PT2455381E - Composto de triazolopiridina e sua acção como inibidor da prolil-hidroxilase e indutor da produção de eritropoietina - Google Patents

Composto de triazolopiridina e sua acção como inibidor da prolil-hidroxilase e indutor da produção de eritropoietina Download PDF

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Publication number
PT2455381E
PT2455381E PT107999146T PT10799914T PT2455381E PT 2455381 E PT2455381 E PT 2455381E PT 107999146 T PT107999146 T PT 107999146T PT 10799914 T PT10799914 T PT 10799914T PT 2455381 E PT2455381 E PT 2455381E
Authority
PT
Portugal
Prior art keywords
action
prolyl hydroxylase
hydroxylase inhibitor
erythropoietin production
production inducer
Prior art date
Application number
PT107999146T
Other languages
English (en)
Portuguese (pt)
Inventor
Hiroyuki Abe
Ikuo Mitani
Yosuke Ogoshi
Takuya Matsui
Masahiro Yokota
Masakazu Terashita
Dai Motoda
Kazuhito Ueyama
Takahiro Hotta
Takashi Ito
Original Assignee
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tobacco Inc filed Critical Japan Tobacco Inc
Publication of PT2455381E publication Critical patent/PT2455381E/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
PT107999146T 2009-07-17 2010-07-16 Composto de triazolopiridina e sua acção como inibidor da prolil-hidroxilase e indutor da produção de eritropoietina PT2455381E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009169565 2009-07-17
US27312709P 2009-07-30 2009-07-30

Publications (1)

Publication Number Publication Date
PT2455381E true PT2455381E (pt) 2014-06-24

Family

ID=43449466

Family Applications (1)

Application Number Title Priority Date Filing Date
PT107999146T PT2455381E (pt) 2009-07-17 2010-07-16 Composto de triazolopiridina e sua acção como inibidor da prolil-hidroxilase e indutor da produção de eritropoietina

Country Status (28)

Country Link
US (3) US8283465B2 (enExample)
EP (3) EP3594213A1 (enExample)
JP (9) JP5021797B2 (enExample)
KR (4) KR20180042443A (enExample)
CN (1) CN102471337B (enExample)
AR (1) AR077417A1 (enExample)
AU (1) AU2010271732B2 (enExample)
BR (1) BR112012001157A2 (enExample)
CA (1) CA2768505C (enExample)
CO (1) CO6430426A2 (enExample)
DK (1) DK2455381T5 (enExample)
ES (1) ES2477968T3 (enExample)
HR (1) HRP20140705T1 (enExample)
IL (1) IL217541A (enExample)
ME (1) ME01858B (enExample)
MX (1) MX2012000766A (enExample)
MY (1) MY160814A (enExample)
NZ (1) NZ598242A (enExample)
PE (1) PE20120629A1 (enExample)
PL (1) PL2455381T3 (enExample)
PT (1) PT2455381E (enExample)
RS (1) RS53499B1 (enExample)
RU (1) RU2538963C2 (enExample)
SG (1) SG178049A1 (enExample)
SI (1) SI2455381T1 (enExample)
SM (1) SMT201500122B (enExample)
TW (1) TWI485150B (enExample)
WO (1) WO2011007856A1 (enExample)

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CN110105355B (zh) * 2019-05-24 2021-09-21 烟台大学 一种1,2,3-三唑-[1,5-a]并喹啉类化合物的制备方法
JP7566008B2 (ja) * 2020-03-11 2024-10-11 キッセイ薬品工業株式会社 イミダゾピリジノン化合物又はその塩の結晶
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CN113387948B (zh) * 2021-02-06 2022-06-10 成都诺和晟泰生物科技有限公司 一种稠环杂芳基衍生物及其药物组合物和治疗方法及用途
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CN113582843A (zh) * 2021-09-09 2021-11-02 无锡捷化医药科技有限公司 一种5-氯-2-氟-3-羟基苯甲酸乙酯的制备方法
CN116496269B (zh) * 2021-12-02 2025-02-28 苏中药业集团股份有限公司 一种脯氨酰羟化酶抑制剂及其用途
CN114031619A (zh) * 2021-12-17 2022-02-11 山东汇海医药化工有限公司 一种图卡替尼中间体的制备方法
CN119948024A (zh) * 2022-09-19 2025-05-06 苏中药业集团股份有限公司 一种脯氨酰羟化酶抑制剂及其用途
WO2024245389A1 (zh) * 2023-06-02 2024-12-05 苏中药业集团股份有限公司 一种脯氨酰羟化酶抑制剂及其用途
TW202506675A (zh) * 2023-08-08 2025-02-16 美商富曼西公司 用於防治和對抗無脊椎有害生物的連接的雙環化合物
CN117486878A (zh) * 2023-10-27 2024-02-02 扬州市普林斯医药科技有限公司 一种恩那司他的制备方法
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CN119039291A (zh) * 2024-09-09 2024-11-29 南京药坦生物科技有限公司 一种恩那度司他中间体及其制备方法

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Also Published As

Publication number Publication date
TWI485150B (zh) 2015-05-21
JP2020111612A (ja) 2020-07-27
JP2024091878A (ja) 2024-07-05
KR20120051704A (ko) 2012-05-22
JP2019019144A (ja) 2019-02-07
NZ598242A (en) 2013-09-27
AU2010271732A1 (en) 2012-03-08
US20160145254A1 (en) 2016-05-26
MY160814A (en) 2017-03-31
ES2477968T3 (es) 2014-07-18
IL217541A0 (en) 2012-02-29
RS53499B1 (sr) 2015-02-27
KR101706803B1 (ko) 2017-02-14
SMT201500122B (it) 2015-07-09
EP3594213A1 (en) 2020-01-15
KR20170018105A (ko) 2017-02-15
EP2455381A4 (en) 2012-12-12
ME01858B (me) 2014-12-20
CA2768505C (en) 2018-06-12
TW201105671A (en) 2011-02-16
JP2012144571A (ja) 2012-08-02
ES2477968T9 (es) 2014-11-13
WO2011007856A1 (ja) 2011-01-20
MX2012000766A (es) 2012-02-08
CN102471337A (zh) 2012-05-23
DK2455381T5 (en) 2015-02-09
PE20120629A1 (es) 2012-05-30
US20110077267A1 (en) 2011-03-31
BR112012001157A2 (pt) 2016-02-23
EP2455381A1 (en) 2012-05-23
JP5021797B2 (ja) 2012-09-12
EP2455381B9 (en) 2014-10-22
PL2455381T3 (pl) 2014-10-31
JP2017214404A (ja) 2017-12-07
KR20180042443A (ko) 2018-04-25
JP2015003933A (ja) 2015-01-08
RU2012105467A (ru) 2013-08-27
US8283465B2 (en) 2012-10-09
CA2768505A1 (en) 2011-01-20
EP2746282A1 (en) 2014-06-25
DK2455381T3 (da) 2014-07-21
AU2010271732B2 (en) 2016-08-25
JP2016040321A (ja) 2016-03-24
KR20230165366A (ko) 2023-12-05
RU2538963C2 (ru) 2015-01-10
JP2022126843A (ja) 2022-08-30
CO6430426A2 (es) 2012-04-30
US20130096155A1 (en) 2013-04-18
EP2455381B1 (en) 2014-05-28
HK1168346A1 (en) 2012-12-28
JP2011037841A (ja) 2011-02-24
CN102471337B (zh) 2014-12-10
IL217541A (en) 2014-07-31
JP6434575B2 (ja) 2018-12-05
SI2455381T1 (sl) 2014-08-29
AR077417A1 (es) 2011-08-24
HRP20140705T1 (hr) 2014-09-12
KR101850661B1 (ko) 2018-04-19
SG178049A1 (en) 2012-03-29

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