NO20022649L - Heterocykliske dihydropyrimidiner som kaliumkanal inhibitorer - Google Patents

Heterocykliske dihydropyrimidiner som kaliumkanal inhibitorer

Info

Publication number
NO20022649L
NO20022649L NO20022649A NO20022649A NO20022649L NO 20022649 L NO20022649 L NO 20022649L NO 20022649 A NO20022649 A NO 20022649A NO 20022649 A NO20022649 A NO 20022649A NO 20022649 L NO20022649 L NO 20022649L
Authority
NO
Norway
Prior art keywords
dihydropyrimidines
heterocyclic
potassium channel
channel inhibitors
inhibitors
Prior art date
Application number
NO20022649A
Other languages
English (en)
Other versions
NO20022649D0 (no
NO323588B1 (no
Inventor
Karnail S Atwal
Wayne D Vaccaro
John Lloyd
Heather Finlay
Lin Yan
Rao S Bhandaru
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO20022649D0 publication Critical patent/NO20022649D0/no
Publication of NO20022649L publication Critical patent/NO20022649L/no
Publication of NO323588B1 publication Critical patent/NO323588B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Biotechnology (AREA)
NO20022649A 1999-12-06 2002-06-05 Heterocykliske dihydropyrimidiner som kaliumkanal inhibitorer samt anvendelse derav og farmasoytisk preparat. NO323588B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16909199P 1999-12-06 1999-12-06
US23603700P 2000-09-28 2000-09-28
PCT/US2000/032785 WO2001040231A1 (en) 1999-12-06 2000-12-04 Heterocyclic dihydropyrimidines as potassium channel inhibitors

Publications (3)

Publication Number Publication Date
NO20022649D0 NO20022649D0 (no) 2002-06-05
NO20022649L true NO20022649L (no) 2002-06-06
NO323588B1 NO323588B1 (no) 2007-06-11

Family

ID=26864749

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20022649A NO323588B1 (no) 1999-12-06 2002-06-05 Heterocykliske dihydropyrimidiner som kaliumkanal inhibitorer samt anvendelse derav og farmasoytisk preparat.

Country Status (25)

Country Link
US (3) US6706720B2 (no)
EP (1) EP1237891B1 (no)
JP (1) JP2004507442A (no)
KR (1) KR20020060255A (no)
CN (1) CN1407985A (no)
AR (1) AR029457A1 (no)
AT (1) ATE526329T1 (no)
AU (1) AU781862B2 (no)
BR (1) BR0016166A (no)
CA (1) CA2393809C (no)
CO (1) CO5570109A1 (no)
CZ (1) CZ20021949A3 (no)
HK (1) HK1048808A1 (no)
HU (1) HUP0301834A3 (no)
IL (2) IL149473A0 (no)
MX (1) MXPA02005533A (no)
MY (1) MY125533A (no)
NO (1) NO323588B1 (no)
NZ (1) NZ518663A (no)
PE (1) PE20011029A1 (no)
PL (1) PL364926A1 (no)
RU (1) RU2296766C2 (no)
TW (1) TWI291465B (no)
UY (1) UY26472A1 (no)
WO (1) WO2001040231A1 (no)

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AU7306201A (en) * 2000-06-30 2002-01-14 American Home Prod Substituted-triazolopyrimidines as anticancer agents
EP1350511B1 (en) * 2000-12-25 2008-09-10 Daiichi Sankyo Company, Limited Medicinal compositions containing aspirin
TWI243164B (en) 2001-02-13 2005-11-11 Aventis Pharma Gmbh Acylated indanyl amines and their use as pharmaceuticals
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US20040192673A1 (en) * 2001-05-05 2004-09-30 Pascale Gaillard N-aroyl cyclic amine derivatives as orexin receptor antagonists
US7139344B2 (en) * 2001-05-16 2006-11-21 Lexmark International, Inc. Method and apparatus for effecting synchronous pulse generation for use in variable speed serial communications
CZ20033437A3 (cs) * 2001-06-28 2004-09-15 Smithkline Beecham P.L.C. N-Aroylové cyklické aminové deriváty jako antagonisté orexinového receptoru
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US6833371B2 (en) * 2001-11-01 2004-12-21 Icagen, Inc. Pyrazolopyrimidines
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US6846836B2 (en) 2003-04-18 2005-01-25 Bristol-Myers Squibb Company N-substituted phenylurea inhibitors of mitochondrial F1F0 ATP hydrolase
EP2133348B1 (en) 2003-05-01 2011-08-31 Bristol-Myers Squibb Company Aryl-substituted pyrazole-amide compounds useful as kinase inhibitors
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US20050187278A1 (en) * 2003-08-28 2005-08-25 Pharmacia Corporation Treatment or prevention of vascular disorders with Cox-2 inhibitors in combination with cyclic AMP-specific phosphodiesterase inhibitors
JP4842829B2 (ja) * 2003-10-31 2011-12-21 武田薬品工業株式会社 含窒素縮合複素環化合物
US7550499B2 (en) 2004-05-12 2009-06-23 Bristol-Myers Squibb Company Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
EP1750862B1 (en) * 2004-06-04 2011-01-05 Teva Pharmaceutical Industries Ltd. Pharmaceutical composition containing irbesartan
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US7253167B2 (en) * 2004-06-30 2007-08-07 Bristol-Myers Squibb Company Tricyclic-heteroaryl compounds useful as kinase inhibitors
US7429611B2 (en) * 2004-09-23 2008-09-30 Bristol-Myers Squibb Company Indole inhibitors of 15-lipoxygenase
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US6706720B2 (en) 2004-03-16
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