PT3412673T - Método para preparar composto de pirrolo[3,2-d]pirimidina, e intermediários dos mesmos - Google Patents
Método para preparar composto de pirrolo[3,2-d]pirimidina, e intermediários dos mesmosInfo
- Publication number
- PT3412673T PT3412673T PT177470069T PT17747006T PT3412673T PT 3412673 T PT3412673 T PT 3412673T PT 177470069 T PT177470069 T PT 177470069T PT 17747006 T PT17747006 T PT 17747006T PT 3412673 T PT3412673 T PT 3412673T
- Authority
- PT
- Portugal
- Prior art keywords
- intermediates
- pyrimidine compound
- preparing pyrrolo
- pyrrolo
- preparing
- Prior art date
Links
- 239000000543 intermediate Substances 0.000 title 1
- -1 pyrrolo[3,2-d]pyrimidine compound Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610082028.3A CN107043378A (zh) | 2016-02-05 | 2016-02-05 | 一种吡咯并[3,2-d]嘧啶类化合物的制备方法及其中间体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3412673T true PT3412673T (pt) | 2021-02-15 |
Family
ID=59500148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT177470069T PT3412673T (pt) | 2016-02-05 | 2017-02-04 | Método para preparar composto de pirrolo[3,2-d]pirimidina, e intermediários dos mesmos |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US10654856B2 (enExample) |
| EP (1) | EP3412673B1 (enExample) |
| JP (1) | JP6877449B2 (enExample) |
| KR (1) | KR102371500B1 (enExample) |
| CN (2) | CN107043378A (enExample) |
| AR (1) | AR107549A1 (enExample) |
| AU (1) | AU2017214134B2 (enExample) |
| BR (1) | BR112018015879B1 (enExample) |
| CA (1) | CA3013520C (enExample) |
| CL (1) | CL2018002094A1 (enExample) |
| DK (1) | DK3412673T3 (enExample) |
| EA (1) | EA034581B1 (enExample) |
| ES (1) | ES2852323T3 (enExample) |
| HR (1) | HRP20210103T1 (enExample) |
| HU (1) | HUE053455T2 (enExample) |
| IL (1) | IL260999B (enExample) |
| LT (1) | LT3412673T (enExample) |
| MX (1) | MX374298B (enExample) |
| MY (1) | MY190551A (enExample) |
| NZ (1) | NZ744885A (enExample) |
| PH (1) | PH12018501642A1 (enExample) |
| PL (1) | PL3412673T3 (enExample) |
| PT (1) | PT3412673T (enExample) |
| SG (1) | SG11201806685VA (enExample) |
| SI (1) | SI3412673T1 (enExample) |
| TW (1) | TW201728590A (enExample) |
| UA (1) | UA124100C2 (enExample) |
| WO (1) | WO2017133686A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA201891620A1 (ru) | 2016-02-05 | 2019-02-28 | Денали Терапьютикс Инк. | Ингибиторы взаимодействующей с рецептором протеинкиназы 1 |
| CN107043380A (zh) * | 2016-02-05 | 2017-08-15 | 正大天晴药业集团股份有限公司 | 一种tlr7激动剂的马来酸盐、其晶型c、晶型d、晶型e、制备方法和用途 |
| MX2021009496A (es) | 2019-02-08 | 2021-09-08 | Progeneer Inc | Complejo de colesterol-agonista del receptor 7 u 8 tipo larga distancia, y uso del mismo. |
| WO2021177679A1 (ko) | 2020-03-02 | 2021-09-10 | 성균관대학교산학협력단 | 병원균 외벽 성분 기반 생병원체 모방 나노 입자 및 그 제조 방법 |
| EP4194006A4 (en) | 2020-08-04 | 2024-12-04 | Progeneer Inc. | mRNA VACCINE WITH AN ADJUVANT CAPABLE OF KINETIC CONTROL |
| JP2023536954A (ja) | 2020-08-04 | 2023-08-30 | プロジェニア インコーポレイテッド | 活性化部位が一時的に不活性化したトール様受容体７または８作用薬と機能性薬物の結合体およびその用途 |
| US20230355750A1 (en) | 2020-08-04 | 2023-11-09 | Progeneer Inc. | Kinetically acting adjuvant ensemble |
| MX2024008648A (es) | 2022-01-12 | 2024-09-23 | Denali Therapeutics Inc | Formas cristalinas de (s)-5-bencil-n-(5-metil-4-oxo-2,3,4,5-tetrah idropirido [3,2- b][1,4]oxacepin-3-il)-4h-1,2,4-triazol-3-carboxam ida. |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009082247A1 (en) | 2007-12-21 | 2009-07-02 | Industrial Research Limited | Process for preparing immucillins having a methylene link |
| NZ593110A (en) | 2008-12-09 | 2013-06-28 | Gilead Sciences Inc | pteridinone derivatives as MODULATORS OF TOLL-LIKE RECEPTORS |
| MX365114B (es) * | 2012-10-10 | 2019-05-23 | Janssen Sciences Ireland Uc | Derivados pirrolo[3,2-d]pirimidinicos para el tratamiento de infecciones viricas y otras enfermedades. |
| RU2643371C2 (ru) * | 2012-11-20 | 2018-02-01 | ГЛАКСОСМИТКЛАЙН ЭлЭлСи | Новые соединения |
| JP6228223B2 (ja) * | 2012-11-20 | 2017-11-08 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニーＧｌａｘｏＳｍｉｔｈＫｌｉｎｅ ＬＬＣ | 新規化合物 |
| PL3137470T3 (pl) * | 2014-05-01 | 2021-10-11 | Novartis Ag | Związki i kompozycje jako agonisty receptora toll-like 7 |
| PL3190113T3 (pl) * | 2014-08-15 | 2021-10-25 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Związki pirolopirymidynowe stosowane jako agonista TLR7 |
| CN105367576A (zh) | 2014-08-15 | 2016-03-02 | 正大天晴药业集团股份有限公司 | 作为tlr7激动剂的吡咯并嘧啶化合物 |
| BR112018008880B1 (pt) | 2015-11-05 | 2023-01-17 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 7-(tiazol-5-il) pirrolopirimidina, seu uso, e composição farmacêutica |
| CN107043379A (zh) * | 2016-02-05 | 2017-08-15 | 正大天晴药业集团股份有限公司 | 一种tlr7激动剂的晶型a、其制备方法和医药用途 |
| CN107043377A (zh) * | 2016-02-05 | 2017-08-15 | 正大天晴药业集团股份有限公司 | 一种tlr7激动剂的三氟乙酸盐、晶型b及其制备方法、药物组合物和用途 |
| CN107043380A (zh) * | 2016-02-05 | 2017-08-15 | 正大天晴药业集团股份有限公司 | 一种tlr7激动剂的马来酸盐、其晶型c、晶型d、晶型e、制备方法和用途 |
-
2016
- 2016-02-05 CN CN201610082028.3A patent/CN107043378A/zh active Pending
-
2017
- 2017-02-03 TW TW106103696A patent/TW201728590A/zh unknown
- 2017-02-04 HR HRP20210103TT patent/HRP20210103T1/hr unknown
- 2017-02-04 ES ES17747006T patent/ES2852323T3/es active Active
- 2017-02-04 CA CA3013520A patent/CA3013520C/en active Active
- 2017-02-04 US US16/075,300 patent/US10654856B2/en active Active
- 2017-02-04 JP JP2018540720A patent/JP6877449B2/ja active Active
- 2017-02-04 PT PT177470069T patent/PT3412673T/pt unknown
- 2017-02-04 KR KR1020187024628A patent/KR102371500B1/ko active Active
- 2017-02-04 EA EA201891769A patent/EA034581B1/ru not_active IP Right Cessation
- 2017-02-04 MX MX2018009502A patent/MX374298B/es active IP Right Grant
- 2017-02-04 MY MYPI2018702701A patent/MY190551A/en unknown
- 2017-02-04 SG SG11201806685VA patent/SG11201806685VA/en unknown
- 2017-02-04 NZ NZ744885A patent/NZ744885A/en unknown
- 2017-02-04 AU AU2017214134A patent/AU2017214134B2/en active Active
- 2017-02-04 WO PCT/CN2017/072893 patent/WO2017133686A1/zh not_active Ceased
- 2017-02-04 BR BR112018015879-8A patent/BR112018015879B1/pt active IP Right Grant
- 2017-02-04 SI SI201730605T patent/SI3412673T1/sl unknown
- 2017-02-04 UA UAA201809087A patent/UA124100C2/uk unknown
- 2017-02-04 CN CN201780009748.XA patent/CN108602832B/zh active Active
- 2017-02-04 HU HUE17747006A patent/HUE053455T2/hu unknown
- 2017-02-04 DK DK17747006.9T patent/DK3412673T3/da active
- 2017-02-04 LT LTEP17747006.9T patent/LT3412673T/lt unknown
- 2017-02-04 EP EP17747006.9A patent/EP3412673B1/en active Active
- 2017-02-04 PL PL17747006T patent/PL3412673T3/pl unknown
- 2017-02-06 AR ARP170100298A patent/AR107549A1/es active IP Right Grant
-
2018
- 2018-08-02 PH PH12018501642A patent/PH12018501642A1/en unknown
- 2018-08-03 CL CL2018002094A patent/CL2018002094A1/es unknown
- 2018-08-05 IL IL260999A patent/IL260999B/en active IP Right Grant
-
2020
- 2020-04-13 US US16/847,394 patent/US20200239484A1/en not_active Abandoned
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