MA32375B1 - Derives de 5-hydroxymethyl-oxazolidine-2-one pour le traitement de maladies intestinales bacteriennes - Google Patents
Derives de 5-hydroxymethyl-oxazolidine-2-one pour le traitement de maladies intestinales bacteriennesInfo
- Publication number
- MA32375B1 MA32375B1 MA33391A MA33391A MA32375B1 MA 32375 B1 MA32375 B1 MA 32375B1 MA 33391 A MA33391 A MA 33391A MA 33391 A MA33391 A MA 33391A MA 32375 B1 MA32375 B1 MA 32375B1
- Authority
- MA
- Morocco
- Prior art keywords
- treatment
- oxazolidine
- hydroxymethyl
- derivatives
- intestinal diseases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
La présente invention concerne des composés de formule i (i) dans laquelle a est n ou ch ; et n vaut 0 ou 1 ; ou leurs sels pharmaceutiquement acceptables, pour la prévention ou le traitement de maladies intestinales qui sont provoquées par des bactéries choisies parmi clostridium difficile, clostridium perfringens ou staphylococcus aureus.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IBPCT/IB2008/051854 | 2008-05-09 | ||
PCT/IB2009/051896 WO2009136379A1 (fr) | 2008-05-09 | 2009-05-08 | Dérivés de 5-hydroxyméthyl-oxazolidine-2-one pour le traitement de maladies intestinales bactériennes |
Publications (1)
Publication Number | Publication Date |
---|---|
MA32375B1 true MA32375B1 (fr) | 2011-06-01 |
Family
ID=40955145
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA33391A MA32375B1 (fr) | 2008-05-09 | 2010-12-03 | Derives de 5-hydroxymethyl-oxazolidine-2-one pour le traitement de maladies intestinales bacteriennes |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP2296651B1 (fr) |
JP (1) | JP4819980B2 (fr) |
KR (1) | KR101283222B1 (fr) |
CN (1) | CN102014903B (fr) |
AR (1) | AR071762A1 (fr) |
AU (1) | AU2009245351B2 (fr) |
BR (1) | BRPI0911991B8 (fr) |
CA (1) | CA2723232C (fr) |
CY (1) | CY1113197T1 (fr) |
DK (1) | DK2296651T3 (fr) |
ES (1) | ES2390405T3 (fr) |
HK (1) | HK1155086A1 (fr) |
HR (1) | HRP20120791T1 (fr) |
IL (1) | IL209105A0 (fr) |
MA (1) | MA32375B1 (fr) |
MX (1) | MX2010011918A (fr) |
MY (1) | MY156304A (fr) |
NZ (1) | NZ589734A (fr) |
PL (1) | PL2296651T3 (fr) |
PT (1) | PT2296651E (fr) |
RU (1) | RU2527769C2 (fr) |
SI (1) | SI2296651T1 (fr) |
TW (1) | TWI447115B (fr) |
WO (1) | WO2009136379A1 (fr) |
ZA (1) | ZA201008841B (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003031443A1 (fr) | 2001-10-04 | 2003-04-17 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Antibiotiques a action duale renfermant une oxazolidinone et une quinolone ou une fraction de naphthyridinone |
WO2004096221A1 (fr) | 2003-04-30 | 2004-11-11 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Utilisation d'antibiotiques hybrides d'oxazolidinone-quinoleine destines au traitement de l'anthrax et d'autres infections |
DE10340485B4 (de) | 2003-09-03 | 2015-05-13 | Morphochem AG Aktiengesellschaft für kombinatorische Chemie | Verfahren zur Herstellung von Oxazolidinon-Chinolon Hybriden |
CA2549675C (fr) | 2003-12-18 | 2012-11-20 | Morphochem Aktiengesellschaft Fur Kombinatorische Chemie | Antibiotiques hybrides a base d'oxazolidinone-quinolone |
US8158797B2 (en) | 2003-12-18 | 2012-04-17 | Morphochem Aktiengesellschaft Fur Kombinatorische Chemie | Oxazolidinone-quinolone hybrid antibiotics |
WO2014191075A1 (fr) * | 2013-05-28 | 2014-12-04 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Antibactériens hybrides à base d'oxazolidinone-quinolone pour le traitement parentéral ou la prophylaxie de maladies bactériennes |
US9993469B2 (en) * | 2013-05-28 | 2018-06-12 | Morphochem Aktiengesellschaft Für Kombinatorishe Chemie | Combination therapy comprising oxazolidinone-quinolones for use in treating bacterial infections |
US10087171B2 (en) | 2016-12-19 | 2018-10-02 | Actelion Pharmaceuticals Ltd | Crystalline forms of cadazolid |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU1156597A3 (ru) * | 1982-04-28 | 1985-05-15 | Е.И.Дюпон Де Немур Энд Компани (Фирма) | Способ получени производных 3-( @ -алкилсульфонилфенил)оксазолидинона или их фармацевтически приемлемых кислотно-аддитивных солей |
US4461773A (en) * | 1982-09-15 | 1984-07-24 | E. I. Dupont De Nemours And Company | P-Oxooxazolidinylbenzene compounds as antibacterial agents |
US6689769B2 (en) * | 2000-12-21 | 2004-02-10 | Pharmacia & Upjohn Company | Antimicrobial quinolone derivatives and use of the same to treat bacterial infections |
ES2186550B2 (es) * | 2001-06-27 | 2003-11-16 | Vita Lab | Nuevos derivados de oxazolidinonas como antibacterianos. |
WO2003031443A1 (fr) * | 2001-10-04 | 2003-04-17 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Antibiotiques a action duale renfermant une oxazolidinone et une quinolone ou une fraction de naphthyridinone |
WO2004096221A1 (fr) * | 2003-04-30 | 2004-11-11 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Utilisation d'antibiotiques hybrides d'oxazolidinone-quinoleine destines au traitement de l'anthrax et d'autres infections |
KR100854211B1 (ko) | 2003-12-18 | 2008-08-26 | 동아제약주식회사 | 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물 |
DK2086968T3 (da) * | 2006-11-10 | 2012-03-19 | Actelion Pharmaceuticals Ltd | 5-hydroxymethyl-oxazolidin-2-on-derivater |
-
2009
- 2009-05-08 PL PL09742552T patent/PL2296651T3/pl unknown
- 2009-05-08 EP EP09742552A patent/EP2296651B1/fr active Active
- 2009-05-08 KR KR1020107025774A patent/KR101283222B1/ko active IP Right Grant
- 2009-05-08 CA CA2723232A patent/CA2723232C/fr active Active
- 2009-05-08 SI SI200930338T patent/SI2296651T1/sl unknown
- 2009-05-08 CN CN2009801143512A patent/CN102014903B/zh active Active
- 2009-05-08 ES ES09742552T patent/ES2390405T3/es active Active
- 2009-05-08 BR BRPI0911991A patent/BRPI0911991B8/pt active IP Right Grant
- 2009-05-08 WO PCT/IB2009/051896 patent/WO2009136379A1/fr active Application Filing
- 2009-05-08 DK DK09742552.4T patent/DK2296651T3/da active
- 2009-05-08 AU AU2009245351A patent/AU2009245351B2/en active Active
- 2009-05-08 RU RU2010149994/15A patent/RU2527769C2/ru active
- 2009-05-08 PT PT09742552T patent/PT2296651E/pt unknown
- 2009-05-08 JP JP2011508044A patent/JP4819980B2/ja active Active
- 2009-05-08 MX MX2010011918A patent/MX2010011918A/es active IP Right Grant
- 2009-05-08 TW TW098115466A patent/TWI447115B/zh active
- 2009-05-08 AR ARP090101672A patent/AR071762A1/es unknown
- 2009-05-08 NZ NZ589734A patent/NZ589734A/xx unknown
- 2009-05-08 MY MYPI2010005226A patent/MY156304A/en unknown
-
2010
- 2010-11-04 IL IL209105A patent/IL209105A0/en active IP Right Grant
- 2010-12-03 MA MA33391A patent/MA32375B1/fr unknown
- 2010-12-08 ZA ZA2010/08841A patent/ZA201008841B/en unknown
-
2011
- 2011-09-06 HK HK11109417.3A patent/HK1155086A1/xx unknown
-
2012
- 2012-10-03 HR HRP20120791AT patent/HRP20120791T1/hr unknown
- 2012-10-12 CY CY20121100949T patent/CY1113197T1/el unknown
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