CA2709187A1 - 4-imidazolidinones comme inhibiteurs du canal potassique kv1.5 - Google Patents

4-imidazolidinones comme inhibiteurs du canal potassique kv1.5 Download PDF

Info

Publication number
CA2709187A1
CA2709187A1 CA2709187A CA2709187A CA2709187A1 CA 2709187 A1 CA2709187 A1 CA 2709187A1 CA 2709187 A CA2709187 A CA 2709187A CA 2709187 A CA2709187 A CA 2709187A CA 2709187 A1 CA2709187 A1 CA 2709187A1
Authority
CA
Canada
Prior art keywords
alkyl
compound
methoxyphenyl
ethyl
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2709187A
Other languages
English (en)
Inventor
Benjamin E. Blass
John M. Janusz
James M. Ridgeway
Shengde Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth Llc
Benjamin E. Blass
John M. Janusz
James M. Ridgeway
Shengde Wu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Llc, Benjamin E. Blass, John M. Janusz, James M. Ridgeway, Shengde Wu filed Critical Wyeth Llc
Publication of CA2709187A1 publication Critical patent/CA2709187A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2709187A 2007-12-19 2008-12-18 4-imidazolidinones comme inhibiteurs du canal potassique kv1.5 Abandoned CA2709187A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1493707P 2007-12-19 2007-12-19
US61/014,937 2007-12-19
PCT/US2008/087459 WO2009079630A1 (fr) 2007-12-19 2008-12-18 4-imidazolidinones comme inhibiteurs du canal potassique kv1.5

Publications (1)

Publication Number Publication Date
CA2709187A1 true CA2709187A1 (fr) 2009-06-25

Family

ID=40379648

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2709187A Abandoned CA2709187A1 (fr) 2007-12-19 2008-12-18 4-imidazolidinones comme inhibiteurs du canal potassique kv1.5

Country Status (8)

Country Link
EP (1) EP2234983A1 (fr)
JP (1) JP2011507887A (fr)
AU (1) AU2008338374A1 (fr)
BR (1) BRPI0821394A2 (fr)
CA (1) CA2709187A1 (fr)
MX (1) MX2010006926A (fr)
WO (1) WO2009079630A1 (fr)
ZA (1) ZA201005086B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO3175985T3 (fr) 2011-07-01 2018-04-28
AU2013203252B2 (en) 2012-01-27 2015-08-20 Gilead Sciences, Inc. Combination therapies using late sodium ion channel blockers and potassium ion channel blockers
WO2014134419A1 (fr) 2013-03-01 2014-09-04 Gilead Sciences, Inc. Utilisation de bloqueurs ikach pour le traitement de maladies cardiaques

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY125533A (en) * 1999-12-06 2006-08-30 Bristol Myers Squibb Co Heterocyclic dihydropyrimidine compounds
JP2009541342A (ja) * 2006-06-20 2009-11-26 ワイス Ｋｖ１．５カリウムチャネル阻害剤

Also Published As

Publication number Publication date
MX2010006926A (es) 2010-08-02
WO2009079630A1 (fr) 2009-06-25
JP2011507887A (ja) 2011-03-10
BRPI0821394A2 (pt) 2015-06-16
AU2008338374A1 (en) 2009-06-25
ZA201005086B (en) 2011-03-30
EP2234983A1 (fr) 2010-10-06

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead

Effective date: 20121218