PL344863A1 - Improved in vivo - Google Patents

Improved in vivo

Info

Publication number
PL344863A1
PL344863A1 PL99344863A PL34486399A PL344863A1 PL 344863 A1 PL344863 A1 PL 344863A1 PL 99344863 A PL99344863 A PL 99344863A PL 34486399 A PL34486399 A PL 34486399A PL 344863 A1 PL344863 A1 PL 344863A1
Authority
PL
Poland
Prior art keywords
improved
host cell
vivo
host cells
localised
Prior art date
Application number
PL99344863A
Other languages
English (en)
Inventor
Maarten Nieboer
Roelof Ary Lans Bovenberg
Original Assignee
Dsm Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Nv filed Critical Dsm Nv
Publication of PL344863A1 publication Critical patent/PL344863A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL99344863A 1998-05-19 1999-05-19 Improved in vivo PL344863A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98201655 1998-05-19

Publications (1)

Publication Number Publication Date
PL344863A1 true PL344863A1 (en) 2001-11-19

Family

ID=8233737

Family Applications (1)

Application Number Title Priority Date Filing Date
PL99344863A PL344863A1 (en) 1998-05-19 1999-05-19 Improved in vivo

Country Status (16)

Country Link
US (2) US6995003B1 (enExample)
EP (2) EP1078069B1 (enExample)
JP (1) JP2003527069A (enExample)
KR (1) KR100648480B1 (enExample)
CN (2) CN101353660A (enExample)
AT (1) ATE386123T1 (enExample)
AU (1) AU4144999A (enExample)
BR (1) BR9910532A (enExample)
DE (1) DE69938129D1 (enExample)
ES (1) ES2302379T3 (enExample)
ID (1) ID27054A (enExample)
MX (1) MXPA00011223A (enExample)
PL (1) PL344863A1 (enExample)
RU (1) RU2230790C2 (enExample)
WO (1) WO1999060102A2 (enExample)
ZA (1) ZA200006308B (enExample)

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MY160995A (en) 2010-10-13 2017-03-28 Dsm Ip Assets Bv Polypeptides with permease activity
EA201301193A1 (ru) 2011-04-22 2014-02-28 ДСМ АйПи АССЕТС Б.В. Дрожжевые клетки, способные к превращению сахаров, содержащих арабинозу и ксилозу
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EA201400836A8 (ru) 2012-01-23 2016-03-31 ДСМ АйПи АССЕТС Б.В. Получение дитерпена
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EP2981610A1 (en) 2013-04-05 2016-02-10 Université du Luxembourg Biotechnological production of itaconic acid
EP2992105A1 (en) 2013-05-02 2016-03-09 Dutch DNA Biotech B.V. Novel organic acid pathway
CA2913876A1 (en) 2013-05-31 2014-12-04 Dsm Ip Assets B.V. Microorganisms for diterpene production
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CA2979957A1 (en) 2015-03-23 2016-09-29 Dsm Ip Assets B.V. Udp-glycosyltransferases from solanum lycopersicum
EP3718417B1 (en) 2015-04-03 2025-09-03 DSM IP Assets B.V. Steviol glycosides
CN107532135A (zh) 2015-04-21 2018-01-02 帝斯曼知识产权资产管理有限公司 萜类化合物的微生物生产
MY186983A (en) 2015-05-22 2021-08-26 Dsm Ip Assets Bv Acetate consuming yeast cell
EP3320104B1 (en) 2015-07-10 2021-11-10 DSM IP Assets B.V. Method for preparing a steviol glycoside composition
CA2993744A1 (en) 2015-08-13 2017-02-16 Dsm Ip Assets B.V. Steviol glycoside transport
WO2017050652A1 (en) 2015-09-25 2017-03-30 Dsm Ip Assets B.V. Asparaginase
CA2999638A1 (en) 2015-10-05 2017-04-13 Dsm Ip Assets B.V. Kaurenoic acid hydroxylases
EP3359655B1 (en) 2015-10-06 2019-11-20 DSM IP Assets B.V. Eukaryotic cell with increased production of fermentation product
WO2017115323A2 (en) 2015-12-30 2017-07-06 Dsm Ip Assets B.V. Partial enzymatic hydrolysis of triacylglycerols
WO2017115322A2 (en) 2015-12-30 2017-07-06 Dsm Ip Assets B.V. Partial enzymatic hydrolysis of triacylglycerols
WO2017167847A1 (en) 2016-03-31 2017-10-05 Dsm Ip Assets B.V. Production of milk with low lactose content
EP3435772A1 (en) 2016-03-31 2019-02-06 DSM IP Assets B.V. Enzyme composition and preparation of a dairy product with improved properties
WO2017167848A1 (en) 2016-03-31 2017-10-05 Dsm Ip Assets B.V. Enzyme composition and preparation of a dairy product with improved properties
CN109312296B (zh) 2016-06-14 2023-05-05 帝斯曼知识产权资产管理有限公司 重组酵母细胞
EP3919615A1 (en) 2016-07-13 2021-12-08 DSM IP Assets B.V. Malate dehyrogenases
EP3497109A1 (en) 2016-08-09 2019-06-19 DSM IP Assets B.V. Crystallization of steviol glycosides
EP3497110A1 (en) 2016-08-09 2019-06-19 DSM IP Assets B.V. Crystallization of steviol glycosides
CN110036114B (zh) 2016-08-26 2023-09-29 勒萨弗尔公司 提高的衣康酸生产
WO2018073107A1 (en) 2016-10-19 2018-04-26 Dsm Ip Assets B.V. Eukaryotic cell comprising xylose isomerase
WO2018078014A1 (en) 2016-10-27 2018-05-03 Dsm Ip Assets B.V. Geranylgeranyl pyrophosphate synthases
JP2020500520A (ja) 2016-12-08 2020-01-16 ディーエスエム アイピー アセッツ ビー.ブイ.Dsm Ip Assets B.V. カウレン酸ヒドロキシラーゼ
WO2018114912A1 (en) 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Lipolytic enzyme variants
EP3559222A1 (en) 2016-12-21 2019-10-30 DSM IP Assets B.V. Lipolytic enzyme variants
US10889807B2 (en) 2016-12-21 2021-01-12 Dsm Ip Assets B.V. Lipolytic enzyme variants
WO2018114938A1 (en) 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Lipolytic enzyme variants
WO2018114995A1 (en) 2016-12-22 2018-06-28 Dsm Ip Assets B.V. Fermentation process for producing steviol glycosides
CA3064143A1 (en) 2017-06-13 2018-12-20 Dsm Ip Assets B.V. Recombinant yeast cell
EP4155400A1 (en) 2017-06-27 2023-03-29 DSM IP Assets B.V. Udp-glycosyltransferases
CN111133111A (zh) 2017-09-26 2020-05-08 帝斯曼知识产权资产管理有限公司 消耗乙酸的菌株
EP3533878A1 (en) 2018-02-28 2019-09-04 Dutch DNA Biotech B.V. Process for producing citramalic acid employing aspergillus
MX2020014191A (es) 2018-06-19 2021-03-09 Dsm Ip Assets Bv Variantes de enzimas lipoliticas.
EP4232568A1 (en) 2020-10-22 2023-08-30 DSM IP Assets B.V. Microorganisms for diterpene production
WO2022269549A2 (en) 2021-06-24 2022-12-29 Fonterra Co-Operative Group Limited Recombinant proteins
US20250333768A1 (en) 2021-07-12 2025-10-30 Danisco Us Inc. Recombinant yeast cell
WO2023285280A1 (en) 2021-07-12 2023-01-19 Dsm Ip Assets B.V. Recombinant yeast cell
MX2024000606A (es) 2021-07-12 2024-01-30 Danisco Us Inc Celula de levadura recombinante.
EP4370692A1 (en) 2021-07-12 2024-05-22 Danisco Us Inc Recombinant yeast cell
MX2024000513A (es) 2021-07-12 2024-03-27 Danisco Us Inc Celula de levadura recombinante.
CN117916381A (zh) 2021-07-12 2024-04-19 丹尼斯科美国公司 重组酵母细胞
EP4426824A1 (en) 2021-11-04 2024-09-11 Danisco US Inc. Recombinant yeast cell
US20240425888A1 (en) 2021-11-04 2024-12-26 Danisco Us Inc. Process for the production of ethanol and recombinant yeast cell
US20240409965A1 (en) 2021-11-04 2024-12-12 Danisco Us Inc. Variant polypeptide and recombinant yeast cell
EP4430174A1 (en) 2021-11-09 2024-09-18 Amgen Inc. Production of therapeutic proteins
JP2025520009A (ja) 2022-05-16 2025-07-01 ディーエスエム アイピー アセッツ ビー.ブイ. 脂肪分解酵素変異体
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Also Published As

Publication number Publication date
CN101353660A (zh) 2009-01-28
JP2003527069A (ja) 2003-09-16
US20060127972A1 (en) 2006-06-15
ES2302379T3 (es) 2008-07-01
RU2230790C2 (ru) 2004-06-20
WO1999060102A3 (en) 2000-02-03
AU4144999A (en) 1999-12-06
EP1078069B1 (en) 2008-02-13
CN1301303A (zh) 2001-06-27
EP1078069A2 (en) 2001-02-28
ATE386123T1 (de) 2008-03-15
ZA200006308B (en) 2001-05-23
KR100648480B1 (ko) 2006-11-24
DE69938129D1 (de) 2008-03-27
EP1953230A1 (en) 2008-08-06
US6995003B1 (en) 2006-02-07
ID27054A (id) 2001-02-22
BR9910532A (pt) 2001-10-16
WO1999060102A2 (en) 1999-11-25
MXPA00011223A (es) 2002-04-17
CN100390285C (zh) 2008-05-28
KR20010025039A (ko) 2001-03-26

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