NO323588B1 - Heterocykliske dihydropyrimidiner som kaliumkanal inhibitorer samt anvendelse derav og farmasoytisk preparat. - Google Patents
Heterocykliske dihydropyrimidiner som kaliumkanal inhibitorer samt anvendelse derav og farmasoytisk preparat. Download PDFInfo
- Publication number
- NO323588B1 NO323588B1 NO20022649A NO20022649A NO323588B1 NO 323588 B1 NO323588 B1 NO 323588B1 NO 20022649 A NO20022649 A NO 20022649A NO 20022649 A NO20022649 A NO 20022649A NO 323588 B1 NO323588 B1 NO 323588B1
- Authority
- NO
- Norway
- Prior art keywords
- ene
- dihydro
- dichlorophenyl
- pyrimidin
- methyl
- Prior art date
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- 125000000623 heterocyclic group Chemical group 0.000 title claims description 27
- 239000003112 inhibitor Substances 0.000 title description 27
- 102000004257 Potassium Channel Human genes 0.000 title description 9
- 108020001213 potassium channel Proteins 0.000 title description 9
- 239000008194 pharmaceutical composition Substances 0.000 title description 4
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- 229940125904 compound 1 Drugs 0.000 claims description 89
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- 125000003118 aryl group Chemical group 0.000 claims description 61
- -1 4-phenyl-1-piperazinyl Chemical group 0.000 claims description 59
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- 125000000217 alkyl group Chemical group 0.000 claims description 55
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- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 17
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- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims description 14
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- 241000009298 Trigla lyra Species 0.000 claims 2
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- 125000004494 ethyl ester group Chemical group 0.000 claims 2
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- POTIYWUALSJREP-UHFFFAOYSA-N 1,2,3,4,4a,5,6,7,8,8a-decahydroquinoline Chemical compound N1CCCC2CCCCC21 POTIYWUALSJREP-UHFFFAOYSA-N 0.000 claims 1
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16909199P | 1999-12-06 | 1999-12-06 | |
| US23603700P | 2000-09-28 | 2000-09-28 | |
| PCT/US2000/032785 WO2001040231A1 (fr) | 1999-12-06 | 2000-12-04 | Dihydropyrimidines heterocycliques utiles en tant qu'inhibiteurs des canaux potassium |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20022649D0 NO20022649D0 (no) | 2002-06-05 |
| NO20022649L NO20022649L (no) | 2002-06-06 |
| NO323588B1 true NO323588B1 (no) | 2007-06-11 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20022649A NO323588B1 (no) | 1999-12-06 | 2002-06-05 | Heterocykliske dihydropyrimidiner som kaliumkanal inhibitorer samt anvendelse derav og farmasoytisk preparat. |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US6706720B2 (fr) |
| EP (1) | EP1237891B1 (fr) |
| JP (1) | JP2004507442A (fr) |
| KR (1) | KR20020060255A (fr) |
| CN (1) | CN1407985A (fr) |
| AR (1) | AR029457A1 (fr) |
| AT (1) | ATE526329T1 (fr) |
| AU (1) | AU781862B2 (fr) |
| BR (1) | BR0016166A (fr) |
| CA (1) | CA2393809C (fr) |
| CO (1) | CO5570109A1 (fr) |
| CZ (1) | CZ20021949A3 (fr) |
| HK (1) | HK1048808A1 (fr) |
| HU (1) | HUP0301834A3 (fr) |
| IL (2) | IL149473A0 (fr) |
| MX (1) | MXPA02005533A (fr) |
| MY (1) | MY125533A (fr) |
| NO (1) | NO323588B1 (fr) |
| NZ (1) | NZ518663A (fr) |
| PE (1) | PE20011029A1 (fr) |
| PL (1) | PL364926A1 (fr) |
| RU (1) | RU2296766C2 (fr) |
| TW (1) | TWI291465B (fr) |
| UY (1) | UY26472A1 (fr) |
| WO (1) | WO2001040231A1 (fr) |
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- 2000-12-04 AU AU18127/01A patent/AU781862B2/en not_active Ceased
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