AR097479A1 - Células convertidoras de glicerol y ácido acético con un transporte de glicerol mejorado - Google Patents

Células convertidoras de glicerol y ácido acético con un transporte de glicerol mejorado

Info

Publication number
AR097479A1
AR097479A1 ARP140103221A ARP140103221A AR097479A1 AR 097479 A1 AR097479 A1 AR 097479A1 AR P140103221 A ARP140103221 A AR P140103221A AR P140103221 A ARP140103221 A AR P140103221A AR 097479 A1 AR097479 A1 AR 097479A1
Authority
AR
Argentina
Prior art keywords
glycerol
seq
sequences encoding
acetic acid
improved
Prior art date
Application number
ARP140103221A
Other languages
English (en)
Inventor
Klaassen Paul
Willem Antonius Hartman Wouter
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of AR097479A1 publication Critical patent/AR097479A1/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/461—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from fish
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
    • C12P7/10—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate substrate containing cellulosic material
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Una célula que fue modificada genéticamente que comprende: a) una o más secuencias de nucleótidos que codifican una glicerol deshidrogenasa (E.C. 1.1.1.6); b) una o más secuencias de nucleótidos que codifican una dihidroxiacetona quinasa (E.C. 2.7.1.28 o E.C. 2.7.1.29); y c) una o más secuencias de nucleótidos que codifican un transportador de glicerol. Reivindicación 3: Una célula de acuerdo con la reivindicación 1 ó 2, caracterizada porque la célula comprende una o más secuencias de ácidos nucleicos que codifican un transportador de glicerol heterólogo representado por la SEQ ID Nº 31 o un homólogo funcional de la SEQ ID Nº 31 que tiene una identidad de secuencia de por lo menos un 60% con la SEQ ID Nº 31. Reivindicación 4: Una célula de acuerdo con la reivindicación 1 ó 2, caracterizada porque la célula comprende una o más secuencias de ácidos nucleicos que codifican un transportador de glicerol heterélogo representado por la SEQ ID Nº 29 o un homólogo funcional de la SEQ ID Nº 29 que tiene una identidad de secuencia de por lo menos un 50% con la SEQ ID Nº 29.
ARP140103221A 2013-08-29 2014-08-27 Células convertidoras de glicerol y ácido acético con un transporte de glicerol mejorado AR097479A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13182225 2013-08-29

Publications (1)

Publication Number Publication Date
AR097479A1 true AR097479A1 (es) 2016-03-16

Family

ID=49036505

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP140103221A AR097479A1 (es) 2013-08-29 2014-08-27 Células convertidoras de glicerol y ácido acético con un transporte de glicerol mejorado

Country Status (2)

Country Link
AR (1) AR097479A1 (es)
WO (1) WO2015028583A2 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3169768B1 (de) * 2014-07-14 2018-09-26 Jacobs University Bremen GmbH Gentechnisch veränderte hefe mit verbessertem glycerol-katabolismus
ES2864715T3 (es) * 2014-12-19 2021-10-14 Dsm Ip Assets Bv Proceso de fermentación con conversión de glicerol y ácido acético mejorada
MY186983A (en) 2015-05-22 2021-08-26 Dsm Ip Assets Bv Acetate consuming yeast cell
WO2017060195A1 (en) 2015-10-06 2017-04-13 Dsm Ip Assets B.V. Eukaryotic cell with increased production of fermentation product
US10913928B2 (en) 2016-12-20 2021-02-09 Dsm Ip Assets B.V. Yeast strains for ethanol production
CA3045740A1 (en) 2016-12-23 2018-06-28 Dsm Ip Assets B.V. Improved glycerol free ethanol production
US20200024619A1 (en) * 2017-03-21 2020-01-23 Dsm Ip Assets B.V. Improved glycerol free ethanol production
US20200377559A1 (en) * 2017-03-24 2020-12-03 Danisco Us Inc Reduction of acetate and glycerol in modified yeast having an exogenous ethanol-producing pathway
EP3688177A1 (en) * 2017-09-26 2020-08-05 DSM IP Assets B.V. Acetic acid consuming strain
CN111727196A (zh) * 2017-10-24 2020-09-29 丹尼斯科美国公司 具有改善的醇生产的酵母
WO2021089877A1 (en) 2019-11-08 2021-05-14 Dsm Ip Assets B.V. Process for producing ethanol
CN117795089A (zh) 2021-06-07 2024-03-29 诺维信公司 用于改善的乙醇发酵的工程化微生物
WO2023285280A1 (en) 2021-07-12 2023-01-19 Dsm Ip Assets B.V. Recombinant yeast cell
MX2024000514A (es) 2021-07-12 2024-03-11 Danisco Us Inc Celula de levadura recombinante.
CN117940570A (zh) 2021-07-12 2024-04-26 丹尼斯科美国公司 重组酵母细胞
EP4370690A1 (en) 2021-07-12 2024-05-22 Danisco Us Inc Recombinant yeast cell
MX2024000511A (es) 2021-07-12 2024-03-11 Danisco Us Inc Celula de levadura recombinante.
WO2023285297A1 (en) 2021-07-12 2023-01-19 Dsm Ip Assets B.V. Recombinant yeast cell
CN118176296A (zh) 2021-11-04 2024-06-11 丹尼斯科美国公司 重组酵母细胞

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008006037A2 (en) * 2006-07-06 2008-01-10 Integrated Genomics, Inc. Compositions and methods for enhancing glycerol utilization
WO2010015122A1 (en) * 2008-08-06 2010-02-11 Tianjin University Yeast strains and methods for making and using such yeast strains
WO2010019882A1 (en) * 2008-08-15 2010-02-18 Edeniq, Inc. Genetically-engineered yeast and methods of making and using
US20110250664A1 (en) * 2010-04-08 2011-10-13 Tianjin University Yeast having improved ethanol yield
WO2011132890A2 (ko) * 2010-04-19 2011-10-27 고려대학교 산학협력단 바이오 에탄올 생산 향상용 형질전환체 및 그 균주를 이용한 에탄올 생성방법
WO2011149353A1 (en) * 2010-05-27 2011-12-01 C5 Yeast Company B.V. Yeast strains engineered to produce ethanol from acetic acid and glycerol
ES2532508T3 (es) * 2010-11-18 2015-03-27 Dsm Ip Assets B.V. Cepas de levaduras manipuladas para producir etanol a partir de glicerol
US9988649B2 (en) * 2011-11-30 2018-06-05 Dsm Ip Assets B.V. Yeast strains engineered to produce ethanol from acetic acid and glycerol

Also Published As

Publication number Publication date
WO2015028583A2 (en) 2015-03-05
WO2015028583A3 (en) 2015-04-23

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