NO331734B1 - Anvendelse av et syklopeptid til fremstilling av et medikament for bekjempelse av tumorer ved stralebehandling. - Google Patents
Anvendelse av et syklopeptid til fremstilling av et medikament for bekjempelse av tumorer ved stralebehandling. Download PDFInfo
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- NO331734B1 NO331734B1 NO20011308A NO20011308A NO331734B1 NO 331734 B1 NO331734 B1 NO 331734B1 NO 20011308 A NO20011308 A NO 20011308A NO 20011308 A NO20011308 A NO 20011308A NO 331734 B1 NO331734 B1 NO 331734B1
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- Prior art keywords
- acid
- acceptable salts
- physiologically acceptable
- nme
- cyclo
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Ophthalmology & Optometry (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19842415A DE19842415A1 (de) | 1998-09-16 | 1998-09-16 | Pharmazeutische Zubereitung |
| PCT/EP1999/006654 WO2000015244A2 (de) | 1998-09-16 | 1999-09-09 | Pharmazeutische zubereitung enthaltend ein cyclo-peptide und ein chemotherapeutikum oder einen angiogeneseinhibitor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20011308D0 NO20011308D0 (no) | 2001-03-15 |
| NO20011308L NO20011308L (no) | 2001-03-15 |
| NO331734B1 true NO331734B1 (no) | 2012-03-12 |
Family
ID=7881169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20011308A NO331734B1 (no) | 1998-09-16 | 2001-03-15 | Anvendelse av et syklopeptid til fremstilling av et medikament for bekjempelse av tumorer ved stralebehandling. |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US6683051B1 (hu) |
| EP (2) | EP1113809B1 (hu) |
| JP (2) | JP2002524526A (hu) |
| KR (1) | KR100703253B1 (hu) |
| CN (2) | CN1201812C (hu) |
| AR (2) | AR022382A1 (hu) |
| AT (2) | ATE432707T1 (hu) |
| AU (1) | AU765073B2 (hu) |
| BR (1) | BR9913737A (hu) |
| CA (1) | CA2344151A1 (hu) |
| CO (1) | CO5140070A1 (hu) |
| CZ (1) | CZ302908B6 (hu) |
| DE (3) | DE19842415A1 (hu) |
| DK (2) | DK1466615T3 (hu) |
| ES (2) | ES2327331T3 (hu) |
| HU (1) | HUP0103521A3 (hu) |
| ID (1) | ID29226A (hu) |
| IL (2) | IL141516A0 (hu) |
| MY (1) | MY129572A (hu) |
| NO (1) | NO331734B1 (hu) |
| NZ (1) | NZ510040A (hu) |
| PE (1) | PE20001046A1 (hu) |
| PL (1) | PL201902B1 (hu) |
| PT (2) | PT1466615E (hu) |
| RU (1) | RU2227041C2 (hu) |
| SI (1) | SI1113809T1 (hu) |
| SK (1) | SK287012B6 (hu) |
| TR (1) | TR200100765T2 (hu) |
| TW (1) | TW576744B (hu) |
| WO (1) | WO2000015244A2 (hu) |
| ZA (1) | ZA200103073B (hu) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7740841B1 (en) * | 2000-01-28 | 2010-06-22 | Sunnybrook Health Science Center | Therapeutic method for reducing angiogenesis |
| PL206142B1 (pl) * | 2001-01-09 | 2010-07-30 | Merck Patent Gmbhmerck Patent Gmbh | Kompozycja i zestaw farmaceutyczny do leczenia nowotworów i przerzutów nowotworowych oraz ich zastosowanie |
| WO2003074045A1 (fr) * | 2002-03-05 | 2003-09-12 | Eisai Co., Ltd. | Agent antitumoral comprenant une combinaison d'un compose heterocyclique contenant un sulfamide et d'un inhibiteur d'angiogenese |
| CN1964740A (zh) | 2004-04-02 | 2007-05-16 | 加利福尼亚大学董事会 | 治疗和预防与αVβ5整联蛋白有关的疾病的方法和组合物 |
| US9399662B2 (en) * | 2005-11-02 | 2016-07-26 | Duke University | Concurrent chemotherapy and immunotherapy |
| EP1973569B1 (en) * | 2006-01-18 | 2013-05-22 | Merck Patent GmbH | Specific therapy using integrin ligands for treating cancer |
| US20110165150A1 (en) * | 2006-01-18 | 2011-07-07 | Merck Patent Gmbh | Isolated organ perfusion combination therapy of cancer |
| PL2101805T3 (pl) | 2007-01-18 | 2013-04-30 | Merck Patent Gmbh | Ligandy integryn do stosowania w leczeniu nowotworów |
| EP2526967A1 (en) | 2007-07-17 | 2012-11-28 | Merck Patent GmbH | Engineered anti-alpha v-integrin hybrid antibodies |
| WO2010051667A1 (zh) * | 2008-11-10 | 2010-05-14 | 复旦大学 | 一种环肽纳米管药物组合物及其应用 |
| WO2010057596A2 (en) * | 2008-11-20 | 2010-05-27 | Merck Patent Gmbh | New therapy and medicament using integrin ligands for treating cancer |
| WO2010136168A2 (en) | 2009-05-25 | 2010-12-02 | Merck Patent Gmbh | Continuous administration of integrin ligands for treating cancer |
| BR112012001463A2 (pt) | 2009-07-24 | 2016-03-15 | Univ California | métodos e composições para tratar e prevenir doença associada à integrina alfavbeta5 |
| MX2012006450A (es) | 2009-12-10 | 2012-06-28 | Merck Patent Gmbh | Composicion farmaceutica que comprende oligopeptidos. |
| CN103153328A (zh) | 2010-07-16 | 2013-06-12 | 默克专利股份有限公司 | 肽在乳腺癌和/或骨转移灶的治疗中的用途 |
| WO2012069149A1 (en) | 2010-11-23 | 2012-05-31 | Merck Patent Gmbh | Solution comprising cyclic oligopeptides |
| JP6320042B2 (ja) | 2011-02-11 | 2018-05-09 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | 前立腺癌治療のための抗アルファ−ｖインテグリン抗体 |
| WO2012110200A1 (en) * | 2011-02-18 | 2012-08-23 | Merck Patent Gmbh | Cyclic peptide cyclo (l -arginyl - glycyl - l -aspartyl - d - phenylalanyl - n-methyl - l -valyl), compositions thereof, and use thereof in methods for treating graft -versus - host disease |
| US10478501B2 (en) * | 2011-06-09 | 2019-11-19 | Merck Patent Gmbh | Method of treating disorders using a pharmaceutical composition of oligopeptides |
| WO2013130775A1 (en) * | 2012-03-01 | 2013-09-06 | Dizerega, Gere, S. | Methods for treating patients undergoing multi-cycle chemotherapy |
| CN103333227B (zh) * | 2013-06-07 | 2015-10-07 | 东南大学 | 转移肿瘤缺失蛋白小分子环肽抑制剂及其制备方法与应用 |
| EP3510407A1 (en) | 2016-09-08 | 2019-07-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for diagnosing and treating nephrotic syndrome |
| JP2019208422A (ja) * | 2018-06-04 | 2019-12-12 | コリア・インスティテュート・オブ・サイエンス・アンド・テクノロジー | ヒアルロニダーゼを含む新規な組換えエキソソーム及びその用途 |
| GB201911816D0 (en) * | 2019-08-16 | 2019-10-02 | Univ London Queen Mary | Treatment |
| GB202103122D0 (en) * | 2021-03-05 | 2021-04-21 | Univ London Queen Mary | Treatment |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04367367A (ja) | 1991-06-11 | 1992-12-18 | Nkk Corp | ロータリノズル |
| WO1994008577A1 (en) | 1992-10-14 | 1994-04-28 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| CA2150550A1 (en) | 1992-12-01 | 1994-06-09 | Melissa S. Egbertson | Fibrinogen receptor antagonists |
| US5741796A (en) | 1994-05-27 | 1998-04-21 | Merck & Co., Inc. | Pyridyl and naphthyridyl compounds for inhibiting osteoclast-mediated bone resorption |
| JPH10504807A (ja) | 1994-06-29 | 1998-05-12 | スミスクライン・ビーチャム・コーポレイション | ビトロネクチン受容体拮抗剤 |
| JPH10504808A (ja) | 1994-06-29 | 1998-05-12 | スミスクライン・ビーチャム・コーポレイション | ビトロネクチン受容体拮抗物質 |
| DK0710657T3 (da) | 1994-11-02 | 1999-05-25 | Merck Patent Gmbh | Adhæsionsreceptor-antagonister |
| DE19534177A1 (de) * | 1995-09-15 | 1997-03-20 | Merck Patent Gmbh | Cyclische Adhäsionsinhibitoren |
| DE19548709A1 (de) * | 1995-12-23 | 1997-07-03 | Merck Patent Gmbh | Tyrosinderivate |
| JPH09208571A (ja) * | 1996-02-02 | 1997-08-12 | Takeda Chem Ind Ltd | アルキリデンシクロヘキサン誘導体 |
| AU2438297A (en) * | 1996-05-09 | 1997-11-26 | Alcon Laboratories, Inc. | Combinations of angiostatic compounds |
| US5919815A (en) * | 1996-05-22 | 1999-07-06 | Neuromedica, Inc. | Taxane compounds and compositions |
| JP2002515036A (ja) * | 1996-05-31 | 2002-05-21 | ザ スクリップス リサーチ インスティテュート | α▲下Ｖ▼β▲下５▼媒介血管形成の抑制に有用な方法および組成物 |
| JPH1081631A (ja) * | 1996-07-17 | 1998-03-31 | Takeda Chem Ind Ltd | 癌転移または再発抑制剤 |
| DE19629817A1 (de) | 1996-07-24 | 1998-01-29 | Hoechst Ag | Neue Imino-Derivate als Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten |
| DE19629816A1 (de) | 1996-07-24 | 1998-01-29 | Hoechst Ag | Neue Cycloalkyl-Derivate als Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten |
| UA60311C2 (uk) * | 1996-10-02 | 2003-10-15 | Смітклайн Бічам Корпорейшн | Антагоністи рецептора вітронектину, спосіб одержання цих сполук та фармацевтична композиція |
| AU729869B2 (en) | 1997-01-17 | 2001-02-15 | Merck & Co., Inc. | Integrin antagonists |
| DE19850131A1 (de) | 1998-10-30 | 2000-05-04 | Merck Patent Gmbh | Chromenon- und Chromanonderivate |
-
1998
- 1998-09-16 DE DE19842415A patent/DE19842415A1/de not_active Withdrawn
-
1999
- 1999-09-09 DK DK04006076T patent/DK1466615T3/da active
- 1999-09-09 SK SK337-2001A patent/SK287012B6/sk not_active IP Right Cessation
- 1999-09-09 HU HU0103521A patent/HUP0103521A3/hu unknown
- 1999-09-09 CZ CZ20010932A patent/CZ302908B6/cs not_active IP Right Cessation
- 1999-09-09 BR BR9913737-2A patent/BR9913737A/pt not_active Application Discontinuation
- 1999-09-09 PT PT04006076T patent/PT1466615E/pt unknown
- 1999-09-09 AT AT04006076T patent/ATE432707T1/de active
- 1999-09-09 WO PCT/EP1999/006654 patent/WO2000015244A2/de active IP Right Grant
- 1999-09-09 AT AT99969031T patent/ATE292470T1/de active
- 1999-09-09 TR TR2001/00765T patent/TR200100765T2/xx unknown
- 1999-09-09 US US09/787,374 patent/US6683051B1/en not_active Expired - Lifetime
- 1999-09-09 EP EP99969031A patent/EP1113809B1/de not_active Expired - Lifetime
- 1999-09-09 RU RU2001110104/15A patent/RU2227041C2/ru not_active IP Right Cessation
- 1999-09-09 CA CA002344151A patent/CA2344151A1/en not_active Abandoned
- 1999-09-09 ID IDW20010746A patent/ID29226A/id unknown
- 1999-09-09 IL IL14151699A patent/IL141516A0/xx unknown
- 1999-09-09 DK DK99969031T patent/DK1113809T3/da active
- 1999-09-09 PL PL348026A patent/PL201902B1/pl not_active IP Right Cessation
- 1999-09-09 EP EP04006076A patent/EP1466615B1/de not_active Expired - Lifetime
- 1999-09-09 ES ES04006076T patent/ES2327331T3/es not_active Expired - Lifetime
- 1999-09-09 CN CNB998133876A patent/CN1201812C/zh not_active Expired - Fee Related
- 1999-09-09 DE DE59915033T patent/DE59915033D1/de not_active Expired - Lifetime
- 1999-09-09 PT PT99969031T patent/PT1113809E/pt unknown
- 1999-09-09 SI SI9930792T patent/SI1113809T1/xx unknown
- 1999-09-09 DE DE59911881T patent/DE59911881D1/de not_active Expired - Lifetime
- 1999-09-09 CN CNB2004100834955A patent/CN100352494C/zh not_active Expired - Fee Related
- 1999-09-09 NZ NZ510040A patent/NZ510040A/en not_active IP Right Cessation
- 1999-09-09 AU AU59758/99A patent/AU765073B2/en not_active Ceased
- 1999-09-09 JP JP2000569828A patent/JP2002524526A/ja active Pending
- 1999-09-09 KR KR1020017003238A patent/KR100703253B1/ko not_active IP Right Cessation
- 1999-09-09 ES ES99969031T patent/ES2241363T3/es not_active Expired - Lifetime
- 1999-09-13 MY MYPI99003955A patent/MY129572A/en unknown
- 1999-09-13 PE PE1999000926A patent/PE20001046A1/es not_active Application Discontinuation
- 1999-09-15 AR ARP990104617A patent/AR022382A1/es not_active Application Discontinuation
- 1999-09-16 TW TW088116003A patent/TW576744B/zh not_active IP Right Cessation
- 1999-09-16 CO CO99058733A patent/CO5140070A1/es unknown
-
2001
- 2001-02-19 IL IL141516A patent/IL141516A/en not_active IP Right Cessation
- 2001-03-15 NO NO20011308A patent/NO331734B1/no not_active IP Right Cessation
- 2001-04-12 ZA ZA200103073A patent/ZA200103073B/en unknown
-
2010
- 2010-09-15 AR ARP100103356A patent/AR078175A2/es not_active Application Discontinuation
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2011
- 2011-08-12 JP JP2011176480A patent/JP2011252012A/ja active Pending
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