MX2020014191A - Variantes de enzimas lipoliticas. - Google Patents

Variantes de enzimas lipoliticas.

Info

Publication number
MX2020014191A
MX2020014191A MX2020014191A MX2020014191A MX2020014191A MX 2020014191 A MX2020014191 A MX 2020014191A MX 2020014191 A MX2020014191 A MX 2020014191A MX 2020014191 A MX2020014191 A MX 2020014191A MX 2020014191 A MX2020014191 A MX 2020014191A
Authority
MX
Mexico
Prior art keywords
polypeptide
seq
amino acid
lipolytic enzyme
enzyme variants
Prior art date
Application number
MX2020014191A
Other languages
English (en)
Inventor
Aloysius Wilhelmus Rudolphus Hubertus Teunissen
Jong René Marcel De
Neil Carr
Joke Anneleen Putseys
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of MX2020014191A publication Critical patent/MX2020014191A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
    • A21D6/00—Other treatment of flour or dough before baking, e.g. cooling, irradiating, heating
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
    • A21D8/00—Methods for preparing or baking dough
    • A21D8/02—Methods for preparing dough; Treating dough prior to baking
    • A21D8/04—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes
    • A21D8/042—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes with enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01003—Triacylglycerol lipase (3.1.1.3)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

La presente invención se refiere a un polipéptido variante que tiene actividad lipasa, en donde el polipéptido puede ser un polipéptido que tiene una secuencia de aminoácidos que tiene al menos un 70% de identidad con una secuencia de aminoácidos madura de SEQ ID NO: 1 o SEQ ID NO: 6, en donde el polipéptido comprende una sustitución de aminoácido en la posición 295 y al menos una sustitución de aminoácido adicional en la posición 113, 121, 179 y/o 284, donde las posiciones se definen con referencia a SEQ ID NO: 1 o SEQ ID NO: 6. La invención se refiere además a un proceso para preparar una masa en donde se usa un polipéptido como se describe en este documento y se prepara un producto horneado a partir de la masa.
MX2020014191A 2018-06-19 2019-06-18 Variantes de enzimas lipoliticas. MX2020014191A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18178445 2018-06-19
PCT/EP2019/065992 WO2019243312A1 (en) 2018-06-19 2019-06-18 Lipolytic enzyme variants

Publications (1)

Publication Number Publication Date
MX2020014191A true MX2020014191A (es) 2021-03-09

Family

ID=62712840

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020014191A MX2020014191A (es) 2018-06-19 2019-06-18 Variantes de enzimas lipoliticas.

Country Status (7)

Country Link
US (1) US20210115418A1 (es)
EP (1) EP3809852A1 (es)
CN (1) CN112292037B (es)
BR (1) BR112020025589A2 (es)
MX (1) MX2020014191A (es)
WO (1) WO2019243312A1 (es)
ZA (1) ZA202007357B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023116569A1 (en) 2021-12-21 2023-06-29 Novozymes A/S Composition comprising a lipase and a booster
WO2024121057A1 (en) 2022-12-05 2024-06-13 Novozymes A/S A composition for removing body grime

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990014423A1 (en) 1989-05-18 1990-11-29 The Infergene Company Microorganism transformation
CA2063592C (en) 1989-07-07 2003-01-21 Marco L. F. Giuseppin Process for preparing a protein by a fungus transformed by multicopy integration of an expression vector
DK76893D0 (es) 1993-06-28 1993-06-28 Novo Nordisk As
ATE238425T1 (de) 1993-07-23 2003-05-15 Dsm Nv Selektionmarker-genfreie rekombinante stämme: verfahren zur ihrer herstellung und die verwendung dieser stämme
DK0869167T4 (da) 1996-12-09 2010-03-08 Novozymes As Reduktion af phosphor-indeholdende bestanddele i spiseolier; som omfatter en stor mængde ikke-hydrerbart phosphor, ved anvendelse af en phospholipase, en phospholipase fra en trådsvamp, der har en phospholipase A og/eller B aktivitet
US6265186B1 (en) 1997-04-11 2001-07-24 Dsm N.V. Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
CN1169961C (zh) 1997-04-11 2004-10-06 Dsm公司 基因转变作为工具用于构建重组的工业化丝状真菌
AU736111C (en) 1997-12-22 2004-02-19 Dsm Ip Assets B.V. Expression cloning in filamentous fungi
AU4144999A (en) 1998-05-19 1999-12-06 Dsm N.V. Improved (in vivo) production of cephalosporins
CN1329667B (zh) 1998-10-05 2014-05-28 诺维信公司 在制备多肽的方法中有效的真菌转录激活因子
KR20010089672A (ko) 1998-12-22 2001-10-08 윌리암 로엘프 드 보에르 개선된 생체내 세팔로스포린 생산
ATE469223T1 (de) 2000-03-14 2010-06-15 Novozymes As Pilz transkriptionsaktivator zur verwendung in verfahren zur herstellung von polypeptiden
AU2003303934A1 (en) 2002-05-30 2004-09-09 Dsm Ip Assets B.V. Novel pectinases and uses thereof
US7465570B2 (en) * 2003-05-09 2008-12-16 Novozymes A/S Variant lipolytic enzymes
EP1799827A2 (en) 2004-10-12 2007-06-27 DSMIP Assets B.V. Fungal transcriptional activators useful in methods for producing a polypeptide
US7888489B2 (en) 2005-01-24 2011-02-15 Dsm Ip Assets B.V. Method for producing a compound of interest in a filamentous fungal cell
CA2630455A1 (en) 2005-11-29 2007-06-07 Dsm Ip Assets B.V. Dna binding site of a transcriptional activator useful in gene expression
WO2008000632A1 (en) 2006-06-29 2008-01-03 Dsm Ip Assets B.V. A method for achieving improved polypeptide expression
JP2011512809A (ja) 2008-02-29 2011-04-28 ディーエスエム アイピー アセッツ ビー．ブイ． 短鎖脂肪に対して特異性の高いリパーゼおよびその使用
AU2010241099A1 (en) 2009-04-22 2011-10-27 Dsm Ip Assets B.V. Process for the production of a recombinant polypeptide of interest
CN102428177B (zh) * 2009-05-19 2015-01-14 杜邦营养生物科学有限公司 提高面包耐码垛性的方法及其产品
EP2456872B1 (en) 2009-07-22 2017-08-30 DSM IP Assets B.V. Improved host cell for the production of a compound of interest
EA201300074A1 (ru) 2010-07-01 2013-06-28 ДСМ АйПи АССЕТС Б.В. Способ получения представляющего интерес соединения
CN104603273B (zh) 2012-03-12 2019-09-10 帝斯曼知识产权资产管理有限公司 重组系统
EP2875120B1 (en) 2012-07-19 2019-03-20 DSM IP Assets B.V. Amylase-deficient strain
DK3327112T3 (en) 2012-07-19 2020-05-04 Dsm Ip Assets Bv Agse-deficient stamme
EP3212768A1 (en) 2014-10-29 2017-09-06 Novozymes A/S Filamentous fungal double-mutant host cells
WO2018114912A1 (en) * 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Lipolytic enzyme variants
EP3596199A1 (en) 2017-03-13 2020-01-22 DSM IP Assets B.V. Zinc binuclear cluster transcriptional regulator-deficient strain

Also Published As

Publication number Publication date
WO2019243312A1 (en) 2019-12-26
US20210115418A1 (en) 2021-04-22
CN112292037B (zh) 2024-03-22
EP3809852A1 (en) 2021-04-28
ZA202007357B (en) 2023-01-25
BR112020025589A2 (pt) 2021-03-23
CN112292037A (zh) 2021-01-29

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