NZ598242A - Triazolopyridine compound, and action thereof as prolyl hydroxylase inhibitor and erythropoietin production inducer - Google Patents

Triazolopyridine compound, and action thereof as prolyl hydroxylase inhibitor and erythropoietin production inducer

Info

Publication number
NZ598242A
NZ598242A NZ598242A NZ59824210A NZ598242A NZ 598242 A NZ598242 A NZ 598242A NZ 598242 A NZ598242 A NZ 598242A NZ 59824210 A NZ59824210 A NZ 59824210A NZ 598242 A NZ598242 A NZ 598242A
Authority
NZ
New Zealand
Prior art keywords
erythropoietin production
compound
prolyl hydroxylase
action
hydroxylase inhibitor
Prior art date
Application number
NZ598242A
Other languages
English (en)
Inventor
Takuya Matsui
Yosuke Ogoshi
Masahiro Yokota
Masakazu Terashita
Ikuo Mitani
Takahiro Hotta
Dai Motoda
Hiroyuki Abe
Kazuhito Ueyama
Takashi Ito
Original Assignee
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tobacco Inc filed Critical Japan Tobacco Inc
Publication of NZ598242A publication Critical patent/NZ598242A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
NZ598242A 2009-07-17 2010-07-16 Triazolopyridine compound, and action thereof as prolyl hydroxylase inhibitor and erythropoietin production inducer NZ598242A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009169565 2009-07-17
US27312709P 2009-07-30 2009-07-30
PCT/JP2010/062037 WO2011007856A1 (ja) 2009-07-17 2010-07-16 トリアゾロピリジン化合物、ならびにそのプロリル水酸化酵素阻害剤およびエリスロポエチン産生誘導剤としての作用

Publications (1)

Publication Number Publication Date
NZ598242A true NZ598242A (en) 2013-09-27

Family

ID=43449466

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ598242A NZ598242A (en) 2009-07-17 2010-07-16 Triazolopyridine compound, and action thereof as prolyl hydroxylase inhibitor and erythropoietin production inducer

Country Status (28)

Country Link
US (3) US8283465B2 (enExample)
EP (3) EP2455381B9 (enExample)
JP (9) JP5021797B2 (enExample)
KR (4) KR101706803B1 (enExample)
CN (1) CN102471337B (enExample)
AR (1) AR077417A1 (enExample)
AU (1) AU2010271732B2 (enExample)
BR (1) BR112012001157A2 (enExample)
CA (1) CA2768505C (enExample)
CO (1) CO6430426A2 (enExample)
DK (1) DK2455381T5 (enExample)
ES (1) ES2477968T3 (enExample)
HR (1) HRP20140705T1 (enExample)
IL (1) IL217541A (enExample)
ME (1) ME01858B (enExample)
MX (1) MX2012000766A (enExample)
MY (1) MY160814A (enExample)
NZ (1) NZ598242A (enExample)
PE (1) PE20120629A1 (enExample)
PL (1) PL2455381T3 (enExample)
PT (1) PT2455381E (enExample)
RS (1) RS53499B1 (enExample)
RU (1) RU2538963C2 (enExample)
SG (1) SG178049A1 (enExample)
SI (1) SI2455381T1 (enExample)
SM (1) SMT201500122B (enExample)
TW (1) TWI485150B (enExample)
WO (1) WO2011007856A1 (enExample)

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JP2018039733A (ja) * 2014-12-22 2018-03-15 株式会社富士薬品 新規複素環誘導体
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CN106146395B (zh) * 2015-03-27 2019-01-01 沈阳三生制药有限责任公司 3-羟基吡啶化合物、其制备方法及其制药用途
JP6814134B2 (ja) * 2015-05-28 2021-01-13 日本たばこ産業株式会社 糖尿病性腎症を治療又は予防する方法
WO2018097254A1 (ja) 2016-11-25 2018-05-31 日本たばこ産業株式会社 トリアゾロピリジン化合物の製造方法
CA3062972C (en) 2017-05-09 2021-09-14 Kind Pharmaceutical Indolizine derivatives and their application in medicine
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CN107739378A (zh) * 2017-11-14 2018-02-27 杭州安道药业有限公司 吲哚嗪衍生物及其在医药上的应用
BR112021004730A2 (pt) 2018-09-13 2021-06-01 Kissei Pharmaceutical Co., Ltd. composto de imidazopiridinona
CN110105355B (zh) * 2019-05-24 2021-09-21 烟台大学 一种1,2,3-三唑-[1,5-a]并喹啉类化合物的制备方法
US20230167108A1 (en) * 2020-03-11 2023-06-01 Kissei Pharmaceutical Co., Ltd. Crystal of imidazopyridinone compound or salt thereof
JP7504822B2 (ja) * 2020-03-12 2024-06-24 キッセイ薬品工業株式会社 イミダゾピリジノン化合物を含む医薬組成物
EP4138825A1 (en) 2020-04-20 2023-03-01 Akebia Therapeutics Inc. Treatment of viral infections, of organ injury, and of related conditions using a hif prolyl hydroxylase inhibitor or a hif-alpha stabilizer
WO2022150623A1 (en) 2021-01-08 2022-07-14 Akebia Therapeutics, Inc. Compounds and composition for the treatment of anemia
CN113387948B (zh) * 2021-02-06 2022-06-10 成都诺和晟泰生物科技有限公司 一种稠环杂芳基衍生物及其药物组合物和治疗方法及用途
TW202313072A (zh) 2021-05-27 2023-04-01 美商凱立克斯生物製藥股份有限公司 檸檬酸鐵之兒科調配物
CN113582843A (zh) * 2021-09-09 2021-11-02 无锡捷化医药科技有限公司 一种5-氯-2-氟-3-羟基苯甲酸乙酯的制备方法
CN116496269B (zh) * 2021-12-02 2025-02-28 苏中药业集团股份有限公司 一种脯氨酰羟化酶抑制剂及其用途
CN114031619A (zh) * 2021-12-17 2022-02-11 山东汇海医药化工有限公司 一种图卡替尼中间体的制备方法
WO2024061172A1 (zh) * 2022-09-19 2024-03-28 苏中药业集团股份有限公司 一种脯氨酰羟化酶抑制剂及其用途
WO2024245389A1 (zh) * 2023-06-02 2024-12-05 苏中药业集团股份有限公司 一种脯氨酰羟化酶抑制剂及其用途
TW202506675A (zh) * 2023-08-08 2025-02-16 美商富曼西公司 用於防治和對抗無脊椎有害生物的連接的雙環化合物
CN117486878A (zh) * 2023-10-27 2024-02-02 扬州市普林斯医药科技有限公司 一种恩那司他的制备方法
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WO2025167738A1 (zh) * 2024-02-05 2025-08-14 深圳信立泰药业股份有限公司 化合物在制备治疗非髓系恶性肿瘤患者的贫血药物中的应用
WO2025167739A1 (zh) * 2024-02-05 2025-08-14 深圳信立泰药业股份有限公司 化合物在制备预防和/或治疗高原病的药物中的应用
CN119039291A (zh) * 2024-09-09 2024-11-29 南京药坦生物科技有限公司 一种恩那度司他中间体及其制备方法

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Also Published As

Publication number Publication date
KR20170018105A (ko) 2017-02-15
CO6430426A2 (es) 2012-04-30
JP2017214404A (ja) 2017-12-07
KR20230165366A (ko) 2023-12-05
ME01858B (me) 2014-12-20
RU2012105467A (ru) 2013-08-27
CA2768505A1 (en) 2011-01-20
MX2012000766A (es) 2012-02-08
ES2477968T3 (es) 2014-07-18
HK1168346A1 (en) 2012-12-28
CN102471337B (zh) 2014-12-10
CA2768505C (en) 2018-06-12
KR20120051704A (ko) 2012-05-22
PL2455381T3 (pl) 2014-10-31
SMT201500122B (it) 2015-07-09
JP2022126843A (ja) 2022-08-30
MY160814A (en) 2017-03-31
JP2016040321A (ja) 2016-03-24
JP2015003933A (ja) 2015-01-08
HRP20140705T1 (hr) 2014-09-12
EP2455381A4 (en) 2012-12-12
DK2455381T5 (en) 2015-02-09
AU2010271732B2 (en) 2016-08-25
PE20120629A1 (es) 2012-05-30
US8283465B2 (en) 2012-10-09
EP2455381A1 (en) 2012-05-23
US20130096155A1 (en) 2013-04-18
EP2746282A1 (en) 2014-06-25
KR101706803B1 (ko) 2017-02-14
AR077417A1 (es) 2011-08-24
ES2477968T9 (es) 2014-11-13
IL217541A (en) 2014-07-31
SI2455381T1 (sl) 2014-08-29
RS53499B1 (sr) 2015-02-27
RU2538963C2 (ru) 2015-01-10
EP2455381B1 (en) 2014-05-28
CN102471337A (zh) 2012-05-23
SG178049A1 (en) 2012-03-29
AU2010271732A1 (en) 2012-03-08
JP6434575B2 (ja) 2018-12-05
US20160145254A1 (en) 2016-05-26
WO2011007856A1 (ja) 2011-01-20
TWI485150B (zh) 2015-05-21
JP2012144571A (ja) 2012-08-02
US20110077267A1 (en) 2011-03-31
EP3594213A1 (en) 2020-01-15
JP2020111612A (ja) 2020-07-27
KR20180042443A (ko) 2018-04-25
IL217541A0 (en) 2012-02-29
PT2455381E (pt) 2014-06-24
JP2019019144A (ja) 2019-02-07
JP2024091878A (ja) 2024-07-05
JP2011037841A (ja) 2011-02-24
JP5021797B2 (ja) 2012-09-12
TW201105671A (en) 2011-02-16
DK2455381T3 (da) 2014-07-21
BR112012001157A2 (pt) 2016-02-23
KR101850661B1 (ko) 2018-04-19
EP2455381B9 (en) 2014-10-22

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