ZA855594B - Naphthyl analogs of mevalonolactone and derivatives thereof,processes for their production and their use - Google Patents
Naphthyl analogs of mevalonolactone and derivatives thereof,processes for their production and their useInfo
- Publication number
- ZA855594B ZA855594B ZA855594A ZA855594A ZA855594B ZA 855594 B ZA855594 B ZA 855594B ZA 855594 A ZA855594 A ZA 855594A ZA 855594 A ZA855594 A ZA 855594A ZA 855594 B ZA855594 B ZA 855594B
- Authority
- ZA
- South Africa
- Prior art keywords
- mevalonolactone
- derivatives
- processes
- production
- naphthyl analogs
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C07C57/38—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
- C07C57/40—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic containing condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyrane Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63380984A | 1984-07-24 | 1984-07-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA855594B true ZA855594B (en) | 1987-02-25 |
Family
ID=24541204
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA855594A ZA855594B (en) | 1984-07-24 | 1985-07-24 | Naphthyl analogs of mevalonolactone and derivatives thereof,processes for their production and their use |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS6137754A (en) |
| KR (1) | KR860001045A (en) |
| AU (1) | AU4522685A (en) |
| BE (1) | BE902914A (en) |
| DE (1) | DE3525256A1 (en) |
| DK (1) | DK333785A (en) |
| ES (1) | ES8705356A1 (en) |
| FI (1) | FI852851L (en) |
| FR (1) | FR2568248A1 (en) |
| GB (1) | GB2162179A (en) |
| GR (1) | GR851805B (en) |
| HU (1) | HUT39142A (en) |
| IL (1) | IL75874A0 (en) |
| IT (1) | IT1200095B (en) |
| LU (1) | LU86012A1 (en) |
| NL (1) | NL8502010A (en) |
| PH (1) | PH21444A (en) |
| PL (1) | PL254654A1 (en) |
| PT (1) | PT80845B (en) |
| SE (1) | SE8503556L (en) |
| ZA (1) | ZA855594B (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5091378A (en) * | 1987-05-22 | 1992-02-25 | E. R. Squibb & Sons, Inc. | Phosphorus-containing HMG-CoA reductase inhibitors, new intermediates and method |
| US4904646A (en) * | 1987-05-22 | 1990-02-27 | E. R. Squibb & Sons, Inc. | Phosphorus-containing HMG-COA reductase inhibitors |
| DE3722807A1 (en) * | 1987-07-10 | 1989-01-19 | Hoechst Ag | NEW 3,5-DIHYDROXYCARBONIC ACIDS AND THEIR DERIVATIVES, PROCESS FOR THEIR PRODUCTION, THEIR USE AS MEDICINAL PRODUCTS, PHARMACEUTICAL PREPARATIONS AND INTERMEDIATE PRODUCTS |
| US4792614A (en) * | 1987-08-05 | 1988-12-20 | American Home Products Corporation | Substituted furans as inhibitors of 3-hydroxy-3-methylglutaryl-coa reductase |
| US4812583A (en) * | 1987-09-11 | 1989-03-14 | American Home Products Corporation | Substituted acyloxyalkylphenylethylene inhibitors of 3-hydroxy-3-methylglutaryl-coa reductase |
| DE3818570A1 (en) * | 1988-06-01 | 1989-12-21 | Boehringer Mannheim Gmbh | NEW 6-SUBSTITUTED-4-HYDROXY-TETRAHYDRO-PYRANE-2-ON-DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS |
| US5506219A (en) * | 1988-08-29 | 1996-04-09 | E. R. Squibb & Sons, Inc. | Pyridine anchors for HMG-CoA reductase inhibitors |
| CA2185961A1 (en) * | 1996-09-19 | 1998-03-20 | K.S. Keshava Murthy | Process for producing simvastatin |
| US20010006644A1 (en) | 1997-07-31 | 2001-07-05 | David J. Bova | Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night |
| KR100836960B1 (en) | 2007-09-07 | 2008-06-10 | 주식회사 서울제약 | A novel controlled release-niacin formulation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55132595A (en) * | 1979-04-04 | 1980-10-15 | Nec Corp | Semiconductor circuit |
-
1985
- 1985-07-12 HU HU852696A patent/HUT39142A/en unknown
- 1985-07-12 NL NL8502010A patent/NL8502010A/en not_active Application Discontinuation
- 1985-07-15 DE DE19853525256 patent/DE3525256A1/en not_active Withdrawn
- 1985-07-16 FR FR8510988A patent/FR2568248A1/en active Pending
- 1985-07-17 BE BE1/011302A patent/BE902914A/en not_active IP Right Cessation
- 1985-07-22 KR KR1019850005206A patent/KR860001045A/en not_active Application Discontinuation
- 1985-07-22 SE SE8503556A patent/SE8503556L/en not_active Application Discontinuation
- 1985-07-22 PT PT80845A patent/PT80845B/en unknown
- 1985-07-22 GB GB08518490A patent/GB2162179A/en not_active Withdrawn
- 1985-07-22 FI FI852851A patent/FI852851L/en not_active Application Discontinuation
- 1985-07-22 ES ES545454A patent/ES8705356A1/en not_active Expired
- 1985-07-22 AU AU45226/85A patent/AU4522685A/en not_active Abandoned
- 1985-07-22 PH PH32550A patent/PH21444A/en unknown
- 1985-07-22 DK DK333785A patent/DK333785A/en not_active Application Discontinuation
- 1985-07-22 IL IL75874A patent/IL75874A0/en unknown
- 1985-07-22 LU LU86012A patent/LU86012A1/en unknown
- 1985-07-22 GR GR851805A patent/GR851805B/el unknown
- 1985-07-23 IT IT8548385A patent/IT1200095B/en active
- 1985-07-23 JP JP16278685A patent/JPS6137754A/en active Pending
- 1985-07-23 PL PL25465485A patent/PL254654A1/en unknown
- 1985-07-24 ZA ZA855594A patent/ZA855594B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT80845A (en) | 1985-08-01 |
| JPS6137754A (en) | 1986-02-22 |
| IT1200095B (en) | 1989-01-05 |
| AU4522685A (en) | 1986-01-30 |
| BE902914A (en) | 1986-01-17 |
| SE8503556L (en) | 1986-01-25 |
| ES545454A0 (en) | 1987-05-01 |
| DE3525256A1 (en) | 1986-01-30 |
| SE8503556D0 (en) | 1985-07-22 |
| FI852851L (en) | 1986-01-25 |
| ES8705356A1 (en) | 1987-05-01 |
| IL75874A0 (en) | 1985-11-29 |
| GB2162179A (en) | 1986-01-29 |
| GR851805B (en) | 1985-11-26 |
| FI852851A0 (en) | 1985-07-22 |
| FR2568248A1 (en) | 1986-01-31 |
| PT80845B (en) | 1987-03-24 |
| PL254654A1 (en) | 1986-08-26 |
| PH21444A (en) | 1987-10-20 |
| LU86012A1 (en) | 1986-02-12 |
| GB8518490D0 (en) | 1985-08-29 |
| NL8502010A (en) | 1986-02-17 |
| IT8548385A0 (en) | 1985-07-23 |
| DK333785D0 (en) | 1985-07-22 |
| HUT39142A (en) | 1986-08-28 |
| KR860001045A (en) | 1986-02-22 |
| DK333785A (en) | 1986-01-25 |
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