ZA200103073B - Pharmaceutical preparation containing a cyclopeptide and a chemotherapeutic agent or an angiogenesis inhibitor. - Google Patents
Pharmaceutical preparation containing a cyclopeptide and a chemotherapeutic agent or an angiogenesis inhibitor. Download PDFInfo
- Publication number
- ZA200103073B ZA200103073B ZA200103073A ZA200103073A ZA200103073B ZA 200103073 B ZA200103073 B ZA 200103073B ZA 200103073 A ZA200103073 A ZA 200103073A ZA 200103073 A ZA200103073 A ZA 200103073A ZA 200103073 B ZA200103073 B ZA 200103073B
- Authority
- ZA
- South Africa
- Prior art keywords
- acceptable salts
- physiologically acceptable
- cyclo
- nme
- phe
- Prior art date
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| DE19842415A DE19842415A1 (de) | 1998-09-16 | 1998-09-16 | Pharmazeutische Zubereitung |
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| ZA200103073B true ZA200103073B (en) | 2002-08-21 |
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| ZA200103073A ZA200103073B (en) | 1998-09-16 | 2001-04-12 | Pharmaceutical preparation containing a cyclopeptide and a chemotherapeutic agent or an angiogenesis inhibitor. |
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| EP (2) | EP1113809B1 (es) |
| JP (2) | JP2002524526A (es) |
| KR (1) | KR100703253B1 (es) |
| CN (2) | CN1201812C (es) |
| AR (2) | AR022382A1 (es) |
| AT (2) | ATE292470T1 (es) |
| AU (1) | AU765073B2 (es) |
| BR (1) | BR9913737A (es) |
| CA (1) | CA2344151A1 (es) |
| CO (1) | CO5140070A1 (es) |
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| HU (1) | HUP0103521A3 (es) |
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| IL (2) | IL141516A0 (es) |
| MY (1) | MY129572A (es) |
| NO (1) | NO331734B1 (es) |
| NZ (1) | NZ510040A (es) |
| PE (1) | PE20001046A1 (es) |
| PL (1) | PL201902B1 (es) |
| PT (2) | PT1466615E (es) |
| RU (1) | RU2227041C2 (es) |
| SI (1) | SI1113809T1 (es) |
| SK (1) | SK287012B6 (es) |
| TR (1) | TR200100765T2 (es) |
| TW (1) | TW576744B (es) |
| WO (1) | WO2000015244A2 (es) |
| ZA (1) | ZA200103073B (es) |
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| US7740841B1 (en) * | 2000-01-28 | 2010-06-22 | Sunnybrook Health Science Center | Therapeutic method for reducing angiogenesis |
| BR0116575A (pt) * | 2001-01-09 | 2004-01-06 | Merck Patent Gmbh | Terapia combinada que usa inibidores de tirosina cinase receptora e inibidores de angiogênese |
| WO2003074045A1 (fr) * | 2002-03-05 | 2003-09-12 | Eisai Co., Ltd. | Agent antitumoral comprenant une combinaison d'un compose heterocyclique contenant un sulfamide et d'un inhibiteur d'angiogenese |
| DK1734996T3 (da) * | 2004-04-02 | 2013-06-10 | Univ California | Fremgangsmåder og sammensætninger til behandling og forebyggelse af sygdom, der er associeret med alfa v beta 5-integrin |
| CN103463630A (zh) * | 2005-11-02 | 2013-12-25 | 杜克大学 | 同时的化学疗法和免疫疗法 |
| EP1973569B1 (en) * | 2006-01-18 | 2013-05-22 | Merck Patent GmbH | Specific therapy using integrin ligands for treating cancer |
| US20110165150A1 (en) * | 2006-01-18 | 2011-07-07 | Merck Patent Gmbh | Isolated organ perfusion combination therapy of cancer |
| BRPI0815567B8 (pt) | 2007-07-17 | 2021-05-25 | Merck Patent Gessellschaft Mit Beschraenkter Haftung | anticorpos híbridos anti-alfa v-integrina projetados, proteína de fusão e composição farmacêutica |
| US20100069302A1 (en) | 2007-07-18 | 2010-03-18 | Stefan Krueger | Specific therapy and medicament using integrin ligands for treating cancer |
| WO2010051667A1 (zh) * | 2008-11-10 | 2010-05-14 | 复旦大学 | 一种环肽纳米管药物组合物及其应用 |
| MX2011005256A (es) * | 2008-11-20 | 2011-05-31 | Merck Patent Gmbh | Nueva terapia y medicamento que usa liganodos de integrina para tratamiento de cancer. |
| JP2012528079A (ja) | 2009-05-25 | 2012-11-12 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 癌を治療するためのインテグリンリガンドの連続投与 |
| KR101752515B1 (ko) | 2009-07-24 | 2017-06-29 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | Ａｖｂ５ 인테그린과 결부된 질환의 치료 및 예방을 위한 방법 및 조성물 |
| PE20121359A1 (es) | 2009-12-10 | 2012-10-15 | Merck Patent Gmbh | Composicion farmaceutica que comprende oligopeptidos |
| CA2805338A1 (en) | 2010-07-16 | 2012-01-19 | Merck Patent Gmbh | Peptide for use in the treatment of breast cancer and/or bone metastases |
| WO2012069149A1 (en) | 2010-11-23 | 2012-05-31 | Merck Patent Gmbh | Solution comprising cyclic oligopeptides |
| JP6320042B2 (ja) | 2011-02-11 | 2018-05-09 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | 前立腺癌治療のための抗アルファ−ｖインテグリン抗体 |
| WO2012110200A1 (en) * | 2011-02-18 | 2012-08-23 | Merck Patent Gmbh | Cyclic peptide cyclo (l -arginyl - glycyl - l -aspartyl - d - phenylalanyl - n-methyl - l -valyl), compositions thereof, and use thereof in methods for treating graft -versus - host disease |
| ES2720477T3 (es) | 2011-06-09 | 2019-07-22 | Merck Patent Gmbh | Tratamiento de cánceres y metástasis con suspensiones de Cilengitide en portador |
| WO2013130775A1 (en) * | 2012-03-01 | 2013-09-06 | Dizerega, Gere, S. | Methods for treating patients undergoing multi-cycle chemotherapy |
| CN103333227B (zh) * | 2013-06-07 | 2015-10-07 | 东南大学 | 转移肿瘤缺失蛋白小分子环肽抑制剂及其制备方法与应用 |
| US20190242908A1 (en) | 2016-09-08 | 2019-08-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for diagnosing and treating nephrotic syndrome |
| JP2019208422A (ja) * | 2018-06-04 | 2019-12-12 | コリア・インスティテュート・オブ・サイエンス・アンド・テクノロジー | ヒアルロニダーゼを含む新規な組換えエキソソーム及びその用途 |
| GB201911816D0 (en) * | 2019-08-16 | 2019-10-02 | Univ London Queen Mary | Treatment |
| GB202103122D0 (en) * | 2021-03-05 | 2021-04-21 | Univ London Queen Mary | Treatment |
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| JPH04367367A (ja) | 1991-06-11 | 1992-12-18 | Nkk Corp | ロータリノズル |
| AU674553B2 (en) | 1992-10-14 | 1997-01-02 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| WO1994012181A1 (en) | 1992-12-01 | 1994-06-09 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| AU701776B2 (en) | 1994-05-27 | 1999-02-04 | Merck & Co., Inc. | Compounds for inhibiting osteoclast-mediated bone resorption |
| PL318199A1 (en) | 1994-06-29 | 1997-05-26 | Smithkline Beecham Corp | Antagonists of vitronectin receptors |
| JPH10504807A (ja) | 1994-06-29 | 1998-05-12 | スミスクライン・ビーチャム・コーポレイション | ビトロネクチン受容体拮抗剤 |
| DK0710657T3 (da) | 1994-11-02 | 1999-05-25 | Merck Patent Gmbh | Adhæsionsreceptor-antagonister |
| DE19534177A1 (de) * | 1995-09-15 | 1997-03-20 | Merck Patent Gmbh | Cyclische Adhäsionsinhibitoren |
| DE19548709A1 (de) * | 1995-12-23 | 1997-07-03 | Merck Patent Gmbh | Tyrosinderivate |
| JPH09208571A (ja) * | 1996-02-02 | 1997-08-12 | Takeda Chem Ind Ltd | アルキリデンシクロヘキサン誘導体 |
| WO1997041844A1 (en) * | 1996-05-09 | 1997-11-13 | Alcon Laboratories, Inc. | Combinations of angiostatic compounds |
| US5919815A (en) * | 1996-05-22 | 1999-07-06 | Neuromedica, Inc. | Taxane compounds and compositions |
| PL330241A1 (en) * | 1996-05-31 | 1999-05-10 | Scripps Research Inst | Methods of and compositions useful in inhibiting angiogenesis |
| JPH1081631A (ja) * | 1996-07-17 | 1998-03-31 | Takeda Chem Ind Ltd | 癌転移または再発抑制剤 |
| DE19629816A1 (de) | 1996-07-24 | 1998-01-29 | Hoechst Ag | Neue Cycloalkyl-Derivate als Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten |
| DE19629817A1 (de) | 1996-07-24 | 1998-01-29 | Hoechst Ag | Neue Imino-Derivate als Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten |
| UA60311C2 (uk) * | 1996-10-02 | 2003-10-15 | Смітклайн Бічам Корпорейшн | Антагоністи рецептора вітронектину, спосіб одержання цих сполук та фармацевтична композиція |
| CA2277273C (en) * | 1997-01-17 | 2008-03-25 | Merck & Co., Inc. | Integrin antagonists |
| DE19850131A1 (de) | 1998-10-30 | 2000-05-04 | Merck Patent Gmbh | Chromenon- und Chromanonderivate |
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1998
- 1998-09-16 DE DE19842415A patent/DE19842415A1/de not_active Withdrawn
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1999
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- 1999-09-09 AT AT99969031T patent/ATE292470T1/de active
- 1999-09-09 NZ NZ510040A patent/NZ510040A/en not_active IP Right Cessation
- 1999-09-09 EP EP99969031A patent/EP1113809B1/de not_active Expired - Lifetime
- 1999-09-09 AT AT04006076T patent/ATE432707T1/de active
- 1999-09-09 TR TR2001/00765T patent/TR200100765T2/xx unknown
- 1999-09-09 WO PCT/EP1999/006654 patent/WO2000015244A2/de active IP Right Grant
- 1999-09-09 CA CA002344151A patent/CA2344151A1/en not_active Abandoned
- 1999-09-09 CZ CZ20010932A patent/CZ302908B6/cs not_active IP Right Cessation
- 1999-09-09 CN CNB998133876A patent/CN1201812C/zh not_active Expired - Fee Related
- 1999-09-09 AU AU59758/99A patent/AU765073B2/en not_active Ceased
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- 1999-09-09 DE DE59911881T patent/DE59911881D1/de not_active Expired - Lifetime
- 1999-09-09 SI SI9930792T patent/SI1113809T1/xx unknown
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- 1999-09-09 SK SK337-2001A patent/SK287012B6/sk not_active IP Right Cessation
- 1999-09-09 KR KR1020017003238A patent/KR100703253B1/ko not_active IP Right Cessation
- 1999-09-09 EP EP04006076A patent/EP1466615B1/de not_active Expired - Lifetime
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2001
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2011
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