GB1381872A - Pharmaceutical compositions for inhalation - Google Patents

Pharmaceutical compositions for inhalation

Info

Publication number
GB1381872A
GB1381872A GB2920771A GB2920771A GB1381872A GB 1381872 A GB1381872 A GB 1381872A GB 2920771 A GB2920771 A GB 2920771A GB 2920771 A GB2920771 A GB 2920771A GB 1381872 A GB1381872 A GB 1381872A
Authority
GB
United Kingdom
Prior art keywords
inhalation
june
microns
particle size
medicament
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2920771A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Ltd
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fisons Ltd filed Critical Fisons Ltd
Priority to GB2920771A priority Critical patent/GB1381872A/en
Priority to ZA723999A priority patent/ZA723999B/en
Priority to CA144,512A priority patent/CA970685A/en
Priority to NLAANVRAGE7208207,A priority patent/NL176743C/en
Priority to DE2229981A priority patent/DE2229981C3/en
Priority to DK309072AA priority patent/DK134970B/en
Priority to FR7222310A priority patent/FR2143163B2/fr
Priority to AU43805/72A priority patent/AU462722B2/en
Priority to JP48050403A priority patent/JPS5046820A/ja
Publication of GB1381872A publication Critical patent/GB1381872A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Otolaryngology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1381872 Compositions for inhalation FISONS Ltd 1 June 1972 [22 June 1971] 29207/71 Heading A5B A pharmaceutical powder composition comprises a mixture of a solid inhalation medicament having an effective particle size, (as defined), in the range 0.01 to 10 microns, and a solid carrier acceptable in the lungs, having an effective particle size in the range of from 80 to 150 microns. Suitable medicaments include the di-sodium salt of 5, 5'-[(5, 5'-(2-hydroxytrimethylene) dioxy) bis (4-oxo-4H-1-benzopyran-2-yl)] tetrazole, sodium cromoglycate, isoprenaline, ephedrine, adrenaline, theophylline, tetracycline, steroids, enzymes, vitamins, antihistamines, N-acetyl cysteine or its salts, propyliodone, tantalum and paracetamol. The carrier may be coated with a material such as stearic acid or polyvinyl pyrrolidone which may give a sustained release action to the medicament.
GB2920771A 1971-06-22 1971-06-22 Pharmaceutical compositions for inhalation Expired GB1381872A (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
GB2920771A GB1381872A (en) 1971-06-22 1971-06-22 Pharmaceutical compositions for inhalation
ZA723999A ZA723999B (en) 1971-06-22 1972-06-12 Pharmaceutical powder composition suitable for inhalation
CA144,512A CA970685A (en) 1971-06-22 1972-06-13 Composition containing inhalation medicaments
NLAANVRAGE7208207,A NL176743C (en) 1971-06-22 1972-06-15 IMPROVEMENT OF THE METHOD ACCORDING TO PATENT 161.984 FOR THE PREPARATION OF A PHARMACEUTICAL POWDER-INHALED PREPARATION, AND A CONTAINER CONTAINING SUCH A PREPARATION.
DE2229981A DE2229981C3 (en) 1971-06-22 1972-06-20 Pharmaceutical powder preparations
DK309072AA DK134970B (en) 1971-06-22 1972-06-21 Process for the preparation of a pharmaceutical agent intended for inhalation in powder form.
FR7222310A FR2143163B2 (en) 1971-06-22 1972-06-21
AU43805/72A AU462722B2 (en) 1971-06-22 1972-06-22 Pharmaceutical powder composition for inhalation
JP48050403A JPS5046820A (en) 1971-06-22 1973-05-08

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2920771A GB1381872A (en) 1971-06-22 1971-06-22 Pharmaceutical compositions for inhalation

Publications (1)

Publication Number Publication Date
GB1381872A true GB1381872A (en) 1975-01-29

Family

ID=10287853

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2920771A Expired GB1381872A (en) 1971-06-22 1971-06-22 Pharmaceutical compositions for inhalation

Country Status (9)

Country Link
JP (1) JPS5046820A (en)
AU (1) AU462722B2 (en)
CA (1) CA970685A (en)
DE (1) DE2229981C3 (en)
DK (1) DK134970B (en)
FR (1) FR2143163B2 (en)
GB (1) GB1381872A (en)
NL (1) NL176743C (en)
ZA (1) ZA723999B (en)

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0067130A2 (en) * 1981-06-04 1982-12-15 LABORATORIO FARMACEUTICO LOFARMA S.a.s. An allergen dry powder composition and process for its preparation
US4515805A (en) * 1980-11-05 1985-05-07 Fisons Plc Soluble sodium cromoglycate compositions
US6153224A (en) * 1995-01-31 2000-11-28 Co-Ordinated Drug Development Limited Carrier particles for use in dry powder inhalers
US6183782B1 (en) 1994-03-15 2001-02-06 Glaxo Group Limited Inhalation composition containing lactose pellets
WO2001026630A1 (en) * 1999-10-12 2001-04-19 Kaken Pharmaceutical Co., Ltd. Powdery inhalational preparations and process for producing the same
US6221338B1 (en) 1993-10-26 2001-04-24 Vectura Limited Method of producing particles for use in dry powder inhalers
US6284287B1 (en) 1994-07-16 2001-09-04 Asta Medica Ag Particulate formulation for administration by inhalation
US6475523B1 (en) 1995-07-24 2002-11-05 Vectura Limited Powders comprising anti-adherant materials for use in dry powder inhalers
US6884794B2 (en) 2000-04-17 2005-04-26 Chiesi Farmaceutici S.P.A. Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets
WO2005046586A2 (en) 2003-11-04 2005-05-26 Glaxo Group Limited M3 muscarinic acetylcholine receptor antagonists
WO2005104745A2 (en) 2004-04-27 2005-11-10 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
US7399528B2 (en) 1999-07-16 2008-07-15 Chiesi Farmaceutici S.P.A. Powder particles with smooth surface for use in inhalation therapy
US7541022B2 (en) 2000-04-17 2009-06-02 Vectura Limited Pharmaceutical formulations for dry powder inhalers
EP2283817B1 (en) 2000-11-30 2016-05-18 Vectura Limited Method of making particles for use in a pharmaceutical composition
US9365905B2 (en) 2005-02-10 2016-06-14 Dmv-Fonterra Excipients Technology Gmbh Processes for making lactose utilizing pre-classification techniques and pharmaceutical formulations formed therefrom
US10238601B2 (en) 2000-11-30 2019-03-26 Vectura Limited Particles for use in a pharmaceutical composition
EP2266549B1 (en) 2000-06-27 2019-08-07 Vectura Limited Method of making particles for use in a pharmaceutical composition
WO2020031119A1 (en) 2018-08-07 2020-02-13 Norton (Waterford) Limited Application of raman spectroscopy for the manufacture of inhalation powders
US11090294B2 (en) 2009-12-01 2021-08-17 Glaxo Group Limited Combinations of a muscarinic receptor antagonist and a beta-2 adrenoreceptor agonist
US11116721B2 (en) 2009-02-26 2021-09-14 Glaxo Group Limited Pharmaceutical formulations comprising 4-{(1R)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl) phenol
EP4316473A2 (en) 2013-03-28 2024-02-07 Vectura Limited Use of stearate in an inhalable formulation

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2332663C2 (en) * 1973-06-23 1986-07-31 Schering AG, 1000 Berlin und 4709 Bergkamen Use of corticosteroid active ingredients for inhalation therapy
GB1520247A (en) * 1974-08-10 1978-08-02 Fisons Ltd Pelletised medicament formulations
GB1571629A (en) * 1977-11-30 1980-07-16 Fisons Ltd Pharmaceutical compositions containing beclomethasone dipropionate
JPS6034925B2 (en) * 1979-07-31 1985-08-12 帝人株式会社 Long-acting nasal preparation and its manufacturing method
EP0266443B1 (en) * 1986-11-03 1993-06-23 Allen W. Jacobs Process for the inclusion of a solid particulate component into aerosol formulations of inhalable nicotine
JPS59163313A (en) * 1983-03-09 1984-09-14 Teijin Ltd Peptide hormone composition for nasal administration

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1122284A (en) * 1965-03-19 1968-08-07 Fisons Pharmaceuticals Ltd Inhalation device
GB1242211A (en) * 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition

Cited By (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4515805A (en) * 1980-11-05 1985-05-07 Fisons Plc Soluble sodium cromoglycate compositions
FR2512670A1 (en) * 1981-06-04 1983-03-18 Lofarma Farma Lab CAPSULES CONTAINING THE ACTIVE INGREDIENT OF AN ALLERGEN AND PROCESS FOR THEIR PREPARATION
EP0067130A3 (en) * 1981-06-04 1984-01-11 Lofarma Farma Lab Capsules containing the active principle of an allergen, and process for their preparation
EP0067130A2 (en) * 1981-06-04 1982-12-15 LABORATORIO FARMACEUTICO LOFARMA S.a.s. An allergen dry powder composition and process for its preparation
US6582678B2 (en) 1993-10-26 2003-06-24 Vectura Limited Carrier particles for use in dry powder inhalers
US6221338B1 (en) 1993-10-26 2001-04-24 Vectura Limited Method of producing particles for use in dry powder inhalers
US8137657B2 (en) 1993-10-26 2012-03-20 Vectura Limited Carrier particles for use in dry powder inhalers
US6183782B1 (en) 1994-03-15 2001-02-06 Glaxo Group Limited Inhalation composition containing lactose pellets
US6955824B1 (en) 1994-03-15 2005-10-18 Glaxo Group Limited Inhalation composition containing lactose pellets
US6284287B1 (en) 1994-07-16 2001-09-04 Asta Medica Ag Particulate formulation for administration by inhalation
US8920781B2 (en) 1995-01-31 2014-12-30 Vectura Limited Carrier particles for use in dry powder inhalers
US7718163B2 (en) 1995-01-31 2010-05-18 Vectura Limited (01696917) Carrier particles for use in dry powder inhalers
US7011818B2 (en) 1995-01-31 2006-03-14 Vectura Limited Carrier particles for use in dry powder inhalers
US6153224A (en) * 1995-01-31 2000-11-28 Co-Ordinated Drug Development Limited Carrier particles for use in dry powder inhalers
US6475523B1 (en) 1995-07-24 2002-11-05 Vectura Limited Powders comprising anti-adherant materials for use in dry powder inhalers
US7399528B2 (en) 1999-07-16 2008-07-15 Chiesi Farmaceutici S.P.A. Powder particles with smooth surface for use in inhalation therapy
WO2001026630A1 (en) * 1999-10-12 2001-04-19 Kaken Pharmaceutical Co., Ltd. Powdery inhalational preparations and process for producing the same
US7022311B1 (en) 1999-10-12 2006-04-04 Kaken Pharmaceutical Co., Ltd. Powdery inhalational preparations and process for producing the same
US7541022B2 (en) 2000-04-17 2009-06-02 Vectura Limited Pharmaceutical formulations for dry powder inhalers
US8871274B2 (en) 2000-04-17 2014-10-28 Vectura Limited Pharmaceutical formulations for dry powder inhalers
EP1719505A2 (en) 2000-04-17 2006-11-08 CHIESI FARMACEUTICI S.p.A. Pharmaceutical formulations for dry powder inhalers in the form of hard pellets
US7223748B2 (en) 2000-04-17 2007-05-29 Chiesi Farmaceutici S.P.A. Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets
EP2272508A2 (en) 2000-04-17 2011-01-12 Vectura Limited Pharmaceutical Formulations for Dry Powder Inhalers
US9566239B2 (en) 2000-04-17 2017-02-14 Vectura Limited Pharmaceutical formulations for dry powder inhalers
US6884794B2 (en) 2000-04-17 2005-04-26 Chiesi Farmaceutici S.P.A. Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets
EP2266549B1 (en) 2000-06-27 2019-08-07 Vectura Limited Method of making particles for use in a pharmaceutical composition
US10449161B2 (en) 2000-11-30 2019-10-22 Vectura Limited Pharmaceutical compositions for inhalation
EP2283817B1 (en) 2000-11-30 2016-05-18 Vectura Limited Method of making particles for use in a pharmaceutical composition
US10973771B2 (en) 2000-11-30 2021-04-13 Vectura Limited Method of making particles for use in a pharmaceutical composition
US9931304B2 (en) 2000-11-30 2018-04-03 Vectura Limited Method of making particles for use in a pharmaceutical composition
US9962338B2 (en) 2000-11-30 2018-05-08 Vectura Limited Method of making particles for use in a pharmaceutical composition
US10188612B2 (en) 2000-11-30 2019-01-29 Vectura Limited Pharmaceutical compositions for inhalation
US10238601B2 (en) 2000-11-30 2019-03-26 Vectura Limited Particles for use in a pharmaceutical composition
WO2005046586A2 (en) 2003-11-04 2005-05-26 Glaxo Group Limited M3 muscarinic acetylcholine receptor antagonists
WO2005104745A2 (en) 2004-04-27 2005-11-10 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
EP2570128A1 (en) 2004-04-27 2013-03-20 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
US9365905B2 (en) 2005-02-10 2016-06-14 Dmv-Fonterra Excipients Technology Gmbh Processes for making lactose utilizing pre-classification techniques and pharmaceutical formulations formed therefrom
US11116721B2 (en) 2009-02-26 2021-09-14 Glaxo Group Limited Pharmaceutical formulations comprising 4-{(1R)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl) phenol
US11090294B2 (en) 2009-12-01 2021-08-17 Glaxo Group Limited Combinations of a muscarinic receptor antagonist and a beta-2 adrenoreceptor agonist
EP4316473A2 (en) 2013-03-28 2024-02-07 Vectura Limited Use of stearate in an inhalable formulation
WO2020031119A1 (en) 2018-08-07 2020-02-13 Norton (Waterford) Limited Application of raman spectroscopy for the manufacture of inhalation powders
EP3910324A1 (en) 2018-08-07 2021-11-17 Norton (Waterford) Limited Application of raman spectroscopy for the manufacture of inhalation powders

Also Published As

Publication number Publication date
AU4380572A (en) 1974-01-03
NL176743B (en) 1985-01-02
CA970685A (en) 1975-07-08
JPS5046820A (en) 1975-04-25
DK134970C (en) 1977-07-18
DK134970B (en) 1977-02-21
FR2143163B2 (en) 1975-10-31
DE2229981B2 (en) 1980-07-03
DE2229981A1 (en) 1972-12-28
ZA723999B (en) 1973-06-27
AU462722B2 (en) 1975-07-03
NL176743C (en) 1985-06-03
FR2143163A2 (en) 1973-02-02
NL7208207A (en) 1972-12-28
DE2229981C3 (en) 1981-04-02

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee