PH30953A - Azithromycin dihydrate. - Google Patents

Azithromycin dihydrate.

Info

Publication number
PH30953A
PH30953A PH37189A PH37189A PH30953A PH 30953 A PH30953 A PH 30953A PH 37189 A PH37189 A PH 37189A PH 37189 A PH37189 A PH 37189A PH 30953 A PH30953 A PH 30953A
Authority
PH
Philippines
Prior art keywords
azithromycin dihydrate
azithromycin
dihydrate
Prior art date
Application number
PH37189A
Other languages
English (en)
Inventor
Allen Douglas John Meldrum
Nepvoux Kevin Michael
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22202456&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PH30953(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of PH30953A publication Critical patent/PH30953A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PH37189A 1987-07-09 1988-07-07 Azithromycin dihydrate. PH30953A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/001612 WO1989000576A1 (en) 1987-07-09 1987-07-09 Azithromycin dihydrate

Publications (1)

Publication Number Publication Date
PH30953A true PH30953A (en) 1997-12-23

Family

ID=22202456

Family Applications (1)

Application Number Title Priority Date Filing Date
PH37189A PH30953A (en) 1987-07-09 1988-07-07 Azithromycin dihydrate.

Country Status (45)

Country Link
US (1) US6268489B1 (fi)
EP (1) EP0298650B1 (fi)
JP (1) JPH0631300B2 (fi)
KR (1) KR900006218B1 (fi)
CN (1) CN1016785B (fi)
AP (1) AP44A (fi)
AR (1) AR243532A1 (fi)
AT (1) ATE72446T1 (fi)
AU (1) AU604553B2 (fi)
BA (1) BA98213B1 (fi)
BG (1) BG47348A3 (fi)
CA (1) CA1314876C (fi)
CS (1) CS272241B2 (fi)
CY (1) CY1776A (fi)
DD (1) DD271705A5 (fi)
DE (1) DE3868296D1 (fi)
DK (1) DK172573B1 (fi)
EG (1) EG18527A (fi)
ES (1) ES2038756T3 (fi)
FI (1) FI91263C (fi)
GR (1) GR3003737T3 (fi)
HK (1) HK127594A (fi)
HU (1) HU211862A9 (fi)
IE (1) IE60354B1 (fi)
IL (1) IL86979A (fi)
IN (1) IN168879B (fi)
IS (1) IS1540B (fi)
LV (1) LV10624B (fi)
MA (1) MA21323A1 (fi)
MX (1) MX12213A (fi)
MY (1) MY103744A (fi)
NO (1) NO171556C (fi)
NZ (1) NZ225338A (fi)
OA (1) OA08743A (fi)
PH (1) PH30953A (fi)
PL (1) PL157145B1 (fi)
PT (1) PT87933B (fi)
RO (1) RO107257B1 (fi)
RU (1) RU2066324C1 (fi)
SG (1) SG27794G (fi)
SI (1) SI8811325A8 (fi)
UA (1) UA27040C2 (fi)
WO (1) WO1989000576A1 (fi)
YU (1) YU45075B (fi)
ZA (1) ZA884925B (fi)

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US5912331A (en) * 1991-03-15 1999-06-15 Merck & Co., Inc. Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
US5985844A (en) * 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers
CA2081268A1 (en) * 1991-10-25 1993-04-26 Katsuhiro Imaki Glycine derivative monosodium salt tetrahydrate
US5215980A (en) * 1992-01-17 1993-06-01 Merck & Co., Inc. 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives thereof
US5210235A (en) * 1992-08-26 1993-05-11 Merck & Co., Inc. Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
CN1034734C (zh) * 1993-12-10 1997-04-30 北京市集才药物研究所 一种新的阿齐红霉素结晶及其制备方法
US5605889A (en) 1994-04-29 1997-02-25 Pfizer Inc. Method of administering azithromycin
CN1096862C (zh) 1994-05-06 2002-12-25 辉瑞大药厂 阿齐霉素的控释剂型
ES2122905B1 (es) * 1996-07-11 1999-11-16 Astur Pharma Sa Sintesis de 11,12-hidrogenoortoborato de 9-desoxo-9a-aza-11,12-desoxi-9a-metil-9a-homoeritromicina a. un procedimiento para la preparacion de 9-desoxo-9a-aza-9a-metil-9a-homoeritromicina a dihidrato (azitromicina dihidrato).
DE69824201T2 (de) * 1997-10-16 2005-09-22 Pliva - Istrazivacki Institut D.O.O. Neue 9a-azalide
US6861411B1 (en) 1997-12-02 2005-03-01 Pfizer, Inc. Method of treating eye infections with azithromycin
PT102130A (pt) * 1998-03-13 1999-09-30 Hovione Sociedade Quimica S A Processo de preparacao de dihidrato de azitromicina
TW546302B (en) * 1998-05-08 2003-08-11 Biochemie Sa Improvements in macrolide production
CA2245398C (en) 1998-08-21 2002-01-29 Apotex Inc. Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof
JP2002531409A (ja) 1998-11-30 2002-09-24 テバ ファーマシューティカル インダストリーズ リミティド アジスロマイシンのエタノール付加物、その製造方法、及びその医薬製剤
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CN1203084C (zh) * 1999-05-18 2005-05-25 辉瑞产品公司 大环内酯抗生素的新晶形
DE60029589T2 (de) * 1999-06-29 2007-07-19 Sandoz Ag Verfahren zur herstellung von azithromycin
ES2177373B1 (es) * 1999-11-26 2003-11-01 Astur Pharma Sa Preparacion de azitromicina en su forma no cristalina
CA2396426A1 (en) * 2000-01-04 2001-07-12 Teva Pharmaceutical Industries Ltd. Preparation method of azithromycin dihydrate
ES2162764B1 (es) * 2000-05-17 2003-04-01 Ercros Ind Sa Forma polimorfica del dihidrato de azitromicina, y su procedimiento deobtencion.
AU2000270425A1 (en) 2000-07-25 2002-02-13 Instituto De Investigacion En Quimica Aplicada S.C Single-step process for preparing 7,16-deoxy-2-aza-10-o-cladinosil-12-o-desosaminil-4,5-dihydr oxi-6-ethyl-3,5,9,11,13,15-hexamethylbicycle (11.2.1)hexadeca-1(2)-en-8-ona and obtaining a new form of 9-desoxo-9a-methyl-9a-aza-9a-homoerythromycin
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CN101624412B (zh) * 2008-07-10 2012-07-04 刘力 大环内酯类衍生物及其制备和用途
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CN103159811A (zh) * 2011-12-10 2013-06-19 山东方明药业集团股份有限公司 一种阿齐霉素中间体9a-脱氧-9a-氮杂-9a-高红霉素A的制备方法
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Also Published As

Publication number Publication date
FI900087A (fi) 1990-01-08
DK380688A (da) 1989-01-10
MA21323A1 (fr) 1989-04-01
SG27794G (en) 1994-10-14
NO900077D0 (no) 1990-01-08
EP0298650B1 (en) 1992-02-05
CS489688A2 (en) 1990-03-14
JPS6438096A (en) 1989-02-08
EG18527A (en) 1993-10-30
PL157145B1 (en) 1992-04-30
OA08743A (fr) 1989-03-31
FI91263B (fi) 1994-02-28
WO1989000576A1 (en) 1989-01-26
YU132588A (en) 1990-02-28
CS272241B2 (en) 1991-01-15
SI8811325A8 (en) 1996-12-31
KR890002137A (ko) 1989-04-08
BA98213B1 (bs) 1999-08-02
EP0298650A2 (en) 1989-01-11
AP44A (en) 1989-07-27
RO107257B1 (ro) 1993-10-30
NO171556C (no) 1993-03-31
MX12213A (es) 1993-05-01
CA1314876C (en) 1993-03-23
HK127594A (en) 1994-11-25
KR900006218B1 (ko) 1990-08-25
HU211862A9 (en) 1995-12-28
LV10624A (lv) 1995-04-20
US6268489B1 (en) 2001-07-31
AR243532A1 (es) 1993-08-31
DK380688D0 (da) 1988-07-08
FI900087A0 (fi) 1990-01-08
AP8800093A0 (en) 1988-05-01
AU604553B2 (en) 1990-12-20
IE60354B1 (en) 1994-06-29
JPH0631300B2 (ja) 1994-04-27
PL273590A1 (en) 1989-03-20
GR3003737T3 (fi) 1993-03-16
IN168879B (fi) 1991-06-29
BG47348A3 (en) 1990-06-15
ES2038756T3 (es) 1993-08-01
ZA884925B (en) 1990-02-28
DD271705A5 (de) 1989-09-13
CN1030422A (zh) 1989-01-18
RU2066324C1 (ru) 1996-09-10
NO900077L (no) 1990-01-08
ATE72446T1 (de) 1992-02-15
CY1776A (en) 1995-10-20
IS1540B (is) 1994-01-28
EP0298650A3 (en) 1989-11-08
NZ225338A (en) 1990-02-26
PT87933A (pt) 1989-06-30
UA27040C2 (uk) 2000-02-28
LV10624B (en) 1995-10-20
FI91263C (fi) 1994-06-10
DK172573B1 (da) 1999-01-25
IS3370A7 (is) 1989-01-10
MY103744A (en) 1993-09-30
PT87933B (pt) 1994-09-30
CN1016785B (zh) 1992-05-27
IE882108L (en) 1989-01-09
NO171556B (no) 1992-12-21
YU45075B (en) 1991-08-31
AU1883988A (en) 1989-01-12
IL86979A0 (en) 1988-12-30
DE3868296D1 (de) 1992-03-19
IL86979A (en) 1992-11-15

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