NZ219068A - Dihydrobenzofuran- and chromancarboxamide derivatives and neuroleptic compositions - Google Patents

Dihydrobenzofuran- and chromancarboxamide derivatives and neuroleptic compositions

Info

Publication number
NZ219068A
NZ219068A NZ219068A NZ21906887A NZ219068A NZ 219068 A NZ219068 A NZ 219068A NZ 219068 A NZ219068 A NZ 219068A NZ 21906887 A NZ21906887 A NZ 21906887A NZ 219068 A NZ219068 A NZ 219068A
Authority
NZ
New Zealand
Prior art keywords
methyl
carboxamide
water
formula
group
Prior art date
Application number
NZ219068A
Other languages
English (en)
Inventor
Jacqueline Franceschini
Josette Margarit
Original Assignee
Delagrange Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delagrange Lab filed Critical Delagrange Lab
Publication of NZ219068A publication Critical patent/NZ219068A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
  • Furan Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polyamides (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NZ219068A 1986-01-30 1987-01-27 Dihydrobenzofuran- and chromancarboxamide derivatives and neuroleptic compositions NZ219068A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8601279A FR2593504B1 (fr) 1986-01-30 1986-01-30 Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques

Publications (1)

Publication Number Publication Date
NZ219068A true NZ219068A (en) 1990-12-21

Family

ID=9331629

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ219068A NZ219068A (en) 1986-01-30 1987-01-27 Dihydrobenzofuran- and chromancarboxamide derivatives and neuroleptic compositions

Country Status (40)

Country Link
US (1) US5006570A (en.html)
EP (1) EP0231139B1 (en.html)
JP (1) JPS62277376A (en.html)
KR (1) KR870007160A (en.html)
CN (2) CN1016420B (en.html)
AT (1) ATE70063T1 (en.html)
AU (1) AU593605B2 (en.html)
BE (1) BE1000164A5 (en.html)
BG (1) BG46600A3 (en.html)
CA (1) CA1300161C (en.html)
CH (1) CH670827A5 (en.html)
CS (2) CS264288B2 (en.html)
DD (1) DD260065A5 (en.html)
DE (2) DE3702005A1 (en.html)
DK (1) DK46987A (en.html)
ES (2) ES2003671A6 (en.html)
FI (1) FI870347A7 (en.html)
FR (1) FR2593504B1 (en.html)
GB (1) GB2187188B (en.html)
GR (2) GR870134B (en.html)
HU (1) HU206107B (en.html)
IE (1) IE870128L (en.html)
IL (1) IL81299A (en.html)
IN (2) IN164389B (en.html)
IS (1) IS1446B6 (en.html)
IT (1) IT1205729B (en.html)
LU (1) LU86747A1 (en.html)
MA (1) MA20861A1 (en.html)
NO (1) NO168582C (en.html)
NZ (1) NZ219068A (en.html)
OA (1) OA08472A (en.html)
PH (1) PH23392A (en.html)
PL (2) PL152404B1 (en.html)
PT (1) PT84224B (en.html)
SU (2) SU1609451A3 (en.html)
TN (1) TNSN87012A1 (en.html)
YU (1) YU46185B (en.html)
ZA (1) ZA87552B (en.html)
ZM (1) ZM987A1 (en.html)
ZW (1) ZW1387A1 (en.html)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2611715B1 (fr) * 1987-02-27 1989-05-12 Adir Nouveaux acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2611713B1 (fr) * 1987-02-27 1990-11-30 Adir Nouveaux derives de l'acide (dihydro-2,3 oxo-2 benzofurannyl-3)-2 acetique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
US5374637A (en) * 1989-03-22 1994-12-20 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives
JP2726306B2 (ja) * 1989-04-14 1998-03-11 本田技研工業株式会社 車両の前後輪操舵装置
US5122361A (en) * 1989-04-17 1992-06-16 Trustees Of The University Of Pennsylvania Dopamine receptor ligands and imaging agents
EP0412939A3 (en) * 1989-08-11 1991-09-04 Ciba-Geigy Ag Certain benzopyran and benzothiopyran derivatives
US5420151A (en) * 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
US5616610A (en) * 1989-12-22 1997-04-01 Astra Aktiebolag (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans
GB9005014D0 (en) 1990-03-06 1990-05-02 Janssen Pharmaceutica Nv N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives
WO1991017144A1 (en) * 1990-05-02 1991-11-14 Yoshitomi Pharmaceutical Industries, Ltd. Amide compound, pharmaceutical use thereof and novel 1-substituted pyrrolidinemethyl-amines
US5114947A (en) * 1990-12-27 1992-05-19 Erbamont Inc. Method for alleviating anxiety using benzobicyclic carboxamides
MA22647A1 (fr) * 1991-09-14 1993-04-01 Smithkline Beecham Plc Procede de preparation d'un ester ou d'un amide d'un nouveau produit .
NZ246915A (en) * 1992-02-06 1996-05-28 Smithkline Beecham Plc Benzopyran, benzothiopyran and benzofuran derivatives, preparation and pharmaceutical compositions thereof
WO1994008994A1 (en) * 1992-10-13 1994-04-28 Smithkline Beecham Plc Heterocyclic -esters or -amides used as 5-ht4 receptor antagonists
US6127379A (en) * 1993-02-01 2000-10-03 Smithkline Beecham P.L.C. Benzopyran, benzothiopyran and benzofuran derivatives as 5-HT4 antagonists
RU2129556C1 (ru) * 1993-08-19 1999-04-27 Жансен Фармасетика Н.В. Производное дигидробензопирана, обладающее сосудосуживающим действием, промежуточные соединения, способы получения, фармацевтическая композиция и способ ее получения
JP2999669B2 (ja) * 1993-08-24 2000-01-17 株式会社三和化学研究所 ベンゾ［ｂ］フランカルボキサミド誘導体、その製法及び用途
JPH0820586A (ja) * 1994-07-05 1996-01-23 Sanwa Kagaku Kenkyusho Co Ltd １−アザビシクロ［３．３．０］オクタン誘導体、その塩及び製法並びに用途
JPH0873463A (ja) 1994-07-05 1996-03-19 Sanwa Kagaku Kenkyusho Co Ltd ベンゾピランカルボキサミド誘導体、その塩及び製法並びに用途
TW490465B (en) * 1994-11-24 2002-06-11 Janssen Pharmaceutica Nv Enterokinetic benzamide, the preparation process and the pharmaceutical compositions thereof
TW475930B (en) * 1995-04-24 2002-02-11 Novartis Ag Novel compound, its use and pharmaceutical composition comprising it

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0135545A1 (en) * 1983-02-19 1985-04-03 Beecham Group Plc Azabicycloalkyl benzamide and anilide derivatives
JPS59186969A (ja) * 1983-04-08 1984-10-23 Yoshitomi Pharmaceut Ind Ltd ベンゾフラン−およびベンゾピランカルボキサミド誘導体
CA1297877C (en) * 1983-12-22 1992-03-24 Daniel Lednicer Benzofurancarboxamides useful as antiemetic or antipsychotic agents
JPS63139180A (ja) * 1986-12-02 1988-06-10 Tanabe Seiyaku Co Ltd カルボン酸誘導体

Also Published As

Publication number Publication date
EP0231139A2 (fr) 1987-08-05
IT1205729B (it) 1989-03-31
DE3702005A1 (de) 1987-08-06
FI870347A7 (fi) 1987-07-31
BG46600A3 (en) 1990-01-15
KR870007160A (ko) 1987-08-17
NO168582B (no) 1991-12-02
GB2187188A (en) 1987-09-03
IL81299A0 (en) 1987-08-31
CA1300161C (fr) 1992-05-05
NO870199D0 (no) 1987-01-16
FR2593504A1 (fr) 1987-07-31
CN1016420B (zh) 1992-04-29
CH670827A5 (en.html) 1989-07-14
PL152491B1 (en) 1990-12-31
TNSN87012A1 (fr) 1990-01-01
GB2187188B (en) 1989-11-08
PT84224B (pt) 1989-03-30
NO168582C (no) 1992-03-11
US5006570A (en) 1991-04-09
PL272298A1 (en) 1989-02-20
DE3774888D1 (de) 1992-01-16
IN164389B (en.html) 1989-03-04
ES2038679T3 (es) 1993-08-01
ZA87552B (en) 1987-10-28
IL81299A (en) 1991-09-16
IE870128L (en) 1987-07-30
ES2003671A6 (es) 1988-11-01
CS264288B2 (en) 1989-06-13
EP0231139A3 (en) 1988-04-27
DK46987D0 (da) 1987-01-29
EP0231139B1 (fr) 1991-12-04
PL263885A1 (en) 1988-09-15
YU11387A (en) 1988-06-30
SU1607688A3 (ru) 1990-11-15
DD260065A5 (de) 1988-09-14
ZW1387A1 (en) 1987-10-28
IS3189A7 (is) 1987-07-31
PT84224A (fr) 1987-02-01
GB8701870D0 (en) 1987-03-04
LU86747A1 (fr) 1987-06-02
FI870347A0 (fi) 1987-01-27
SU1609451A3 (ru) 1990-11-23
CS36288A2 (en) 1988-09-16
HUT47093A (en) 1989-01-30
OA08472A (fr) 1988-07-29
CS57887A2 (en) 1988-09-16
JPS62277376A (ja) 1987-12-02
CN87100978A (zh) 1987-09-16
PH23392A (en) 1989-07-26
CS264300B2 (cs) 1989-06-13
AU6785587A (en) 1987-08-06
HU206107B (en) 1992-08-28
YU46185B (sh) 1993-05-28
ATE70063T1 (de) 1991-12-15
ZM987A1 (en) 1987-09-30
CN1062144A (zh) 1992-06-24
GR3003653T3 (en.html) 1993-03-16
FR2593504B1 (fr) 1988-12-09
IN167060B (en.html) 1990-08-25
NO870199L (no) 1987-07-31
AU593605B2 (en) 1990-02-15
MA20861A1 (fr) 1987-10-01
IT8747583A0 (it) 1987-01-29
GR870134B (en) 1987-05-28
BE1000164A5 (fr) 1988-07-05
PL152404B1 (en) 1990-12-31
DK46987A (da) 1987-07-31
IS1446B6 (is) 1990-12-14

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