NO900077L - Fremgangsmaate for fremstilling av azitromycin-dihydrat. - Google Patents

Fremgangsmaate for fremstilling av azitromycin-dihydrat.

Info

Publication number
NO900077L
NO900077L NO90900077A NO900077A NO900077L NO 900077 L NO900077 L NO 900077L NO 90900077 A NO90900077 A NO 90900077A NO 900077 A NO900077 A NO 900077A NO 900077 L NO900077 L NO 900077L
Authority
NO
Norway
Prior art keywords
azitromycin
dihydrate
procedure
preparation
azitromycin dihydrate
Prior art date
Application number
NO90900077A
Other languages
English (en)
Other versions
NO171556B (no
NO171556C (no
NO900077D0 (no
Inventor
Douglas John Meldrum Allen
Kevin Michael Nepveux
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22202456&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO900077(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of NO900077L publication Critical patent/NO900077L/no
Publication of NO900077D0 publication Critical patent/NO900077D0/no
Publication of NO171556B publication Critical patent/NO171556B/no
Publication of NO171556C publication Critical patent/NO171556C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
NO90900077A 1987-07-09 1990-01-08 Fremgangsmaate for fremstilling av azitromycin dihydrat NO171556C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/001612 WO1989000576A1 (en) 1987-07-09 1987-07-09 Azithromycin dihydrate

Publications (4)

Publication Number Publication Date
NO900077L true NO900077L (no) 1990-01-08
NO900077D0 NO900077D0 (no) 1990-01-08
NO171556B NO171556B (no) 1992-12-21
NO171556C NO171556C (no) 1993-03-31

Family

ID=22202456

Family Applications (1)

Application Number Title Priority Date Filing Date
NO90900077A NO171556C (no) 1987-07-09 1990-01-08 Fremgangsmaate for fremstilling av azitromycin dihydrat

Country Status (45)

Country Link
US (1) US6268489B1 (no)
EP (1) EP0298650B1 (no)
JP (1) JPH0631300B2 (no)
KR (1) KR900006218B1 (no)
CN (1) CN1016785B (no)
AP (1) AP44A (no)
AR (1) AR243532A1 (no)
AT (1) ATE72446T1 (no)
AU (1) AU604553B2 (no)
BA (1) BA98213B1 (no)
BG (1) BG47348A3 (no)
CA (1) CA1314876C (no)
CS (1) CS272241B2 (no)
CY (1) CY1776A (no)
DD (1) DD271705A5 (no)
DE (1) DE3868296D1 (no)
DK (1) DK172573B1 (no)
EG (1) EG18527A (no)
ES (1) ES2038756T3 (no)
FI (1) FI91263C (no)
GR (1) GR3003737T3 (no)
HK (1) HK127594A (no)
HU (1) HU211862A9 (no)
IE (1) IE60354B1 (no)
IL (1) IL86979A (no)
IN (1) IN168879B (no)
IS (1) IS1540B (no)
LV (1) LV10624B (no)
MA (1) MA21323A1 (no)
MX (1) MX12213A (no)
MY (1) MY103744A (no)
NO (1) NO171556C (no)
NZ (1) NZ225338A (no)
OA (1) OA08743A (no)
PH (1) PH30953A (no)
PL (1) PL157145B1 (no)
PT (1) PT87933B (no)
RO (1) RO107257B1 (no)
RU (1) RU2066324C1 (no)
SG (1) SG27794G (no)
SI (1) SI8811325A8 (no)
UA (1) UA27040C2 (no)
WO (1) WO1989000576A1 (no)
YU (1) YU45075B (no)
ZA (1) ZA884925B (no)

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US5912331A (en) * 1991-03-15 1999-06-15 Merck & Co., Inc. Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
US5985844A (en) * 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers
CA2081268A1 (en) * 1991-10-25 1993-04-26 Katsuhiro Imaki Glycine derivative monosodium salt tetrahydrate
US5215980A (en) * 1992-01-17 1993-06-01 Merck & Co., Inc. 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives thereof
US5210235A (en) * 1992-08-26 1993-05-11 Merck & Co., Inc. Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
CN1034734C (zh) * 1993-12-10 1997-04-30 北京市集才药物研究所 一种新的阿齐红霉素结晶及其制备方法
US5605889A (en) 1994-04-29 1997-02-25 Pfizer Inc. Method of administering azithromycin
SI9520049A (en) 1994-05-06 1997-12-31 Pfizer Controlled-release dosage forms of azithromycin
ES2122905B1 (es) * 1996-07-11 1999-11-16 Astur Pharma Sa Sintesis de 11,12-hidrogenoortoborato de 9-desoxo-9a-aza-11,12-desoxi-9a-metil-9a-homoeritromicina a. un procedimiento para la preparacion de 9-desoxo-9a-aza-9a-metil-9a-homoeritromicina a dihidrato (azitromicina dihidrato).
EP1437359B1 (en) * 1997-10-16 2006-12-20 GlaxoSmithKline istrazivacki centar Zagreb d.o.o. Novel 3,6-Hemiketals from the Class of 9a-Azalides
US6861411B1 (en) 1997-12-02 2005-03-01 Pfizer, Inc. Method of treating eye infections with azithromycin
PT102130A (pt) * 1998-03-13 1999-09-30 Hovione Sociedade Quimica S A Processo de preparacao de dihidrato de azitromicina
TW546302B (en) 1998-05-08 2003-08-11 Biochemie Sa Improvements in macrolide production
CA2245398C (en) * 1998-08-21 2002-01-29 Apotex Inc. Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof
AU768219B2 (en) 1998-11-30 2003-12-04 Teva Pharmaceutical Industries Ltd. Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof
US7056893B2 (en) 1999-03-31 2006-06-06 Insite Vision, Inc. Topical treatment for prevention of ocular infections
US6239113B1 (en) 1999-03-31 2001-05-29 Insite Vision, Incorporated Topical treatment or prevention of ocular infections
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DE60029589T2 (de) * 1999-06-29 2007-07-19 Sandoz Ag Verfahren zur herstellung von azithromycin
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WO2002010144A1 (es) 2000-07-25 2002-02-07 Laboratorio Silanes, S.A. De C.V. PROCESO PARA LA PREPARACION EN UN SOLO PASO DE 7,16-DIOXA-2-AZA-10-O-CLADINOSIL-12-O-DESOSAMINIL-4,5-DIHIDROXI-6-ETIL-3,5,9,11,13,15-HEXAMETILBICICLO[11.2.1]HEXADECA-1(2)-EN-8-ONA Y OBTENCION DE UNA FORMA NUEVA DE 9-DESOXO-9a-AZA-9a-METIL-9a-HOMOERITROMICINA A
ES2172417B1 (es) * 2000-07-31 2003-09-16 Sint Quimica Sa Nueva forma mejorada de azitromicina monohidrato de menor higroscopicidad, procedimiento de preparacion y composiciones farmaceuticas que la comprenden.
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Also Published As

Publication number Publication date
LV10624A (lv) 1995-04-20
IS3370A7 (is) 1989-01-10
IN168879B (no) 1991-06-29
EP0298650B1 (en) 1992-02-05
CS489688A2 (en) 1990-03-14
YU132588A (en) 1990-02-28
IL86979A0 (en) 1988-12-30
NO171556B (no) 1992-12-21
WO1989000576A1 (en) 1989-01-26
OA08743A (fr) 1989-03-31
NO171556C (no) 1993-03-31
CN1016785B (zh) 1992-05-27
DD271705A5 (de) 1989-09-13
PT87933A (pt) 1989-06-30
HU211862A9 (en) 1995-12-28
RU2066324C1 (ru) 1996-09-10
ZA884925B (en) 1990-02-28
DK172573B1 (da) 1999-01-25
MA21323A1 (fr) 1989-04-01
RO107257B1 (ro) 1993-10-30
EG18527A (en) 1993-10-30
CA1314876C (en) 1993-03-23
AP8800093A0 (en) 1988-05-01
AU604553B2 (en) 1990-12-20
AU1883988A (en) 1989-01-12
PL273590A1 (en) 1989-03-20
CY1776A (en) 1995-10-20
US6268489B1 (en) 2001-07-31
CS272241B2 (en) 1991-01-15
ATE72446T1 (de) 1992-02-15
BG47348A3 (en) 1990-06-15
PT87933B (pt) 1994-09-30
AP44A (en) 1989-07-27
ES2038756T3 (es) 1993-08-01
DK380688D0 (da) 1988-07-08
LV10624B (en) 1995-10-20
DK380688A (da) 1989-01-10
BA98213B1 (bs) 1999-08-02
UA27040C2 (uk) 2000-02-28
IL86979A (en) 1992-11-15
AR243532A1 (es) 1993-08-31
FI91263C (fi) 1994-06-10
SG27794G (en) 1994-10-14
DE3868296D1 (de) 1992-03-19
IE60354B1 (en) 1994-06-29
CN1030422A (zh) 1989-01-18
KR890002137A (ko) 1989-04-08
HK127594A (en) 1994-11-25
FI900087A (fi) 1990-01-08
MY103744A (en) 1993-09-30
IS1540B (is) 1994-01-28
JPS6438096A (en) 1989-02-08
EP0298650A2 (en) 1989-01-11
NO900077D0 (no) 1990-01-08
SI8811325A8 (en) 1996-12-31
FI91263B (fi) 1994-02-28
IE882108L (en) 1989-01-09
PL157145B1 (en) 1992-04-30
NZ225338A (en) 1990-02-26
FI900087A0 (fi) 1990-01-08
JPH0631300B2 (ja) 1994-04-27
EP0298650A3 (en) 1989-11-08
MX12213A (es) 1993-05-01
KR900006218B1 (ko) 1990-08-25
GR3003737T3 (no) 1993-03-16
YU45075B (en) 1991-08-31
PH30953A (en) 1997-12-23

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