AR071762A1 - Derivados 5-hidroximetil-oxazolidin-2-ona para el tratamiento de enfermedades intestinales bacteriales - Google Patents

Derivados 5-hidroximetil-oxazolidin-2-ona para el tratamiento de enfermedades intestinales bacteriales

Info

Publication number
AR071762A1
AR071762A1 ARP090101672A ARP090101672A AR071762A1 AR 071762 A1 AR071762 A1 AR 071762A1 AR P090101672 A ARP090101672 A AR P090101672A AR P090101672 A ARP090101672 A AR P090101672A AR 071762 A1 AR071762 A1 AR 071762A1
Authority
AR
Argentina
Prior art keywords
treatment
hydroximethyl
oxazolidin
intestinal diseases
bacterial intestinal
Prior art date
Application number
ARP090101672A
Other languages
English (en)
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40955145&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR071762(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of AR071762A1 publication Critical patent/AR071762A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Se relaciona con los compuestos de formula (1) en los cuales A es N o CH; y n es 0 o 1; o con las sales farmaceuticamente aceptables de los mismos, para la prevencion o el tratamiento de enfermedades intestinales que son causadas por bacterias seleccionadas de entre Clostridium difficile, Clostridium perfringens o Staphylococcus aureus.
ARP090101672A 2008-05-09 2009-05-08 Derivados 5-hidroximetil-oxazolidin-2-ona para el tratamiento de enfermedades intestinales bacteriales AR071762A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IBPCT/IB2008/051854 2008-05-09

Publications (1)

Publication Number Publication Date
AR071762A1 true AR071762A1 (es) 2010-07-14

Family

ID=40955145

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP090101672A AR071762A1 (es) 2008-05-09 2009-05-08 Derivados 5-hidroximetil-oxazolidin-2-ona para el tratamiento de enfermedades intestinales bacteriales

Country Status (25)

Country Link
EP (1) EP2296651B1 (es)
JP (1) JP4819980B2 (es)
KR (1) KR101283222B1 (es)
CN (1) CN102014903B (es)
AR (1) AR071762A1 (es)
AU (1) AU2009245351B2 (es)
BR (1) BRPI0911991B8 (es)
CA (1) CA2723232C (es)
CY (1) CY1113197T1 (es)
DK (1) DK2296651T3 (es)
ES (1) ES2390405T3 (es)
HK (1) HK1155086A1 (es)
HR (1) HRP20120791T1 (es)
IL (1) IL209105A0 (es)
MA (1) MA32375B1 (es)
MX (1) MX2010011918A (es)
MY (1) MY156304A (es)
NZ (1) NZ589734A (es)
PL (1) PL2296651T3 (es)
PT (1) PT2296651E (es)
RU (1) RU2527769C2 (es)
SI (1) SI2296651T1 (es)
TW (1) TWI447115B (es)
WO (1) WO2009136379A1 (es)
ZA (1) ZA201008841B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003031443A1 (en) 2001-10-04 2003-04-17 Morphochem Aktiengesellschaft für kombinatorische Chemie Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety
RU2351335C2 (ru) 2003-04-30 2009-04-10 Морфохем Акциенгезельшафт Фюр Комбинаторише Хеми Применение оксазолидинон-хинолиновых гибридных антибиотиков для лечения сибирской язвы и других инфекций
DE10340485B4 (de) 2003-09-03 2015-05-13 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Verfahren zur Herstellung von Oxazolidinon-Chinolon Hybriden
SI1709044T2 (sl) 2003-12-18 2014-02-28 Morphochem Aktiengesellschaft Fuer Kombinatorische Chemie Oksazolidinon-kinolonski hibridni antibiotiki
US8158797B2 (en) 2003-12-18 2012-04-17 Morphochem Aktiengesellschaft Fur Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
AU2014273471B2 (en) * 2013-05-28 2019-10-03 Morphochem Aktiengesellschaft Fur Kombinatorische Chemie Combination therapy comprising oxazolidinone-quinolones for use in treating bacterial infections
DK3003289T3 (da) 2013-05-28 2019-05-20 Morphochem Aktiengesellschaft Fuer Komb Chemie Indgivelse af antibakteriele oxazolidinon-quinolon-hybrid-midler
US10087171B2 (en) 2016-12-19 2018-10-02 Actelion Pharmaceuticals Ltd Crystalline forms of cadazolid

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1156597A3 (ru) * 1982-04-28 1985-05-15 Е.И.Дюпон Де Немур Энд Компани (Фирма) Способ получени производных 3-( @ -алкилсульфонилфенил)оксазолидинона или их фармацевтически приемлемых кислотно-аддитивных солей
US4461773A (en) * 1982-09-15 1984-07-24 E. I. Dupont De Nemours And Company P-Oxooxazolidinylbenzene compounds as antibacterial agents
EP1349853B1 (en) * 2000-12-21 2006-03-08 Pharmacia & Upjohn Company LLC Antimicrobial quinolone derivatives and use of the same to treat bacterial infections
ES2186550B2 (es) * 2001-06-27 2003-11-16 Vita Lab Nuevos derivados de oxazolidinonas como antibacterianos.
WO2003031443A1 (en) * 2001-10-04 2003-04-17 Morphochem Aktiengesellschaft für kombinatorische Chemie Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety
RU2351335C2 (ru) * 2003-04-30 2009-04-10 Морфохем Акциенгезельшафт Фюр Комбинаторише Хеми Применение оксазолидинон-хинолиновых гибридных антибиотиков для лечения сибирской язвы и других инфекций
KR100854211B1 (ko) * 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
CL2007003232A1 (es) * 2006-11-10 2008-06-27 Actelion Pharmaceuticals Ltd Compuestos derivados de 5-hidroximetil oxazolidin-2-ona; composicion farmaceutica que contiene a dichos compuestos; y su uso para tratar y prevenir infecciones bacterianas.

Also Published As

Publication number Publication date
BRPI0911991B8 (pt) 2021-05-25
CN102014903B (zh) 2013-07-10
AU2009245351A1 (en) 2009-11-12
KR20100137569A (ko) 2010-12-30
CA2723232C (en) 2016-08-02
TWI447115B (zh) 2014-08-01
BRPI0911991A2 (pt) 2018-02-27
MA32375B1 (fr) 2011-06-01
WO2009136379A1 (en) 2009-11-12
TW200948808A (en) 2009-12-01
SI2296651T1 (sl) 2012-10-30
DK2296651T3 (da) 2012-09-24
EP2296651B1 (en) 2012-07-18
JP4819980B2 (ja) 2011-11-24
EP2296651A1 (en) 2011-03-23
JP2011519914A (ja) 2011-07-14
BRPI0911991B1 (pt) 2020-09-15
CA2723232A1 (en) 2009-11-12
CN102014903A (zh) 2011-04-13
MX2010011918A (es) 2010-11-26
ZA201008841B (en) 2012-05-30
NZ589734A (en) 2012-11-30
IL209105A0 (en) 2016-09-29
RU2527769C2 (ru) 2014-09-10
HK1155086A1 (en) 2012-05-11
AU2009245351B2 (en) 2015-01-22
PT2296651E (pt) 2012-10-01
MY156304A (en) 2016-01-29
ES2390405T3 (es) 2012-11-12
PL2296651T3 (pl) 2012-12-31
HRP20120791T1 (hr) 2012-11-30
RU2010149994A (ru) 2012-06-20
KR101283222B1 (ko) 2013-07-11
CY1113197T1 (el) 2016-04-13

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