NZ744885A - Method for preparing pyrrolo[3,2-d]pyrimidine compound, and intermediates thereof - Google Patents

Method for preparing pyrrolo[3,2-d]pyrimidine compound, and intermediates thereof

Info

Publication number
NZ744885A
NZ744885A NZ744885A NZ74488517A NZ744885A NZ 744885 A NZ744885 A NZ 744885A NZ 744885 A NZ744885 A NZ 744885A NZ 74488517 A NZ74488517 A NZ 74488517A NZ 744885 A NZ744885 A NZ 744885A
Authority
NZ
New Zealand
Prior art keywords
compound
formula
acid
group
sodium
Prior art date
Application number
NZ744885A
Other languages
English (en)
Inventor
Zhaozhong Ding
Ling Yang
Fei Sun
Yinghu Hu
Yilong Zhou
Rui Zhao
Original Assignee
Chia Tai Tianqing Pharmaceutical Group Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chia Tai Tianqing Pharmaceutical Group Co Ltd filed Critical Chia Tai Tianqing Pharmaceutical Group Co Ltd
Publication of NZ744885A publication Critical patent/NZ744885A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
NZ744885A 2016-02-05 2017-02-04 Method for preparing pyrrolo[3,2-d]pyrimidine compound, and intermediates thereof NZ744885A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201610082028.3A CN107043378A (zh) 2016-02-05 2016-02-05 一种吡咯并[3,2-d]嘧啶类化合物的制备方法及其中间体
PCT/CN2017/072893 WO2017133686A1 (zh) 2016-02-05 2017-02-04 一种吡咯并[3,2-d]嘧啶类化合物的制备方法及其中间体

Publications (1)

Publication Number Publication Date
NZ744885A true NZ744885A (en) 2022-07-01

Family

ID=59500148

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ744885A NZ744885A (en) 2016-02-05 2017-02-04 Method for preparing pyrrolo[3,2-d]pyrimidine compound, and intermediates thereof

Country Status (28)

Country Link
US (2) US10654856B2 (enExample)
EP (1) EP3412673B1 (enExample)
JP (1) JP6877449B2 (enExample)
KR (1) KR102371500B1 (enExample)
CN (2) CN107043378A (enExample)
AR (1) AR107549A1 (enExample)
AU (1) AU2017214134B2 (enExample)
BR (1) BR112018015879B1 (enExample)
CA (1) CA3013520C (enExample)
CL (1) CL2018002094A1 (enExample)
DK (1) DK3412673T3 (enExample)
EA (1) EA034581B1 (enExample)
ES (1) ES2852323T3 (enExample)
HR (1) HRP20210103T1 (enExample)
HU (1) HUE053455T2 (enExample)
IL (1) IL260999B (enExample)
LT (1) LT3412673T (enExample)
MX (1) MX374298B (enExample)
MY (1) MY190551A (enExample)
NZ (1) NZ744885A (enExample)
PH (1) PH12018501642A1 (enExample)
PL (1) PL3412673T3 (enExample)
PT (1) PT3412673T (enExample)
SG (1) SG11201806685VA (enExample)
SI (1) SI3412673T1 (enExample)
TW (1) TW201728590A (enExample)
UA (1) UA124100C2 (enExample)
WO (1) WO2017133686A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201891620A1 (ru) 2016-02-05 2019-02-28 Денали Терапьютикс Инк. Ингибиторы взаимодействующей с рецептором протеинкиназы 1
CN107043380A (zh) * 2016-02-05 2017-08-15 正大天晴药业集团股份有限公司 一种tlr7激动剂的马来酸盐、其晶型c、晶型d、晶型e、制备方法和用途
MX2021009496A (es) 2019-02-08 2021-09-08 Progeneer Inc Complejo de colesterol-agonista del receptor 7 u 8 tipo larga distancia, y uso del mismo.
WO2021177679A1 (ko) 2020-03-02 2021-09-10 성균관대학교산학협력단 병원균 외벽 성분 기반 생병원체 모방 나노 입자 및 그 제조 방법
EP4194006A4 (en) 2020-08-04 2024-12-04 Progeneer Inc. mRNA VACCINE WITH AN ADJUVANT CAPABLE OF KINETIC CONTROL
JP2023536954A (ja) 2020-08-04 2023-08-30 プロジェニア インコーポレイテッド 活性化部位が一時的に不活性化したトール様受容体7または8作用薬と機能性薬物の結合体およびその用途
US20230355750A1 (en) 2020-08-04 2023-11-09 Progeneer Inc. Kinetically acting adjuvant ensemble
MX2024008648A (es) 2022-01-12 2024-09-23 Denali Therapeutics Inc Formas cristalinas de (s)-5-bencil-n-(5-metil-4-oxo-2,3,4,5-tetrah idropirido [3,2- b][1,4]oxacepin-3-il)-4h-1,2,4-triazol-3-carboxam ida.

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009082247A1 (en) 2007-12-21 2009-07-02 Industrial Research Limited Process for preparing immucillins having a methylene link
NZ593110A (en) 2008-12-09 2013-06-28 Gilead Sciences Inc pteridinone derivatives as MODULATORS OF TOLL-LIKE RECEPTORS
MX365114B (es) * 2012-10-10 2019-05-23 Janssen Sciences Ireland Uc Derivados pirrolo[3,2-d]pirimidinicos para el tratamiento de infecciones viricas y otras enfermedades.
RU2643371C2 (ru) * 2012-11-20 2018-02-01 ГЛАКСОСМИТКЛАЙН ЭлЭлСи Новые соединения
JP6228223B2 (ja) * 2012-11-20 2017-11-08 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニーGlaxoSmithKline LLC 新規化合物
PL3137470T3 (pl) * 2014-05-01 2021-10-11 Novartis Ag Związki i kompozycje jako agonisty receptora toll-like 7
PL3190113T3 (pl) * 2014-08-15 2021-10-25 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Związki pirolopirymidynowe stosowane jako agonista TLR7
CN105367576A (zh) 2014-08-15 2016-03-02 正大天晴药业集团股份有限公司 作为tlr7激动剂的吡咯并嘧啶化合物
BR112018008880B1 (pt) 2015-11-05 2023-01-17 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 7-(tiazol-5-il) pirrolopirimidina, seu uso, e composição farmacêutica
CN107043379A (zh) * 2016-02-05 2017-08-15 正大天晴药业集团股份有限公司 一种tlr7激动剂的晶型a、其制备方法和医药用途
CN107043377A (zh) * 2016-02-05 2017-08-15 正大天晴药业集团股份有限公司 一种tlr7激动剂的三氟乙酸盐、晶型b及其制备方法、药物组合物和用途
CN107043380A (zh) * 2016-02-05 2017-08-15 正大天晴药业集团股份有限公司 一种tlr7激动剂的马来酸盐、其晶型c、晶型d、晶型e、制备方法和用途

Also Published As

Publication number Publication date
CN108602832A (zh) 2018-09-28
EP3412673B1 (en) 2020-11-25
UA124100C2 (uk) 2021-07-21
PH12018501642B1 (en) 2019-06-03
MY190551A (en) 2022-04-27
JP6877449B2 (ja) 2021-05-26
CN107043378A (zh) 2017-08-15
CA3013520A1 (en) 2017-08-10
US20190040072A1 (en) 2019-02-07
LT3412673T (lt) 2021-03-10
KR20180104724A (ko) 2018-09-21
CL2018002094A1 (es) 2018-12-07
SG11201806685VA (en) 2018-09-27
CN108602832B (zh) 2020-10-09
IL260999B (en) 2021-02-28
SI3412673T1 (sl) 2021-04-30
US20200239484A1 (en) 2020-07-30
AU2017214134A1 (en) 2018-08-23
AR107549A1 (es) 2018-05-09
EA034581B1 (ru) 2020-02-21
MX374298B (es) 2025-03-06
PL3412673T3 (pl) 2021-07-26
DK3412673T3 (da) 2021-01-18
WO2017133686A1 (zh) 2017-08-10
KR102371500B1 (ko) 2022-03-07
CA3013520C (en) 2022-07-19
EP3412673A1 (en) 2018-12-12
HUE053455T2 (hu) 2021-06-28
EA201891769A1 (ru) 2019-04-30
JP2019505531A (ja) 2019-02-28
TW201728590A (zh) 2017-08-16
US10654856B2 (en) 2020-05-19
BR112018015879B1 (pt) 2024-02-15
HRP20210103T1 (hr) 2021-03-05
ES2852323T3 (es) 2021-09-13
PT3412673T (pt) 2021-02-15
BR112018015879A2 (pt) 2018-12-26
PH12018501642A1 (en) 2019-06-03
MX2018009502A (es) 2018-12-11
HK1259183A1 (zh) 2019-11-29
EP3412673A4 (en) 2019-07-03
AU2017214134B2 (en) 2020-08-27

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