GB1520247A - Pelletised medicament formulations - Google Patents

Pelletised medicament formulations

Info

Publication number
GB1520247A
GB1520247A GB35334/74A GB3533474A GB1520247A GB 1520247 A GB1520247 A GB 1520247A GB 35334/74 A GB35334/74 A GB 35334/74A GB 3533474 A GB3533474 A GB 3533474A GB 1520247 A GB1520247 A GB 1520247A
Authority
GB
United Kingdom
Prior art keywords
agglomerates
microns
medicament
pelletised
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB35334/74A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Ltd
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10376566&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB1520247(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fisons Ltd filed Critical Fisons Ltd
Priority to GB35334/74A priority Critical patent/GB1520247A/en
Priority to IE1645/75A priority patent/IE41586B1/en
Priority to ZA00754765A priority patent/ZA754765B/en
Priority to CY1049A priority patent/CY1049A/en
Priority to IL47829A priority patent/IL47829A/en
Priority to CA232,477A priority patent/CA1072569A/en
Priority to NLAANVRAGE7509080,A priority patent/NL177980C/en
Priority to AR259849A priority patent/AR210997A1/en
Priority to BE158922A priority patent/BE832097A/en
Priority to FI752232A priority patent/FI65547C/en
Priority to DE2535258A priority patent/DE2535258C2/en
Priority to BR7505055*A priority patent/BR7505055A/en
Priority to FR7524631A priority patent/FR2282259A1/en
Priority to HU75FI596A priority patent/HU175594B/en
Priority to ES440139A priority patent/ES440139A1/en
Priority to LU73182A priority patent/LU73182A1/xx
Priority to SE7508967A priority patent/SE440595B/en
Priority to DK360875A priority patent/DK145654C/en
Priority to NO752786A priority patent/NO146660C/en
Priority to JP50096732A priority patent/JPS5910326B2/en
Priority to AU83859/75A priority patent/AU492916B2/en
Priority to DE19772702504 priority patent/DE2702504A1/en
Publication of GB1520247A publication Critical patent/GB1520247A/en
Priority to KE3034A priority patent/KE3034A/en
Priority to HK177/80A priority patent/HK17780A/en
Priority to MY34/81A priority patent/MY8100034A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles

Abstract

1520247 Particulate inhalation FISONS Ltd 24 July 1975 [10 Aug 1974] 35334/74 Heading A5B An inhalation medicament preparation which is suitable for use with a particular inhalator device Specification 1122284 comprises "soft" agglomerates 10 to 1000 microns in diameter of medicament particles at least 20% of which have diameters less than 10 microns. Medicaments specified include disodium cromoglycate isoprenaline and 1, 3- bis(2carboxychromon-5-yloxy)propan-2-ol. The agglomerates may also include a diluent, binder or surface active agent, water colouring or sweetening. They may be prepared by rendering the particles adhesive, e.g. by exposing them to a moist atmosphere and then forcing them through a sieve of suitable mesh size. The agglomerates are normally enclosed in capsules.
GB35334/74A 1974-08-10 1974-08-10 Pelletised medicament formulations Expired GB1520247A (en)

Priority Applications (25)

Application Number Priority Date Filing Date Title
GB35334/74A GB1520247A (en) 1974-08-10 1974-08-10 Pelletised medicament formulations
IE1645/75A IE41586B1 (en) 1974-08-10 1975-07-23 Pelletised medicament formulations
ZA00754765A ZA754765B (en) 1974-08-10 1975-07-23 Pharmaceutical composition in pellet form
CY1049A CY1049A (en) 1974-08-10 1975-07-24 Pelletised medicament formulations
IL47829A IL47829A (en) 1974-08-10 1975-07-28 Medicament in pellet form and its preparation
CA232,477A CA1072569A (en) 1974-08-10 1975-07-29 Pellet form medicament
NLAANVRAGE7509080,A NL177980C (en) 1974-08-10 1975-07-30 METHOD FOR MANUFACTURING A FIXED, INTAKABLE MEDICINE PREPARATION AND CONTAINER CONTAINING SUCH A PREPARATION
AR259849A AR210997A1 (en) 1974-08-10 1975-07-31 METHOD FOR THE PRODUCTION OF THE DRUG DISODIUM CHROMOGLYCATE IN GRANULES FORM.
BE158922A BE832097A (en) 1974-08-10 1975-08-04 MEDICINAL PRODUCTS IN FRIABLE GRANULES SUITABLE FOR INHALATION
FI752232A FI65547C (en) 1974-08-10 1975-08-06 FOERFARANDE FOER FRAMSTAELLNING AV FOER INHALERING AVSEDDA MJUKA DINATRIUMKROMOGLYKATPELLETAR
DE2535258A DE2535258C2 (en) 1974-08-10 1975-08-07 Inhalable drug in pellet form
BR7505055*A BR7505055A (en) 1974-08-10 1975-08-07 PELLET DRUG AND PROCESS OF ITS MANUFACTURE
FR7524631A FR2282259A1 (en) 1974-08-10 1975-08-07 MEDICINAL PRODUCT IN THE FORM OF FRIABLE GRAINS
HU75FI596A HU175594B (en) 1974-08-10 1975-08-08 Process for preparing pharmaceutical preparations formulated in pellets
ES440139A ES440139A1 (en) 1974-08-10 1975-08-08 Improved method for the manufacture of an inhalation medicine in the form of soft granules. (Machine-translation by Google Translate, not legally binding)
NO752786A NO146660C (en) 1974-08-10 1975-08-08 PROCEDURE FOR THE PREPARATION OF SOFT DINATE CHROMOGLYCLE PELLET.
LU73182A LU73182A1 (en) 1974-08-10 1975-08-08
SE7508967A SE440595B (en) 1974-08-10 1975-08-08 PROCEDURE FOR THE PREPARATION OF SOFT DINATE CHROMOGLYCELPELLET CELLS FOR INHALATION
DK360875A DK145654C (en) 1974-08-10 1975-08-08 INHALATION PREPARATION FOR USE IN AN INSUFFLATOR AND PROCEDURE FOR PREPARING THEREOF
JP50096732A JPS5910326B2 (en) 1974-08-10 1975-08-11 Method for manufacturing soft pellet drug
AU83859/75A AU492916B2 (en) 1974-08-10 1975-08-11 Medicament in soft pellet form
DE19772702504 DE2702504A1 (en) 1974-08-10 1977-01-21 PHARMACEUTICALS IN SOFT TABLET OR GRANULE FORM
KE3034A KE3034A (en) 1974-08-10 1980-03-10 Pelletised medicament formulations
HK177/80A HK17780A (en) 1974-08-10 1980-04-03 Pelletised medicament formulations
MY34/81A MY8100034A (en) 1974-08-10 1981-12-30 Pelletised medicament formulations

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB35334/74A GB1520247A (en) 1974-08-10 1974-08-10 Pelletised medicament formulations

Publications (1)

Publication Number Publication Date
GB1520247A true GB1520247A (en) 1978-08-02

Family

ID=10376566

Family Applications (1)

Application Number Title Priority Date Filing Date
GB35334/74A Expired GB1520247A (en) 1974-08-10 1974-08-10 Pelletised medicament formulations

Country Status (21)

Country Link
JP (1) JPS5910326B2 (en)
AR (1) AR210997A1 (en)
BE (1) BE832097A (en)
BR (1) BR7505055A (en)
CA (1) CA1072569A (en)
CY (1) CY1049A (en)
DK (1) DK145654C (en)
FI (1) FI65547C (en)
FR (1) FR2282259A1 (en)
GB (1) GB1520247A (en)
HK (1) HK17780A (en)
HU (1) HU175594B (en)
IE (1) IE41586B1 (en)
IL (1) IL47829A (en)
KE (1) KE3034A (en)
LU (1) LU73182A1 (en)
MY (1) MY8100034A (en)
NL (1) NL177980C (en)
NO (1) NO146660C (en)
SE (1) SE440595B (en)
ZA (1) ZA754765B (en)

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0398631A1 (en) * 1989-05-17 1990-11-22 FISONS plc Pharmaceutical composition
GB2237510A (en) * 1989-11-04 1991-05-08 Danbiosyst Uk Small particle drug compositions for nasal administration
US5198221A (en) * 1989-05-17 1993-03-30 Fisons Plc Pharmaceutical composition
US5551489A (en) * 1993-10-01 1996-09-03 Astra Aktiebolag Agglomeration of finely divided powders
US6102036A (en) * 1994-04-12 2000-08-15 Smoke-Stop Breath activated inhaler
US6284287B1 (en) 1994-07-16 2001-09-04 Asta Medica Ag Particulate formulation for administration by inhalation
US6371171B1 (en) 1993-10-01 2002-04-16 Astra Aktiebolag Agglomeration of finely divided powders
US6436902B1 (en) 1994-12-22 2002-08-20 Astrazeneca Ab Therapeutic preparations for inhalation
US6495167B2 (en) 1997-03-20 2002-12-17 Schering Corporation Preparation of powder agglomerates
US6503537B2 (en) 1997-03-20 2003-01-07 Schering Corporation Preparation of powder agglomerates
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
US6610653B1 (en) 1994-06-23 2003-08-26 Astrazeneca Ab Therapeutic preparation for inhalation
US6623760B1 (en) 1999-01-28 2003-09-23 Schering Corporation Method of preparing particles for agglomeration
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
US6794357B1 (en) 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
US6846801B1 (en) 1993-06-24 2005-01-25 Astrazeneca Ab Systemic administration of a therapeutic preparation
US6884794B2 (en) 2000-04-17 2005-04-26 Chiesi Farmaceutici S.P.A. Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets
US7399528B2 (en) 1999-07-16 2008-07-15 Chiesi Farmaceutici S.P.A. Powder particles with smooth surface for use in inhalation therapy
EP2036544A1 (en) 1997-03-20 2009-03-18 Schering Corporation Dosage form of powder agglomerates
US8871274B2 (en) 2000-04-17 2014-10-28 Vectura Limited Pharmaceutical formulations for dry powder inhalers

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2741202A1 (en) * 1976-09-23 1978-03-30 Fisons Ltd SODIUM CROMOGLYCAT WITH SPECIAL BULK DENSITY
JPS6034925B2 (en) * 1979-07-31 1985-08-12 帝人株式会社 Long-acting nasal preparation and its manufacturing method
DE3636209A1 (en) * 1986-10-24 1988-04-28 Lentia Gmbh METHOD FOR PRODUCING A BINDER-FREE TABLET-TABLE CELIPROLOL HYDROCHLORIDE GRANULATE
TWI225402B (en) 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1812574A1 (en) * 1968-12-04 1970-06-11 Riedel De Haen Ag Process for the production of biocidal granules
GB1381872A (en) * 1971-06-22 1975-01-29 Fisons Ltd Pharmaceutical compositions for inhalation

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198221A (en) * 1989-05-17 1993-03-30 Fisons Plc Pharmaceutical composition
EP0398631A1 (en) * 1989-05-17 1990-11-22 FISONS plc Pharmaceutical composition
GB2237510A (en) * 1989-11-04 1991-05-08 Danbiosyst Uk Small particle drug compositions for nasal administration
GB2237510B (en) * 1989-11-04 1993-09-15 Danbiosyst Uk Small particle drug compositions for nasal administration
US6846801B1 (en) 1993-06-24 2005-01-25 Astrazeneca Ab Systemic administration of a therapeutic preparation
US6794357B1 (en) 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
US5551489A (en) * 1993-10-01 1996-09-03 Astra Aktiebolag Agglomeration of finely divided powders
US6371171B1 (en) 1993-10-01 2002-04-16 Astra Aktiebolag Agglomeration of finely divided powders
US6102036A (en) * 1994-04-12 2000-08-15 Smoke-Stop Breath activated inhaler
US6610653B1 (en) 1994-06-23 2003-08-26 Astrazeneca Ab Therapeutic preparation for inhalation
US6284287B1 (en) 1994-07-16 2001-09-04 Asta Medica Ag Particulate formulation for administration by inhalation
US6436902B1 (en) 1994-12-22 2002-08-20 Astrazeneca Ab Therapeutic preparations for inhalation
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
EP2036544A1 (en) 1997-03-20 2009-03-18 Schering Corporation Dosage form of powder agglomerates
US6495167B2 (en) 1997-03-20 2002-12-17 Schering Corporation Preparation of powder agglomerates
US6503537B2 (en) 1997-03-20 2003-01-07 Schering Corporation Preparation of powder agglomerates
US8173172B2 (en) 1997-03-20 2012-05-08 Schering Corporation Preparation of powder agglomerates
US6623760B1 (en) 1999-01-28 2003-09-23 Schering Corporation Method of preparing particles for agglomeration
US7399528B2 (en) 1999-07-16 2008-07-15 Chiesi Farmaceutici S.P.A. Powder particles with smooth surface for use in inhalation therapy
US6884794B2 (en) 2000-04-17 2005-04-26 Chiesi Farmaceutici S.P.A. Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets
EP1719505A2 (en) 2000-04-17 2006-11-08 CHIESI FARMACEUTICI S.p.A. Pharmaceutical formulations for dry powder inhalers in the form of hard pellets
US7223748B2 (en) 2000-04-17 2007-05-29 Chiesi Farmaceutici S.P.A. Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets
EP2272508A2 (en) 2000-04-17 2011-01-12 Vectura Limited Pharmaceutical Formulations for Dry Powder Inhalers
US8871274B2 (en) 2000-04-17 2014-10-28 Vectura Limited Pharmaceutical formulations for dry powder inhalers
US9566239B2 (en) 2000-04-17 2017-02-14 Vectura Limited Pharmaceutical formulations for dry powder inhalers

Also Published As

Publication number Publication date
SE7508967L (en) 1976-02-11
IE41586L (en) 1976-02-10
DK360875A (en) 1976-02-11
JPS5144625A (en) 1976-04-16
BR7505055A (en) 1976-08-03
NL177980B (en) 1985-08-01
ZA754765B (en) 1976-07-28
FI65547B (en) 1984-02-29
CY1049A (en) 1980-08-01
CA1072569A (en) 1980-02-26
IE41586B1 (en) 1980-02-13
NO752786L (en) 1976-02-11
SE440595B (en) 1985-08-12
KE3034A (en) 1980-03-28
IL47829A (en) 1978-01-31
HK17780A (en) 1980-04-11
BE832097A (en) 1976-02-04
JPS5910326B2 (en) 1984-03-08
FR2282259B1 (en) 1978-11-03
DK145654C (en) 1983-08-15
NO146660B (en) 1982-08-09
AU8385975A (en) 1977-02-24
FI752232A (en) 1976-02-11
DK145654B (en) 1983-01-17
MY8100034A (en) 1981-12-31
NL177980C (en) 1986-01-02
FI65547C (en) 1984-06-11
LU73182A1 (en) 1976-08-13
NL7509080A (en) 1976-02-12
IL47829A0 (en) 1975-10-15
NO146660C (en) 1982-11-17
HU175594B (en) 1980-09-28
FR2282259A1 (en) 1976-03-19
AR210997A1 (en) 1977-10-14

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
704A Declaration that licence is not available as of right for an excepted use (par. 4a/1977)
PE20 Patent expired after termination of 20 years

Effective date: 19950723