NO314836B1 - Fremgangsmåte og apparat for behandling av et findelt, pulverisert legemiddel, anvendelse av apparatet og agglomerater - Google Patents

Fremgangsmåte og apparat for behandling av et findelt, pulverisert legemiddel, anvendelse av apparatet og agglomerater Download PDF

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Publication number
NO314836B1
NO314836B1 NO19961290A NO961290A NO314836B1 NO 314836 B1 NO314836 B1 NO 314836B1 NO 19961290 A NO19961290 A NO 19961290A NO 961290 A NO961290 A NO 961290A NO 314836 B1 NO314836 B1 NO 314836B1
Authority
NO
Norway
Prior art keywords
agglomerates
finely divided
screw feeder
agglomeration
sorting
Prior art date
Application number
NO19961290A
Other languages
English (en)
Norwegian (no)
Other versions
NO961290D0 (no
NO961290L (no
Inventor
Eva Trofast
Johan Falk
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9303214A external-priority patent/SE9303214D0/xx
Priority claimed from SE9304271A external-priority patent/SE9304271D0/xx
Application filed by Astra Ab filed Critical Astra Ab
Publication of NO961290D0 publication Critical patent/NO961290D0/no
Publication of NO961290L publication Critical patent/NO961290L/no
Publication of NO314836B1 publication Critical patent/NO314836B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/20—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by expressing the material, e.g. through sieves and fragmenting the extruded length

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Control Of Multiple Motors (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Control Of Motors That Do Not Use Commutators (AREA)
  • Exchange Systems With Centralized Control (AREA)
  • Stereophonic System (AREA)
  • Glanulating (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
NO19961290A 1993-10-01 1996-03-29 Fremgangsmåte og apparat for behandling av et findelt, pulverisert legemiddel, anvendelse av apparatet og agglomerater NO314836B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE9303214A SE9303214D0 (sv) 1993-10-01 1993-10-01 Process I
SE9304271A SE9304271D0 (sv) 1993-12-22 1993-12-22 Process I
PCT/SE1994/000896 WO1995009615A1 (en) 1993-10-01 1994-09-29 Process i
US08/317,033 US5551489A (en) 1993-10-01 1994-10-03 Agglomeration of finely divided powders

Publications (3)

Publication Number Publication Date
NO961290D0 NO961290D0 (no) 1996-03-29
NO961290L NO961290L (no) 1996-03-29
NO314836B1 true NO314836B1 (no) 2003-06-02

Family

ID=27355730

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19961290A NO314836B1 (no) 1993-10-01 1996-03-29 Fremgangsmåte og apparat for behandling av et findelt, pulverisert legemiddel, anvendelse av apparatet og agglomerater

Country Status (23)

Country Link
US (1) US5551489A (cs)
EP (1) EP0721331B1 (cs)
JP (1) JP3732508B2 (cs)
CN (1) CN1110300C (cs)
AT (1) ATE209903T1 (cs)
AU (1) AU679789B2 (cs)
BR (1) BR9407686A (cs)
CZ (1) CZ289214B6 (cs)
DE (1) DE69429357T2 (cs)
DK (1) DK0721331T3 (cs)
EG (1) EG20677A (cs)
ES (1) ES2166786T3 (cs)
FI (1) FI116364B (cs)
HU (1) HU222355B1 (cs)
IL (1) IL111080A (cs)
NO (1) NO314836B1 (cs)
NZ (1) NZ274277A (cs)
PL (1) PL175564B1 (cs)
PT (1) PT721331E (cs)
RU (1) RU2170082C2 (cs)
SG (1) SG48049A1 (cs)
SK (1) SK283569B6 (cs)
WO (1) WO1995009615A1 (cs)

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DE19522899C1 (de) * 1995-06-23 1996-12-19 Hexal Pharmaforschung Gmbh Verfahren zum kontinuierlichen Ersintern eines Granulats
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US5874064A (en) * 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US20020052310A1 (en) * 1997-09-15 2002-05-02 Massachusetts Institute Of Technology The Penn State Research Foundation Particles for inhalation having sustained release properties
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SE9700135D0 (sv) 1997-01-20 1997-01-20 Astra Ab New formulation
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US6495167B2 (en) 1997-03-20 2002-12-17 Schering Corporation Preparation of powder agglomerates
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Also Published As

Publication number Publication date
PL313765A1 (en) 1996-07-22
PT721331E (pt) 2002-05-31
ES2166786T3 (es) 2002-05-01
JP3732508B2 (ja) 2006-01-05
RU2170082C2 (ru) 2001-07-10
ATE209903T1 (de) 2001-12-15
CZ289214B6 (cs) 2001-12-12
HU222355B1 (hu) 2003-06-28
SK283569B6 (sk) 2003-09-11
HUT74519A (en) 1997-01-28
CZ94296A3 (en) 1996-06-12
SK39196A3 (en) 1997-06-04
CN1110300C (zh) 2003-06-04
NO961290D0 (no) 1996-03-29
EP0721331A1 (en) 1996-07-17
JPH09504224A (ja) 1997-04-28
US5551489A (en) 1996-09-03
IL111080A (en) 1999-08-17
DK0721331T3 (da) 2002-02-11
EG20677A (en) 1999-11-30
IL111080A0 (en) 1994-11-28
FI961430L (fi) 1996-03-29
EP0721331B1 (en) 2001-12-05
FI116364B (fi) 2005-11-15
SG48049A1 (en) 1998-04-17
DE69429357D1 (de) 2002-01-17
CN1132476A (zh) 1996-10-02
AU679789B2 (en) 1997-07-10
FI961430A0 (fi) 1996-03-29
DE69429357T2 (de) 2002-08-14
WO1995009615A1 (en) 1995-04-13
AU7826194A (en) 1995-05-01
NO961290L (no) 1996-03-29
HU9600821D0 (en) 1996-05-28
BR9407686A (pt) 1997-02-04
NZ274277A (en) 1998-01-26
PL175564B1 (pl) 1999-01-29

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