ID27054A - Perbaikan produksi sepalosporin di dalam organisme yang hidup - Google Patents

Perbaikan produksi sepalosporin di dalam organisme yang hidup

Info

Publication number
ID27054A
ID27054A IDW20002338A ID20002338A ID27054A ID 27054 A ID27054 A ID 27054A ID W20002338 A IDW20002338 A ID W20002338A ID 20002338 A ID20002338 A ID 20002338A ID 27054 A ID27054 A ID 27054A
Authority
ID
Indonesia
Prior art keywords
production
sepalosporin
improving
living organisms
host cell
Prior art date
Application number
IDW20002338A
Other languages
English (en)
Inventor
Maarten Nieboer
Roelof Ary Lans Bovenberg
Original Assignee
Dsm Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Nv filed Critical Dsm Nv
Publication of ID27054A publication Critical patent/ID27054A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IDW20002338A 1998-05-19 1999-05-19 Perbaikan produksi sepalosporin di dalam organisme yang hidup ID27054A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98201655 1998-05-19

Publications (1)

Publication Number Publication Date
ID27054A true ID27054A (id) 2001-02-22

Family

ID=8233737

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20002338A ID27054A (id) 1998-05-19 1999-05-19 Perbaikan produksi sepalosporin di dalam organisme yang hidup

Country Status (16)

Country Link
US (2) US6995003B1 (id)
EP (2) EP1078069B1 (id)
JP (1) JP2003527069A (id)
KR (1) KR100648480B1 (id)
CN (2) CN100390285C (id)
AT (1) ATE386123T1 (id)
AU (1) AU4144999A (id)
BR (1) BR9910532A (id)
DE (1) DE69938129D1 (id)
ES (1) ES2302379T3 (id)
ID (1) ID27054A (id)
MX (1) MXPA00011223A (id)
PL (1) PL344863A1 (id)
RU (1) RU2230790C2 (id)
WO (1) WO1999060102A2 (id)
ZA (1) ZA200006308B (id)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0011185D0 (en) * 2000-05-09 2000-06-28 Synpac Pharmaceuticals Limited Protein
CN1796537B (zh) * 2004-12-23 2010-09-08 华北制药集团有限责任公司 一种新的产黄青霉菌株以及利用此菌株发酵制备青霉素
US20060217971A1 (en) * 2005-03-28 2006-09-28 Tellabs Operations, Inc. Method and apparatus for modifying an encoded signal
ES2522622T3 (es) 2007-11-20 2014-11-17 Dsm Ip Assets B.V. Producción de ácido succínico en una célula eucariota
WO2009065779A1 (en) 2007-11-20 2009-05-28 Dsm Ip Assets B.V. Dicarboxylic acid production in a recombinant yeast
US20110318795A1 (en) 2007-11-20 2011-12-29 Verwaal Rene Dicarboxylic acid production in a filamentous fungus
EP2116136A1 (en) 2008-05-08 2009-11-11 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Novel phytases
US8735100B2 (en) 2009-03-17 2014-05-27 Nederlandse Organisatie Voor Toegepast -Natuurwetenschappelijk Onderzoek Tno Cellulose and ligno-cellulose active proteins
EP2419518A1 (en) 2009-04-15 2012-02-22 DSM IP Assets B.V. Dicarboxylic acid production process
UA108853C2 (uk) 2009-07-10 2015-06-25 Спосіб ферментації галактози
WO2011131667A1 (en) 2010-04-21 2011-10-27 Dsm Ip Assets B.V. Cell suitable for fermentation of a mixed sugar composition
EP2388331A1 (en) 2010-05-21 2011-11-23 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Constitutive promoter
WO2012049170A2 (en) 2010-10-13 2012-04-19 Dsm Ip Assets B.V. Pentose and glucose fermenting yeast cell
AR086471A1 (es) 2011-04-22 2013-12-18 Dsm Ip Assets Bv Celula de levadura capaz de convertir azucares que incluyen arabinosa y xilosa
AR087423A1 (es) 2011-08-04 2014-03-19 Dsm Ip Assets Bv Celula capaz de fermentar azucares pentosas
EP2554668A1 (en) 2011-08-04 2013-02-06 DSM IP Assets B.V. A pentose sugar fermenting cell
EP3444338A1 (en) 2012-01-23 2019-02-20 DSM IP Assets B.V. Diterpene production
PL2909305T3 (pl) 2012-10-16 2019-06-28 Dsm Ip Assets B.V. Komórki o ulepszonej konwersji pentozy
EP2772545A1 (en) 2013-03-01 2014-09-03 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Starch active proteins
US20160060660A1 (en) 2013-04-05 2016-03-03 Université Du Luxembourg Biotechnological production of itaconic acid
WO2014178717A1 (en) 2013-05-02 2014-11-06 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Novel organic acid pathway
AU2014273055A1 (en) 2013-05-31 2015-12-17 Dsm Ip Assets B.V. Microorganisms for diterpene production
EP3021689B1 (en) 2013-07-15 2021-03-24 DSM IP Assets B.V. Diterpene production
US20160185813A1 (en) 2013-07-31 2016-06-30 Dsm Ip Assets B.V. Recovery of steviol glycosides
CN107429273A (zh) 2015-02-16 2017-12-01 帝斯曼知识产权资产管理有限公司 用于在厌氧条件下生产衣康酸的方法
WO2016146711A1 (en) 2015-03-16 2016-09-22 Dsm Ip Assets B.V. Udp-glycosyltransferases
EP3274448B1 (en) 2015-03-23 2021-08-11 DSM IP Assets B.V. Udp-glycosyltransferases from solanum lycopersicum
BR112017021066B1 (pt) 2015-04-03 2022-02-08 Dsm Ip Assets B.V. Glicosídeos de esteviol, método para a produção de um glicosídeo de esteviol, composição, usos relacionados, gênero alimentício, alimento para animais e bebida
BR112017022488A2 (pt) 2015-04-21 2018-07-17 Dsm Ip Assets Bv produção microbiana de terpenoides
MY186983A (en) 2015-05-22 2021-08-26 Dsm Ip Assets Bv Acetate consuming yeast cell
CA2991651A1 (en) 2015-07-10 2017-01-19 Dsm Ip Assets B.V. Steviol glycoside composition
US20180230505A1 (en) 2015-08-13 2018-08-16 Dsm Ip Assets B.V. Steviol glycoside transport
WO2017050652A1 (en) 2015-09-25 2017-03-30 Dsm Ip Assets B.V. Asparaginase
WO2017060318A2 (en) 2015-10-05 2017-04-13 Dsm Ip Assets B.V. Kaurenoic acid hydroxylases
WO2017060195A1 (en) 2015-10-06 2017-04-13 Dsm Ip Assets B.V. Eukaryotic cell with increased production of fermentation product
BR112018013376A2 (pt) 2015-12-30 2018-12-18 Dsm Ip Assets Bv hidrólise enzimática parcial de triacilgliceróis
PE20181403A1 (es) 2015-12-30 2018-09-07 Dsm Ip Assets Bv Hidrolisis enzimatica parcial de triacilgliceroles
WO2017167847A1 (en) 2016-03-31 2017-10-05 Dsm Ip Assets B.V. Production of milk with low lactose content
EP3435771A1 (en) 2016-03-31 2019-02-06 DSM IP Assets B.V. Enzyme composition and preparation of a dairy product with improved properties
WO2017167849A1 (en) 2016-03-31 2017-10-05 Dsm Ip Assets B.V. Enzyme composition and preparation of a dairy product with improved properties
CA3027448A1 (en) 2016-06-14 2017-12-21 Dsm Ip Assets B.V. Recombinant yeast cell
CN109689864B (zh) 2016-07-13 2023-04-04 帝斯曼知识产权资产管理有限公司 苹果酸脱氢酶
CN109563118A (zh) 2016-08-09 2019-04-02 帝斯曼知识产权资产管理有限公司 甜菊醇糖苷的结晶
US20190169220A1 (en) 2016-08-09 2019-06-06 Dsm Ip Assets B.V. Crystallization of steviol glycosides
EP3504336A1 (en) 2016-08-26 2019-07-03 Lesaffre et Compagnie Improved production of itaconic acid
WO2018073107A1 (en) 2016-10-19 2018-04-26 Dsm Ip Assets B.V. Eukaryotic cell comprising xylose isomerase
EP3998337A1 (en) 2016-10-27 2022-05-18 DSM IP Assets B.V. Geranylgeranyl pyrophosphate synthases
CN110072995B (zh) 2016-12-08 2024-05-10 帝斯曼知识产权资产管理有限公司 贝壳杉烯酸羟化酶
US10918113B2 (en) 2016-12-21 2021-02-16 Dsm Ip Assets B.V. Lipolytic enzyme variants
WO2018114912A1 (en) 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Lipolytic enzyme variants
WO2018114938A1 (en) 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Lipolytic enzyme variants
CA3046153A1 (en) 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Lipolytic enzyme variants
WO2018114995A1 (en) 2016-12-22 2018-06-28 Dsm Ip Assets B.V. Fermentation process for producing steviol glycosides
BR112019025777A2 (pt) 2017-06-13 2020-06-30 Dsm Ip Assets B.V. célula de levedura recombinante
EP3645714B1 (en) 2017-06-27 2022-08-31 DSM IP Assets B.V. Udp-glycosyltransferases
EP3688177A1 (en) 2017-09-26 2020-08-05 DSM IP Assets B.V. Acetic acid consuming strain
EP3533878A1 (en) 2018-02-28 2019-09-04 Dutch DNA Biotech B.V. Process for producing citramalic acid employing aspergillus
MX2020014191A (es) 2018-06-19 2021-03-09 Dsm Ip Assets Bv Variantes de enzimas lipoliticas.
AU2021367159A1 (en) 2020-10-22 2023-05-04 Cargill, Incorporated Microorganisms for diterpene production
AU2022297881A1 (en) 2021-06-24 2024-01-18 Fonterra Co-Operative Group Limited Recombinant beta-lactoglobulin
CN117940570A (zh) 2021-07-12 2024-04-26 丹尼斯科美国公司 重组酵母细胞
EP4370690A1 (en) 2021-07-12 2024-05-22 Danisco Us Inc Recombinant yeast cell
MX2024000511A (es) 2021-07-12 2024-03-11 Danisco Us Inc Celula de levadura recombinante.
MX2024000514A (es) 2021-07-12 2024-03-11 Danisco Us Inc Celula de levadura recombinante.
WO2023285297A1 (en) 2021-07-12 2023-01-19 Dsm Ip Assets B.V. Recombinant yeast cell
WO2023285280A1 (en) 2021-07-12 2023-01-19 Dsm Ip Assets B.V. Recombinant yeast cell
CN118215740A (zh) 2021-11-04 2024-06-18 丹尼斯科美国公司 用于生产乙醇的方法和重组酵母细胞
CN118176296A (zh) 2021-11-04 2024-06-11 丹尼斯科美国公司 重组酵母细胞
EP4426823A1 (en) 2021-11-04 2024-09-11 Danisco Us Inc Variant polypeptide and recombinant yeast cell
CA3237662A1 (en) 2021-11-09 2023-05-19 Amgen Inc. Production of therapeutic proteins
WO2023222614A1 (en) 2022-05-16 2023-11-23 Dsm Ip Assets B.V. Lipolytic enzyme variants

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4003894A (en) 1971-08-17 1977-01-18 Gist-Brocades N.V. Preparation of 7-substituted amino-desacetoxycephalosporanic acid compounds
PT83746B (pt) 1985-11-15 1988-08-17 Gist Brocades Nv Processo para a preparacao de novos biocatalisadores imobilizados e para a producao de etanol por fermentacao
US5070020A (en) * 1988-05-09 1991-12-03 Eli Lilly And Company Recombinant dna expression vectors and dna compounds that encode deacetoxycephalosporin c synthetase
US5082772A (en) 1988-10-24 1992-01-21 Eli Lilly And Company Process for preparing deacetylcephalosporin c
PT97116B (pt) * 1990-03-23 1998-10-30 Gist Brocades Nv Processo para modular a producao de metabolitos secundarios nomeadamente derivados de beta-lactama
US5318896A (en) 1991-09-11 1994-06-07 Merck & Co., Inc. Recombinant expandase bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid (7-ADCA)
ES2198410T3 (es) 1993-07-23 2004-02-01 Dsm Ip Assets B.V. Cepas recombinantes de hongos filamentosos libres de gen marcador de seleccion: un metodo para obtener dichas cepas y su utilizacion.
HU219259B (en) 1993-07-30 2001-03-28 Gist Brocades Bv Process for the efficient production of 7-adca via 2-(carboxyethylthio)acetyl-7-adca and 3-(carboxymethylthio)propionyl-7-adca, recombinant dna vectrors and transformed host cells
ES2194873T3 (es) * 1993-07-30 2003-12-01 Dsm Ip Assets Bv Procedimiento para la produccion eficaz de 7-adca a traves de 3-(carboxietil)propionil-7-adca.
WO1997020053A2 (en) * 1995-11-27 1997-06-05 Gist-Brocades B.V. Improved process for the production of semi-synthetic cephalosporins via expandase activity on penicillin g
WO1998002551A2 (en) 1996-07-16 1998-01-22 Gist-Brocades B.V. Process for the production of adipoyl cephalosporins

Also Published As

Publication number Publication date
DE69938129D1 (de) 2008-03-27
PL344863A1 (en) 2001-11-19
US20060127972A1 (en) 2006-06-15
KR100648480B1 (ko) 2006-11-24
ES2302379T3 (es) 2008-07-01
CN100390285C (zh) 2008-05-28
WO1999060102A2 (en) 1999-11-25
CN1301303A (zh) 2001-06-27
MXPA00011223A (es) 2002-04-17
EP1078069A2 (en) 2001-02-28
ZA200006308B (en) 2001-05-23
EP1953230A1 (en) 2008-08-06
JP2003527069A (ja) 2003-09-16
WO1999060102A3 (en) 2000-02-03
BR9910532A (pt) 2001-10-16
KR20010025039A (ko) 2001-03-26
CN101353660A (zh) 2009-01-28
US6995003B1 (en) 2006-02-07
RU2230790C2 (ru) 2004-06-20
EP1078069B1 (en) 2008-02-13
ATE386123T1 (de) 2008-03-15
AU4144999A (en) 1999-12-06

Similar Documents

Publication Publication Date Title
ID27054A (id) Perbaikan produksi sepalosporin di dalam organisme yang hidup
ATE450605T1 (de) Phytase enzyme, dafür kodierende nukleinsäuren, und solche enthaltende vectoren und wirtszellen
ATE442453T1 (de) Verfahren zur herstellung von l-aminosäure oder nucleinsäure unter verwendung von mikroorganismen
ATE338139T1 (de) Herstellung von 3-hydroxypropionsäure in rekombinanten organismen
MXPA03000507A (es) Enzima de citocromo p450 asociada con la sintesis de grupos delta12-epoxi en acidos grasos de plantas..
JP6473175B2 (ja) ジカルボニル還元酵素突然変異体及びその応用
BR0014662A (pt) Enzimas as quais desidratam glicerol
AU6296400A (en) Method for preparing 1,3-propanediol by a recombinant micro-organism in the absence of coenzyme b12 or one of its precursors
FI924461A0 (fi) Hybridjaest, som innehaoller dna-sekvenser, som kodar foer xylosreduktas-och xylitoldehydrogenasenzymer
EP1302544A4 (en) MEDIUM ADDITIVES AND MEDIA FOR ANIMAL CELL CULTURES (11/06/02)
HUP9904302A2 (hu) Aciltranszferáz enzim és az aciltranszferázt kódoló gén
AU2001276036A1 (en) Use of cyp52a2a promoter to increase gene expression in yeast
ES2165276B1 (es) Procedimiento biotecnologico para la produccion de acido 7-aminocefal osporanico (7-adca) y compuestos de sintesis intermedios particularmente penicilina n y desacetoxicefalosporina c (daoc)
BR9909012A (pt) Enzima para oxidação de fenol purificada, polinucleotìdeo isolado, vetor de expressão, célula hospedeira, processos para produzir uma enzima para oxidação de fenol e para produzir uma célula hospedeira, cultura substancialmente pura, e, composição de enzima
WO2006093998A3 (en) Process and genes for expression and over-expression of active [fefe] hydrogenases
AU8404701A (en) Butinol I esterase
FR2801900B1 (fr) Methode de production de cellules animales adherentes
WO2003060092A3 (en) Modified fatty acid hydroxylase protein and genes
JP2007195453A (ja) グリセロールキナーゼ改変体
Kaiser The design of peptides and proteins
CN102884180A (zh) 重组胆红素氧化酶及其生产方法
WO2002022527A3 (en) Design and production of mutant 2,5-diketo-d-gluconic acid reductase enzymes with altered cofactor dependency
Wu et al. Redesign of protein function: a semisynthetic selenoenzyme
WO2002070666A3 (en) Compositions and methods for regulating autolytic processes in bacteria