PL128998B1 - Process for preparing novel 2-amino-3-benzoylphenylacetamides and their derivatives - Google Patents
Process for preparing novel 2-amino-3-benzoylphenylacetamides and their derivatives Download PDFInfo
- Publication number
- PL128998B1 PL128998B1 PL1980226919A PL22691980A PL128998B1 PL 128998 B1 PL128998 B1 PL 128998B1 PL 1980226919 A PL1980226919 A PL 1980226919A PL 22691980 A PL22691980 A PL 22691980A PL 128998 B1 PL128998 B1 PL 128998B1
- Authority
- PL
- Poland
- Prior art keywords
- amino
- solution
- mol
- added
- mixture
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7886079A | 1979-09-26 | 1979-09-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL226919A1 PL226919A1 (OSRAM) | 1982-02-01 |
| PL128998B1 true PL128998B1 (en) | 1984-03-31 |
Family
ID=22146633
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1980226919A PL128998B1 (en) | 1979-09-26 | 1980-09-25 | Process for preparing novel 2-amino-3-benzoylphenylacetamides and their derivatives |
Country Status (36)
| Country | Link |
|---|---|
| JP (1) | JPS5657751A (OSRAM) |
| KR (1) | KR840000763B1 (OSRAM) |
| AT (1) | AT374170B (OSRAM) |
| AU (1) | AU532359B2 (OSRAM) |
| BE (1) | BE885393A (OSRAM) |
| BR (1) | BR8006042A (OSRAM) |
| CA (1) | CA1128512A (OSRAM) |
| CH (1) | CH646138A5 (OSRAM) |
| CS (1) | CS227012B2 (OSRAM) |
| DE (1) | DE3035688A1 (OSRAM) |
| DK (1) | DK154136C (OSRAM) |
| EG (1) | EG15020A (OSRAM) |
| ES (2) | ES8200329A1 (OSRAM) |
| FI (1) | FI72967C (OSRAM) |
| FR (1) | FR2465710A1 (OSRAM) |
| GB (1) | GB2059963B (OSRAM) |
| GR (1) | GR70049B (OSRAM) |
| HK (1) | HK59383A (OSRAM) |
| HU (1) | HU183215B (OSRAM) |
| IE (1) | IE50268B1 (OSRAM) |
| IL (1) | IL60999A (OSRAM) |
| IN (3) | IN151313B (OSRAM) |
| IT (1) | IT1133823B (OSRAM) |
| KE (1) | KE3307A (OSRAM) |
| LU (1) | LU82797A1 (OSRAM) |
| MX (1) | MX7159E (OSRAM) |
| NL (1) | NL8005346A (OSRAM) |
| NO (1) | NO152128C (OSRAM) |
| NZ (1) | NZ195061A (OSRAM) |
| PH (1) | PH22628A (OSRAM) |
| PL (1) | PL128998B1 (OSRAM) |
| PT (1) | PT71839B (OSRAM) |
| SE (1) | SE448626B (OSRAM) |
| SG (1) | SG42983G (OSRAM) |
| YU (3) | YU41734B (OSRAM) |
| ZA (1) | ZA805476B (OSRAM) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL61945A (en) * | 1980-02-19 | 1984-09-30 | Robins Co Inc A H | 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them |
| US6646001B2 (en) | 1997-12-19 | 2003-11-11 | Alcon Manufacturing, Ltd. | Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension |
| US6066671A (en) * | 1997-12-19 | 2000-05-23 | Alcon Laboratories, Inc. | Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides |
| GB9727523D0 (en) | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
| AR030345A1 (es) * | 2000-08-14 | 2003-08-20 | Alcon Inc | Metodo de tratamiento de desordenes relacionados con angiogenesis |
| CN1274306C (zh) | 2001-09-03 | 2006-09-13 | 纽朗制药有限公司 | 包含加巴喷丁或其类似物和α－氨基酰胺的药物组合物及其止痛应用 |
| EP1438956A1 (en) | 2003-01-16 | 2004-07-21 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful as antimigraine agents |
| CZ301776B6 (cs) * | 2009-06-08 | 2010-06-16 | Farmak, A.S. | Postup prípravy 2-amino-3-benzoylfenylacetamidu (nepafenacu) s minimem vedlejších produktu |
| CN112794809B (zh) * | 2019-11-14 | 2023-12-29 | 南京济群医药科技股份有限公司 | 一种高纯度奈帕芬胺中间体的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1226344A (OSRAM) * | 1967-07-31 | 1971-03-24 | ||
| SE400966B (sv) * | 1975-08-13 | 1978-04-17 | Robins Co Inc A H | Forfarande for framstellning av 2-amino-3-(eller 5-)bensoyl-fenylettiksyror |
| IL61945A (en) * | 1980-02-19 | 1984-09-30 | Robins Co Inc A H | 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them |
-
1980
- 1980-09-04 ZA ZA00805476A patent/ZA805476B/xx unknown
- 1980-09-08 AU AU62116/80A patent/AU532359B2/en not_active Ceased
- 1980-09-08 IL IL60999A patent/IL60999A/xx unknown
- 1980-09-11 CS CS806196A patent/CS227012B2/cs unknown
- 1980-09-17 IE IE1946/80A patent/IE50268B1/en unknown
- 1980-09-20 EG EG80573A patent/EG15020A/xx active
- 1980-09-22 DE DE19803035688 patent/DE3035688A1/de active Granted
- 1980-09-22 GR GR62936A patent/GR70049B/el unknown
- 1980-09-22 BR BR8006042A patent/BR8006042A/pt unknown
- 1980-09-23 PH PH24613A patent/PH22628A/en unknown
- 1980-09-23 AT AT0474580A patent/AT374170B/de not_active IP Right Cessation
- 1980-09-24 SE SE8006668A patent/SE448626B/sv not_active IP Right Cessation
- 1980-09-24 LU LU82797A patent/LU82797A1/fr unknown
- 1980-09-24 FI FI803002A patent/FI72967C/fi not_active IP Right Cessation
- 1980-09-25 ES ES495329A patent/ES8200329A1/es not_active Expired
- 1980-09-25 YU YU2450/80A patent/YU41734B/xx unknown
- 1980-09-25 CH CH719180A patent/CH646138A5/fr not_active IP Right Cessation
- 1980-09-25 PL PL1980226919A patent/PL128998B1/pl unknown
- 1980-09-25 CA CA361,068A patent/CA1128512A/en not_active Expired
- 1980-09-25 NL NL8005346A patent/NL8005346A/nl not_active Application Discontinuation
- 1980-09-25 KR KR1019800003740A patent/KR840000763B1/ko not_active Expired
- 1980-09-25 PT PT71839A patent/PT71839B/pt unknown
- 1980-09-25 DK DK405780A patent/DK154136C/da not_active IP Right Cessation
- 1980-09-25 FR FR8020596A patent/FR2465710A1/fr active Granted
- 1980-09-25 GB GB8030955A patent/GB2059963B/en not_active Expired
- 1980-09-25 MX MX809050U patent/MX7159E/es unknown
- 1980-09-25 NO NO802834A patent/NO152128C/no unknown
- 1980-09-25 HU HU802347A patent/HU183215B/hu not_active IP Right Cessation
- 1980-09-25 BE BE0/202226A patent/BE885393A/fr not_active IP Right Cessation
- 1980-09-26 JP JP13415280A patent/JPS5657751A/ja active Granted
- 1980-09-26 IN IN1092/CAL/80A patent/IN151313B/en unknown
- 1980-09-26 IT IT24948/80A patent/IT1133823B/it active
- 1980-09-26 NZ NZ195061A patent/NZ195061A/en unknown
-
1981
- 1981-06-12 ES ES503019A patent/ES8204715A1/es not_active Expired
-
1982
- 1982-12-30 IN IN1508/CAL/82A patent/IN156254B/en unknown
- 1982-12-30 IN IN1509/CAL/82A patent/IN156255B/en unknown
-
1983
- 1983-03-28 YU YU730/83A patent/YU43305B/xx unknown
- 1983-03-28 YU YU731/83A patent/YU43306B/xx unknown
- 1983-07-19 SG SG42983A patent/SG42983G/en unknown
- 1983-07-21 KE KE3307A patent/KE3307A/xx unknown
- 1983-11-24 HK HK593/83A patent/HK59383A/xx unknown
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