ES545454A0 - PROCEDURE FOR THE PREPARATION OF NAVYL-ANALOGUE COMPOUNDS OF MEVALONOLACTONE AND ITS DERIVATIVES - Google Patents

PROCEDURE FOR THE PREPARATION OF NAVYL-ANALOGUE COMPOUNDS OF MEVALONOLACTONE AND ITS DERIVATIVES

Info

Publication number
ES545454A0
ES545454A0 ES545454A ES545454A ES545454A0 ES 545454 A0 ES545454 A0 ES 545454A0 ES 545454 A ES545454 A ES 545454A ES 545454 A ES545454 A ES 545454A ES 545454 A0 ES545454 A0 ES 545454A0
Authority
ES
Spain
Prior art keywords
navyl
mevalonolactone
derivatives
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES545454A
Other languages
Spanish (es)
Other versions
ES8705356A1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES545454A0 publication Critical patent/ES545454A0/en
Publication of ES8705356A1 publication Critical patent/ES8705356A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • C07C57/40Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic containing condensed ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30Oxygen atoms, e.g. delta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ES545454A 1984-07-24 1985-07-22 Naphthyl analogs of mevalonolactone and derivatives thereof, processes for their production and their use Expired ES8705356A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63380984A 1984-07-24 1984-07-24

Publications (2)

Publication Number Publication Date
ES545454A0 true ES545454A0 (en) 1987-05-01
ES8705356A1 ES8705356A1 (en) 1987-05-01

Family

ID=24541204

Family Applications (1)

Application Number Title Priority Date Filing Date
ES545454A Expired ES8705356A1 (en) 1984-07-24 1985-07-22 Naphthyl analogs of mevalonolactone and derivatives thereof, processes for their production and their use

Country Status (21)

Country Link
JP (1) JPS6137754A (en)
KR (1) KR860001045A (en)
AU (1) AU4522685A (en)
BE (1) BE902914A (en)
DE (1) DE3525256A1 (en)
DK (1) DK333785A (en)
ES (1) ES8705356A1 (en)
FI (1) FI852851L (en)
FR (1) FR2568248A1 (en)
GB (1) GB2162179A (en)
GR (1) GR851805B (en)
HU (1) HUT39142A (en)
IL (1) IL75874A0 (en)
IT (1) IT1200095B (en)
LU (1) LU86012A1 (en)
NL (1) NL8502010A (en)
PH (1) PH21444A (en)
PL (1) PL254654A1 (en)
PT (1) PT80845B (en)
SE (1) SE8503556L (en)
ZA (1) ZA855594B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5091378A (en) * 1987-05-22 1992-02-25 E. R. Squibb & Sons, Inc. Phosphorus-containing HMG-CoA reductase inhibitors, new intermediates and method
US4904646A (en) * 1987-05-22 1990-02-27 E. R. Squibb & Sons, Inc. Phosphorus-containing HMG-COA reductase inhibitors
DE3722807A1 (en) * 1987-07-10 1989-01-19 Hoechst Ag NEW 3,5-DIHYDROXYCARBONIC ACIDS AND THEIR DERIVATIVES, PROCESS FOR THEIR PRODUCTION, THEIR USE AS MEDICINAL PRODUCTS, PHARMACEUTICAL PREPARATIONS AND INTERMEDIATE PRODUCTS
US4792614A (en) * 1987-08-05 1988-12-20 American Home Products Corporation Substituted furans as inhibitors of 3-hydroxy-3-methylglutaryl-coa reductase
US4812583A (en) * 1987-09-11 1989-03-14 American Home Products Corporation Substituted acyloxyalkylphenylethylene inhibitors of 3-hydroxy-3-methylglutaryl-coa reductase
DE3818570A1 (en) * 1988-06-01 1989-12-21 Boehringer Mannheim Gmbh NEW 6-SUBSTITUTED-4-HYDROXY-TETRAHYDRO-PYRANE-2-ON-DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS
US5506219A (en) * 1988-08-29 1996-04-09 E. R. Squibb & Sons, Inc. Pyridine anchors for HMG-CoA reductase inhibitors
CA2185961A1 (en) * 1996-09-19 1998-03-20 K.S. Keshava Murthy Process for producing simvastatin
US20010006644A1 (en) 1997-07-31 2001-07-05 David J. Bova Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night
KR100836960B1 (en) 2007-09-07 2008-06-10 주식회사 서울제약 A novel controlled release-niacin formulation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55132595A (en) * 1979-04-04 1980-10-15 Nec Corp Semiconductor circuit

Also Published As

Publication number Publication date
KR860001045A (en) 1986-02-22
PT80845A (en) 1985-08-01
JPS6137754A (en) 1986-02-22
PH21444A (en) 1987-10-20
IT1200095B (en) 1989-01-05
GB2162179A (en) 1986-01-29
SE8503556D0 (en) 1985-07-22
GB8518490D0 (en) 1985-08-29
IT8548385A0 (en) 1985-07-23
DK333785D0 (en) 1985-07-22
NL8502010A (en) 1986-02-17
DK333785A (en) 1986-01-25
LU86012A1 (en) 1986-02-12
AU4522685A (en) 1986-01-30
IL75874A0 (en) 1985-11-29
PL254654A1 (en) 1986-08-26
ES8705356A1 (en) 1987-05-01
FI852851L (en) 1986-01-25
ZA855594B (en) 1987-02-25
HUT39142A (en) 1986-08-28
DE3525256A1 (en) 1986-01-30
FI852851A0 (en) 1985-07-22
GR851805B (en) 1985-11-26
FR2568248A1 (en) 1986-01-31
SE8503556L (en) 1986-01-25
PT80845B (en) 1987-03-24
BE902914A (en) 1986-01-17

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