MX2024000511A - Celula de levadura recombinante. - Google Patents

Celula de levadura recombinante.

Info

Publication number
MX2024000511A
MX2024000511A MX2024000511A MX2024000511A MX2024000511A MX 2024000511 A MX2024000511 A MX 2024000511A MX 2024000511 A MX2024000511 A MX 2024000511A MX 2024000511 A MX2024000511 A MX 2024000511A MX 2024000511 A MX2024000511 A MX 2024000511A
Authority
MX
Mexico
Prior art keywords
protein
nucleic acid
acid sequence
yeast cell
sequence encoding
Prior art date
Application number
MX2024000511A
Other languages
English (en)
Inventor
Sergio Luis Rossell-Aragort
Mickel Leonardus August Jansen
Van Lutz Ingrid Maria Vugt-
Jozef Petrus Johannes Schmitz
Rij Evert Tjeerd Van
Bruijn Hans Marinus Charles Johannes De
Phillip E Bureman
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Publication of MX2024000511A publication Critical patent/MX2024000511A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Una célula de levadura recombinante que expresa funcionalmente: - una secuencia de ácido nucleico que codifica una proteína que tiene actividad glicerol deshidrogenasa; - una secuencia de ácido nucleico que codifica una proteína que tiene actividad dihidroxiacetona cinasa; y - una secuencia de ácido nucleico que codifica una proteína que tiene actividad transportadora de glicerol, en donde la expresión de la secuencia de ácido nucleico que codifica la proteína que tiene actividad transportadora de glicerol está bajo el control de un promotor (el "promotor GT"), promotor GT que tiene una relación de expresión anaerobia/aerobia para el transportador de glicerol de 2 o más. y un proceso para la producción de etanol usando las células de levadura recombinantes.
MX2024000511A 2021-07-12 2022-07-07 Celula de levadura recombinante. MX2024000511A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163220905P 2021-07-12 2021-07-12
EP21185147 2021-07-12
PCT/EP2022/068983 WO2023285294A1 (en) 2021-07-12 2022-07-07 Recombinant yeast cell

Publications (1)

Publication Number Publication Date
MX2024000511A true MX2024000511A (es) 2024-03-11

Family

ID=82701796

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2024000511A MX2024000511A (es) 2021-07-12 2022-07-07 Celula de levadura recombinante.

Country Status (3)

Country Link
EP (1) EP4370692A1 (es)
MX (1) MX2024000511A (es)
WO (1) WO2023285294A1 (es)

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990014423A1 (en) 1989-05-18 1990-11-29 The Infergene Company Microorganism transformation
JP3273609B2 (ja) 1989-07-07 2002-04-08 ユニリーバー・ナームローゼ・ベンノートシヤープ 発現ベクターのマルチコピー組込みにより形質転換した真菌による蛋白質の製法
ES2198410T3 (es) 1993-07-23 2004-02-01 Dsm Ip Assets B.V. Cepas recombinantes de hongos filamentosos libres de gen marcador de seleccion: un metodo para obtener dichas cepas y su utilizacion.
US6265186B1 (en) 1997-04-11 2001-07-24 Dsm N.V. Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
PL336345A1 (en) 1997-04-11 2000-06-19 Dsm Nv Genic conversion as a tool for constructing recombined filiform fungi
ID27054A (id) 1998-05-19 2001-02-22 Dsm Nv Perbaikan produksi sepalosporin di dalam organisme yang hidup
EP1141372A2 (en) 1998-12-22 2001-10-10 Dsm N.V. Improved in vivo production of cephalosporins
EP2277989A1 (en) 2009-07-24 2011-01-26 Technische Universiteit Delft Fermentative glycerol-free ethanol production
US9988649B2 (en) * 2011-11-30 2018-06-05 Dsm Ip Assets B.V. Yeast strains engineered to produce ethanol from acetic acid and glycerol
WO2013144257A1 (en) 2012-03-27 2013-10-03 Dsm Ip Assets B.V. Cloning method
WO2014081803A1 (en) 2012-11-20 2014-05-30 Mascoma Corporation An electron consuming ethanol production pathway to displace glycerol formation in s. cerevisiae
EA201591294A1 (ru) 2013-02-22 2016-01-29 Технише Университет Делфт Рекомбинантный микроорганизм для применения в способе с повышенным выходом продукта
AR097479A1 (es) 2013-08-29 2016-03-16 Dsm Ip Assets Bv Células convertidoras de glicerol y ácido acético con un transporte de glicerol mejorado
AR097480A1 (es) 2013-08-29 2016-03-16 Dsm Ip Assets Bv Células de levadura convertidoras de glicerol y ácido acético con una conversión de ácido acético mejorada
EP3122876B1 (en) 2014-03-28 2020-11-25 Danisco US Inc. Altered host cell pathway for improved ethanol production
EP3242949B1 (en) 2015-01-06 2021-11-03 DSM IP Assets B.V. A crispr-cas system for a yeast host cell
CA3027448A1 (en) 2016-06-14 2017-12-21 Dsm Ip Assets B.V. Recombinant yeast cell
CA3045740A1 (en) 2016-12-23 2018-06-28 Dsm Ip Assets B.V. Improved glycerol free ethanol production
US20200024619A1 (en) 2017-03-21 2020-01-23 Dsm Ip Assets B.V. Improved glycerol free ethanol production
BR112019025777A2 (pt) 2017-06-13 2020-06-30 Dsm Ip Assets B.V. célula de levedura recombinante
US20200283805A1 (en) 2017-09-26 2020-09-10 Dsm Ip Assets B.V. Improved process for ethanol production
US20210380989A1 (en) * 2018-12-07 2021-12-09 Lallemand Hungary Liquidity Management Llc Modulation of nadph generation by recombinant yeast host cell during fermentation

Also Published As

Publication number Publication date
WO2023285294A1 (en) 2023-01-19
EP4370692A1 (en) 2024-05-22

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