02-03
AU2001297823B2 (en) 2005-05-12
IL155583A0 (en) 2003-11-23
ES2322023T3 (es) 2009-06-16
CA2427381A1 (en) 2002-11-28
NZ525551A (en) 2005-09-30
DK1333880T3 (da) 2009-07-20
WO2002094368A1 (en) 2002-11-28
JP2007075629A (ja) 2007-03-29
JP4875457B2 (ja) 2012-02-15
JP4659336B2 (ja) 2011-03-30
ZA200303988B (en) 2004-05-21
EP2085109A2 (en) 2009-08-05
HUP0302924A2 (en) 2003-12-29
NO20031875L (no) 2003-06-23

Similar Documents

Publication Publication Date Title
IL155583A0 (en) Transdermal drug delivery devices having coated microprotrusions
NZ520015A (en) Hydroxide-releasing agents as skin permeation enhancers
ATE357265T1 (de) Ladung und abgabe von wasser unlöslicher arzneimittel
WO2004030743A3 (en) Drug delivery device having coated microprojections incorporating vasoconstrictors
KR900701274A (ko) 남용 가능성을 감소시킨 용량 제형
BR0014929A (pt) Dispositivo para distribuição de medicamento, e, processo para distribuir um agente farmaceuticamente ativo para um tecido alvo dentro de um corpo
IE904290A1 (en) Transdermal therapeutic system containing buprenorphine as an active component
HK1071847A1 (en) Dosage forms having prolonged active ingredient release
NO993385D0 (no) Transdermalt terapeutisk system for avgivelse av hormoner
CA2079106A1 (en) Drug delivery systems containing eriodictyon fluid extract as an excipient, and methods and compositions associated therewith
TR200103613T2 (tr) Burun içinden tatbik edilen morfini içeren farmasötik formülasyonlar ve yöntemler.
ATE388687T1 (de) Medikamentöse verabreichung von nikotin in form von kaugummi
DK324687A (da) Transdermalt farmeceutisk praeparat
WO2001013898A3 (en) Pharmaceutical formulations with different release times
NO20021681D0 (no) Anordning for avlevering av medikament, med fuktighetsbestandig belegg
JP2001089359A (ja) 鎮痛成分の点鼻用ゲルまたはゾル製剤
WO2000026185A3 (en) Omeprazole solution and method of using same
US4873266A (en) Menthone enhancement of transdermal drug delivery
ES2188513T3 (es) Utilizacion de desoxipeganina para el tratamiento de la drogodependencia.
JP3425469B2 (ja) ジェットインジェクション経皮吸収装置
MX9306791A (es) Suministro transdermico de cetorolac.
CA2393452A1 (en) Use of histamine as a drug delivery enhancing compound for use in transmucosal or transdermal delivery
JP2002520269A5 (pl)
AR024199A1 (es) Uso de la buprenorfina en la preparacion de un disposotivo de suministro transdermico

Legal Events

Date Code Title Description
DISC Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)