TR200103613T2 - Burun içinden tatbik edilen morfini içeren farmasötik formülasyonlar ve yöntemler. - Google Patents

Burun içinden tatbik edilen morfini içeren farmasötik formülasyonlar ve yöntemler.

Info

Publication number
TR200103613T2
TR200103613T2 TR2001/03613T TR200103613T TR200103613T2 TR 200103613 T2 TR200103613 T2 TR 200103613T2 TR 2001/03613 T TR2001/03613 T TR 2001/03613T TR 200103613 T TR200103613 T TR 200103613T TR 200103613 T2 TR200103613 T2 TR 200103613T2
Authority
TR
Turkey
Prior art keywords
pharmaceutical formulations
administered intranasally
morphine
methods containing
pharmaceutically acceptable
Prior art date
Application number
TR2001/03613T
Other languages
English (en)
Inventor
G. Achari Raja
R. Behl Charanjit
C. Demeireles Jorge
Dua Ramneik
D. ROMEO(vefat etmi�) VINCENT
P. Sileno Anthony
Original Assignee
Nastech Pharmaceutical Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nastech Pharmaceutical Co., Inc. filed Critical Nastech Pharmaceutical Co., Inc.
Publication of TR200103613T2 publication Critical patent/TR200103613T2/tr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Bu bulus, 3.0' dan 7.0' a kadar bir pH' da morfin ya da farmasötik açidan kabul edilebilir tuzunu içeren, bunun içinden tatbikat için bir farmasötik formülasyona iliskindir. Bu formülasyonlar, morfin ya da farmasötik açidan kabul edilebilir tuzlarinin emilmesinde artis temin etmektedir. Bir düzenlemede, bu bulus, bir memelide bir analjesik ya da anastetik karsiligin orataya çikartilmasi için bir yöntem temin etmektedir, bu yöntem, 3.0' dan 7.0^ a kadar bir pH' da morfin ya da farmasötik açidan kabul edilebilir tuzunun terapötik açidan etkili bir miktarinin burundan tatbik edilmesini kapsamaktadir.
TR2001/03613T 1999-06-16 2000-05-23 Burun içinden tatbik edilen morfini içeren farmasötik formülasyonlar ve yöntemler. TR200103613T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33453799A 1999-06-16 1999-06-16

Publications (1)

Publication Number Publication Date
TR200103613T2 true TR200103613T2 (tr) 2004-08-23

Family

ID=23307687

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/03613T TR200103613T2 (tr) 1999-06-16 2000-05-23 Burun içinden tatbik edilen morfini içeren farmasötik formülasyonlar ve yöntemler.

Country Status (30)

Country Link
US (1) US6677346B1 (tr)
EP (2) EP1183027A4 (tr)
JP (1) JP2003501467A (tr)
KR (1) KR20020016831A (tr)
AU (1) AU774175B2 (tr)
BG (1) BG106221A (tr)
BR (1) BR0012082A (tr)
CA (1) CA2374877C (tr)
CZ (1) CZ20014399A3 (tr)
DE (1) DE10084709T1 (tr)
DK (1) DK200101859A (tr)
EE (1) EE200100677A (tr)
ES (1) ES2197792B1 (tr)
FI (1) FI20012462L (tr)
GB (1) GB2367005A (tr)
HR (1) HRP20010926A2 (tr)
HU (1) HUP0201856A3 (tr)
IS (1) IS6202A (tr)
LT (1) LT4976B (tr)
LU (1) LU90859B1 (tr)
LV (1) LV12859B (tr)
MX (1) MXPA01012879A (tr)
NO (1) NO20015931L (tr)
NZ (1) NZ515783A (tr)
PL (1) PL352556A1 (tr)
SE (1) SE0104203D0 (tr)
SI (1) SI20850A (tr)
SK (1) SK18172001A3 (tr)
TR (1) TR200103613T2 (tr)
WO (1) WO2000076506A1 (tr)

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Publication number Priority date Publication date Assignee Title
GB9924797D0 (en) 1999-10-20 1999-12-22 West Pharm Serv Drug Res Ltd Compound
US20060083691A1 (en) * 2000-05-10 2006-04-20 Wermeling Daniel P Intranasal opioid compositions, delivery devices and methods of using same
US20040115133A1 (en) * 2000-05-10 2004-06-17 Wermeling Daniel P. Intranasal opioid compositions
US6572849B2 (en) * 2000-09-20 2003-06-03 Lee Shahinian, Jr. Self-preserved antibacterial nasal, inhalable, and topical ophthalmic preparations and medications
EP1418862A4 (en) * 2001-06-29 2010-06-09 Leon J Lewandowski INDIVIDUALIZED SEARCH THERAPY
GB0210264D0 (en) * 2002-05-03 2002-06-12 Arakis Ltd The treatment of pain and migraine headache
US20040102476A1 (en) * 2002-11-25 2004-05-27 Chan Tai Wah High concentration formulations of opioids and opioid derivatives
US20050175679A1 (en) * 2004-02-10 2005-08-11 Michael Moshman Controlled release formulations
US20140162965A1 (en) 2004-08-25 2014-06-12 Aegis Therapeutics, Inc. Compositions for oral drug administration
US9895444B2 (en) 2004-08-25 2018-02-20 Aegis Therapeutics, Llc Compositions for drug administration
PT2486942T (pt) 2004-11-24 2019-01-18 Meda Pharmaceuticals Inc Composições que compreendem azelastina e seus métodos de utilização
US9415034B2 (en) * 2005-01-05 2016-08-16 National Defense Medical Center Inhibitors and enhancers of uridine diphosphate-glucuronosyltransferase 2B (UGT2B)
ES2277743B2 (es) * 2005-06-02 2008-12-16 Universidade De Santiago De Compostela Nanoparticulas que comprenden quitosano y ciclodextrina.
ATE458491T1 (de) 2005-08-26 2010-03-15 Univ Leland Stanford Junior Verfahren zur behandlung von kopfschmerzen durch verabreichung von oxytocin
US20070212307A1 (en) * 2006-02-10 2007-09-13 Daniel Wermeling Pharmaceutical Compositions Comprising an Opioid Receptor Antagonist and Methods of Using Same
US8226949B2 (en) 2006-06-23 2012-07-24 Aegis Therapeutics Llc Stabilizing alkylglycoside compositions and methods thereof
WO2008077712A1 (en) * 2006-12-22 2008-07-03 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Gel useful for the delivery of ophthalmic drugs
GB2477545B (en) * 2010-02-05 2011-12-21 Special Products Ltd A liquid morphine composition for buccal administration
LT2706982T (lt) 2011-05-13 2018-05-25 Euro-Celtique S.A. Intranazalinės farmacinės vaisto formos, apimančios naloksoną
WO2014016653A1 (en) 2012-07-26 2014-01-30 Wockhardt Limited Pharmaceutical composition comprising diamorphine for intranasal administration
EP3082817A4 (en) * 2013-12-18 2017-06-21 Aegis Therapeutics, LLC Compositions for drug administration
US11135155B2 (en) 2014-07-08 2021-10-05 Hikma Pharmaceuticals Usa Inc. Liquid naloxone spray
PL3242676T3 (pl) 2015-01-07 2024-07-15 Tonix Pharma Limited Preparaty oksytocyny zawierające magnez i sposoby ich stosowania
HUE070412T2 (hu) 2016-04-12 2025-06-28 Tonix Pharma Ltd Magnézium tartalmú oxitocin készítmények és alkamazási eljárásaik
CA3041309A1 (en) * 2016-10-21 2018-04-26 Somniferum Labs LLC Compositions, methods and kits for the safe inhaled delivery of targeted opioids for the treatment of pain and addiction
EP3697381B1 (en) * 2017-10-20 2023-06-07 Chiesi Farmaceutici S.p.A. Pharmaceutical formulations comprising opioid receptor agonist as active ingredients, methods of manufacture and therapeutic uses thereof
WO2019157099A1 (en) 2018-02-06 2019-08-15 Aegis Therapeutics, Llc Intranasal epinephrine formulations and methods for the treatment of disease
CN115804754A (zh) * 2022-12-16 2023-03-17 广州新济药业科技有限公司 吗啡鼻喷剂及其制备方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464378A (en) * 1981-04-28 1984-08-07 University Of Kentucky Research Foundation Method of administering narcotic antagonists and analgesics and novel dosage forms containing same
US4464376A (en) 1982-07-22 1984-08-07 Richardson-Vicks, Inc. Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same
GB8514665D0 (en) * 1985-06-11 1985-07-10 Eroceltique Sa Oral pharmaceutical composition
US5202128A (en) 1989-01-06 1993-04-13 F. H. Faulding & Co. Limited Sustained release pharmaceutical composition
GB9202464D0 (en) * 1992-02-05 1992-03-18 Danbiosyst Uk Composition for nasal administration
DK0689438T3 (da) * 1993-03-26 2003-09-29 Franciscus Wilhelmus He Merkus Farmaceutiske præparater til intranasal administration af apomorfin
GB9426102D0 (en) 1994-12-23 1995-02-22 Merck Sharp & Dohme Pharmacuetical compositions
EP1006969A1 (en) * 1996-09-27 2000-06-14 Nastech Pharmaceutical Co. Intranasal formulations for promoting sleep and method of using the same

Also Published As

Publication number Publication date
EP1183027A1 (en) 2002-03-06
KR20020016831A (ko) 2002-03-06
FI20012462A7 (fi) 2002-01-16
DK200101859A (da) 2001-12-12
AU5156100A (en) 2001-01-02
MXPA01012879A (es) 2003-06-24
EE200100677A (et) 2003-02-17
HUP0201856A3 (en) 2004-12-28
ES2197792A1 (es) 2004-01-01
EP1419774A1 (en) 2004-05-19
GB0128383D0 (en) 2002-01-16
ES2197792B1 (es) 2005-05-01
LV12859B (en) 2002-12-20
CA2374877C (en) 2004-04-13
LT4976B (lt) 2002-12-30
SI20850A (sl) 2002-10-31
NO20015931L (no) 2002-02-08
LT2001119A (en) 2002-07-25
GB2367005A (en) 2002-03-27
US6677346B1 (en) 2004-01-13
WO2000076506A1 (en) 2000-12-21
NZ515783A (en) 2004-05-28
DE10084709T1 (de) 2002-09-26
FI20012462L (fi) 2002-01-16
AU774175B2 (en) 2004-06-17
SE0104203L (sv) 2001-12-14
BR0012082A (pt) 2002-05-07
CA2374877A1 (en) 2000-12-21
HRP20010926A2 (en) 2003-04-30
PL352556A1 (en) 2003-08-25
SK18172001A3 (sk) 2002-07-02
JP2003501467A (ja) 2003-01-14
BG106221A (bg) 2002-08-30
EP1183027A4 (en) 2003-02-05
CZ20014399A3 (cs) 2002-06-12
LU90859B1 (en) 2002-01-24
SE0104203D0 (sv) 2001-12-14
NO20015931D0 (no) 2001-12-04
IS6202A (is) 2001-12-14
HUP0201856A1 (en) 2002-09-28

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