TR200103613T2 - Burun içinden tatbik edilen morfini içeren farmasötik formülasyonlar ve yöntemler. - Google Patents

Burun içinden tatbik edilen morfini içeren farmasötik formülasyonlar ve yöntemler.

Info

Publication number
TR200103613T2
TR200103613T2 TR2001/03613T TR200103613T TR200103613T2 TR 200103613 T2 TR200103613 T2 TR 200103613T2 TR 2001/03613 T TR2001/03613 T TR 2001/03613T TR 200103613 T TR200103613 T TR 200103613T TR 200103613 T2 TR200103613 T2 TR 200103613T2
Authority
TR
Turkey
Prior art keywords
pharmaceutical formulations
administered intranasally
morphine
methods containing
pharmaceutically acceptable
Prior art date
Application number
TR2001/03613T
Other languages
English (en)
Inventor
G. Achari Raja
R. Behl Charanjit
C. Demeireles Jorge
Dua Ramneik
D. ROMEO(vefat etmi�) VINCENT
P. Sileno Anthony
Original Assignee
Nastech Pharmaceutical Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nastech Pharmaceutical Co., Inc. filed Critical Nastech Pharmaceutical Co., Inc.
Publication of TR200103613T2 publication Critical patent/TR200103613T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Bu bulus, 3.0' dan 7.0' a kadar bir pH' da morfin ya da farmasötik açidan kabul edilebilir tuzunu içeren, bunun içinden tatbikat için bir farmasötik formülasyona iliskindir. Bu formülasyonlar, morfin ya da farmasötik açidan kabul edilebilir tuzlarinin emilmesinde artis temin etmektedir. Bir düzenlemede, bu bulus, bir memelide bir analjesik ya da anastetik karsiligin orataya çikartilmasi için bir yöntem temin etmektedir, bu yöntem, 3.0' dan 7.0^ a kadar bir pH' da morfin ya da farmasötik açidan kabul edilebilir tuzunun terapötik açidan etkili bir miktarinin burundan tatbik edilmesini kapsamaktadir.
TR2001/03613T 1999-06-16 2000-05-23 Burun içinden tatbik edilen morfini içeren farmasötik formülasyonlar ve yöntemler. TR200103613T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33453799A 1999-06-16 1999-06-16

Publications (1)

Publication Number Publication Date
TR200103613T2 true TR200103613T2 (tr) 2004-08-23

Family

ID=23307687

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/03613T TR200103613T2 (tr) 1999-06-16 2000-05-23 Burun içinden tatbik edilen morfini içeren farmasötik formülasyonlar ve yöntemler.

Country Status (30)

Country Link
US (1) US6677346B1 (tr)
EP (2) EP1419774A1 (tr)
JP (1) JP2003501467A (tr)
KR (1) KR20020016831A (tr)
AU (1) AU774175B2 (tr)
BG (1) BG106221A (tr)
BR (1) BR0012082A (tr)
CA (1) CA2374877C (tr)
CZ (1) CZ20014399A3 (tr)
DE (1) DE10084709T1 (tr)
DK (1) DK200101859A (tr)
EE (1) EE200100677A (tr)
ES (1) ES2197792B1 (tr)
FI (1) FI20012462L (tr)
GB (1) GB2367005A (tr)
HR (1) HRP20010926A2 (tr)
HU (1) HUP0201856A3 (tr)
IS (1) IS6202A (tr)
LT (1) LT4976B (tr)
LU (1) LU90859B1 (tr)
LV (1) LV12859B (tr)
MX (1) MXPA01012879A (tr)
NO (1) NO20015931L (tr)
NZ (1) NZ515783A (tr)
PL (1) PL352556A1 (tr)
SE (1) SE0104203L (tr)
SI (1) SI20850A (tr)
SK (1) SK18172001A3 (tr)
TR (1) TR200103613T2 (tr)
WO (1) WO2000076506A1 (tr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9924797D0 (en) 1999-10-20 1999-12-22 West Pharm Serv Drug Res Ltd Compound
US20040115133A1 (en) * 2000-05-10 2004-06-17 Wermeling Daniel P. Intranasal opioid compositions
US20060083691A1 (en) * 2000-05-10 2006-04-20 Wermeling Daniel P Intranasal opioid compositions, delivery devices and methods of using same
US6572849B2 (en) * 2000-09-20 2003-06-03 Lee Shahinian, Jr. Self-preserved antibacterial nasal, inhalable, and topical ophthalmic preparations and medications
WO2003002071A2 (en) * 2001-06-29 2003-01-09 Lewandowski Leon J Individualized addiction cessation therapy
GB0210264D0 (en) * 2002-05-03 2002-06-12 Arakis Ltd The treatment of pain and migraine headache
US20040102476A1 (en) * 2002-11-25 2004-05-27 Chan Tai Wah High concentration formulations of opioids and opioid derivatives
US20050175679A1 (en) * 2004-02-10 2005-08-11 Michael Moshman Controlled release formulations
US20140162965A1 (en) 2004-08-25 2014-06-12 Aegis Therapeutics, Inc. Compositions for oral drug administration
US9895444B2 (en) 2004-08-25 2018-02-20 Aegis Therapeutics, Llc Compositions for drug administration
PL2486942T3 (pl) 2004-11-24 2019-05-31 Meda Pharmaceuticals Inc Kompozycje zawierające azelastynę oraz sposoby ich stosowania
US9415034B2 (en) * 2005-01-05 2016-08-16 National Defense Medical Center Inhibitors and enhancers of uridine diphosphate-glucuronosyltransferase 2B (UGT2B)
ES2277743B2 (es) 2005-06-02 2008-12-16 Universidade De Santiago De Compostela Nanoparticulas que comprenden quitosano y ciclodextrina.
CA2620364A1 (en) 2005-08-26 2007-03-01 David C. Yeomans Methods for treatment of headaches by administration of oxytocin
US20070212307A1 (en) * 2006-02-10 2007-09-13 Daniel Wermeling Pharmaceutical Compositions Comprising an Opioid Receptor Antagonist and Methods of Using Same
US8226949B2 (en) 2006-06-23 2012-07-24 Aegis Therapeutics Llc Stabilizing alkylglycoside compositions and methods thereof
EA016795B1 (ru) * 2006-12-22 2012-07-30 Сигма-Тау Индустрие Фармасьютике Риуните С.П.А. Гель, применимый для доставки офтальмологических лекарственных средств
GB2477545B (en) * 2010-02-05 2011-12-21 Special Products Ltd A liquid morphine composition for buccal administration
ME02958B (me) 2011-05-13 2018-07-20 Euro Celtique Sa Intranazalni farmaceutski dozni oblici коji obuhvataju nalokson
WO2014016653A1 (en) 2012-07-26 2014-01-30 Wockhardt Limited Pharmaceutical composition comprising diamorphine for intranasal administration
EP3082817A4 (en) * 2013-12-18 2017-06-21 Aegis Therapeutics, LLC Compositions for drug administration
US11135155B2 (en) 2014-07-08 2021-10-05 Hikma Pharmaceuticals Usa Inc. Liquid naloxone spray
LT3242676T (lt) 2015-01-07 2024-01-25 Tonix Pharma Limited Oksitocino vaistinės formos, kurių sudėtyje yra magnio, ir jų naudojimo būdai
ES3014046T3 (en) 2016-04-12 2025-04-16 Tonix Pharma Ltd Magnesium-containing oxytocin formulations and methods of use
EP3528873A2 (en) * 2016-10-21 2019-08-28 Somniferum Labs LLC Apparatus for controlled delivery of opioid and other medications
JP7378391B2 (ja) * 2017-10-20 2023-11-13 シエシー ファルマセウティチィ ソシエタ ペル アチオニ 有効成分としてオピオイド受容体アゴニストを含む医薬製剤、その製造方法および治療的使用
EA202091615A1 (ru) 2018-12-21 2021-03-05 Аегис Терапьютикс, Ллс Интраназальные составы на основе эпинефрина и способы лечения заболевания
CN115804754A (zh) * 2022-12-16 2023-03-17 广州新济药业科技有限公司 吗啡鼻喷剂及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464378A (en) 1981-04-28 1984-08-07 University Of Kentucky Research Foundation Method of administering narcotic antagonists and analgesics and novel dosage forms containing same
US4464376A (en) 1982-07-22 1984-08-07 Richardson-Vicks, Inc. Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same
GB8514665D0 (en) * 1985-06-11 1985-07-10 Eroceltique Sa Oral pharmaceutical composition
US5202128A (en) 1989-01-06 1993-04-13 F. H. Faulding & Co. Limited Sustained release pharmaceutical composition
GB9202464D0 (en) * 1992-02-05 1992-03-18 Danbiosyst Uk Composition for nasal administration
DK0689438T3 (da) * 1993-03-26 2003-09-29 Franciscus Wilhelmus He Merkus Farmaceutiske præparater til intranasal administration af apomorfin
GB9426102D0 (en) 1994-12-23 1995-02-22 Merck Sharp & Dohme Pharmacuetical compositions
JP2001501212A (ja) * 1996-09-27 2001-01-30 ナステック ファーマシューティカル カンパニー インク 睡眠促進用鼻腔内調製物及び同物を用いる方法

Also Published As

Publication number Publication date
NZ515783A (en) 2004-05-28
CZ20014399A3 (cs) 2002-06-12
AU5156100A (en) 2001-01-02
JP2003501467A (ja) 2003-01-14
LV12859B (en) 2002-12-20
KR20020016831A (ko) 2002-03-06
IS6202A (is) 2001-12-14
HRP20010926A2 (en) 2003-04-30
DK200101859A (da) 2001-12-12
EE200100677A (et) 2003-02-17
GB2367005A (en) 2002-03-27
BR0012082A (pt) 2002-05-07
FI20012462A7 (fi) 2002-01-16
GB0128383D0 (en) 2002-01-16
ES2197792A1 (es) 2004-01-01
EP1183027A1 (en) 2002-03-06
HUP0201856A3 (en) 2004-12-28
CA2374877C (en) 2004-04-13
AU774175B2 (en) 2004-06-17
SE0104203D0 (sv) 2001-12-14
PL352556A1 (en) 2003-08-25
LT2001119A (en) 2002-07-25
US6677346B1 (en) 2004-01-13
LT4976B (lt) 2002-12-30
SE0104203L (sv) 2001-12-14
SI20850A (sl) 2002-10-31
NO20015931D0 (no) 2001-12-04
CA2374877A1 (en) 2000-12-21
EP1419774A1 (en) 2004-05-19
ES2197792B1 (es) 2005-05-01
SK18172001A3 (sk) 2002-07-02
LU90859B1 (en) 2002-01-24
NO20015931L (no) 2002-02-08
MXPA01012879A (es) 2003-06-24
FI20012462L (fi) 2002-01-16
BG106221A (bg) 2002-08-30
EP1183027A4 (en) 2003-02-05
DE10084709T1 (de) 2002-09-26
HUP0201856A1 (en) 2002-09-28
WO2000076506A1 (en) 2000-12-21

Similar Documents

Publication Publication Date Title
TR200103613T2 (tr) Burun içinden tatbik edilen morfini içeren farmasötik formülasyonlar ve yöntemler.
WO2000021515A3 (en) Intranasal codeine for the rapid suppression of cough and rapid relief of pain
DK0938316T3 (da) Opioidantagonistholdig galenisk formulering
WO2002042462A3 (en) Therapeutic agents and methods of use thereof for treating an amyloidogenic disease
NZ508526A (en) Opioid formulations for treating pain
DK0754034T3 (da) Brusende farmaceutiske formuleringer indeholdende biologisk nedbrydelige mikrokapsler med kontrolleret afgivelse
NO925038D0 (no) Anordning for nedsettelse av medikamentets hudirriterendevirkninger
NO952906D0 (no) Farmasöytisk formulering for behandling av nikotinavhengighet
TR199900336T2 (tr) EAA antagonistleri olarak tetrahidrokinolin türevleri.
SE9601528D0 (sv) Transdermally administered dextromethorphan as antitissue agent
DE69824313D1 (de) Sibutramin und orlistat enthaltende pharmazeutische zusammensetzungen
EP0799618A3 (en) Use of alpha1-adrenoreceptor antagonists in the manufacture of a medicament for the prevention and teatment of cancer
BR0011880A (pt) Método para o tratamento de condições co-mórbidas associadas com obesidade, composto, produto, uso de um composto, e, composição farmacêutica
AU3278800A (en) Pharmaceutical composition containing desoxypeganine for the treatment of drug dependence
ATE302010T1 (de) Pharmazeutische zusammensetzung, enthaltend desoxypeganin zur behandlung des alkoholismus
WO2001000187A3 (en) Pharmaceutical composition containing sibutramine and a lipase inhibitor
TR200200111T2 (tr) Neoplazmalar için terapötik ve profilaktik maddeler
BR9607488A (pt) Um sistema terapêutico transdérmico para a administração de (s)-3-metil-5-(1-metil-2-pirrolidenil)-isoxazol ou um dos seus sais farmaceuticamente aceítaveis
MX9601033A (es) Nanosuspensiones para administracion intravenosa.