PL200225B1 - Sposób rekombinacyjnego wytwarzania polipeptydu heterologicznego - Google Patents
Sposób rekombinacyjnego wytwarzania polipeptydu heterologicznegoInfo
- Publication number
- PL200225B1 PL200225B1 PL353101A PL35310100A PL200225B1 PL 200225 B1 PL200225 B1 PL 200225B1 PL 353101 A PL353101 A PL 353101A PL 35310100 A PL35310100 A PL 35310100A PL 200225 B1 PL200225 B1 PL 200225B1
- Authority
- PL
- Poland
- Prior art keywords
- pro
- polypeptide
- fusion protein
- leu
- protein
- Prior art date
Links
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
- C12N9/506—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses derived from RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT136799 | 1999-08-09 | ||
| PCT/EP2000/007643 WO2001011057A1 (en) | 1999-08-09 | 2000-08-07 | Production of proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL353101A1 PL353101A1 (en) | 2003-10-20 |
| PL200225B1 true PL200225B1 (pl) | 2008-12-31 |
Family
ID=3512357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL353101A PL200225B1 (pl) | 1999-08-09 | 2000-08-07 | Sposób rekombinacyjnego wytwarzania polipeptydu heterologicznego |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US6936455B1 (https=) |
| EP (1) | EP1200604B1 (https=) |
| JP (1) | JP4820512B2 (https=) |
| KR (1) | KR20020026366A (https=) |
| CN (1) | CN1230543C (https=) |
| AT (1) | ATE335826T1 (https=) |
| AU (1) | AU775662B2 (https=) |
| CA (1) | CA2379571C (https=) |
| CZ (1) | CZ302366B6 (https=) |
| DE (1) | DE60029968T2 (https=) |
| ES (1) | ES2269173T3 (https=) |
| HK (1) | HK1047128B (https=) |
| HU (1) | HU230231B1 (https=) |
| IL (1) | IL147456A0 (https=) |
| MX (1) | MXPA02001424A (https=) |
| NO (1) | NO328339B1 (https=) |
| NZ (1) | NZ516869A (https=) |
| PL (1) | PL200225B1 (https=) |
| SK (1) | SK287488B6 (https=) |
| TR (1) | TR200200253T2 (https=) |
| WO (1) | WO2001011057A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR200200048T2 (tr) * | 1999-08-09 | 2002-04-22 | Biochemie Gesellschaft M.B.H. | Otoproteolitik klevaj vasıtasıyla proteinlerin üretimi. |
| ES2453048T3 (es) | 2004-03-30 | 2014-04-03 | Relypsa, Inc. | Polímeros de unión de ión y usos de los mismos |
| PL1874825T3 (pl) * | 2005-04-26 | 2011-04-29 | Boehringer Ingelheim Rcv Gmbh | Ligandy powinowactwa |
| AU2011253661B2 (en) * | 2005-04-26 | 2013-06-13 | Boehringer Ingelheim Rcv Gmbh & Co Kg | Production of recombinant proteins by autoproteolytic cleavage of a fusion protein |
| GB0508434D0 (en) * | 2005-04-26 | 2005-06-01 | Sandoz Ag | Organic compounds |
| GB0508435D0 (en) * | 2005-04-26 | 2005-06-01 | Sandoz Ag | Organic compounds |
| CN103069000A (zh) | 2010-08-31 | 2013-04-24 | 天野酶株式会社 | 使用了酶的蛋壳膜的溶解方法 |
| EP2684951A1 (en) | 2012-07-13 | 2014-01-15 | Sandoz Ag | Method for producing a recombinant protein of interest |
| EP2746390A1 (en) * | 2012-12-19 | 2014-06-25 | Sandoz Ag | Method for producing a recombinant protein of interest |
| EP2746391A1 (en) | 2012-12-19 | 2014-06-25 | Sandoz Ag | Method for producing a recombinant protein of interest |
| UY35874A (es) | 2013-12-12 | 2015-07-31 | Novartis Ag | Un proceso para la preparación de una composición de proteínas pegiladas |
| RU2619217C1 (ru) * | 2015-12-04 | 2017-05-12 | Федеральное государственное бюджетное учреждение "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГБУ "ГосНИИгенетика") | Температурочувствительный мутантный интеин для нерастворимой экспрессии предшественника целевого белка |
| CN114539425B (zh) * | 2022-02-25 | 2023-04-28 | 湖南中晟全肽生化有限公司 | 一种提高线性多肽生物表达的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4743679A (en) | 1986-02-24 | 1988-05-10 | Creative Biomolecules, Inc. | Process for producing human epidermal growth factor and analogs thereof |
| EP0321973B1 (de) * | 1987-12-23 | 1993-11-03 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Expression der viral kodierten Protease P2A des HRV2 |
| TW505697B (en) * | 1997-04-25 | 2002-10-11 | Sembiosys Genetics Inc | Method for cleavage of fusion proteins |
| DE59812768D1 (de) | 1997-08-22 | 2005-06-09 | Roche Diagnostics Gmbh | Autokatalytisch aktivierbare zymogene vorstufen von proteasen und deren verwendung |
| WO1999010483A2 (de) | 1997-08-22 | 1999-03-04 | Roche Diagnostics Gmbh | Autokatalytisch aktivierbare vorstufen von proteasen und deren verwendung |
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2000
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- 2000-08-07 CA CA2379571A patent/CA2379571C/en not_active Expired - Lifetime
- 2000-08-07 JP JP2001515842A patent/JP4820512B2/ja not_active Expired - Lifetime
- 2000-08-07 MX MXPA02001424A patent/MXPA02001424A/es unknown
- 2000-08-07 NZ NZ516869A patent/NZ516869A/en not_active IP Right Cessation
- 2000-08-07 AT AT00958389T patent/ATE335826T1/de active
- 2000-08-07 HK HK02107014.5A patent/HK1047128B/en not_active IP Right Cessation
- 2000-08-07 HU HU0202519A patent/HU230231B1/hu unknown
- 2000-08-07 CZ CZ20020481A patent/CZ302366B6/cs not_active IP Right Cessation
- 2000-08-07 KR KR1020027001666A patent/KR20020026366A/ko not_active Ceased
- 2000-08-07 SK SK185-2002A patent/SK287488B6/sk not_active IP Right Cessation
- 2000-08-07 CN CNB008114595A patent/CN1230543C/zh not_active Expired - Lifetime
- 2000-08-07 WO PCT/EP2000/007643 patent/WO2001011057A1/en not_active Ceased
- 2000-08-07 TR TR2002/00253T patent/TR200200253T2/xx unknown
- 2000-08-07 US US10/048,882 patent/US6936455B1/en not_active Expired - Lifetime
- 2000-08-07 EP EP00958389A patent/EP1200604B1/en not_active Expired - Lifetime
- 2000-08-07 AU AU69933/00A patent/AU775662B2/en not_active Expired
- 2000-08-07 ES ES00958389T patent/ES2269173T3/es not_active Expired - Lifetime
- 2000-08-07 IL IL14745600A patent/IL147456A0/xx unknown
- 2000-08-07 DE DE60029968T patent/DE60029968T2/de not_active Expired - Lifetime
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2002
- 2002-02-08 NO NO20020633A patent/NO328339B1/no not_active IP Right Cessation
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- 2005-04-05 US US11/099,302 patent/US20050186564A1/en not_active Abandoned
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