KR100648480B1 - 세팔로스포린의 개선된 생체내 생산 - Google Patents

세팔로스포린의 개선된 생체내 생산 Download PDF

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KR100648480B1
KR100648480B1 KR1020007012957A KR20007012957A KR100648480B1 KR 100648480 B1 KR100648480 B1 KR 100648480B1 KR 1020007012957 A KR1020007012957 A KR 1020007012957A KR 20007012957 A KR20007012957 A KR 20007012957A KR 100648480 B1 KR100648480 B1 KR 100648480B1
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expandase
host
apa
acid
host cell
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KR20010025039A (ko
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니에보에르마아르텐
보벤베르그로엘로프아리란스
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디에스엠 아이피 어셋츠 비.브이.
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020007012957A 1998-05-19 1999-05-19 세팔로스포린의 개선된 생체내 생산 Expired - Fee Related KR100648480B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98201655.2 1998-05-19
EP98201655 1998-05-19

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KR20010025039A KR20010025039A (ko) 2001-03-26
KR100648480B1 true KR100648480B1 (ko) 2006-11-24

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US (2) US6995003B1 (enExample)
EP (2) EP1078069B1 (enExample)
JP (1) JP2003527069A (enExample)
KR (1) KR100648480B1 (enExample)
CN (2) CN101353660A (enExample)
AT (1) ATE386123T1 (enExample)
AU (1) AU4144999A (enExample)
BR (1) BR9910532A (enExample)
DE (1) DE69938129D1 (enExample)
ES (1) ES2302379T3 (enExample)
ID (1) ID27054A (enExample)
MX (1) MXPA00011223A (enExample)
PL (1) PL344863A1 (enExample)
RU (1) RU2230790C2 (enExample)
WO (1) WO1999060102A2 (enExample)
ZA (1) ZA200006308B (enExample)

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EP3259361A1 (en) 2015-02-16 2017-12-27 DSM IP Assets B.V. Process for producing itaconic acid under anaerobic conditions
CA2979931A1 (en) 2015-03-16 2016-09-22 Dsm Ip Assets B.V. Udp-glycosyltransferases
CA2979957A1 (en) 2015-03-23 2016-09-29 Dsm Ip Assets B.V. Udp-glycosyltransferases from solanum lycopersicum
EP3718417B1 (en) 2015-04-03 2025-09-03 DSM IP Assets B.V. Steviol glycosides
CN107532135A (zh) 2015-04-21 2018-01-02 帝斯曼知识产权资产管理有限公司 萜类化合物的微生物生产
MY186983A (en) 2015-05-22 2021-08-26 Dsm Ip Assets Bv Acetate consuming yeast cell
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Publication number Publication date
CN101353660A (zh) 2009-01-28
JP2003527069A (ja) 2003-09-16
US20060127972A1 (en) 2006-06-15
ES2302379T3 (es) 2008-07-01
RU2230790C2 (ru) 2004-06-20
WO1999060102A3 (en) 2000-02-03
AU4144999A (en) 1999-12-06
EP1078069B1 (en) 2008-02-13
CN1301303A (zh) 2001-06-27
EP1078069A2 (en) 2001-02-28
ATE386123T1 (de) 2008-03-15
ZA200006308B (en) 2001-05-23
DE69938129D1 (de) 2008-03-27
EP1953230A1 (en) 2008-08-06
PL344863A1 (en) 2001-11-19
US6995003B1 (en) 2006-02-07
ID27054A (id) 2001-02-22
BR9910532A (pt) 2001-10-16
WO1999060102A2 (en) 1999-11-25
MXPA00011223A (es) 2002-04-17
CN100390285C (zh) 2008-05-28
KR20010025039A (ko) 2001-03-26

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