GB1520247A - Pelletised medicament formulations - Google Patents

Pelletised medicament formulations

Info

Publication number
GB1520247A
GB1520247A GB3533474A GB3533474A GB1520247A GB 1520247 A GB1520247 A GB 1520247A GB 3533474 A GB3533474 A GB 3533474A GB 3533474 A GB3533474 A GB 3533474A GB 1520247 A GB1520247 A GB 1520247A
Authority
GB
Grant status
Application
Patent type
Prior art keywords
agglomerates
microns
medicament
particles
suitable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3533474A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Ltd
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles

Abstract

1520247 Particulate inhalation FISONS Ltd 24 July 1975 [10 Aug 1974] 35334/74 Heading A5B An inhalation medicament preparation which is suitable for use with a particular inhalator device Specification 1122284 comprises "soft" agglomerates 10 to 1000 microns in diameter of medicament particles at least 20% of which have diameters less than 10 microns. Medicaments specified include disodium cromoglycate isoprenaline and 1, 3- bis(2carboxychromon-5-yloxy)propan-2-ol. The agglomerates may also include a diluent, binder or surface active agent, water colouring or sweetening. They may be prepared by rendering the particles adhesive, e.g. by exposing them to a moist atmosphere and then forcing them through a sieve of suitable mesh size. The agglomerates are normally enclosed in capsules.
GB3533474A 1974-08-10 1974-08-10 Pelletised medicament formulations Expired GB1520247A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB3533474A GB1520247A (en) 1974-08-10 1974-08-10 Pelletised medicament formulations

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
GB3533474A GB1520247A (en) 1974-08-10 1974-08-10 Pelletised medicament formulations
CA 232477 CA1072569A (en) 1974-08-10 1975-07-29 Pellet form medicament
NL7509080A NL177980C (en) 1974-08-10 1975-07-30 Method for the production of a solid, inhalable medicament composition, as well as container, which contains such a composition.
BE158922A BE832097A (en) 1974-08-10 1975-08-04 Drugs in own friable granules inhalation
FI752232A FI65547C (en) 1974-08-10 1975-08-06 Foerfarande Foer framstaellning of Foer inhalering intended one mjuka dinatriumkromoglykatpelletar
FR7524631A FR2282259B1 (en) 1974-08-10 1975-08-07
DE19752535258 DE2535258C2 (en) 1974-08-10 1975-08-07
ES440139A ES440139A1 (en) 1974-08-10 1975-08-08 I improved method for the manufacture of a medicament inhalation in the form of soft pellets.
DK360875A DK145654C (en) 1974-08-10 1975-08-08 Inhalation composition for use in an insufflator and the process for its preparation
LU73182A LU73182A1 (en) 1974-08-10 1975-08-08
JP9673275A JPS5910326B2 (en) 1974-08-10 1975-08-11
DE19772702504 DE2702504A1 (en) 1974-08-10 1977-01-21 Medicines in soft tablet- or koernerform

Publications (1)

Publication Number Publication Date
GB1520247A true true GB1520247A (en) 1978-08-02

Family

ID=10376566

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3533474A Expired GB1520247A (en) 1974-08-10 1974-08-10 Pelletised medicament formulations

Country Status (9)

Country Link
JP (1) JPS5910326B2 (en)
BE (1) BE832097A (en)
CA (1) CA1072569A (en)
DK (1) DK145654C (en)
FI (1) FI65547C (en)
FR (1) FR2282259B1 (en)
GB (1) GB1520247A (en)
LU (1) LU73182A1 (en)
NL (1) NL177980C (en)

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0398631A1 (en) * 1989-05-17 1990-11-22 FISONS plc Pharmaceutical composition
GB2237510A (en) * 1989-11-04 1991-05-08 Danbiosyst Uk Small particle drug compositions for nasal administration
US5198221A (en) * 1989-05-17 1993-03-30 Fisons Plc Pharmaceutical composition
US5551489A (en) * 1993-10-01 1996-09-03 Astra Aktiebolag Agglomeration of finely divided powders
US6102036A (en) * 1994-04-12 2000-08-15 Smoke-Stop Breath activated inhaler
US6284287B1 (en) 1994-07-16 2001-09-04 Asta Medica Ag Particulate formulation for administration by inhalation
US6371171B1 (en) 1993-10-01 2002-04-16 Astra Aktiebolag Agglomeration of finely divided powders
US6436902B1 (en) 1994-12-22 2002-08-20 Astrazeneca Ab Therapeutic preparations for inhalation
US6495167B2 (en) 1997-03-20 2002-12-17 Schering Corporation Preparation of powder agglomerates
US6503537B2 (en) 1997-03-20 2003-01-07 Schering Corporation Preparation of powder agglomerates
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
US6610653B1 (en) 1994-06-23 2003-08-26 Astrazeneca Ab Therapeutic preparation for inhalation
US6623760B1 (en) 1999-01-28 2003-09-23 Schering Corporation Method of preparing particles for agglomeration
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
US6794357B1 (en) 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
US6846801B1 (en) 1993-06-24 2005-01-25 Astrazeneca Ab Systemic administration of a therapeutic preparation
US6884794B2 (en) 2000-04-17 2005-04-26 Chiesi Farmaceutici S.P.A. Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets
US7399528B2 (en) 1999-07-16 2008-07-15 Chiesi Farmaceutici S.P.A. Powder particles with smooth surface for use in inhalation therapy
EP2036544A1 (en) 1997-03-20 2009-03-18 Schering Corporation Dosage form of powder agglomerates
US8871274B2 (en) 2000-04-17 2014-10-28 Vectura Limited Pharmaceutical formulations for dry powder inhalers

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2741202C2 (en) * 1976-09-23 1987-09-10 Fisons Plc, Ipswich, Suffolk, Gb
JPS6034925B2 (en) * 1979-07-31 1985-08-12 Teijin Ltd
DE3636209A1 (en) * 1986-10-24 1988-04-28 Lentia Gmbh A process for preparing a binder-free granules tablettierfaehigen celiprolol hydrochloride
EP0896526A1 (en) 1996-03-13 1999-02-17 Biochemie Gesellschaft M.B.H. Agglomerates containing beta-lactam compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1812574A1 (en) * 1968-12-04 1970-06-11 Riedel De Haen Ag A process for preparing a biocidal granules
GB1381872A (en) * 1971-06-22 1975-01-29 Fisons Ltd Pharmaceutical compositions for inhalation

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0398631A1 (en) * 1989-05-17 1990-11-22 FISONS plc Pharmaceutical composition
US5198221A (en) * 1989-05-17 1993-03-30 Fisons Plc Pharmaceutical composition
GB2237510A (en) * 1989-11-04 1991-05-08 Danbiosyst Uk Small particle drug compositions for nasal administration
GB2237510B (en) * 1989-11-04 1993-09-15 Danbiosyst Uk Small particle drug compositions for nasal administration
US6794357B1 (en) 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
US6846801B1 (en) 1993-06-24 2005-01-25 Astrazeneca Ab Systemic administration of a therapeutic preparation
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
US6371171B1 (en) 1993-10-01 2002-04-16 Astra Aktiebolag Agglomeration of finely divided powders
US5551489A (en) * 1993-10-01 1996-09-03 Astra Aktiebolag Agglomeration of finely divided powders
US6102036A (en) * 1994-04-12 2000-08-15 Smoke-Stop Breath activated inhaler
US6610653B1 (en) 1994-06-23 2003-08-26 Astrazeneca Ab Therapeutic preparation for inhalation
US6284287B1 (en) 1994-07-16 2001-09-04 Asta Medica Ag Particulate formulation for administration by inhalation
US6436902B1 (en) 1994-12-22 2002-08-20 Astrazeneca Ab Therapeutic preparations for inhalation
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
EP2036544A1 (en) 1997-03-20 2009-03-18 Schering Corporation Dosage form of powder agglomerates
US6503537B2 (en) 1997-03-20 2003-01-07 Schering Corporation Preparation of powder agglomerates
US6495167B2 (en) 1997-03-20 2002-12-17 Schering Corporation Preparation of powder agglomerates
US8173172B2 (en) 1997-03-20 2012-05-08 Schering Corporation Preparation of powder agglomerates
US6623760B1 (en) 1999-01-28 2003-09-23 Schering Corporation Method of preparing particles for agglomeration
US7399528B2 (en) 1999-07-16 2008-07-15 Chiesi Farmaceutici S.P.A. Powder particles with smooth surface for use in inhalation therapy
US7223748B2 (en) 2000-04-17 2007-05-29 Chiesi Farmaceutici S.P.A. Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets
EP1719505A2 (en) 2000-04-17 2006-11-08 CHIESI FARMACEUTICI S.p.A. Pharmaceutical formulations for dry powder inhalers in the form of hard pellets
EP2272508A2 (en) 2000-04-17 2011-01-12 Vectura Limited Pharmaceutical Formulations for Dry Powder Inhalers
US6884794B2 (en) 2000-04-17 2005-04-26 Chiesi Farmaceutici S.P.A. Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets
US8871274B2 (en) 2000-04-17 2014-10-28 Vectura Limited Pharmaceutical formulations for dry powder inhalers
US9566239B2 (en) 2000-04-17 2017-02-14 Vectura Limited Pharmaceutical formulations for dry powder inhalers

Also Published As

Publication number Publication date Type
LU73182A1 (en) 1976-08-13 application
NL7509080A (en) 1976-02-12 application
FI752232A (en) 1976-02-11 application
FI65547B (en) 1984-02-29 application
CA1072569A1 (en) grant
JPS5144625A (en) 1976-04-16 application
DK360875A (en) 1976-02-11 application
JP1236703C (en) grant
DK145654C (en) 1983-08-15 grant
DK145654B (en) 1983-01-17 grant
NL177980B (en) 1985-08-01 application
JPS5910326B2 (en) 1984-03-08 grant
FR2282259B1 (en) 1978-11-03 grant
CA1072569A (en) 1980-02-26 grant
BE832097A1 (en) grant
NL177980C (en) 1986-01-02 grant
BE832097A (en) 1976-02-04 grant
FR2282259A1 (en) 1976-03-19 application
FI65547C (en) 1984-06-11 grant

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Legal Events

Date Code Title Description
PS Patent sealed
704A Declaration that licence is not available as of right for an excepted use (par. 4a/1977)
PE20 Patent expired after termination of 20 years

Effective date: 19950723