CO5140070A1 - Composicion farmaceutica -fen-nme-val) y compuesto quimioterapeutico para combatir las enfermedades angiogenicas patologicas, la trombosis, el infarto del miocardio, las enfermedades coronarias, la arte- riosclerosis, los tumores, la osteoporosis,las - Google Patents

Composicion farmaceutica -fen-nme-val) y compuesto quimioterapeutico para combatir las enfermedades angiogenicas patologicas, la trombosis, el infarto del miocardio, las enfermedades coronarias, la arte- riosclerosis, los tumores, la osteoporosis,las

Info

Publication number
CO5140070A1
CO5140070A1 CO99058733A CO99058733A CO5140070A1 CO 5140070 A1 CO5140070 A1 CO 5140070A1 CO 99058733 A CO99058733 A CO 99058733A CO 99058733 A CO99058733 A CO 99058733A CO 5140070 A1 CO5140070 A1 CO 5140070A1
Authority
CO
Colombia
Prior art keywords
diseases
nme
fen
val
thermophoses
Prior art date
Application number
CO99058733A
Other languages
English (en)
Inventor
Alfred Jonczyk
Astrik Perschl
Simon Goodman
Sigrid Rosener
Jutta Haunschild
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of CO5140070A1 publication Critical patent/CO5140070A1/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Un conjunto de piezas (set) que se compone de envases separados de (a) una cantidad efectiva de ciclo-(Arg-Gli-Asp-D-Fen-NMe-Val) y (b) una cantidad efectiva de gemcitabina.
CO99058733A 1998-09-16 1999-09-16 Composicion farmaceutica -fen-nme-val) y compuesto quimioterapeutico para combatir las enfermedades angiogenicas patologicas, la trombosis, el infarto del miocardio, las enfermedades coronarias, la arte- riosclerosis, los tumores, la osteoporosis,las CO5140070A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19842415A DE19842415A1 (de) 1998-09-16 1998-09-16 Pharmazeutische Zubereitung

Publications (1)

Publication Number Publication Date
CO5140070A1 true CO5140070A1 (es) 2002-03-22

Family

ID=7881169

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99058733A CO5140070A1 (es) 1998-09-16 1999-09-16 Composicion farmaceutica -fen-nme-val) y compuesto quimioterapeutico para combatir las enfermedades angiogenicas patologicas, la trombosis, el infarto del miocardio, las enfermedades coronarias, la arte- riosclerosis, los tumores, la osteoporosis,las

Country Status (31)

Country Link
US (1) US6683051B1 (es)
EP (2) EP1113809B1 (es)
JP (2) JP2002524526A (es)
KR (1) KR100703253B1 (es)
CN (2) CN1201812C (es)
AR (2) AR022382A1 (es)
AT (2) ATE292470T1 (es)
AU (1) AU765073B2 (es)
BR (1) BR9913737A (es)
CA (1) CA2344151A1 (es)
CO (1) CO5140070A1 (es)
CZ (1) CZ302908B6 (es)
DE (3) DE19842415A1 (es)
DK (2) DK1466615T3 (es)
ES (2) ES2327331T3 (es)
HU (1) HUP0103521A3 (es)
ID (1) ID29226A (es)
IL (2) IL141516A0 (es)
MY (1) MY129572A (es)
NO (1) NO331734B1 (es)
NZ (1) NZ510040A (es)
PE (1) PE20001046A1 (es)
PL (1) PL201902B1 (es)
PT (2) PT1466615E (es)
RU (1) RU2227041C2 (es)
SI (1) SI1113809T1 (es)
SK (1) SK287012B6 (es)
TR (1) TR200100765T2 (es)
TW (1) TW576744B (es)
WO (1) WO2000015244A2 (es)
ZA (1) ZA200103073B (es)

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BRPI0815567B8 (pt) 2007-07-17 2021-05-25 Merck Patent Gessellschaft Mit Beschraenkter Haftung anticorpos híbridos anti-alfa v-integrina projetados, proteína de fusão e composição farmacêutica
US20100069302A1 (en) 2007-07-18 2010-03-18 Stefan Krueger Specific therapy and medicament using integrin ligands for treating cancer
WO2010051667A1 (zh) * 2008-11-10 2010-05-14 复旦大学 一种环肽纳米管药物组合物及其应用
MX2011005256A (es) * 2008-11-20 2011-05-31 Merck Patent Gmbh Nueva terapia y medicamento que usa liganodos de integrina para tratamiento de cancer.
JP2012528079A (ja) 2009-05-25 2012-11-12 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 癌を治療するためのインテグリンリガンドの連続投与
KR101752515B1 (ko) 2009-07-24 2017-06-29 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 Ａｖｂ５ 인테그린과 결부된 질환의 치료 및 예방을 위한 방법 및 조성물
PE20121359A1 (es) 2009-12-10 2012-10-15 Merck Patent Gmbh Composicion farmaceutica que comprende oligopeptidos
CA2805338A1 (en) 2010-07-16 2012-01-19 Merck Patent Gmbh Peptide for use in the treatment of breast cancer and/or bone metastases
WO2012069149A1 (en) 2010-11-23 2012-05-31 Merck Patent Gmbh Solution comprising cyclic oligopeptides
JP6320042B2 (ja) 2011-02-11 2018-05-09 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ 前立腺癌治療のための抗アルファ−ｖインテグリン抗体
WO2012110200A1 (en) * 2011-02-18 2012-08-23 Merck Patent Gmbh Cyclic peptide cyclo (l -arginyl - glycyl - l -aspartyl - d - phenylalanyl - n-methyl - l -valyl), compositions thereof, and use thereof in methods for treating graft -versus - host disease
ES2720477T3 (es) 2011-06-09 2019-07-22 Merck Patent Gmbh Tratamiento de cánceres y metástasis con suspensiones de Cilengitide en portador
WO2013130775A1 (en) * 2012-03-01 2013-09-06 Dizerega, Gere, S. Methods for treating patients undergoing multi-cycle chemotherapy
CN103333227B (zh) * 2013-06-07 2015-10-07 东南大学 转移肿瘤缺失蛋白小分子环肽抑制剂及其制备方法与应用
US20190242908A1 (en) 2016-09-08 2019-08-08 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for diagnosing and treating nephrotic syndrome
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Also Published As

Publication number Publication date
PT1466615E (pt) 2009-09-07
RU2227041C2 (ru) 2004-04-20
NO331734B1 (no) 2012-03-12
ATE292470T1 (de) 2005-04-15
CN100352494C (zh) 2007-12-05
ES2241363T3 (es) 2005-10-16
EP1113809A2 (de) 2001-07-11
MY129572A (en) 2007-04-30
CN1636590A (zh) 2005-07-13
IL141516A (en) 2009-09-22
TW576744B (en) 2004-02-21
JP2011252012A (ja) 2011-12-15
PL348026A1 (en) 2002-05-06
EP1113809B1 (de) 2005-04-06
PL201902B1 (pl) 2009-05-29
CZ2001932A3 (cs) 2001-09-12
AU765073B2 (en) 2003-09-11
NO20011308D0 (no) 2001-03-15
WO2000015244A2 (de) 2000-03-23
AR022382A1 (es) 2002-09-04
CA2344151A1 (en) 2000-03-23
AU5975899A (en) 2000-04-03
CN1201812C (zh) 2005-05-18
WO2000015244A3 (de) 2000-06-22
ZA200103073B (en) 2002-08-21
SK3372001A3 (en) 2001-11-06
ATE432707T1 (de) 2009-06-15
IL141516A0 (en) 2002-03-10
KR100703253B1 (ko) 2007-04-03
DE59911881D1 (de) 2005-05-12
DK1466615T3 (da) 2009-08-31
CZ302908B6 (cs) 2012-01-18
DE59915033D1 (de) 2009-07-16
EP1466615B1 (de) 2009-06-03
AR078175A2 (es) 2011-10-19
CN1329499A (zh) 2002-01-02
DK1113809T3 (da) 2005-08-08
PT1113809E (pt) 2005-08-31
ES2327331T3 (es) 2009-10-28
TR200100765T2 (tr) 2001-08-21
HUP0103521A3 (en) 2002-05-28
NZ510040A (en) 2003-12-19
PE20001046A1 (es) 2000-10-14
NO20011308L (no) 2001-03-15
SI1113809T1 (en) 2005-10-31
ID29226A (id) 2001-08-16
SK287012B6 (sk) 2009-09-07
HUP0103521A2 (hu) 2002-02-28
EP1466615A1 (de) 2004-10-13
KR20010073155A (ko) 2001-07-31
DE19842415A1 (de) 2000-03-23
US6683051B1 (en) 2004-01-27
JP2002524526A (ja) 2002-08-06
BR9913737A (pt) 2001-06-05

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