TR200200253T2 - Proteinlerin üretimi - Google Patents

Proteinlerin üretimi

Info

Publication number
TR200200253T2
TR200200253T2 TR2002/00253T TR200200253T TR200200253T2 TR 200200253 T2 TR200200253 T2 TR 200200253T2 TR 2002/00253 T TR2002/00253 T TR 2002/00253T TR 200200253 T TR200200253 T TR 200200253T TR 200200253 T2 TR200200253 T2 TR 200200253T2
Authority
TR
Turkey
Prior art keywords
heterologous polypeptide
npro
host cell
activity
coverage
Prior art date
Application number
TR2002/00253T
Other languages
English (en)
Turkish (tr)
Inventor
Stempfer G�Nter
Windisch J�Rg
Knauseder Franz
Original Assignee
Bio-Chemie Gesellschaft M.B.H.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio-Chemie Gesellschaft M.B.H. filed Critical Bio-Chemie Gesellschaft M.B.H.
Publication of TR200200253T2 publication Critical patent/TR200200253T2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
    • C12N9/506—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses derived from RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
TR2002/00253T 1999-08-09 2000-08-07 Proteinlerin üretimi TR200200253T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT136799 1999-08-09

Publications (1)

Publication Number Publication Date
TR200200253T2 true TR200200253T2 (tr) 2002-05-21

Family

ID=3512357

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/00253T TR200200253T2 (tr) 1999-08-09 2000-08-07 Proteinlerin üretimi

Country Status (21)

Country Link
US (2) US6936455B1 (https=)
EP (1) EP1200604B1 (https=)
JP (1) JP4820512B2 (https=)
KR (1) KR20020026366A (https=)
CN (1) CN1230543C (https=)
AT (1) ATE335826T1 (https=)
AU (1) AU775662B2 (https=)
CA (1) CA2379571C (https=)
CZ (1) CZ302366B6 (https=)
DE (1) DE60029968T2 (https=)
ES (1) ES2269173T3 (https=)
HK (1) HK1047128B (https=)
HU (1) HU230231B1 (https=)
IL (1) IL147456A0 (https=)
MX (1) MXPA02001424A (https=)
NO (1) NO328339B1 (https=)
NZ (1) NZ516869A (https=)
PL (1) PL200225B1 (https=)
SK (1) SK287488B6 (https=)
TR (1) TR200200253T2 (https=)
WO (1) WO2001011057A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200200048T2 (tr) * 1999-08-09 2002-04-22 Biochemie Gesellschaft M.B.H. Otoproteolitik klevaj vasıtasıyla proteinlerin üretimi.
ES2453048T3 (es) 2004-03-30 2014-04-03 Relypsa, Inc. Polímeros de unión de ión y usos de los mismos
PL1874825T3 (pl) * 2005-04-26 2011-04-29 Boehringer Ingelheim Rcv Gmbh Ligandy powinowactwa
AU2011253661B2 (en) * 2005-04-26 2013-06-13 Boehringer Ingelheim Rcv Gmbh & Co Kg Production of recombinant proteins by autoproteolytic cleavage of a fusion protein
GB0508434D0 (en) * 2005-04-26 2005-06-01 Sandoz Ag Organic compounds
GB0508435D0 (en) * 2005-04-26 2005-06-01 Sandoz Ag Organic compounds
CN103069000A (zh) 2010-08-31 2013-04-24 天野酶株式会社 使用了酶的蛋壳膜的溶解方法
EP2684951A1 (en) 2012-07-13 2014-01-15 Sandoz Ag Method for producing a recombinant protein of interest
EP2746390A1 (en) * 2012-12-19 2014-06-25 Sandoz Ag Method for producing a recombinant protein of interest
EP2746391A1 (en) 2012-12-19 2014-06-25 Sandoz Ag Method for producing a recombinant protein of interest
UY35874A (es) 2013-12-12 2015-07-31 Novartis Ag Un proceso para la preparación de una composición de proteínas pegiladas
RU2619217C1 (ru) * 2015-12-04 2017-05-12 Федеральное государственное бюджетное учреждение "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГБУ "ГосНИИгенетика") Температурочувствительный мутантный интеин для нерастворимой экспрессии предшественника целевого белка
CN114539425B (zh) * 2022-02-25 2023-04-28 湖南中晟全肽生化有限公司 一种提高线性多肽生物表达的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4743679A (en) 1986-02-24 1988-05-10 Creative Biomolecules, Inc. Process for producing human epidermal growth factor and analogs thereof
EP0321973B1 (de) * 1987-12-23 1993-11-03 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Expression der viral kodierten Protease P2A des HRV2
TW505697B (en) * 1997-04-25 2002-10-11 Sembiosys Genetics Inc Method for cleavage of fusion proteins
DE59812768D1 (de) 1997-08-22 2005-06-09 Roche Diagnostics Gmbh Autokatalytisch aktivierbare zymogene vorstufen von proteasen und deren verwendung
WO1999010483A2 (de) 1997-08-22 1999-03-04 Roche Diagnostics Gmbh Autokatalytisch aktivierbare vorstufen von proteasen und deren verwendung

Also Published As

Publication number Publication date
DE60029968D1 (de) 2006-09-21
HU230231B1 (hu) 2015-10-28
NO20020633L (no) 2002-04-05
US6936455B1 (en) 2005-08-30
IL147456A0 (en) 2002-08-14
NO328339B1 (no) 2010-02-01
ES2269173T3 (es) 2007-04-01
SK287488B6 (sk) 2010-11-08
CZ2002481A3 (cs) 2002-05-15
PL200225B1 (pl) 2008-12-31
AU6993300A (en) 2001-03-05
HUP0202519A2 (en) 2002-10-28
CZ302366B6 (cs) 2011-04-13
HK1047128A1 (en) 2003-02-07
CN1369014A (zh) 2002-09-11
EP1200604B1 (en) 2006-08-09
US20050186564A1 (en) 2005-08-25
HK1047128B (en) 2007-06-08
DE60029968T2 (de) 2006-12-21
NZ516869A (en) 2004-01-30
WO2001011057A1 (en) 2001-02-15
MXPA02001424A (es) 2002-08-12
SK1852002A3 (en) 2002-07-02
HUP0202519A3 (en) 2004-07-28
CA2379571C (en) 2011-03-29
PL353101A1 (en) 2003-10-20
NO20020633D0 (no) 2002-02-08
CN1230543C (zh) 2005-12-07
CA2379571A1 (en) 2001-02-15
JP4820512B2 (ja) 2011-11-24
JP2003506093A (ja) 2003-02-18
AU775662B2 (en) 2004-08-12
KR20020026366A (ko) 2002-04-09
EP1200604A1 (en) 2002-05-02
ATE335826T1 (de) 2006-09-15

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