UA27040C2 - Кристалічhий дигідрат азитроміциhу та спосіб одержаhhя кристалічhого дигідрату азитроміциhу - Google Patents

Кристалічhий дигідрат азитроміциhу та спосіб одержаhhя кристалічhого дигідрату азитроміциhу

Info

Publication number
UA27040C2
UA27040C2 UA93004522A UA93004522A UA27040C2 UA 27040 C2 UA27040 C2 UA 27040C2 UA 93004522 A UA93004522 A UA 93004522A UA 93004522 A UA93004522 A UA 93004522A UA 27040 C2 UA27040 C2 UA 27040C2
Authority
UA
Ukraine
Prior art keywords
obtaining
crystalline azithromycin
azithromycin dehydrate
crystalline
directed
Prior art date
Application number
UA93004522A
Other languages
English (en)
Russian (ru)
Inventor
Дуглас Дж. М. АЛЛЕН
Кевін М. Нев'ю
Кевин М Невью
Original Assignee
Пфайзер Інк.
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22202456&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA27040(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Пфайзер Інк., Пфайзер Инк. filed Critical Пфайзер Інк.
Publication of UA27040C2 publication Critical patent/UA27040C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Винахід стосується кристалічного дигідрату азитроміцину формули , що має антибактеріальну активність. Винахід стосується нової цінної форми азитроміцину (9-деоксо-9а-аза-9а-метил-9а-гомоеритроміцин А), а саме негігроскопічної де гідратної форми цієї сполуки.
UA93004522A 1987-07-09 1987-07-09 Кристалічhий дигідрат азитроміциhу та спосіб одержаhhя кристалічhого дигідрату азитроміциhу UA27040C2 (uk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/001612 WO1989000576A1 (en) 1987-07-09 1987-07-09 Azithromycin dihydrate

Publications (1)

Publication Number Publication Date
UA27040C2 true UA27040C2 (uk) 2000-02-28

Family

ID=22202456

Family Applications (1)

Application Number Title Priority Date Filing Date
UA93004522A UA27040C2 (uk) 1987-07-09 1987-07-09 Кристалічhий дигідрат азитроміциhу та спосіб одержаhhя кристалічhого дигідрату азитроміциhу

Country Status (45)

Country Link
US (1) US6268489B1 (uk)
EP (1) EP0298650B1 (uk)
JP (1) JPH0631300B2 (uk)
KR (1) KR900006218B1 (uk)
CN (1) CN1016785B (uk)
AP (1) AP44A (uk)
AR (1) AR243532A1 (uk)
AT (1) ATE72446T1 (uk)
AU (1) AU604553B2 (uk)
BA (1) BA98213B1 (uk)
BG (1) BG47348A3 (uk)
CA (1) CA1314876C (uk)
CS (1) CS272241B2 (uk)
CY (1) CY1776A (uk)
DD (1) DD271705A5 (uk)
DE (1) DE3868296D1 (uk)
DK (1) DK172573B1 (uk)
EG (1) EG18527A (uk)
ES (1) ES2038756T3 (uk)
FI (1) FI91263C (uk)
GR (1) GR3003737T3 (uk)
HK (1) HK127594A (uk)
HU (1) HU211862A9 (uk)
IE (1) IE60354B1 (uk)
IL (1) IL86979A (uk)
IN (1) IN168879B (uk)
IS (1) IS1540B (uk)
LV (1) LV10624B (uk)
MA (1) MA21323A1 (uk)
MX (1) MX12213A (uk)
MY (1) MY103744A (uk)
NO (1) NO171556C (uk)
NZ (1) NZ225338A (uk)
OA (1) OA08743A (uk)
PH (1) PH30953A (uk)
PL (1) PL157145B1 (uk)
PT (1) PT87933B (uk)
RO (1) RO107257B1 (uk)
RU (1) RU2066324C1 (uk)
SG (1) SG27794G (uk)
SI (1) SI8811325A8 (uk)
UA (1) UA27040C2 (uk)
WO (1) WO1989000576A1 (uk)
YU (1) YU45075B (uk)
ZA (1) ZA884925B (uk)

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WO1989002271A1 (en) 1987-09-10 1989-03-23 Pfizer Azithromycin and derivatives as antiprotozoal agents

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OA08743A (fr) 1989-03-31
DE3868296D1 (de) 1992-03-19
PL273590A1 (en) 1989-03-20
DK380688D0 (da) 1988-07-08
ES2038756T3 (es) 1993-08-01
PT87933B (pt) 1994-09-30
FI91263B (fi) 1994-02-28
KR900006218B1 (ko) 1990-08-25
AP8800093A0 (en) 1988-05-01
AU604553B2 (en) 1990-12-20
MA21323A1 (fr) 1989-04-01
RO107257B1 (ro) 1993-10-30
GR3003737T3 (uk) 1993-03-16
WO1989000576A1 (en) 1989-01-26
JPH0631300B2 (ja) 1994-04-27
AU1883988A (en) 1989-01-12
BG47348A3 (en) 1990-06-15
AR243532A1 (es) 1993-08-31
LV10624A (lv) 1995-04-20
NO171556C (no) 1993-03-31
IL86979A0 (en) 1988-12-30
JPS6438096A (en) 1989-02-08
PH30953A (en) 1997-12-23
EP0298650B1 (en) 1992-02-05
NO900077L (no) 1990-01-08
ATE72446T1 (de) 1992-02-15
IS3370A7 (is) 1989-01-10
EG18527A (en) 1993-10-30
CN1030422A (zh) 1989-01-18
DK380688A (da) 1989-01-10
NO900077D0 (no) 1990-01-08
BA98213B1 (bs) 1999-08-02
AP44A (en) 1989-07-27
US6268489B1 (en) 2001-07-31
HU211862A9 (en) 1995-12-28
HK127594A (en) 1994-11-25
NZ225338A (en) 1990-02-26
CA1314876C (en) 1993-03-23
ZA884925B (en) 1990-02-28
MY103744A (en) 1993-09-30
MX12213A (es) 1993-05-01
CN1016785B (zh) 1992-05-27
IS1540B (is) 1994-01-28
NO171556B (no) 1992-12-21
YU132588A (en) 1990-02-28
CS272241B2 (en) 1991-01-15
DD271705A5 (de) 1989-09-13
IE60354B1 (en) 1994-06-29
SI8811325A8 (en) 1996-12-31
IE882108L (en) 1989-01-09
EP0298650A2 (en) 1989-01-11
PL157145B1 (en) 1992-04-30
FI900087A (fi) 1990-01-08
SG27794G (en) 1994-10-14
IN168879B (uk) 1991-06-29
LV10624B (en) 1995-10-20
FI91263C (fi) 1994-06-10
IL86979A (en) 1992-11-15
CS489688A2 (en) 1990-03-14
EP0298650A3 (en) 1989-11-08
RU2066324C1 (ru) 1996-09-10
CY1776A (en) 1995-10-20
KR890002137A (ko) 1989-04-08
FI900087A0 (fi) 1990-01-08
YU45075B (en) 1991-08-31
DK172573B1 (da) 1999-01-25
PT87933A (pt) 1989-06-30

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