DE69429357D1 - Verfahren i - Google Patents

Verfahren i

Info

Publication number
DE69429357D1
DE69429357D1 DE69429357T DE69429357T DE69429357D1 DE 69429357 D1 DE69429357 D1 DE 69429357D1 DE 69429357 T DE69429357 T DE 69429357T DE 69429357 T DE69429357 T DE 69429357T DE 69429357 D1 DE69429357 D1 DE 69429357D1
Authority
DE
Germany
Prior art keywords
agglomerates
procedure
spheronizing
spheronization
agglomerating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69429357T
Other languages
English (en)
Other versions
DE69429357T2 (de
Inventor
Eva Trofast
Johan Falk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9303214A external-priority patent/SE9303214D0/xx
Priority claimed from SE9304271A external-priority patent/SE9304271D0/xx
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of DE69429357D1 publication Critical patent/DE69429357D1/de
Publication of DE69429357T2 publication Critical patent/DE69429357T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/20—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by expressing the material, e.g. through sieves and fragmenting the extruded length
DE69429357T 1993-10-01 1994-09-29 Verfahren i Expired - Lifetime DE69429357T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE9303214A SE9303214D0 (sv) 1993-10-01 1993-10-01 Process I
SE9304271A SE9304271D0 (sv) 1993-12-22 1993-12-22 Process I
PCT/SE1994/000896 WO1995009615A1 (en) 1993-10-01 1994-09-29 Process i
US08/317,033 US5551489A (en) 1993-10-01 1994-10-03 Agglomeration of finely divided powders

Publications (2)

Publication Number Publication Date
DE69429357D1 true DE69429357D1 (de) 2002-01-17
DE69429357T2 DE69429357T2 (de) 2002-08-14

Family

ID=27355730

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69429357T Expired - Lifetime DE69429357T2 (de) 1993-10-01 1994-09-29 Verfahren i

Country Status (23)

Country Link
US (1) US5551489A (de)
EP (1) EP0721331B1 (de)
JP (1) JP3732508B2 (de)
CN (1) CN1110300C (de)
AT (1) ATE209903T1 (de)
AU (1) AU679789B2 (de)
BR (1) BR9407686A (de)
CZ (1) CZ289214B6 (de)
DE (1) DE69429357T2 (de)
DK (1) DK0721331T3 (de)
EG (1) EG20677A (de)
ES (1) ES2166786T3 (de)
FI (1) FI116364B (de)
HU (1) HU222355B1 (de)
IL (1) IL111080A (de)
NO (1) NO314836B1 (de)
NZ (1) NZ274277A (de)
PL (1) PL175564B1 (de)
PT (1) PT721331E (de)
RU (1) RU2170082C2 (de)
SG (1) SG48049A1 (de)
SK (1) SK283569B6 (de)
WO (1) WO1995009615A1 (de)

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Also Published As

Publication number Publication date
HU222355B1 (hu) 2003-06-28
NO314836B1 (no) 2003-06-02
CZ94296A3 (en) 1996-06-12
RU2170082C2 (ru) 2001-07-10
BR9407686A (pt) 1997-02-04
NZ274277A (en) 1998-01-26
HUT74519A (en) 1997-01-28
SK39196A3 (en) 1997-06-04
FI961430A0 (fi) 1996-03-29
JPH09504224A (ja) 1997-04-28
SK283569B6 (sk) 2003-09-11
ATE209903T1 (de) 2001-12-15
NO961290D0 (no) 1996-03-29
DK0721331T3 (da) 2002-02-11
CN1132476A (zh) 1996-10-02
IL111080A0 (en) 1994-11-28
IL111080A (en) 1999-08-17
NO961290L (no) 1996-03-29
AU7826194A (en) 1995-05-01
DE69429357T2 (de) 2002-08-14
HU9600821D0 (en) 1996-05-28
JP3732508B2 (ja) 2006-01-05
FI961430A (fi) 1996-03-29
WO1995009615A1 (en) 1995-04-13
EP0721331A1 (de) 1996-07-17
US5551489A (en) 1996-09-03
EP0721331B1 (de) 2001-12-05
ES2166786T3 (es) 2002-05-01
PT721331E (pt) 2002-05-31
CN1110300C (zh) 2003-06-04
CZ289214B6 (cs) 2001-12-12
PL313765A1 (en) 1996-07-22
SG48049A1 (en) 1998-04-17
PL175564B1 (pl) 1999-01-29
FI116364B (fi) 2005-11-15
EG20677A (en) 1999-11-30
AU679789B2 (en) 1997-07-10

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