ZA201005086B - 4-imidazolidinones as kv1.5 potassium channel inhibitors - Google Patents

4-imidazolidinones as kv1.5 potassium channel inhibitors

Info

Publication number
ZA201005086B
ZA201005086B ZA2010/05086A ZA201005086A ZA201005086B ZA 201005086 B ZA201005086 B ZA 201005086B ZA 2010/05086 A ZA2010/05086 A ZA 2010/05086A ZA 201005086 A ZA201005086 A ZA 201005086A ZA 201005086 B ZA201005086 B ZA 201005086B
Authority
ZA
South Africa
Prior art keywords
imidazolidinones
potassium channel
channel inhibitors
inhibitors
potassium
Prior art date
Application number
ZA2010/05086A
Inventor
James M Ii Ridgeway
Shengde Wu
Benjamin E Blass
John Michael Janusz
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of ZA201005086B publication Critical patent/ZA201005086B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA2010/05086A 2007-12-19 2010-07-16 4-imidazolidinones as kv1.5 potassium channel inhibitors ZA201005086B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1493707P 2007-12-19 2007-12-19
PCT/US2008/087459 WO2009079630A1 (en) 2007-12-19 2008-12-18 4-imidazolidinones as kv1.5 potassium channel inhibitors

Publications (1)

Publication Number Publication Date
ZA201005086B true ZA201005086B (en) 2011-03-30

Family

ID=40379648

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2010/05086A ZA201005086B (en) 2007-12-19 2010-07-16 4-imidazolidinones as kv1.5 potassium channel inhibitors

Country Status (8)

Country Link
EP (1) EP2234983A1 (en)
JP (1) JP2011507887A (en)
AU (1) AU2008338374A1 (en)
BR (1) BRPI0821394A2 (en)
CA (1) CA2709187A1 (en)
MX (1) MX2010006926A (en)
WO (1) WO2009079630A1 (en)
ZA (1) ZA201005086B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO3175985T3 (en) 2011-07-01 2018-04-28
CA2862670A1 (en) 2012-01-27 2013-08-01 Gilead Sciences, Inc. Combination therapies using late sodium ion channel blockers and potassium ion channel blockers
WO2014134419A1 (en) 2013-03-01 2014-09-04 Gilead Sciences, Inc. Use of ikach blockers for the treatment of cardiac diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY125533A (en) * 1999-12-06 2006-08-30 Bristol Myers Squibb Co Heterocyclic dihydropyrimidine compounds
US20070299072A1 (en) * 2006-06-20 2007-12-27 Wyeth Kv1.5 potassium channel inhibitors

Also Published As

Publication number Publication date
CA2709187A1 (en) 2009-06-25
AU2008338374A1 (en) 2009-06-25
BRPI0821394A2 (en) 2015-06-16
WO2009079630A1 (en) 2009-06-25
MX2010006926A (en) 2010-08-02
JP2011507887A (en) 2011-03-10
EP2234983A1 (en) 2010-10-06

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