KR870007160A - 신규의 디하이드로벤조푸란-및 크로만-카복스아미드 유도체, 그것의 제조 방법 및 신경이완제로서의 사용법 - Google Patents

신규의 디하이드로벤조푸란-및 크로만-카복스아미드 유도체, 그것의 제조 방법 및 신경이완제로서의 사용법 Download PDF

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Publication number
KR870007160A
KR870007160A KR870000673A KR870000673A KR870007160A KR 870007160 A KR870007160 A KR 870007160A KR 870000673 A KR870000673 A KR 870000673A KR 870000673 A KR870000673 A KR 870000673A KR 870007160 A KR870007160 A KR 870007160A
Authority
KR
South Korea
Prior art keywords
formula
group
pyrrolidinylmethyl
methyl
carboxamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR870000673A
Other languages
English (en)
Korean (ko)
Inventor
프랑세시니 잭클린
마가릿트 조셋
Original Assignee
라보라토리스 델라그랑그
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 라보라토리스 델라그랑그 filed Critical 라보라토리스 델라그랑그
Publication of KR870007160A publication Critical patent/KR870007160A/ko
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
  • Furan Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polyamides (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR870000673A 1986-01-30 1987-01-28 신규의 디하이드로벤조푸란-및 크로만-카복스아미드 유도체, 그것의 제조 방법 및 신경이완제로서의 사용법 Ceased KR870007160A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR01279 1986-01-30
FR8601279A FR2593504B1 (fr) 1986-01-30 1986-01-30 Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques

Publications (1)

Publication Number Publication Date
KR870007160A true KR870007160A (ko) 1987-08-17

Family

ID=9331629

Family Applications (1)

Application Number Title Priority Date Filing Date
KR870000673A Ceased KR870007160A (ko) 1986-01-30 1987-01-28 신규의 디하이드로벤조푸란-및 크로만-카복스아미드 유도체, 그것의 제조 방법 및 신경이완제로서의 사용법

Country Status (40)

Country Link
US (1) US5006570A (en.html)
EP (1) EP0231139B1 (en.html)
JP (1) JPS62277376A (en.html)
KR (1) KR870007160A (en.html)
CN (2) CN1016420B (en.html)
AT (1) ATE70063T1 (en.html)
AU (1) AU593605B2 (en.html)
BE (1) BE1000164A5 (en.html)
BG (1) BG46600A3 (en.html)
CA (1) CA1300161C (en.html)
CH (1) CH670827A5 (en.html)
CS (2) CS264288B2 (en.html)
DD (1) DD260065A5 (en.html)
DE (2) DE3702005A1 (en.html)
DK (1) DK46987A (en.html)
ES (2) ES2003671A6 (en.html)
FI (1) FI870347A7 (en.html)
FR (1) FR2593504B1 (en.html)
GB (1) GB2187188B (en.html)
GR (2) GR870134B (en.html)
HU (1) HU206107B (en.html)
IE (1) IE870128L (en.html)
IL (1) IL81299A (en.html)
IN (2) IN164389B (en.html)
IS (1) IS1446B6 (en.html)
IT (1) IT1205729B (en.html)
LU (1) LU86747A1 (en.html)
MA (1) MA20861A1 (en.html)
NO (1) NO168582C (en.html)
NZ (1) NZ219068A (en.html)
OA (1) OA08472A (en.html)
PH (1) PH23392A (en.html)
PL (2) PL152404B1 (en.html)
PT (1) PT84224B (en.html)
SU (2) SU1609451A3 (en.html)
TN (1) TNSN87012A1 (en.html)
YU (1) YU46185B (en.html)
ZA (1) ZA87552B (en.html)
ZM (1) ZM987A1 (en.html)
ZW (1) ZW1387A1 (en.html)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2611715B1 (fr) * 1987-02-27 1989-05-12 Adir Nouveaux acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2611713B1 (fr) * 1987-02-27 1990-11-30 Adir Nouveaux derives de l'acide (dihydro-2,3 oxo-2 benzofurannyl-3)-2 acetique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
US5374637A (en) * 1989-03-22 1994-12-20 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives
JP2726306B2 (ja) * 1989-04-14 1998-03-11 本田技研工業株式会社 車両の前後輪操舵装置
US5122361A (en) * 1989-04-17 1992-06-16 Trustees Of The University Of Pennsylvania Dopamine receptor ligands and imaging agents
EP0412939A3 (en) * 1989-08-11 1991-09-04 Ciba-Geigy Ag Certain benzopyran and benzothiopyran derivatives
US5420151A (en) * 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
US5616610A (en) * 1989-12-22 1997-04-01 Astra Aktiebolag (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans
GB9005014D0 (en) 1990-03-06 1990-05-02 Janssen Pharmaceutica Nv N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives
WO1991017144A1 (en) * 1990-05-02 1991-11-14 Yoshitomi Pharmaceutical Industries, Ltd. Amide compound, pharmaceutical use thereof and novel 1-substituted pyrrolidinemethyl-amines
US5114947A (en) * 1990-12-27 1992-05-19 Erbamont Inc. Method for alleviating anxiety using benzobicyclic carboxamides
MA22647A1 (fr) * 1991-09-14 1993-04-01 Smithkline Beecham Plc Procede de preparation d'un ester ou d'un amide d'un nouveau produit .
NZ246915A (en) * 1992-02-06 1996-05-28 Smithkline Beecham Plc Benzopyran, benzothiopyran and benzofuran derivatives, preparation and pharmaceutical compositions thereof
WO1994008994A1 (en) * 1992-10-13 1994-04-28 Smithkline Beecham Plc Heterocyclic -esters or -amides used as 5-ht4 receptor antagonists
US6127379A (en) * 1993-02-01 2000-10-03 Smithkline Beecham P.L.C. Benzopyran, benzothiopyran and benzofuran derivatives as 5-HT4 antagonists
RU2129556C1 (ru) * 1993-08-19 1999-04-27 Жансен Фармасетика Н.В. Производное дигидробензопирана, обладающее сосудосуживающим действием, промежуточные соединения, способы получения, фармацевтическая композиция и способ ее получения
JP2999669B2 (ja) * 1993-08-24 2000-01-17 株式会社三和化学研究所 ベンゾ［ｂ］フランカルボキサミド誘導体、その製法及び用途
JPH0820586A (ja) * 1994-07-05 1996-01-23 Sanwa Kagaku Kenkyusho Co Ltd １−アザビシクロ［３．３．０］オクタン誘導体、その塩及び製法並びに用途
JPH0873463A (ja) 1994-07-05 1996-03-19 Sanwa Kagaku Kenkyusho Co Ltd ベンゾピランカルボキサミド誘導体、その塩及び製法並びに用途
TW490465B (en) * 1994-11-24 2002-06-11 Janssen Pharmaceutica Nv Enterokinetic benzamide, the preparation process and the pharmaceutical compositions thereof
TW475930B (en) * 1995-04-24 2002-02-11 Novartis Ag Novel compound, its use and pharmaceutical composition comprising it

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0135545A1 (en) * 1983-02-19 1985-04-03 Beecham Group Plc Azabicycloalkyl benzamide and anilide derivatives
JPS59186969A (ja) * 1983-04-08 1984-10-23 Yoshitomi Pharmaceut Ind Ltd ベンゾフラン−およびベンゾピランカルボキサミド誘導体
CA1297877C (en) * 1983-12-22 1992-03-24 Daniel Lednicer Benzofurancarboxamides useful as antiemetic or antipsychotic agents
JPS63139180A (ja) * 1986-12-02 1988-06-10 Tanabe Seiyaku Co Ltd カルボン酸誘導体

Also Published As

Publication number Publication date
EP0231139A2 (fr) 1987-08-05
IT1205729B (it) 1989-03-31
DE3702005A1 (de) 1987-08-06
FI870347A7 (fi) 1987-07-31
BG46600A3 (en) 1990-01-15
NO168582B (no) 1991-12-02
GB2187188A (en) 1987-09-03
IL81299A0 (en) 1987-08-31
CA1300161C (fr) 1992-05-05
NO870199D0 (no) 1987-01-16
FR2593504A1 (fr) 1987-07-31
CN1016420B (zh) 1992-04-29
CH670827A5 (en.html) 1989-07-14
PL152491B1 (en) 1990-12-31
TNSN87012A1 (fr) 1990-01-01
GB2187188B (en) 1989-11-08
PT84224B (pt) 1989-03-30
NO168582C (no) 1992-03-11
US5006570A (en) 1991-04-09
PL272298A1 (en) 1989-02-20
DE3774888D1 (de) 1992-01-16
IN164389B (en.html) 1989-03-04
ES2038679T3 (es) 1993-08-01
ZA87552B (en) 1987-10-28
IL81299A (en) 1991-09-16
IE870128L (en) 1987-07-30
ES2003671A6 (es) 1988-11-01
CS264288B2 (en) 1989-06-13
EP0231139A3 (en) 1988-04-27
DK46987D0 (da) 1987-01-29
EP0231139B1 (fr) 1991-12-04
PL263885A1 (en) 1988-09-15
YU11387A (en) 1988-06-30
SU1607688A3 (ru) 1990-11-15
DD260065A5 (de) 1988-09-14
ZW1387A1 (en) 1987-10-28
IS3189A7 (is) 1987-07-31
PT84224A (fr) 1987-02-01
GB8701870D0 (en) 1987-03-04
LU86747A1 (fr) 1987-06-02
FI870347A0 (fi) 1987-01-27
SU1609451A3 (ru) 1990-11-23
CS36288A2 (en) 1988-09-16
NZ219068A (en) 1990-12-21
HUT47093A (en) 1989-01-30
OA08472A (fr) 1988-07-29
CS57887A2 (en) 1988-09-16
JPS62277376A (ja) 1987-12-02
CN87100978A (zh) 1987-09-16
PH23392A (en) 1989-07-26
CS264300B2 (cs) 1989-06-13
AU6785587A (en) 1987-08-06
HU206107B (en) 1992-08-28
YU46185B (sh) 1993-05-28
ATE70063T1 (de) 1991-12-15
ZM987A1 (en) 1987-09-30
CN1062144A (zh) 1992-06-24
GR3003653T3 (en.html) 1993-03-16
FR2593504B1 (fr) 1988-12-09
IN167060B (en.html) 1990-08-25
NO870199L (no) 1987-07-31
AU593605B2 (en) 1990-02-15
MA20861A1 (fr) 1987-10-01
IT8747583A0 (it) 1987-01-29
GR870134B (en) 1987-05-28
BE1000164A5 (fr) 1988-07-05
PL152404B1 (en) 1990-12-31
DK46987A (da) 1987-07-31
IS1446B6 (is) 1990-12-14

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