AR097479A1 - GLYCEROL AND ACETIC ACID CONVERTER CELLS WITH AN IMPROVED GLYCEROL TRANSPORT - Google Patents
GLYCEROL AND ACETIC ACID CONVERTER CELLS WITH AN IMPROVED GLYCEROL TRANSPORTInfo
- Publication number
- AR097479A1 AR097479A1 ARP140103221A ARP140103221A AR097479A1 AR 097479 A1 AR097479 A1 AR 097479A1 AR P140103221 A ARP140103221 A AR P140103221A AR P140103221 A ARP140103221 A AR P140103221A AR 097479 A1 AR097479 A1 AR 097479A1
- Authority
- AR
- Argentina
- Prior art keywords
- glycerol
- seq
- sequences encoding
- acetic acid
- improved
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/461—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from fish
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
- C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
- C12P7/10—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate substrate containing cellulosic material
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Una célula que fue modificada genéticamente que comprende: a) una o más secuencias de nucleótidos que codifican una glicerol deshidrogenasa (E.C. 1.1.1.6); b) una o más secuencias de nucleótidos que codifican una dihidroxiacetona quinasa (E.C. 2.7.1.28 o E.C. 2.7.1.29); y c) una o más secuencias de nucleótidos que codifican un transportador de glicerol. Reivindicación 3: Una célula de acuerdo con la reivindicación 1 ó 2, caracterizada porque la célula comprende una o más secuencias de ácidos nucleicos que codifican un transportador de glicerol heterólogo representado por la SEQ ID Nº 31 o un homólogo funcional de la SEQ ID Nº 31 que tiene una identidad de secuencia de por lo menos un 60% con la SEQ ID Nº 31. Reivindicación 4: Una célula de acuerdo con la reivindicación 1 ó 2, caracterizada porque la célula comprende una o más secuencias de ácidos nucleicos que codifican un transportador de glicerol heterélogo representado por la SEQ ID Nº 29 o un homólogo funcional de la SEQ ID Nº 29 que tiene una identidad de secuencia de por lo menos un 50% con la SEQ ID Nº 29.A cell that was genetically modified comprising: a) one or more nucleotide sequences encoding a glycerol dehydrogenase (E.C. 1.1.1.6); b) one or more nucleotide sequences encoding a dihydroxyacetone kinase (E.C. 2.7.1.28 or E.C. 2.7.1.29); and c) one or more nucleotide sequences encoding a glycerol transporter. Claim 3: A cell according to claim 1 or 2, characterized in that the cell comprises one or more nucleic acid sequences encoding a heterologous glycerol transporter represented by SEQ ID No. 31 or a functional homologue of SEQ ID No. 31 having a sequence identity of at least 60% with SEQ ID No. 31. Claim 4: A cell according to claim 1 or 2, characterized in that the cell comprises one or more nucleic acid sequences encoding a transporter of heterologous glycerol represented by SEQ ID No. 29 or a functional counterpart of SEQ ID No. 29 that has a sequence identity of at least 50% with SEQ ID No. 29.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13182225 | 2013-08-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR097479A1 true AR097479A1 (en) | 2016-03-16 |
Family
ID=49036505
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP140103221A AR097479A1 (en) | 2013-08-29 | 2014-08-27 | GLYCEROL AND ACETIC ACID CONVERTER CELLS WITH AN IMPROVED GLYCEROL TRANSPORT |
Country Status (2)
Country | Link |
---|---|
AR (1) | AR097479A1 (en) |
WO (1) | WO2015028583A2 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE112015003261A5 (en) * | 2014-07-14 | 2017-04-27 | Jacobs University Bremen Ggmbh | Genetically modified yeast with improved glycerol catabolism |
PL3234161T3 (en) * | 2014-12-19 | 2021-10-25 | Dsm Ip Assets B.V. | Fermentation process with improved glycerol and acetic acid conversion |
PL3298133T3 (en) | 2015-05-22 | 2020-03-31 | Dsm Ip Assets B.V. | Acetate consuming yeast cell |
WO2017060195A1 (en) | 2015-10-06 | 2017-04-13 | Dsm Ip Assets B.V. | Eukaryotic cell with increased production of fermentation product |
CN110088288B (en) | 2016-12-20 | 2023-08-29 | 帝斯曼知识产权资产管理有限公司 | Improved yeast strains for ethanol production |
EP3559220A1 (en) | 2016-12-23 | 2019-10-30 | DSM IP Assets B.V. | Improved glycerol free ethanol production |
WO2018172328A1 (en) * | 2017-03-21 | 2018-09-27 | Dsm Ip Assets B.V. | Improved glycerol free ethanol production |
BR112019019701A2 (en) * | 2017-03-24 | 2020-07-14 | Danisco Us Inc. | reduction of acetate and glycerol in modified yeast that has an exogenous ethanol production path |
CA3074001A1 (en) * | 2017-09-26 | 2019-04-04 | Dsm Ip Assets B.V. | Acetic acid consuming strain |
WO2019083879A1 (en) * | 2017-10-24 | 2019-05-02 | Danisco Us Inc | Yeast with improved alcohol production |
BR112022007870A2 (en) | 2019-11-08 | 2022-07-12 | Dsm Ip Assets Bv | PROCESS TO PRODUCE ETHANOL |
EP4352241A1 (en) | 2021-06-07 | 2024-04-17 | Novozymes A/S | Engineered microorganism for improved ethanol fermentation |
WO2023285279A1 (en) | 2021-07-12 | 2023-01-19 | Dsm Ip Assets B.V. | Recombinant yeast cell |
WO2023285297A1 (en) | 2021-07-12 | 2023-01-19 | Dsm Ip Assets B.V. | Recombinant yeast cell |
EP4370690A1 (en) | 2021-07-12 | 2024-05-22 | Danisco Us Inc | Recombinant yeast cell |
EP4370689A1 (en) | 2021-07-12 | 2024-05-22 | Danisco Us Inc | Recombinant yeast cell |
WO2023285282A1 (en) | 2021-07-12 | 2023-01-19 | Dsm Ip Assets B.V. | Recombinant yeast cell |
EP4370692A1 (en) | 2021-07-12 | 2024-05-22 | Danisco Us Inc | Recombinant yeast cell |
WO2023079050A1 (en) | 2021-11-04 | 2023-05-11 | Dsm Ip Assets B.V. | Recombinant yeast cell |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2041267A4 (en) * | 2006-07-06 | 2009-09-02 | Integrated Genomics Inc | Compositions and methods for enhancing glycerol utilization |
WO2010015122A1 (en) * | 2008-08-06 | 2010-02-11 | Tianjin University | Yeast strains and methods for making and using such yeast strains |
US20110136195A1 (en) * | 2008-08-15 | 2011-06-09 | Edeniq, Inc. | Genetically-engineered yeast and methods of making and using |
WO2011124146A1 (en) * | 2010-04-08 | 2011-10-13 | Tianjin University | Yeast having improved ethanol yield |
US8772000B2 (en) * | 2010-04-19 | 2014-07-08 | Korea University Research And Business Foundation | Transformant for enhancing bioethanol production, and method for producing ethanol by using said strain |
WO2011149353A1 (en) * | 2010-05-27 | 2011-12-01 | C5 Yeast Company B.V. | Yeast strains engineered to produce ethanol from acetic acid and glycerol |
CA2834053C (en) * | 2010-11-18 | 2019-03-26 | Dsm Ip Assets B.V. | Yeast strains engineered to produce ethanol from glycerol |
AU2012346662B2 (en) * | 2011-11-30 | 2016-07-28 | Danisco Us Inc. | Yeast strains engineered to produce ethanol from acetic acid and glycerol |
-
2014
- 2014-08-27 AR ARP140103221A patent/AR097479A1/en unknown
- 2014-08-29 WO PCT/EP2014/068325 patent/WO2015028583A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2015028583A2 (en) | 2015-03-05 |
WO2015028583A3 (en) | 2015-04-23 |
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